cell cycle pogil – Flashcards
Unlock all answers in this set
Unlock answersquestion
cell grows by produce more proteins and organelles
answer
g1
question
dna replication occurs
answer
s
question
cell prepares for cell division with appearance of centrosomes
answer
g2
question
mitosis and cytokinesis occurs
answer
m
question
g0
answer
in which phase of cell cycle are the cells that do not divide
question
m, g1, g2 (all occur later in phase)
answer
what are the 3 checkpoints
question
g2
answer
what checkpoint would respond to dna completely replicated and checked for errors affect
question
g1 and g2
answer
what checkpoint would respond to ample supply of energy and raw materials available
question
m
answer
what checkpoint would respond to all chromosomes are attached to spindles
question
g1
answer
what checkpoint would respond to adequate room in environment for more cells
question
g1
answer
which checkpoint regulates whether cell is in g0 or not
question
daughter cells too small, might not be able to store enough nutrients to survive
answer
predict result of mutation that allows cell to move past checkpoint g1 even tho cell not grown sufficiently
question
daughter cells wont have enough dna --> may die
answer
predict result of mutation that allows cell to move past checkpoint g2 even tho dna replication has not grown sufficiently
question
chromosomes divide unevenly, one daughter cell might contain more chromosomes than other
answer
predict result of mutation that allows cell to move past checkpoint m even tho chromosomes not prepared for division
question
cdk, cyclin, phosphate
answer
what are the 3 parts of maturation promoting factor (mpf)
question
g1, s, g2
answer
which phases are included in interphase
question
remains constant
answer
describe changes in concentration of cdk as cell moves thru diff phases of cell cycle
question
at beginning of g1 concentration = high, during mitosis concentration = low
answer
describe changes in concentration of cyclin as cell moves thru diff phases of cell cycle
question
when cyclin concentration low, mpf concentration low bc less cyclin to bind to cdk
answer
propose an explanation for change in mpf concentration thru/o cell based on knowledge of concentrations of cdk and cyclin
question
no bc daughter cells = smaller --> concentration = same cyclin must be decomposed bc concentration is 0 at lowest pt
answer
can change in cyclin concentration during mitosis be explained by fact cell divides in two and thus divides material in cell into 2 smaller volumes. if no propose an explanation for the change in its concentration
question
g2 bc concentration of mpf is highest right before mitosis phase
answer
which checkpoint in cell cycle is regulated by concentration of mpf
question
cells would go thru mitosis even if not ready
answer
if cyclin was always available in cell at high concentrations, what effect would this have on the cell cycle
question
if cycling never degrades --> mpf always active and cell pressured to go thru g2 checkpt
answer
how might cell be affected by development of a degradation resistant cyclin mutant
question
g2
answer
which checkpt would a tumor suppressor gene repair dna function
question
g1
answer
which checkpt would a tumor suppressor gene check for adequate room for more cells
question
accel bc codes for cyclin, cyclin allows cell to go thru g2
answer
are proto-oncogenes acceleration or brake pedal
question
brake bc stop cell division if two crowded or when not functioning dna
answer
are tumor suppressor genes acceleration or brake pedal
