Epstein Barr Virus – Virology Latency -allows for what? 2

ALL herpes viruses allow for cancer and delayed symptoms More test answers on https://studyhippo.com/combo-with-epstein-barr-virus-and-1-other/

Genes Involved in EBV Carcinogenesis Epstein Barr Virus Nuclear Antigen 1 (EBNA1) -MOA= cancer

-Transactivation of EBV transforming genes (LMP1 and LMP2) – Inhibition of Apoptosis More test answers on https://studyhippo.com/combo-with-epstein-barr-virus-and-1-other/

Epstein Barr Virus – Virology Heterophile Antibodies

random antibodies to seemingly random antigens More test answers on https://studyhippo.com/combo-with-epstein-barr-virus-and-1-other/

Epstein Barr Virus mechanism of infection

Uses C3d component of complement system for attachment and entry. Replication in epithelial and B CELLS More test answers on https://studyhippo.com/combo-with-epstein-barr-virus-and-1-other/

Epstein Barr Virus viral family genome

Herpesviridae family member Enveloped dsDNA virus More test answers on https://studyhippo.com/combo-with-epstein-barr-virus-and-1-other/

Epstein Barr Virus – MOA 5 steps

1. infect B cell 2. cause B cell to proliferate and told to produce antibodies to EBV virus and other random antigens= heterophiles antibodies 3. T cells rec. infection and being fighting off infection 4. few b cells escape forming memory b cells -have EBV virus in genome in latent phase 5. stim–> moment from latency to productive phase–> asymptomatic shedding in saliva More test answers on https://studyhippo.com/combo-with-epstein-barr-virus-and-1-other/

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Epstein Barr Virus Flashcards, test questions and answers

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What is Epstein Barr Virus?

Epstein-Barr virus (EBV) is one of the most common viruses in humans and is a member of the herpesvirus family. It is responsible for causing infectious mononucleosis, also known as mono or the kissing disease. EBV is highly contagious and can be spread through saliva, which explains why it’s sometimes called the kissing disease. It can also be spread through other body fluids such as blood, semen and breast milk. Symptoms of EBV include fever, sore throat, swollen lymph nodes, fatigue and an enlarged spleen. Treatment typically includes rest and over-the-counter medications to help relieve symptoms such as pain relievers and antihistamines. In some cases, antibiotics may be prescribed to prevent secondary infections or if mono becomes severe. Most people contract EBV during their teenage years but adults can still contract it if they come into contact with someone who has it. Since there are no vaccines available to protect against EBV infection, prevention measures should be taken by avoiding close contact with infected individuals or sharing food/drink items that could contain their saliva. Additionally, good hand washing techniques should always be practiced in order to prevent viral transmission from person to person or via contaminated surfaces or objects. In conclusion, Epstein Barr Virus (EBV) is an extremely common virus that primarily affects adolescents but can still affect adults who come into contact with someone who has it. While there are no vaccines currently available for preventing EBV infection yet, basic prevention guidelines such as avoiding close contact with infected individuals and good hand hygiene practices should always be followed in order to reduce the risk of contracting this virus.