Researcher in pharmaceutical company designs new protease inhibitor that inhibits replication of HIV in T lymphocytes in culture – Q/A (Question and Answer)
Question
Researcher in pharmaceutical company designs new protease inhibitor that inhibits replication of HIV in T lymphocytes in culture – Q/A (Question and Answer)
Test Answer
Which of following findings is most likely to indicate that compound is working specifically as protease inhibitor?
Answer:
Lack of a mature core.
– “-navir”; assembly of visions depends on HIV protease (pol gene) which cleaves polypeptide products of HIV mRNA into function parts; protease inhibitors prevent maturation of new viruses. 199
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