Epidemiology Test One Review – Flashcards
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1) How many cases do you need to represent an epidemic?
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"The occurrence in a community or region of cases of an illness, specific health-related behavior, or other health related events clearly in excess of normal expectancy." The "normal expectancy" is six cases per year
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2) Know the definition of a Pandemic
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defined as "an epidemic occurring worldwide, or over a very wide area, crossing international boundaries, and usually affecting a large number of people."
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3) Know the definition of "a Population"
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"all the inhabitants of a given country or area considered together .... "
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4) Alexander Fleming is best known throughout history as...........
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( 1881-1955) discovered the antimicrobial properties of the mold Penicillium notatum in 1928. This breakthrough led to development of the antibiotic penicillin, which became available toward the end of World War II.
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5) Who was the first to employ quantitate methods to describe population vital statistics?
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John Graunt
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6) Epidemiology is an observational science that capitalizes on...................
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naturally occurring situations in order to study the occurrence of disease.
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7) How far back does the history of epidemiology go?
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The history of epidemiology originated as early as classical antiquity (before about 500 AD), and later during the medieval period was marked by bubonic plague epidemics in Europe.
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8) What disease does Yersinia pestis cause?
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The Black Plague
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9) Before familiar with the Tuskegee Study. Know the ethical issues with this research project.
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Tuskegee study was an infamous clinical study conducted between 1932 and 1972 by the U.S. Public Health Service to study the natural progression of untreated syphilis in rural African-American men in Alabama. They were told that they were receiving free health care from the U.S. government. None of the men infected were ever told they had the disease, nor were any treated for it with penicillin after this antibiotic became proven for treatment. (It is extremely unethical to watch patients suffer and document without helping them when you have the cure. Especially to not tell them they have the disease.)
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10) What does the term epidemiologic transition mean? Be able to provide an example.
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describes a shift in the patterns of morbidity and mortality from causes related primarily to infectious and communicable diseases to causes associated with chronic, degenerative diseases. At present, the United States is in the post transition stage, which is dominated by diseases associated with personal behavior, adverse lifestyle, and emerging infections.
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11) Any factor that brings about change in a health condition or defined characteristic is known as a .....................
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Determinant
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12) What is risk assessment according to your author?
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Epidemiologic studies provide quantitative measurements risks to health through a methodology Risk assesment use: estimate individuals' risks of disease, accident, or defect
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13) Be familiar with Koch's Postulates
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Four postulates to demonstrate the association between a microorganism and a disease were formatted as follows: I. The organism must be observed in every case of the disease. 2. It must be isolated and grown in pure culture. 3. The pure culture must, when inoculated into a susceptible animal, reproduce the disease. 4. The organism must be observed in, and recovered from, the experimental animal
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14) Know the Key Characteristics of epidemiology?
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Population Focus, Distribution, Determinants, Outcomes, Quantification, Control of Health Problems
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15) Know the relationship between incidence and prevalence?
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Incidence refers to the occurrence of new disease or mortality within a defined period of observation (e.g., a week, month, year, or other time period) in a specified population. Prevalence refers to the number of existing cases of a disease or health condition, or deaths in a population at some designated time.
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16) What does lifetime prevalence mean?
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denotes cases diagnosed at any time during the person's lifetime.
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17) Be familiar with Bar, Line, and pie charts. Be able to recognize which types of data sets are most appropriate for each?
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Pie charts - percentages or ratios. Proportion of cases according to several catagories Line chart- Detect trends in the data Bar Chart- shows the frequency of cases for categories of a categorical (variable). Height represents the frequency. Along base are categories of the variables
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18) Know one of the first steps in presenting data after they have been reviewed for accuracy and completeness.
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Counting and tabulating cases is one of the fi rst steps in presenting data after they have been reviewed for accuracy and completeness (a process called data cleaning).
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19) Which of the following are ratios? Time, Rate, Percentage, and proportion?
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Rate, proportion, and percentage are all types of ratios
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20) What are epidemiology measures? What type of information do they provide?
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morbidity (illness) and mortality (death): crude rates, death rates, case fatality rates, and cause-specific rates. crude rates - a type of rate that has not been modified to take account of any of the factors such as demographic makeup of the population that may affect the observable rate. summary rates based on the actual number of events in a population over a given time period death rates- case fatality rates - Number of deaths due to a disease among persons that are affected with the disease cause specific rates - mortality divided by the population size at the midpoint of a time period times a multiplier
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21) Be able to define incidence, prevalent, population at risk as well as immune fraction.
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incidence: the occurrence of a new disease or mortality within a defined period of observation such as a week or a month in a specific population Prevalence:the number of existing cases of a disease or health condition, or deaths in a population at some designated time Population at risk: members of the population who are capable of developing the disease of condition being studied Immune fraction - (later in the book it talk about immune status and says:) at lowered risk of developing the infection, although they may be susceptible in some situations, for example, if they receive large doses of an infectious agent or they are under treatment with immunosuppressive drugs.
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22) What happens to the prevalence of a disease as the incidence rate increases?
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the prevalence of the disease increases
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23) What happens to prevalence as cure rates increase and incidence rates decline?
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It goes down.
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24) Be able to recognize and define case fatality rates
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refers to the number of deaths due to a disease that occur among persons who arc afflicted with that disease. CFR=Number of deaths due to disease "X"/ Number of cases of disease "X" * 100 during a time period
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25) What is external validity? What does it allow us to do with our findings in an epidemiological study?
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The term representativeness (also known as external validity) refers to the generalizability of the findings to the population from which the data have been ta ken.
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26) Know who by law must report cases of certain diseases deemed as reportable.
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Physicians and other health care providers must report certain diseases to health authorities
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27) Know what a registry is. What importance do they hold for epidemiology?
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is a centralized database for collection of information about a disease.
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28) Be able to provide an example of a reportable disease.... Polio, HIV, Measles..........
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The diseases are usually infectious and communicable ones that might endanger a population; examples are the sexually transmitted diseases, rubella, tetanus, measles, plague, and food borne disease.
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29) Is epidemiology a quantitative or qualitative discipline?
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Epidemiology is a quantitative discipline that requires data for descriptive and analytic studies.
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30) What is primary data? What is secondary data?
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primary is data you gather yourself secondary is information gathered by outside source.
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31) What is the BRFSS? What type of data does it collect?
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The Behavioral Risk Factor Surveillance System (BRFSS) is a noteworthy program used by the United States to monitor at the state level behavioral risk factors that are associated with chronic diseases. That should be primary data
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32) What type of data does the Vital Statistics Cooperative Program collect?
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National Vital Statistics System [Refer to Table 3-6 for information about the Vital Statistics Cooperative Program, which partially supports state costs for collecting vital statistics.] • Birth Data • Mortality Data • Fetal Death Data • Linked Births/ Infant Deaths • National Mortality Followback Survey • National Maternal and Infant Health Survey • Vital Statistics Data Available Online
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33) Know what a vital event is. Be able to give an example.
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Deaths, births, marriages, divorces, and fetal deaths.
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34) What is public health surveillance? What type of data does it collect?
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Refers to the systematic and continuous gathering of information about the occurrence of diseases and other health phenomena.
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35) True or False....Registries collect data over time. Monitoring cancer trends would be an example???
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registry is a centralized database for collection of information about a disease. The National Program of Cancer Registries (NPCR)administered by CDC, United States This program" ... collects data on the occurrence of cancer; the type, extent, and location of the cancer; and the type of initial treatment." The purposes of the state registries are to: • "Monitor cancer trends over time. I would say that registries collect data over time is a true statement
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36) If you were HIV positive and died of pneumonia would your death certificate contain your HIV status?
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Information from death certificates regarding cancer as the underlying cause of death is believed to be more accurate than the information for other diagnoses such as those for nonmalignant condition. However, assignment of the cause of death sometimes may be arbitrary. In illustration, diabetes may not be given as the immediate cause of death; rather, the certificate may list the cause of death as heart failure or pneumonia, which could be complications of diabetes. Yet another problem is the stigma associated with certain diseases. For example, if the decedent died as a result of AIDS or alcoholism and was a long-time friend of the attending physician, the physician may be reluctant to specify this information on a document that is available to the general public.
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37) Be able to recognize the purpose of descriptive epidemiology.
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1. permit evaluation of trends in health and disease 2. provide a basis for planning, provision, and evaluation of health services 3. identify problems to be studied by analytic methods and suggest areas that may be fruitful for investigation Descriptive epidemiology classifies the occurrence of disease according to the variables of person (who is affected), place (where the condition occurs), and time (when and over what time period the condition has occurred).
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38) What do cross-sectional studies measure?
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This type of investigation is defined as one " . . . that examines the relationship between diseases (or other health-related characteristics) and other variables of interest as they exist in a defined population at one particular time. The presence or absence of disease and the presence or absence of the other variables . . . are determined in each member of the study population or in a representative sample at one particular time.'"1
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39) Be familiar with the changes in causes of death as one ages.
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car accident for teens and younger and heart attack for older population.
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40) How does SES affect causes of death?
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Additionally, low income and education have been shown to be strong predictors of a range of physical and mental health problems, including respiratory viruses, arthritis, coronary disease, and schizophrenia. These may be due to environmental conditions in their workplace, or, in the case of mental illnesses, may be the entire cause of that person's social predicament to begin with.[2][3][4] Education in higher socioeconomic families is typically stressed as much more important, both within the household as well as the local community. In poorer areas, where food and safety are priority, education can take a backseat. Youth audiences are particularly at risk for many health and social problems in the United States, such as unwanted pregnancies, drug abuse, and obesity.[5]
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41) Be able to recognize several person variables as they relate to epidemiology.
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Examples of person variables are demographic characteristics such as: sex, age, and race/ethnicity, the mother's age, education , marital status, and socioeconomic status (as measured by income-to-poverty ratio). A place variable (location of residence of mother), nativity (place of origin), migration, and religion.
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42) What is the leading type of cancer for both males and females?
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The cancer diagnoses with the highest incidence rates per 100,000 are prostate cancer for males ( 150.0 per 100,000) and breast cancer for females (1 19.0 per 100,000). For both males and females, cancer of the lung and bronchus are the leading cause of cancer mortality.
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43) Be able to identify the several factors used to determine SES
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person's income level, education level, type of occupation
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44) What are health disparities?
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which refers to differences in the occurrence of diseases and adverse health conditions in the population.
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45) Be able to identify several place variables.
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Morbidity and mortality vary greatly with respect to place (geographic regions that are being compared). Examples of comparisons according lo place are international, national (within-country variations such as regional and urban-rural comparisons), and localized occurrences of disease. geographic region International- infectious and communicable disease malnutrition infant mortality suicide climate cultural factors dietary habits access to healthcare National climate latitude environmental pollution geographic region (north, south, east, west) state/county Urban-Rural person to person contact crowding inner city poverty agriculture (toxic pesticides, unintentional injuries) Localized pattern specific environmental that may exist in a particular geographical location radon gas/ lung cancer vectors that may not survive other places
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46) Know how person to person and crowding affect communicable disease rates.
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Urban diseases and causes of mortality are more likely to be those spread by person -to-person contact, crowding, and inner-city poverty or associated with urban pollution.
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47) Know what are cyclic and secular trends are.
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Cyclic trends are increases and decreases in the frequency of a disease or other phenomenon over a period of several years or within a year. Secular trends refer to gradual changes in the frequency of diseases over long time periods.
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48) What is clustering?
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Refers to "a closely grouped series of events or cases of a disease or other health -related phenomena with well-defined distribution patterns in relation to time or place or both.
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49) Be able to identify the source of authority for many of the interventional strategies used in epidemiology and public health.
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Preamble to the constitution. "Common defense and general welfare" give epi its legal authority Article 1 Section B of US constitution gives congress the right to impose taxes and gives CDC & Public health service right to protect.
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50) What is shoe leather epidemiology?
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doing the literal leg work of epi. LIke Snow walking from door to door asking about their illnesses trying to figure it all out
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51) Know the three components of the epidemiology triangle.
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Agent, host, environment
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52) What is passive immunity?
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refers to immunity that is acquired from antibodies produced by another person or animal.
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53) What is an epidemiological Reservoir? Be able identify several possible reservoirs of disease.
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Another term to describe the presence of an infectious agent in the environment is a reservoir, which is a place where infectious agents normally live and multiply; the reservoir can be human beings, animals, insects, soils, or plants. Clostridium botulinum is soil, but the source of most botulism infections is improperly canned food containing C. botulinum spores. Humans reservoir- sexually transmitted diseases, measles, mumps, streptococcal infection, and many respiratory pathogens. animals:Long recognized zoonotic diseases include brucellosis (cows and pigs), anthrax (sheep), plague (rodents), trichinellosis/trichinosis (swine), tularemia (rabbits), and rabies (bats, raccoons, dogs, and other mammals). Zoonoses newly emergent in North America include West Nile encephalitis (birds), and monkeypox (prairie dogs) environment: Many fungal agents, such as those that cause histoplasmosis, live and multiply in the soil. Outbreaks of Legionnaires disease are often traced to water supplies in cooling towers and evaporative condensers, reservoirs for the causative organism Legionella pneumophila.
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54) What is an infection?-page 138
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"an illness due to a specific infectious agent o r its toxic products that arises the rough transmission of that agent or its products from an infected person, animal, or reservoir to a susceptible host, either directly or indirectly through an intermediate plant or animal host, vector, or the inanimate environment."
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55) What is virulence?
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refers to the severity of the disease produced, i.e., whether the disease has severe clinical manifestations or is fatal in a large number of cases.
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56) What do we mean by index case?
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is used in an epidemiological investigation of a disease outbreak to denote the first case of a disease to come to the attention of authorities.
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57) What is Herd immunity?
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Resistance of an entire community to an infectious disease due to the immunity of a large proportion of individuals in that community to the disease.
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58) Be able to recognize several portals of exit and entries
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portal of exit is the site from which the agent leaves that person's body; portals of exit include respiratory passages, the alimentary canal, the genitourinary system, and skin lesions. Entries or where the agent enters the body. Examples of portals of entry are the respiratory system (through inhalation), a skin wound (such as a break in skin), and the mucus membranes, which line some of the body's organs and cavities-e.g., nose, mouth, and lungs.
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59) What is a vector?
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is an animate, living insect or animal that is involved with the transmission of disease agents.
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60) What is a fomite?
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is an inanimate object that carries infectious disease agents; fomites include the classroom doorknob, used towels found in a locker room, or carelessly discarded tissues.
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61) What is one the simplest strategy to prevent foodborne illnesses?
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Foodborne illness can be prevented through the following procedures: • Thoroughly wash hands and surfaces where food is being prepared. • Avoid cross-contamination - e.g., keep juices from raw chicken and meats away from other foods. • Cook foods at correct temperatures that are sufficient to kill microorganisms, e.g., 180°F for poultry. • Use proper storage methods-i.e., in a refrigerator below 40 °F. (Don't let your lunch stay in a hot car without refrige ration.)
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62) What is a zoonotic disease?
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as diseases that can be transmitted from vertebrate animals to human beings.
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63) Why do we call the flu of 1918 the Spanish Flu?
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Pandemic influenza. Also known as the Spanish Flu, this pandemic raged from 1918 to 1919 and killed 50 to 100 million persons globally. Because our infected troops brought the flu to the front line in Spain where they all came down with the flu. It then spread worldwide because of the war.
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64) Where did the Spanish Flu originate?
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Fort Riley Kansas
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65) What ended the worldwide Spanish flu pandemic? Why did it end?
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Because there we no reservoirs left for it to inhabit. Everyone in the world had either died from the flu or lived through it.
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66) What animal is the Spanish Flu thought to have come from?
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Horse and Pig manure
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67) How can an incubation period help identify possible infectious agents?
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Certain diseases have certain incubation periods. So if we know the incubation period it can help us to determine or rule out certain diseases depending on their incubation period
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68) What is secondary sewage treatment? What is primary sewage treatment?
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Primary treatment involves basic processes to remove suspended solid waste and reduce its biochemical oxygen demand (BOD) - the amount of oxygen microorganisms must consume to breakdown the organic material present in the wastewater. This, in turn, increases dissolved oxygen, which is good for aquatic organisms and food webs. Primary treatment can reduce BOD by 20 to 30 percent and suspended solids by up to 60 percent. Secondary treatment uses biological processes to catch the dissolved organic matter missed in primary treatment. Microbes consume the organic matter as food, converting it to carbon dioxide, water, and energy. While secondary treatment technologies vary, the final phase of each involves an additional settling process to remove more suspended solids. Secondary treatment can remove up to 85 percent of BOD and total suspended solids
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69) What is an attack rate? Be able to calculate one
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An alternative form of the incidence rate that is used when the nature of a disease or condition is such that a population is observed for a short time period. The attack rate is calculated by the formula ill/(ill +well) X 100 (during a time period ). The attack rate is not a true rate because the time dimension is often uncertain
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70) Be able to identify reasons that some people are exposed and develop the condition while others share the same exposure and do not develop disease?
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age, immune system, dose relationship, faulty recall,
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71) What is the significance of Article 1 section 8 of the American Constitution?
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Gives congress authority to impose taxes to "provide for the general welfare of the United States and to regulate foreign commerce.
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72) What was the seminal case for the exercise of public health powers? What was the issue the court had to decide?
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Jacobson vs Massachusetts All citizens were to be vaccinated against smallpox. Jacobson said mandated vaccinations violated his religious freedom. Supreme court said he had to be vaccinated
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73) What does the Fifth Amendment guarantee?
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The Fifth Amendment guarantees the right to a grand jury, forbids "double jeopardy," and protects against self-incrimination. It also requires that "due process of law" be part of any proceeding that denies a citizen "life, liberty or property" and requires the government to compensate citizens when it takes private property for public use.
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74) True or False...in most cases the right to investigate is voluntary in nature and does not require an exercise of authority or power?
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True
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75) What does due process mean?
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Due process 1. is the legal requirement that the state must respect all legal rights that are owed to a person. 2. a fundamental principle of fairness in all legal matters, both civil and criminal, especially in the courts.
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76) Know the five legal considerations of epidemiological data collection.
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1. Protection of all records 2. special confidentially provisions for medical or other information 3. Required reporting of particular disease or conditions 4. Status of information in investigation files under the federal freedom of investigation act. 5. the applicability of federal or state human subjects research boards.
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77) Be familiar with the Freedom of Information Act. Be able to identify several exceptions concerning data confidentially.
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The Freedom of Information Act (FOIA) is a law that gives you the right to access information from the federal government. It is often described as the law that keeps citizens in the know about their government.