VTE 123 – Parasitology Part 1 (Lecture 14) – Flashcards

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2 Types of Endoparasites
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1. Worms 2. Protozoa
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3 Types of Ectoparasites
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1. Ticks 2. Fleas 3. Mites
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Prepatent Period
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Length of time from infection to shedding infective stages or diagnostic stages.
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Definitive Host
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The host in which the sexual reproduction of a parasite takes place.
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Intermediate Host
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A host in which a parasite goes through its larval or developmental stages.
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Paratenic
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Host in which no development of the parasite takes place but the phenomenon aids in the transmission of infection, also called transfer/transport host.
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6 Types of Samples Tested
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1. Stool 2. Blood 3. Urine 4. Sputum 5. Tracheal Wash 6. Lesions
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4 Places to look for Endoparasites to get diagnostic results
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1. Eggs 2. Larvae 3. Antigen-antibody 4. Adults Rarely
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4 Factors of Negative Results
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1. Intermittent Shedding 2. Few Eggs/Larvae 3. Inappropriate Sample 4. Degraded Sample
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4 Common Classes of Endoparasites
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1. Nematodes 2. Cestodes 3. Trematodes 4. Protozoa
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The Largest Group of Parasites Are?
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Nematodes
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Nematodes are Referred to as?
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Roundworms
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6 Common Nematodes
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1. Roundworms 2. Hookworms 3. Whipworms 4. Bloodworms 5. Lungworms 6. Heartworms
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Dioecious
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Having male and female reproductive organs. Reproduce by laying eggs, or larvae which hatch from their eggs inside the body of female worm.
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Majority of Nematodes are?
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Not parasitic, live in soil.
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Ascaridida
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Roundworms
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2 Canine Roundworm Scientific Names
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1. Toxocara canis 2. Toxascaris leonina
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2 Feline Roundworm Scientific Names
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1. Toxocara cati 2. Toxascaris leonina
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Raccoon Roundworm Scientific Name
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Baylisascaris procyonis
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Adult Roundworms Live Where?
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Small Intestine
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Prepatent Period of Nematodes
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20-90 Days
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VLM
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Visceral Larval Migration
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OLM
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Ocular Larval Migration
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General Ascarid Life Cycles
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Ingests larvae/eggs or ingests a host. Infected animal passes Toxocara eggs in feces, milk, and in utero. Toxocara egg is pass in dog feces. Develops in the environment.
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Common Route of Infection for Toxocara canis
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Transplacental transmission of larvae from bitch to fetal pups.
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Life Cycle of Roundworm in the Body
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Larvae migrate through the liver and lungs, are carried up the mucociliary apparatus, then swallowed to develop in small intestine.
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Roundworm Migration in Fetal Pups
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Migrating larvae wait in liver and lungs until pups are born, then resume migration across lungs to airways.
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Roundworm Larvae Acquired from Ingestion of Vertebrate Tissues
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Do not migrate in dog or cat definitive host, they travel to small intestine to become adult worms.
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4 Signs of Roundworm in Puppies
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1. Ill thrift 2. Failure to Gain Weight 3. Poor Hair Coat 4. Pot-bellied Appearance.
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Signs of Roundworm in Cats
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Ill thrift and pot-bellied appearance in kittens. Cats remain susceptible to infection throughout life. Irritation of ascarids migrating from small intestine may cause vomiting.
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Cats are most susceptible to Roundworms what?
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Throughout life.
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T. canis Prepatent Period
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2 to 4 Weeks
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A single adult T. canis can produce as many as ________________________________ eggs per day.
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85,000 to 100,000 eggs per day.
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Heavily infected pups can pass how many roundworms in 1 gram of feces?
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100,000 eggs
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Diagnosis for Toxocara
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Fecal exam for ova.
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5 Treatments of Ascarids
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1. Fenbendazole, milbemycin oxime, and pyrantel pamoate. 2. Selamectin 3. Febantel in combo with pyrantel and praziquantel. 4. Piperazine 5. Pyrantel
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Treatment of Roundworms in Puppies
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Treated with pyrantel pamoate at 2,4,6 and 8 weeks then placed on monthly heartworm preventative.
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Treatment of Roundworms in Kittens
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Do not need to be treated until 6 weeks of age. Treated with pyrantel pamoate at 3,5,7, and 9 weeks of age then placed on monthly heartworm preventative.
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Treatment of Roundworms in Nursing Dams
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Should be treated at the same time as their litters.
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Treatment of Roundworms in Pregnant Bitches
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Daily with fenbendazole or 2 to 4 times with a high dose of Ivermectin to prevent transplacental and transmammary transmission.
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5 Prevention/Control Measures for Roundworm
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1. Remove eggs from environment. 2. Leash Laws 3. Routinely deworming infected animals. 4. Prevention of predation and scavenging. 5. Raccoons not kept as pets and should be discouraged from defecating nearby.
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Strongylida (Stronglids)
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Hookworms
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3 Types of Canine Hookworms
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1. Ancylostoma canium 2. Ancylostoma braziliense 3. Uncinaria stenocephala
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3 Types of Feline Hookworms
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1. Ancylostoma tubaeforme 2. Ancylostoma braziliense 3. Uncinaria stenocephala (rare in cats)
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Where do adult hookworms live?
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Small intestine and shed eggs in feces.
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Which stage of hookworm larvae infects puppies and kittens?
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Ingestion of third-stage larvae from contaminated environment, larval penetration of skin, or ingesting other hosts.
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How can cats also be infected by hookworms?
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Ingesting Cockroaches
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Important Route of Infection of A. caninum
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Transmammary Transmission
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A. tubaeforme is acquired ________________________.
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After birth, not to nursing kittens.
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How are arrested hookworm larvae activated?
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After removal of adult worms from intestine or during pregnancy when they accumulate in mammary glands.
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4 Steps of Hookworm Migration within Host
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1. Skin penetration 2. Carried by bloodstream to lungs. 3. Coughed up and swallowed. 4. Mature, mate, and produce eggs in small intestine.
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Hookworm eggs are found in feces how long after infection?
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2 to 3 weeks.
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Hypobiosis
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Arrested stage of development
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How long do adult hookworms live in the small intestine?
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4 to 24 months
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Hookworms secrete _____________________ and ______________________ to digest intestinal mucosa and facilitate blood feeding.
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Enzymes and Anticoagulants
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Hookworm Platelet Inhibitor
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Inhibits platelet aggregation and adhesion.
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Which hookworm can bleed a puppy to death?
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A. caninum
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Puppies with heavy worm burden will develop?
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Acute Normocytic, Normochromic Anemia followed by Hypochromic, Microcytic Anemia.
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7 Signs of Puppies Infected with Hookworms
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1. Pale MM 2. Anemia 3. Ill Thrift 4. Failure to Gain Weight 5. Poor Hair Coat 6. Dehydration 7. Melena
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A. tubaeforme
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A voracious bloodsucker that causes anemia, diarrhea, and weight loss in kittens.
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Why are A. caninum and A. tubaeforme more pathogenic that U. stenocephala?
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They consume much more blood.
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Penetration of Hookworms can have what 3 effects on the skin?
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Dermatitis with erythema, pruritis, and papules.
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Which type of hookworm prefers colder climates?
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U. stenocephala
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Hookworm deworming does not kill _____________________________.
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Arrested larvae in the tissues.
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3 Modes of Transmission of Hookworm
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1. Ingestion of Infected Larvae 2. Larval Skin Penetration 3. Ingestion of Larvae in Vertebrate Host Tissue.
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2 Ways Hookworm Arrested Larvae are Activated?
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1. During pregnancy they migrate to mammary glands. 2. After antihelmintic treatment when removed from small intestine.
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A. caninum Prepatent Period
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2-3 weeks. As early as 10 to 12 days after birth, puppies can shed eggs.
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A. tubaeforme Prepatent Period
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18-28 days
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A. braziliense and U. stenocephala Prepatent Period
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13 to 27 days
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Hookworm Environmental Conditions
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Thrive best in warm, moderately moist, aerated soils away from sunlight. Can survive for a few months until metabolic reserves are depleted.
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4 Feline Treatments of Hookworm
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1. Ivermectin, milbemycin oxime, moxidectin, and selamectin. 2. Pyrantel and Fenbendazole 3. Pyrantel Pamoate combined with Praziquantel. 4. Emodepside combined with praziquantel.
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2 Canine Hookworm Treatments for A. canium and Uncinaria Infections
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1. Febantel, Milbemycin, and Moxidectin. 2. Fenbendazole, Milbemycin oxime, moxidectin, and Pyrantel pamoate.
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Treatment Protocols for Hookworm in Puppies
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Prevent environmental contamination, treat with Pyrantel at 2, 4, 6, and 8 weeks of age then place on monthly heartworm preventative.
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Treatment Protocols for Hookworm in Kittens
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Pyrantel Pamoate at 3, 5, 7, and 9 weeks of age then put on monthly heartworm preventative.
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Treatment Protocols for Hookworm in Nursing Dams
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Should be treated for hookworms at same time as their litters.
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Treatment Protocols for Hookworms in Pregnant Botches
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Treated during pregnancy with daily fenbendazole or 2 to 4 times with a high dose ivermectin to prevent transplacental and transmammary transmission of hookworm larvae.
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6 Prevention and Control Methods for Hookworm
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1. Treat newly acquired infections. 2. Maintain on monthly intestinal parasite-control products. 3. Initial dewormings 4. Preventing Predation and Scavenging 5. Removal of feces 6. Leash Laws
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3 Chemicals used to Prevent and Control Hookworms
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1. Sodium borate on lawns and gravel 2. 1% bleach solution 3. Flaming surfaces
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Trichuris vulpis occurs in what 3 animals?
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1. Dog 2. Fox 3. Coyote
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3 Common Names for Feline Whipworm
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1. Trichuris felis 2. Trichuris campanula 3. Trichuris serrata
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Is Feline Whipworm Common?
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No, occurs rarely in domestic and wild species.
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Whipworm Characteristics
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Body composed of thin, filamentous, anterior end (the lash) and thick posterior end (the whip's handle).
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Prepatent Period of Whipworms
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70-90 Days
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Whipworm eggs are ______________________ when passed in feces.
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Unembryonated
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Unembryonated Whipworm eggs are resistant to?
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1. Desiccation 2. Extreme Temperatures 3. UV Rays
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Where do Whipworm eggs embryonate and when?
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In the soil depending on temperature and moisture content. Embryonate in 9 to 21 days.
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How are hosts infected by Whipworm?
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Ingesting larvated eggs from soil.
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Where do larvated Whipworm eggs hatch?
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Hatch from eggs in small intestine and penetrate mucosa.
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In 2 to 10 days, Whipworm larvae move to where and become?
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Move to cecum and become adult worms.
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Many Canine Whipworm Infections are __________________ and ___________________.
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Asymptomatic or Subclinical.
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Some infections caused by Whipworm result in ____________________ or ________________.
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Typhilitis or Colitis.
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Adult Whipworms Consume?
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Blood, Tissue Fluids, and Mucosal Epithelium.
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How many eggs can female T. vulpis produce in a day?
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2,000 eggs
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2 Aspects of Whipworm Infection that May Complicate Diagnosis
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1. Long prepatent period causes heavily infected animals may show clinical signs before ova are shed. 2. In low-level infections, ova may be shed intermittently.
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How are Whipworm ova distinguished from Eucoleus spp. and Pearsonema spp. ?
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Whipworm ova are barrel-shaped, yellow-brown. Eoculeus spp. and Pearsonema spp. are smaller and have a rough surface.
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3 Treatments of Whipworm
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1. Single Treatment Products - Drontal Plus 2. Monthly Administration - Interceptor and Sentinel 3. Administered for 3 Consecutive Days - Panacur
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Drontal Plus is made up of?
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Febantel, Pyrantel Pamoate, and Praziquantel.
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Panacur is made of?
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Fenbendazole
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Interceptor and Sentinel are made up of?
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Milbemycin oxime and Sentinel.
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3 Prevention and Control Methods of Whipworm
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1. Removing Feces 2. Deworming Protocols 3. Some Available Monthly Broad-Spectrum Heartworm Prevention
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