Exam 3 Biochem-Lecture 28 – Flashcards
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Desaturation of Fatty Acids requires combination of |
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Triacylglycerols are synthesized from: |
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•The first step of Synthesis of Triacylglycerols is formation of ......? |
phosphatidic acid. |
Fatty acyl CoAs are formed ....? |
outside mitochondria |
What is the transport molecule for fatty acids into the mitochondrial matrix??? |
Carnitine |
•FAS are oxidized sequentially how many carbons at a time??? |
•FAS are oxidized sequentially 2 carbons at a time. |
Sequential steps of Fatty Acid b-Oxidation are: |
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Fatty Acid b-Oxidation is Oxidized while attached as: |
•as a thioester to 4-phosphopantetheine of CoA |
Overall yield of Fatty Acid b-Oxidation is |
106 ATPS. |
•b-oxidation oxidizes saturated fatty acids with even or odd number??? |
•b-oxidation oxidizes saturated fatty acids with even number |
In Fatty Acid Oxidation, Odd-chains produces |
propinolyl CoA |
•In Fatty acid Oxidation, Unsaturated fatty acids require ....? |
additional enzymes |
In Fatty Acid Oxidation, a- oxidation is necessary for |
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Ketone Bodies |
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Ketone Bodies formation occurs |
in the mitochondrial matrix |
b-hydroxy-b-methylglutaryl CoA (HMG-CoA) is intermediate in |
b-hydroxy-b-methylglutaryl CoA (HMG-CoA) is intermediate in acetoacetate synthesis from acetyl-CoA. |
In Ketone Body synthesis, 2 acetyl-CoA molecules are condensed to form ...............by b-ketothiolase. |
In Ketone Body synthesis, 2 acetyl-CoA molecules are condensed to form acetoacetyl-CoA by b-ketothiolase. |
In Ketone Bodies synthesis, Acetoacetyl-CoA is condensed with a second acetyl-CoA to form HMG-CoA by what???? |
In Ketone Bodies synthesis, Acetoacetyl-CoA is condensed with a second acetyl-CoA to form HMG-CoA by HMG-CoA synthase. |
In Ketone Bodies synthesis, what is condensed with a second acetyl-CoA to form HMG-CoA by HMG-CoA synthase??? |
In Ketone Bodies synthesis, Acetoacetyl-CoA is condensed with a second acetyl-CoA to form HMG-CoA by HMG-CoA synthase. |
In Ketone Bodies synthesis, Acetoacetyl-CoA is condensed with what to form HMG-CoA by HMG-CoA synthase.??? |
In Ketone Bodies synthesis, Acetoacetyl-CoA is condensed with a second acetyl-CoA to form HMG-CoA by HMG-CoA synthase. |
In Ketone Bodies synthesis, Acetoacetyl-CoA is condensed with a second acetyl-CoA to form what by HMG-CoA synthase??? |
In Ketone Bodies synthesis, Acetoacetyl-CoA is condensed with a second acetyl-CoA to form HMG-CoA by HMG-CoA synthase. |
HMG-CoA is cleaved by HMG-CoA lyase to yield |
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•Acetoacetic acid is reduced to d-b-hydroxy- butyrate by b-hyrdoxybutyrate dehydrogenase to yield hydroxybutyrate at the expense of how many NADH??. |
butyrate by b-hyrdoxybutyrate dehydrogenase to yield hydroxybutyrate at the expense of 1 NADH. |
•What is reduced to d-b-hydroxy- butyrate by b-hyrdoxybutyrate dehydrogenase to yield hydroxybutyrate at the expense of 1 NADH??? |
•Acetoacetic acid is reduced to d-b-hydroxy- butyrate by b-hyrdoxybutyrate dehydrogenase to yield hydroxybutyrate at the expense of 1 NADH. |
•Acetoacetic acid is reduced to what by b-hyrdoxybutyrate dehydrogenase to yield hydroxybutyrate at the expense of 1 NADH??? |
•Acetoacetic acid is reduced to d-b-hydroxy- butyrate by b-hyrdoxybutyrate dehydrogenase to yield hydroxybutyrate at the expense of 1 NADH. |
•Acetoacetic acid spontaneously forms |
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•Absence of HMG-CoA lyase results in HMG-CoA being used for ??? |
cholesterol synthesis |
Ketone Bodies can be used by |
Brain Muscle Other tissues BUT NOT LIVER(Liver can not use ketone bodies)
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