During DNA replication, the original DNA strand is first separated or “unzipped” into two strands by breaking hydrogen bonds between the base pairs. Each strand serves as a template.

Each “template” strand is then replicated through the attachment of complementary bases. The addition of new nucleotides will always follow the proper base pairing rules (A-T and C-G).

The DNA is found in the chromosome of a eukaryotic cell’s nucleus. In the chromosome, the DNA is tightly coiled around proteins which are called histones.

In the chromosome of eukaryotes, the DNA is coiled around proteins which are called histones. The DNA and protein form a beadlike structure called nucleosome. In turn, the nucleosomes are tightly coiled to produce chromatin fibers, then these fibers are supercoiled to form chromosomes.

In the chromosome of eukaryotes, the DNA is coiled around proteins that are called histones, and together, they form a beadlike structure called nucleosome.

DNA polymerase joins nucleotides together to produce a DNA molecule. Polymerase is the primary enzyme used in DNA replication.

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The chromosomes in prokaryotes are circular in shape and they form a loop. They are found in the cytoplasm. Usually, prokaryotes have a single chromosome, whereas the number of chromosomes in eukaryotes varies per species. The chromosomes in eukaryotes are found in their nucleus. They have a packaging feature that is different from prokaryotes. Eukaryotic chromosomes have a tightly coiled packaging that is enclosed in the nuclear membrane and they appear linear rather than circular.