Test Answers on Organic Chemistry – Flashcards
230 test answers
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Ovalbumin |
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Storage egg white protein |
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casein |
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Storage milk protein |
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Ferritin |
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Storage Stores iron in the spleen |
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myoglobin |
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Storage stores O2 in heart muscle |
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immuglobulins |
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Protection antibodies quaternary structure |
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fibrinogen |
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Protection involved in blood clotting |
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thrombin |
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Protection involved in blood clotting |
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insulin |
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Regulation regulates glucose metabolism |
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growth hormone |
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Regulation stimulates growth of bone |
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vasopressin |
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Regulation increase water retention of the kidney |
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oxytocin |
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Regulation lactation, induction of labor |
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acetylcholine receptor protein |
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Nerve impulse transmission synthesized from choline and acetyl-CoA |
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rhodopsin |
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involved in vision |
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hemoglobin |
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transport transport O2 in blood quaternary structure |
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serum albumin |
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transport transport fatty acids |
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serum globulins |
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transport transport lipids (HDL, LDL) |
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myosin |
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motion thick filaments in muscle fiber |
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actin |
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motion thin filaments in muscle fibers |
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glycoproteins |
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Structural cell membranes and walls |
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keratins |
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Structural skin, hair, nails, hoofs |
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fibroin |
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Structural silk |
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collagen |
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Structural Fibrous connective tissue (tendons, teeth, bones) quaternary structure |
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elastin |
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Structural elastic connective tissue (ligaments, artery walls) |
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Saponifiable - simple |
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fats, waxes, oils |
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Saponifiable - complex |
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Phospholipids, Glycolipids |
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Non-Saponifiable |
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steriods, fatty acids, prostaglandins |
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Phospholipids divide into |
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Phosphatides, Sphingolipids |
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Carbohydrates metabolize into |
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Acetyl CoA |
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Acetyl CoA become either |
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Fatty acids (Metabolism) Cholesterol (through liver) |
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Cholesterol comes from |
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some foods (eggs, butter, cheese) Acetyl CoA |
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Cholesterol becomes (5) |
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Bile salts Vitamin D Steroid hormones Cell membranes Nerve and brain tissue |
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excess Cholesterol |
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to gallbladder eliminated on bile or gallstones |
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Oxidoreductases |
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Oxidases Reductases Dehydrogenases |
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Transferases |
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Transaminases Kinases |
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Hydrolases |
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Peptidases Lipases Amylases |
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Lyases |
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Decarboxylases Dehydrases Deaminases |
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Isomerases |
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Isomerases Epimerases Mutases |
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Ligases |
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Synthetases Carboxylases |
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Irreversible |
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attaches to the enzyme permenently but does not form its our reaction |
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Non-competitive |
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does not attach itself to the active site , but somewhere else so it changes the structure of the enzyme |
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Competitive |
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non-reactive molecule that takes the place of the usual substrate on the active site. Can break up. |
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Antagonists |
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inhibits the normal physiological function of a receptor |
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inhibitor |
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effector that decreases or prevents a chemical reaction |
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Agonist |
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binds to a receptor and triggers a responce by the cell. |
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Cofactors |
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non-protein compound that is bound to a protein and is required for protein activity |
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Substrate |
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Acetylcholinesterase |
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Enzyme converts Acetylcholine into inactive choline and acetate |
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egg albumin |
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egg white protein |
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aldosterone |
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steroid hormone produced by outer sections of adrenal cortex |
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apoenzyme |
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enzymes that require a cofactor but do not have one bound |
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Catalytic site |
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active site portion of the enzyme where substrate molecules bind and undergo reaction |
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cholesterol |
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A diet high in carbohydrates will lead to acetyl CoA formation, and that can increase cholesterol synthesis Butter and eggs have a high level of cholesterol can move right through cell membrane w/o a protein channel |
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cortisone |
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steriod hormone released by adreanal gland suppresses the immune system |
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cortisol |
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steriod hormone produced by adreanal gland increase blood sugar, suppress immune system, aid in metabolism |
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holoenzyme |
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an apoenzyme with its cofactor |
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lactic acid |
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milk acid carboxylic acid can become lactate ion sours milk |
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Lactose |
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disaccharide sugar galactose and glucose |
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lecithin |
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phospholipids in animal and plant tissue |
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milk |
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lactose lactic acid |
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myelin |
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myelin sheath on neurons lipids |
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niacin |
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vitamin B3 nicotinic acid dificiency causes pellagra increases levels of HDL |
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Pantothanic acid |
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vitamin B5 water-soluble vitamin essential nutrient to synthesize coenzyme-A |
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peptide bond |
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covalent chemical bond carboxyl group reacts with amino group to release water |
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phospholipase |
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enzyme hydrolyzes phospholipids into fatty acids |
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Proenzymes |
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inactive enzyme precursor |
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prostaglandins |
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synthesized in the cell only when it is needed made from fatty acid found in cell membranes very potent in small quantities they act like hormones |
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Riboflavin |
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vitamin B2 micronutrients component of cofactors FAD and FMN role in energy metabolism and metabolism of fats, ketone bodies, carbohydrates, and proteins |
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thiamine |
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vitamin B1 water-soluble vitamin |
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Vitamin A |
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Lipid-soluble |
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Vitamin C |
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Vitamin D |
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Lipid-soluble |
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Vitamin E |
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Lipid-soluble |
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Vitamin K |
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Lipid-soluble |
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Whey |
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milk serum liquid from curdled and strained milk Whey protein (globular protein) |
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Zymogens |
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inactive enzyme precursor |
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Saturated fats melting point |
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High |
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unsaturated fats melting point |
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Low |
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Unsaturated physical state at room temp |
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liquid |
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saturated physical state at room temp |
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solid |
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esterification |
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fatty acids react with alcohols to form esters and water |
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acid hydrolysis |
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produce fatty acids from esters |
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cell membranes |
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bilayer with the hydrophilic end on the outside contains protein channels to allow small polar molecules and ions to move through polypeptides cannot pass through |
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allosteric enzymes |
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quaternary structure |
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___ levels of LDL are associated with cardiovascular diease |
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High |
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exercise helps ____ the LDL valuses |
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Lower |
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a healthy adult should have a ___ LDL value |
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Low |
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Butter and eggs have a ___ level of cholesterol |
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High |
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A diet high in carbohydrates will lead to ___, and that can increase cholesterol synthesis |
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Acetly CoA formation |
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Which type of bond connecting amino acids is found in the tertiary structure of proteins |
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salt bridges disulfide bonds hydrogen bonding of side chains |
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Polar (neutral) amino acids can bond with what groups? |
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Polar neutral, acidic, and basic |
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Steroid hormones |
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can move right through cell membrane w/o a protein channel |
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CO2 |
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can move right through cell membrane w/o a protein channel |
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Once one molecule of O2 is bound to the heme of hemoglobin, hemoglobin’s ability to bind more oxygen is enhanced. |
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true |
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Enzymes usually react only with one compound in a pair of enantiomeric drugs. |
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true |
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The higher the turnover rate, the more efficient the enzyme. |
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true |
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A cofactor can be either an organic molecule or an inorganic metal, which is necessary for biological activity of an enzyme. |
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true |
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Proteins in solution are actually colloids not really solutions. |
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true |
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Sphingolipids contain a sphingosine backbone instead of glycerol. |
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true |
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Iodine test is the same as the iodine number |
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false |
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Cortisol regulates the conversion of amino acids into carbohydrates |
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true |
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Dilated blood vessels are less permeable |
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false dilated blood vessels are permeable |
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Globular proteins are much more easily denatured than tough fibrous proteins. |
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true |
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Salt bridges are the strongest interaction in the tertiary structure of proteins. |
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False disulfide |
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Alcohol is a diuretic because it inhibits the secretion of vasopressin, (vasopressin increases water retention of the kidney) |
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true |
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A very high pH will permanently denature enzymes but a very low pH will not. |
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False both will |
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Aldosterone and vasopressin have similar effects on water retention in the kidneys. |
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true |
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The diseases Gaucher’s, Niemann-Pick and Tay-Sachs all involve the lack of enzymes needed to control lipid degradation. |
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true |
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Lipids that are saponifiable all have an ester linkage. |
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true |
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Hydrophilic interaction is the weakest interaction in the tertiary structure of proteins. |
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false hydrophobic |
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The redness associated with inflammation is due to the dilated blood vessels, which bring more blood into the area. |
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true |
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High temperatures will permanently denature enzymes but low temperatures will not. |
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true |
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Women tend to have a lower LDL value than men. |
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true |
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Naturally occurring carbohydrates are usually “D”, while amino acids are usually “L” |
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true |
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Acid solutions will turn red litmus paper blue |
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false base solutions |
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Anti-coagulant which is always found in the blood in small quantities |
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heparin |
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Prescription drug given to patients after heart attacks as a blood thinner |
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coumadin |
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Precipitates calcium ions, thus preventing blood clotting |
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oxalate |
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Found in Spinach and Broccolli |
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Vitamin K |
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Analgesic which is not an anti-coagulant |
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acetaminophen |
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What compound causes the conversion of fibrinogen to fibrin? |
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thrombin |
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Which is the actual blood clot? |
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fibrin |
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Which destroys the blood clot after it is no longer needed? |
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plasmin |
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Which is found in blood plasma but not blood serum? |
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fibrinogen |
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Calcium ions are needed for the conversion of what compound to what compound? |
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prothrombin to thrombin |
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Classify: Elastin |
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fibrous proteins |
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Classify: cortisol |
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non-saponifiable lipids |
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Classify: cellulose |
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carbohydrate |
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Classify: aldosterone |
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non-saponifiable lipids |
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Classify: Enzymes |
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globular proteins |
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Classify: Phospholipids |
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saponifiable lipids |
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Classify: hemoglobins |
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globular proteins |
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Classify: prostaglandin |
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non-saponifiable lipids |
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Classify: collagen |
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fibrous proteins |
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Classify:serotonin |
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other |
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Components of lecithin |
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glycerol Fatty acids phosphate and amine alcohol |
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Components of pepsinogen |
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amino acids |
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Components of glycogen |
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glucose |
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Components of maltose |
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glucose |
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Components of maltase |
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amino acids |
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Components of Beeswax |
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Fatty acids |
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Components of estrogen |
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steroid structure |
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Components of arachidonic acid |
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Fatty acids |
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Components of Vasopressin |
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amino acids |
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Components of cornflower oil |
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glycerol Fatty acids |
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Components of triglycerides |
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glycerol Fatty acids |
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Components of polysaccharide |
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glucose |
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It is one of the most abundant proteins in humans |
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Collagen |
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Compound in egg yolks |
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lecithin |
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Compound in egg whites |
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ovalbumin |
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Protein in milk |
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casein |
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Carbohydrate in milk |
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lactose |
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Protein found in connective tissue |
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collagen |
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protein in nails, hair, hoofs |
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keratins |
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blood protein used to maintain osmotic pressure |
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serum albumin |
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common name for immunoglobulins |
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antibodies |
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protein found in LDLs and HDLs |
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serum globulins |
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A clot that breaks loose and moves is called |
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embolism |
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protein in muscle of marine mammals that contains the heme group that binds O2 for storage |
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myoglobin |
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protein in muscle fiber |
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myosin or actin |
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protein that stores iron in the spleen |
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ferritin |
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Polypeptide used to increase water retention of the kidneys |
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Vasopressin |
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Polypeptide used to induce labor |
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Oxytocin |
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The same reaction in different tissues will have similar but slightly different enzymes. What are these enzymes called? |
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isoenzyme |
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What is the enzyme (found in saliva and tears) that destroys a bacteria’s cell wall? |
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lysozyme |
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The drug that prevents a bacteria from making its cell wall |
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Penicillin |
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The drug or poison that blocks the receptor site for acetylcholine on a muscle. |
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Curare |
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The drug or poison that permanently inhibits acetylcholinesterase |
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Nerve gas |
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The drug or poison that prevents acetylcholine from being released on the original nerve cell |
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Botulism |
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Which drug inhibits the enzyme phospholipase from releasing aracadonic acid from the cell membrane? |
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Cortisone (or cortisol) |
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The drug added to penicillin to prevent the bacteria from destroying the antibiotic |
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Clavulinic acid |
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What is the cofactor made from Riboflavin |
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FAD |
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What is the cofactor made from Niacin |
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NAD |
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What is the enzyme without its cofactors called? |
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Apoenzyme |
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What active peptidase is found in the small intestines |
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Trypsin |
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What is referred to as the “feast” hormone? |
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insulin |
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What is referred to as the “famine” hormone? |
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glucagon |
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If an enzyme’s turnover rate is very low, it is a very efficient enzyme. |
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false it is a efficient enzyme |
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Enzymes and substrates are usually held together by disulfide bonds. |
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false enzymes and substrates are not usually held together by disulfide bonds |
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Hormones and enzymes can sometimes be proteins and sometimes non-proteins. |
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false enzymes can only be proteins |
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All enzymes can be affected by substrate saturation. |
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true |
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Doubling the concentration of the substrate will always double the rate of the reaction. |
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false not at the point of saturation |
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All proteins have a quaternary structure |
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false not all proteins have a quaternary structure |
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All enzymes are globular proteins |
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true |
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Proteins are most soluble at their isoelectric point |
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false proteins are soluble at their isoelectric point |
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Bacteria in milk will cause the milk to become more acidic |
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true |
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Denaturing with heavy metals affects the salt bridges in the globular protein |
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true |
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aldosterone is a __ hormone |
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steroid |
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glucagon is a ___ hormone |
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protein |
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keratin is a hormone T/F |
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false |
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what hormone can slide right through the cell membrane? |
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steroid hormone |
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what hormone takes minutes to affect the cell |
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protein hormone |
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____ hormone attaches to a receptor site on the outside of the target cell |
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protein hormone |
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chemical messengers that are produced in one place in the body and affect other parts of the body |
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hormones |
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maltase needs _____ enzyme for the reaction |
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hydrolases |
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A tripeptide to three seperate amino acids needs _____ enzyme for the reaction |
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hydrolases |
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Lactic dehydrogenase needs ____ enzyme |
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oxidoreductases |
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Phosphofructokinase needs _____ enzyme for the reaction |
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transferases |
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alanine transamiinase needs _____ enzyme for the reaction |
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transferases |
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Acetoacetate decarboxylase needs _____ enzyme for the reaction |
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lyases |
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glucose-6-phosphate to fructose-6-phosphate needs _____ enzyme for the reaction |
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isomerase |
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phosphoglucomutase |
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isomerase |
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Citric acid synthetase needs _____ enzyme for the reaction |
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ligase |
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Oxaloacetate & acertyl-CoA to citric acid needs _____ enzyme for the reaction |
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ligase |
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What vitamin is converted into the coenzyme NAD or NADH |
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niacin |
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What vitamin is converted into coenzyme A |
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Pantothenic acid |
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What vitamin is converted into the coenzyme FAD |
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Riboflavin |
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What vitamin is needed for collagen synthesis |
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Vitamin C |
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what vitamin is converted into the coenzyme TPP |
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thiamine |
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Scurvy is caused by the deficiency of what vitamin |
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Vitamin C |
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the rate at which an enzyme will convert substrates to products is called |
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Turnover rate |
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specific area on the enzyme where the chemical reaction takes place |
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Catalytic site |
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specific area on the enzyme where the substrate binds |
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Contact site |
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inactive protein part (without the cofactors) of an enzyme is called |
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Apoenzyme |
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what is the cofactor plus the protein part called |
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holoenzyme |
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what is the cofactor that is organic but not a protein called |
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coenzyme |
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What fiborous protein has a triple helix structure |
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collagen |
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what protein is found in muscle fiber (2) |
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actin or myosin |
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What protein is found in artery walls and ligaments |
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elastin |
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what protein is used to store iron in the spleen |
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ferritin |
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protein found in bones and connective tissue |
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collagen |
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Protein used to store oxygen in heart muscles (humans) and marine mammal muscles |
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myoglobin |
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what is milk "curds", what has precipipated out? |
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casein |
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Which is the most abundant protein in the human body |
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collagen |
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Protein found in nails and hoofs and hair |
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keratin |
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Bacteria in milk can convert the lactose into what compound |
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lactic acid |
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Enzyme found in tears and saliva that kills invading bacteria |
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lysozyme |
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