Gastrointestinal System Vet. Anatomy and Physiology – Flashcards

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Parasympathetic Nervous System
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Includes nerves that emerge from the CNS as cranial nerves and nerves in the caudal portion of the spinal cord Includes the vagus nerve Effects are associated with the neurotransmitter acetylcholine Cholinergic Drugs
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Stimulation of PNS
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Decreases the heart rate Constricts the pupils Increases digestive secretions Improves blood flow to the GI tract Increases GI smooth muscle tone and motility Net Effect = Increased digestion and absorption The Rest and Restore System
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Sympathetic Nervous System
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Antagonizes or opposes the effects of the parasympathetic nervous system Neurotransmitter - Norepinephrine Nerves emerge from the spinal cord at the thoracic and lumbar segments of the spinal column Anticholinergic Drugs
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Stimulation of the SNS
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Increases heart rate Elevates blood pressure Redirects blood flow from nonessential to essential organs and skeletal muscle Fight or Flight System
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Ruminant
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has mixing and fermentation compartments called a forestomach which consists of the rumen, reticulum, and omasum and also has a true stomach called the abomasum
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Gastric
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refers to the stomach
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Enteric
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refers to the small intestine
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Colonic
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refers to the colon
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Prehension
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grasping food with the lips or teeth
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Mastication (Mechanical digestion)
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the mechanical grinding and breaking down of food (chewing)
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Layers of the wall of the GI tract
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Mucosa, Submucosa, Muscle, Serosa, Mesentery
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Mucosa
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the lining layer; consists of the lining epithelium and some loose connective tissue
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Submucosa
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between the mucosa and the thick muscle layer; contains glands (if present) and dense connective tissue
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Serosa
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outermost layer of thin, tough layer of connective tissue
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Mesentery
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sheets of connective tissue that suspend the GI tract from the dorsal body wall; contains blood and lymph vessels, and nerves
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Stratified squamous epithelium
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thick and tough; lines the mouth, pharynx, esophagus, and anus
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Simple columnar epithelium
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thin (allows for nutrient absorption); lines the stomach, small intestine, large intestine
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Skeletal muscle
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under voluntary control; present in the mouth, pharynx, cranial part of the esophagus, and the external anal sphincter
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Smooth muscle
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under involuntary control; present in the rest of the esophagus, stomach, small intestine, large intestine, and internal anal sphincter
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Circular muscle fibers
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narrow a section of the tube when they contract
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Longitudinal muscle fibers
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shortens a section of the tube when they contract
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Peristaltic Contractions
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Propel contents along the GI tract; consist of circular muscle contractions that move along the tract like waves, propelling contents along the tube ahead of them
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Segmental Contractions
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Back-and-forth mixing movements of intestinal contents; periodic, circular muscle contractions that occur in different adjacent sites; aid in digestion and absorption
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Soft palate
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soft mucosal flap that extends caudally from the hard palate on the roof of the mouth; divides the pharynx into the oropharynx and nasopharynx
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Oropharynx
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the opening at the back of the throat through which food and air both pass
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Hard palate
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bony roof of the mouth
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Parotid salivary glands
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located just ventral to the ear canals
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Mandibular salivary glands
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located ventral to the parotid glands at the caudal angle of the mandible
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Sublingual salivary glands
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located medial to the shafts of the mandible just under the base of the tongue
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Occlusal surface
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the surface on which the teeth come together
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Lingual surface
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"inner" surface of the teeth of the lower arcade
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Palatal surface
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surface of the teeth "facing" the hard palate
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Labial surface
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"outer-facing" surface of the teeth on the upper and lower arcade at the rostral end of the mouth
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Buccal surface
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"outer-facing" surface of the teeth more caudal in the mouth
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Dental Pad
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A flat, thick, connective-tissue structure on the maxilla opposite the lower incisors and canine teeth that ruminants have; in other words, ruminants do not have any upper incisors or canine teeth
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Dental Formula
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First number after the letter is the number of teeth in half of the upper arcade. This number is followed by a slash. The second number is the number of teeth in half of the lower arcade
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Crown
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the enamel covered, exposed part of a tooth
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Root
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the unexposed part of a tooth
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Gingiva
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the epithelial tissue that composes the "gums"
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Enamel
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outer coating of the crown of a tooth; the hardest tissue of the body
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Infundibulum
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a folding in the equine tooth that is a deep invagination of enamel
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Apex
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the tip of the tooth root where the blood and nerve supply enters the tooth
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Pulp
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the lattice-like material in the center of the tooth, which contains the nerve and blood supply
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Dentin
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the layer surrounding the tooth pulp; more dense than bone, but not as dense as the overlying enamel; makes up most of the tooth
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Cementum
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the hard connective tissue that covers the root of a tooth and helps secure it in its bony socket
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Digestive enzymes
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Proteins that promote the chemical reactions that split complex food molecules into simpler compounds; usually end in the suffix -ase
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Amylase
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an enzyme found in the saliva of omnivores but absent in carnivores; breaks down amylose, a sugar component of starch
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Lipase
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an enzyme found in the saliva of some young animals while they are nursing or are on a high-milk diet; breaks down lipids (fats)
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Salivary glands
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Under autonomic nervous system control Parasympathetic nervous system stimulation results in increased salivation Sympathetic nervous system stimulation results in "dry mouth"
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Esophagus
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A muscular tube that extends from the pharynx (throat to the stomach) that transfers swallowed material to the stomach (no digestion or absorption takes place here)
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Esophagus makeup
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Enters the stomach at the cardia which is surrounded by a weak sphincter (cardiac sphincter) which is capable of closing off the opening, enters the stomach at an angle, when the stomach becomes full, the stomach folds against the esophagus acting as a natural valve closing the end of the esophagus to prevent reflux This closure is so strong in the horse and the rabbit that they are incapable of vomiting
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Monogastric Stomach
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Cardia, Fundus, Body, Pyloric antrum, Pylorus
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Cardia
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area immediately surrounding the opening from the esophagus into the stomach
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Fundus
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forms a distensible, blind pouch that expands as more food is swallowed
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Body
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distensible section in the middle of the stomach
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Pyloric antrum
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distal part of the stomach that grinds up swallowed food
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Pylorus
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muscular sphincter that regulates the movement of chyme (digested stomach contents) from the stomach into the duodenum; prevents backflow of duodenal contents into the stomach
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Rugae
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multiple, long folds in the stomach
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Gastric Motility
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Food is ingested then fundus and body relax due to stimulation of the parasympathetic nervous system through the vagus nerve, body contracts to mix food antrum increases contractions (grinding), food moves towards pylorus chyme (liquified food) moves into the duodenum
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Parietal cells
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produce hydrochloric acid
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Chief cells
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produce pepsinogen (a precursor for the proteolytic (protein-digesting) enzyme pepsin)
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Mucous cells
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produce mucus, which contains mucins produced by goblet cells, that coats and protects the stomach (bicarbonate ions are also secreted which neutralize hydrochloric acid)
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G cells
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secrete gastrin
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Gastrin
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Release is stimulated by the presence of proteins (food) in the stomachStimulates parietal cells to produce hydrochloric acid Inhibits muscular activity by the fundus causing it to relax so that more food can be stored
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Histamine
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normally released by basophils and mast cells during inflammation or allergic reactions
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Enterogastric reflex
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prevents the stomach from pushing its contents into the duodenum before the small intestine is able to handle more chyme
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Secretin
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a hormone released from the duodenum in response to excess stomach acid being present in the small intestine - causes the stomach to relax - inhibits peristalsis of the body and antrum to slow gastric emptying
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Cholecystokinin (CCK)
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a hormone that decreases contractions of the antrum, body, and fundus and slows gastric emptying; released when large amounts of fat or protein are in the duodenum
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Reticulum
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Smallest forestomachSeparated from the rumen by the ruminoreticular fold - food moves freely between the reticulum and the rumen Lining is honeycomb shaped
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Rumen
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Large, fermentative vat Largest forestomach A series of muscular sacs partially separated by pillars (muscular folds)
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Ruminoreticular contractions
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occur 2 times per minutes and mix the contents of the stomach (Rumen)
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Fermentative digestion
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Bacteria and protozoa produce enzymes that break down feed Proteases break down protein into peptides Peptides are incorporated into the protein structure of microbes or ammonia and volatile fatty acids (VFAs) (provide energy) Cellulase breaks down cellulose and pectin in the cell walls in plants into monosaccharides (e.g. glucose) and polysaccharides
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Omasum
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Feed enters here from the rumen contains parallel, longitudinal muscular folds (leaves) further breaks down feed particles, dehydrates them, and moves them into the abomasum
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Abomasum
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true stomach
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Duodenum
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first section; leaves the stomach
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Jejunum
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middle section; where most absorption of nutrients occurs; longest part
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Ileum
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last section; enters the colon
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Ileocecal sphincter
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regulates movement of material into the colon or cecum
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Crypts
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are invaginations between the villi that produce new villus cells (old cells are shed)
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Secretory Diarrhea
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Secretion of intestinal fluids into the lumen occurs at a rate that cannot be compensated by absorption of the fluid from the bowel (e.g., Transmissible gastroenteritis in swine, parvovirus in dogs)
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Exudative Diarrhea
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Increased permeability of the intestinal mucosa from inflammation or infection results in protein, fluid, serum, and even blood lost in the intestinal lumen
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Maldigestion or malabsorption
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More fluid remains in the intestinal lumen because of the osmotic force the undigested food material has to hold fluid in the gut
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Decreased transit time
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Intestinal contents move through too quickly for the fluid to be absorbed
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Carbohydrate Digestion
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Amylase converts starch into small sugar segments called disaccharides which are further broken down into monosaccharides by other enzymes
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Protein Digestion
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Proteins are broken down by proteases into amino acids or dipeptides (two amino acids linked together)
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Emulsification
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the process by which fat globules are broken down
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Cecum, colon, and rectum
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Recovers fluids and electrolytes and stores feces until they can be eliminated
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Cecum
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(a blind sac that consists of a base, body, and apex; comma shaped; occupies the right side of the abdomen) - has longitudinal bands that separate the structure into haustra (sacculations of the colon and cecum)
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Ventral colon
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has longitudinal bands
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Sternal flexure
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between the left and right halves
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Dorsal colon
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has longitudinal bands, Diaphragmatic flexure - between the left and right halves
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hindgut fermenters
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Guinea pig, rabbits, rats, swine, horse
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Rectum
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Terminal portion of the large intestine, Contains stretch receptors that signal the defecation response when full
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Anus
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Internal (involuntary control) and external sphincters (voluntary control) control passage of fecal material
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Tenesmus
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straining to defecate from colonic or rectal inflammation and irritation
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Liver
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Largest gland in the body, Divided into hepatic lobes which are further, divided into hepatic lobules, filters materials absorbed from the gut, Receives its blood supply from the hepatic artery and the portal vein, Blood leaves the liver from the hepatic vein
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Bile
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Produced by the liver and contains bile acids, cholesterol, and bilirubin, Secreted into small canaliculi that merge to form bile ducts, which form the hepatic duct which combines with the cystic duct that leads to the gallbladder where bile is stored Horses do not have a gallbladder
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Albumin
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a protein made by the liver that plays an important role in maintaining the osmotic fluid balance between capillaries (blood) and tissues; a lack of albumin results in movement of fluid from the capillaries into the tissues, producing edema and fluid accumulation in body cavities (ascites)
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Glycogenolysis
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is the process by which glycogen is broken down into glucose for energy
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Gluconeogenesis
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a process in which glucose is made in the liver from amino acids
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