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What happens if a mutation alters the amino acid sequence of the corresponding protein?
-the shape of the protein is change, changing its function
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Which of the following would occur from a mutation in the gene’s promoter region? The sequence of the mature mRNA would change. The ability of pre-mRNA to be properly spliced would change. The ability of mRNA to be translationally regulated would change. The amino acid sequence of the translated protein would be altered. The rate of transcription may increase or decrease.
The rate of transcription may increase or decrease.
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What would result from a single nucleotide deletion (point mutation) within the coding sequence of a structural gene? a silent point mutation with no deleterious effects a missense point mutation resulting in the change of one amino acid a nonsense point mutation resulting in the generation of a premature stop codon a frameshift mutation, producing a different amino acid sequence altogether All of the choices are possible.
a frameshift mutation, producing a different amino acid sequence altogether
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Enzymes that catalyze the same reaction but differ in amino acid sequence are called
isozymes. Correct. The muscle and heart forms of lactate dehydrogenase are examples of isozymes.
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What amino acid sequence does the following DNA nucleotide sequence specify? 3′−TACAGAACGGTA−5′ Express the sequence of amino acids using the three-letter abbreviations, separated by hyphens (e.g., Met-Ser-His-Lys-Gly).
Met-Ser-Cys-His
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During translation, nucleotide base triplets (codons) in mRNA are read in sequence in the 5′ → 3′ direction along the mRNA. Amino acids are specified by the string of codons. What amino acid sequence does the following mRNA nucleotide sequence specify? 5′−AUGGCAAGAAAA−3′ Express the sequence of amino acids using the three-letter abbreviations, separated by hyphens (e.g., Met-Ser-Thr-Lys-Gly).
Met-Ala-Arg-Lys
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tRNA molecules work to _____. A. transcribe DNA to mRNA B. translate DNA to produce a specific amino acid sequence C. transcribe the amino acid sequence to DNA D. translate mRNA to produce a specific amino acid sequence E. none of the above
D. translate mRNA to produce a specific amino acid sequence
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5. What is denaturation? A. A structural change of a protein that results in the loss of its biological properties B. A change in the genetic code of an organism C. A change in the amino acid sequence of a protein causing a disruption of its 3D shape D. The process by which amino acids are broken down and ammonia is released
A. A structural change of a protein that results in the loss of its biological properties
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The base sequence of the gene coding for a short polypeptide is CTACGCTAGGCGATTGACT. What would be the base sequence of the mRNA trancsribed from this gene? Using the genetic code in Figure 10.8A, give the amino acid sequence of the polypeptide translated from this mRNA. (Hint: What is the start codon?)
what is the specific amino acid sequence both GpIb and GpIIb/IIIa bind to in fibrinogen and vWF?
RGD: arginine, glycine, aspartate
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