Final Prep New Stuff – Flashcards

Unlock all answers in this set

Unlock answers
question
When cyclobutene is burned in the presence of oxygen, what are the products?
answer
"CO2 and H20"
question
"An unknown compound may be heptane, 3-mehtylcyclohexene, or 2-heptene. If the red color of a bromine solution dissapears when it is added, the unknown may be: "
answer
"2-heptene or 3-methylcyclohexene"
question
"The hydrogenation of an alkene gives"
answer
"An alkane"
question
Metabolism
answer
all chemical reactions that provide energy & substances required for cell growth
question
What are the two types of metabolism?
answer
Catabolism and anabolism
question
Catabolism
answer
Breaks down large molecules into smaller ones. Releases energy.
question
Anabolism
answer
Builds large molecules out of small ones
question
What stage of metabolism involves the digestion of polysaccharides? (pp 22.1)
answer
glycolysis
question
What is meant by a catabolic reaction in metabolism? (pp 22.2)
answer
That large molecules will be broken down into smaller ones. (As in food digestion)
question
What is ATP composed of?
answer
the nitrogen base adenine, a ribose sugar, and 3 phosphate groups
question
What is ATP composed of?
answer
an adenine base, ribose sugar, and 3 phosphate groups
question
What is the role of ATP in the body?
answer
Provides energy
question
What is a coupled reaction? (What two kinds of reactions make one up?)
answer
A combination of an energy-requiring reaction with an energy-producing one
question
Why is ATP considered a high-energy comppund? (pp 22.7)
answer
Because it produces 7.3 kcal/mol of energy when hydrolyzed
question
What reaction does NADH+ participate in?
And what type of bonds does it form?
answer
Oxidation reactions, forms carbon/oxygen double bonds
question
What happens in an oxidation reaction?
answer
A loss of Hydrogen/electrons. Caused by addition of oxygen
question
What occurs in a reduction reaction?
answer
A gain of hydrogen/electrons. Oxygen is lost.
question
What vitamin component does NAD+ contain?
answer
niacin
question
What is the function of NAD+ as a coenzyme? (Does it undergo oxid or red reactions and what does it produce?)
answer
Oxidizes to produce carbon/oxygen double bonds
question
What vitamin component does FAD contain?
answer
riboflavin (vitamin B)
question
What does NAD+ oxidize to?
answer
NADH
question
What is FAD's function as a coenzyme?
answer
Accepts Hydrogen from other molecules, produces Carbon/carbon double bonds (C=C)
question
What does FAD reduce to?
answer
FADH2
question
what vitamin does CoA contain?
answer
pantothenic acid (vitamin B3)
question
What is CoA's function as a coenzyme
answer
Activates acyl groups to produce thioesters
question
Why are thioester bonds important?
answer
They are energy-rich
question
What coenzyme (NAD, FAD, CoA) creates carbon/carbon double bonds?
answer
FAD
question
What is the general reaction that occurs during carbohydrate reaction? (pp 22.17)
answer
hydrolysis
question
What are the functional units of lactose?
answer
Galactose and glucose
question
What are the monosaccharides that make up sucrose?
answer
fructose and glucose
question
what are the functional units of maltose?
answer
glucose and glucose
question
What is the starting molecule of glycolysis?
answer
glucose
question
what are the products of glycolysis?
answer
2 ATP

2 pyruvate

2 NADH

question
How many carbons does pyruvate contain?
answer
3
question
What are the two stages of glycolysis?
answer

"Energy investing phase" (AKA the part where 2 ATPs are used to make sugar phosphates)

"The energy generating phase" (AKA hydrolysis of sugar phosphates to produce 2 pyruvates, 2 ATP, and 2 NADH.

question
What happens in "Stage 1" of glycolysis
answer
2 ATPs are used to attach phosphate groups to glucose, creating sugar phosphates.
question
What happens in "Stage 2" of glycolysis?
answer
The sugar phosphates produced in stage one undergo a series of hydrolysis reactions to produce 2 pyruvates, 2 ATPs, and 2 NADH molecules.
question
What are the three possible pyruvate pathways?
answer
Fermentation, Lactate production, acetyl CoA production
question
Which of the pyruvate pathways occur under anaerobic conditions?
answer
Fermentation and Lactate production
question
Which of the pyruvate pathways occur under aerobic conditions?
answer
Acetyl CoA production
question
What are the products of fermentation?
answer
ethanol and CO2
question
What occurs during lactate production?
answer
pyruvate remains in the cytoplasm and is reduced to lactate.
question
What is the role of NAD+ in lactate production?
answer
It is used to oxidize glyceraldehyde to produce a small amount of ATP
question
What occurs in acetyl CoA production?
answer
pyruvate moves from the cytoplasm to the matrix to be oxidized.Carbon is removed from pyruvate as CO2, and acetyl CoA is the product
question
Three enzymes that 'officially' regulate glycolysis
answer
Hexokinase, phosphofructokinase, pyruvate kinase
question
Under what conditions is glucagon secreted?
answer
When blood sugar is low
question
what is glucagon's effect on glycolysis, and why?
answer
it inhibits glycolysis, because glycolysis reactions use glucose, and since blood sugar is low when glucagon is secreted, more glucose shouldn't be taken away.
question
What is glucagon's effect on gluconeogenesis, and why?
answer
activates, because gluconeogenesis creates glucose, which is needed when glucagon is secreted.
question
What is glucagon's effect on glycogenolysis and why?
answer
activates glycogenolysis, because glycogenolysis breaks down stored glycogen to help restore blood glucose levels
question
What effect does glucagon have on glycogenesis, and why?
answer
It inhibits it, because glycogenesis pulls glucose out of the bloodstream to start its reactions.
question
Under what conditions is insulin secreted?
answer
When blood sugar is high
question
what effect does insulin have on glycolysis, and why?
answer
It activates it, because glycolysis stimulates the breakdown of glucose to produce energy
question
What effect does insulin have on gluconeogenesis and why?
answer
It inhibits it, because gluconeogenesis FORMS glucose, and if insulin is being secreted, blood glucose is already high
question
What is insulin's effect on glycogenolysis, and why?
answer
inhibits it, because glycogenolysis stimulates the hydrolysis of glycogen to form glucose.
question
what is insulin's effect on
answer
question
Which part of the cell does the Cori cycle occur?
answer
????
question
Can secondary alcohols be oxidized? If so, what are the products?
answer
Yes, to ketones
question
Can primary alcohols be oxidized? If so, what is the product(s)?
answer
Yes, aldehydes to carboxylic acids
question
Can tertiary alcohols be oxidized? If so, what is the product(s)?
answer
No
question
What is a primary alcohol?
answer
the the carbon that the -OH is attached to is attached to only one other thing
question
what is a secondary alcohol?
answer
when the carbon that the -OH is attached to is attached to two other things (alkyl groups)
question
What is a tertiary alcohol?
answer
When the carbon carrying the -OH group is attached to three other alkyl groups
question
What is the product of the hydration of 1-pentene?
answer
a secondary alcohol
question
What carboxylic acid and amine are used to make acetaminophen?
answer
ethanoic acid and 4-hydroanaline
question
What is the difference between an ester and and ether?
answer
An ether doesn't contain an alcohol, and an ester does.
question
In the presence of an (alkane or alkene), the red color of a Bromine solution disappears.
answer
alkenes
question
Parathon binds to the active site of an enzyme. What is it?
answer
irreversible inhibitor
question
what is a cofactor that is a small organic molecule?
answer
coenzyme
question
What is the difference between an aldehyde and a ketone?
answer
aldehydes have the double bonded oxygen at the end of the chain, ketones have it inside the chain
question
which RNA covalently attaches to amino acids?
answer
tRNA
question
the products from the saponification of a triacylgylcerol would be
answer
glycerol and fatty acid salts
question
What kinda of side chains create salt bridges?
answer
acidic and a basic
question
what is the basic structure of an amino acid?
answer
H2N-CH(R)-C(=O)-OH
question
Glycogenesis (def)
answer
Synthesis of glycogen from glucose
question
When does glycogenesis occur?
answer
When blood glucose(blood sugar) is high.
question
What is the enzyme that drives glycogenesis?
answer
glycogen synthase
question
What is glycogenolysis?
answer
The breakdown of glycogen to glucose
question
What is the main enzyme that drives glycogenolysis?
answer
glycogen phosphorylate
question
When does glycogenolysis occur?
answer
when blood sugar is low/during strenuous exercise
question
What is gluconeogenesis?
answer
production of glucose from carbons retrieved from amino acids, lactates, and glycerol.
question
Where does gluconeogenesis occur?
answer
The liver
question
What is the role of gluconeogenesis and why?
answer
source of glucose after glycogen stores are depeleted, usually during fasting or really heavy exercise.
question
What are the starting molecules of gluconeogenesis?
answer
2 Pyruvates and lactate
question
What is the energy requirement of gluconeogenesis?
answer
4ATP, 4GTP, and 2NADH
question
What are bypass reactions and why do they occur?
answer
Bypass reactions make gluconeogenesis 'energetically favorable' by skipping over the 3 energy-requiring reactions that normally occur during glycolysis
question
What are the 3 energy-requiring reactions during glycolysis?
answer
Reactions 1, 3, and 10
question
What are the hormones that drive the 3 energy-requiring reactions in glycolysis?
answer

hexokinase (reaction 1)

phosphofructokinase (reaction 3)

pyruvate kinase (reaction 10)

question
what effect does insulin production have on glycogenesis and why?
answer
activates it, because glycogenesis takes glucose out of the bloodstream and stores it as glycogen.
question
Cori cycle and when it occurs
answer
controls the flow of lactate and glucose between muscles and liver to prevent lactate buildup in muscle. Most active after strenuous exercise
question
Citric Acid Cycle (def)
answer
degrades acetyl CoA to yield CO2 and energy to produce NADH+H and FADH2 needed for ATP production in metabolism
question
Where does the Citric Acid Cycle occur?
answer
Matrix of the mitochondria
question
What are the products of the Citric Acid Cycle?
answer
3 NADH, 1FADH2, 1GTP
question
How much ATP is produced per Citric Acid Cycle?
answer
12
question
Acteyl CoA as entry molecule
answer
acetyl group from Acetyl CoA bonds to (some thing) to make HS-CoA
question
Where does oxidative phosphorylation occur?
answer
Inner membrane of mitochondria
question
Where do NADH and FADH2 originate from?
answer
Matrix of mitochondria
question
What is the final e- acceptor in the e- transport chain?
answer
Oxygen (from water)
question
What are the e- carriers? (4)
answer
FMN, FeS clusters, Coenzyme Q, cytochrome
question
What complexes undergo proton pumping?
answer
Complexes I, III, IV
question
Chemeosmotic model (what and by who)
answer
Peter Mitchell's model which explains proton pumping and how the proton concentration gradient in the intermembrane space of the mitochondria than in the matrix, creating a concentration gradient. H+ will tavel down the gradient to the matrix, where it helps ATP production
question
Why is ATP synthase dependent on H+ produced by e- transport chain?
answer
because it provides energy to make ATP
question
How much ATP is produced per NADH
answer
3 ATPs
question
How much ATP is produced per FADH2?
answer
2 ATPs
question
How much ATP is produced from glycolysis?
answer
6 ATP
(-2 used to activate, +6 for oxidation, -2 for NADH transport, and +4 from phosphorylation)
question
how much ATP is produced from pyruvate?
answer
6 ATPs
question
How many ATPs are produced from ONE Citric acid cycle?
answer
12
question
how many citric acid cycles occer per glucose molecule?
answer
2 (means 24 ATPs produced from CAC for one glucose)
question
How much ATP does it take to transport NADH to e- chain?
answer
-2 ATPs
question
How are triacylgylerols digested?
answer
They are initially broken down through emulsification by bile salts in small intestine. Then micelles (emulsified triacylglycerols) are hydrolyzed (by pancratic lipase) and are broken down into monoacylglycerols and free fatty acids. These are absorbed into intestinal lining, where they reform and are coated with proteins, creating chylomicrons which are released into bloodstream.
question
what happens to chylomicrons once they reach the cells?
answer
They are hydrolyzed into glycerol and free fatty acids and used for energy production
question
Where are triacylglycerols stored?
answer
adipose tissue
question
fat mobilization
answer
breaks down stored triacylglycerols into fatty acids and glycerol
question
Three steps of fatty acid breakdown
answer

Activation: Coenzyme A, energy required

Transport: by carnitine

Β-oxidation: products of 1 cycle

question
how do you calculate how many acetyl CoAs are produced from a given fatty acid?
answer
take number of carbons in fatty acid chain, and divide by 2
question
how do you calculate the number of cycles needed to breakdown a given fatty acid?
answer
take how many carbons are in chain, divide by 2, subract 1
Get an explanation on any task
Get unstuck with the help of our AI assistant in seconds
New