Pharm chapter 43 drugs to treat cancer – Flashcards
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Cancer treatment requires
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Combination surgrey, Radiation Chemotherapy Immunotherapy
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Cancer is
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Disorder of cellular growth
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When does cancer occur
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Abnormal cells proliferates more rapidly than normal cells, Losing ability to perform specialized functions
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What is metastasis
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Invades surrounding tissues
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Mitosis
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Phase of growth in which cells divide into two equal daughters
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Cells advance to nonproliferative stage or advance to
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First gap phase
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Nonproliferative stage is
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G0
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G1
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First Gap phase
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Phase G2
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Post synthetic phase
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What happens in post synthetic stage
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Cell prepares for mitosis
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How does cell prepare for mitosis
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By producing RNA
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What is RNA
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Specialized proteins And foundation for mitotic spindle apparatus needed for mitosis
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What is generation time
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Time required to complete a cell cycle
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Cancer cells are more sensitive to chemotherapy during
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Rapid division
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Cell cycle specific
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The drug is selectively toxic
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Cell cycle specific
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Effective against malignancies that proliferate rapidly
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Cell cycle nonspecific
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Active throughout the cell cycle
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Cell cycle nonspecific
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More effective with slowly proliferating neoplastic tissue
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What is a common symptom with most drugs that treat cancer
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Anorexia, nausea, vomiting, GI symptoms, nephrotoxicity, bone marrow depression
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Anorexia is not a common symptom with use of what Chemotherapeutic agent
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Nautural products
