Copperacetate Ammonium Nitrate Oxidation Of Benzoin Essay Example

apparatus similar to that.

Reflux apparatus with round-bottom flask Caution: Glacial acetic acid is corrosive. Use a fume hood. Ammonium nitrate INH4N03) is oxidizing and irritating. Copper(ll) acetate [Cu(OAc)2] solution is corrosive and irritating, the solid materials are not soluble in acetic acid at room temperature.

The solids dissolve as the pot is heated for refluxing.

NOTE 1: 2. Refluxing the Reaction Mixture 3. Setting Up the Chromatography System Remove the 25-mL round-bottom flask from the apparatus. Place a magnetic stir bar in the round-bottom flask.

Transfer 6.0 mL of glacial acetic acid, 1.0 g of NH4N03, and 2.0 g of benzoin to the flask. Add 1.5 ml of the Cu(OAc)2 solution. [NOTE 1] condenser. Heat the reaction mixture to boiling and reflux, while stirring, for up to 60 min. Caution: Do not use a Bunsen burner near the flammable 95% ethanol.

Using open-ended capillary tubing and a Bunsen burner, prepare 3-5 micropipettes for TLC spots.

Obtain three 2. 5 x 7. 5-cm silica gel TLC plates. At the top, label the three plates "30 min", "45 min", and "60 min", respectively.

Using a ruler as a straightedge, draw a very faint pencil line across each plate 1 cm from the bottom. Do not cut through the silica el with your marks. Make three small vertical lines that intersect the horizontal line at 6, 12, and 18 mm from the left side of the plate.

Using a pencil, label the plate from left to right below the vertical lines with "Bzo", 'Rxn", and "Bzl". Caution: 3enzil is irritating.

Obtain standard samples of benzoin and benzil from your laboratory instructor. Using a micropipette, spot benzoin at the position labeled Bzo on each

plate. Discard the micropipette. Using a new micropipette, spot benzil at the position marked Bzl on each plate.

Discard Dichloromethane is toxic and irritating. Prepare a developing chamber by adding 6 mL of dichloromethane to a 250-mL beaker.

Add filter paper to the chamber to act as a wick. Cover the chamber with aluminum foil or plastic wrap and set it aside in a fume hood.

Monitoring the Reaction After 30 min, remove the heat from the flask. Allow the reaction mixture to cool for 2 Nork quickly to minimize the time the reflux is interrupted. Remove the condenser from the reflux apparatus. Use a micropipette to spot the reaction mixture on the 30 min TLC plate at the position marked Rxn. Replace the condenser and restart the