Bio Exam 4 – Flashcards
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_____ bind(s) to DNA enhancer regions.
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Activators
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Which of the following events in transcription occurs last?
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The mRNA is released from RNA polymerase.
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What is the function of the promoter site in transcription?
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It is the site at which RNA polymerase binds to start transcription.
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Which nucleic acid is translated to make a protein?
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mRNA
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At which site do new tRNAs enter the ribosome?
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First binding site in the ribosome (A site)
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True or false. A tRNA with an anticodon complementary to the stop codon catalyzes the reaction by which translation is terminated.
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False
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Which term describes a circular piece of bacterial DNA that is used in cloning?
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Plasmid
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Which of the following steps must be performed first when using recombinant DNA technology to produce a human protein in bacterial cells?
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The human gene is isolated from a human cell nucleus.
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True or false. The term "sticky ends" refers to the ends on DNA that are generated by restriction enzymes, which can base pair with any DNA molecules that contain complementary sticky ends.
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True
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Which of the following is LEAST likely to be a health problem for someone with cystic fibrosis?
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obesity
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The allele that causes cystic fibrosis is recessive. An individual who is heterozygous for cystic fibrosis
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is a carrier.
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If Sophie has a brother or sister from the same parents, what are the chances that sibling would have cystic fibrosis?
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25%
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If someone is a carrier of a recessive genetic disorder, it means he or she has __________ of the allele, and __________ exhibit symptoms of the disorder.
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one copy; does not
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Which of the following do you think contributed the most to the success of Rhys' gene therapy?
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Doctors were replacing only one gene, and they only had to insert that gene into bone marrow cells.
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Theoretically, which of the following diseases should be the easiest to treat through gene therapy, considering the targeted organs and tissues where the corrected gene must be delivered?
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diabetes, since the target cells are found only in the pancreas
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A codon of mRNA should be UUC, but a mutation changed the first nucleotide base of the original DNA template to a thymine (T). Which anticodon would bind to the mutated version of the codon?
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UAG
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What is a plasmid?
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circular extra-chromosomal DNA found in bacteria
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What process replaces defective human genes with normal, functional genes?
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gene therapy
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Which disease would be the most likely candidate for gene therapy?
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Hemophilia
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Why was golden rice engineered?
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To produce beta-carotene
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What happens right after a recombinant plasmid is made during the cloning process?
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The recombinant plasmid is reinserted into a bacterial cell.
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In some cells, which process may be affected by repressors that regulate the amount of gene product present?
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RNA transcription.
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Which types of organisms would be most useful as model organisms with which to compare human DNA?
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organisms from all kingdoms of life
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What ability of individual stem cells is described by the term totipotent?.
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To become any other somatic cell type
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Which of the following is the immediate ancestor of modern humans?
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Homo erectus
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Which of the following has been given the nickname "hobbit?"
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Homo floresiensis
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Which of the following is the first and least known of the Homo species?
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Homo habilis
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The famous skeleton "Lucy" was found where?
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Ethiopia
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Which of the following refers to the change in the characteristics in a population over time?
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the process of evolution
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What is the difference between a scientific theory and a popular theory?
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A scientific theory can explain all known evidence, whereas you can probably find evidence to dispute a popular theory.
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How is a biological population different from the population of a whole ecosystem, such as a rainforest?
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A biological population consists of all one species instead of many species.
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When Darwin referred to the Linnaean classification system, what did he suggest?
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All members of the same family have more in common than all members of the same order.
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Which members of the primate order have more ape-like characteristics?
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ancient hominins
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Which alternative to the theory of evolution proposes that today's living things evolved from multiple common ancestors?
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the hypothesis of separate types
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Which of the following anatomical features of the 3.2-million-year-old Australopithecus fossil known as "Lucy" suggest she was a bipedal hominid?
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a much shorter hip bone that is broader from front to back and wraps around the side
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How do scientists know that the hominid called "Ardi" is about 4.4 million years old?
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by using radiometric dating techniques on the volcanic deposits found above and below the layer containing Ardi
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Which organisms are most closely related?
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Cougar and lynx, which are both in the family Felidae
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How are a bat's wing, a sea lion's flipper, and a lion's front leg related?
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They are all homologous structures.
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What is biological evolution?
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the gene changes occurring in populations over many generations
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What is the process by which populations adapt to a changing environment
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natural selection
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Which explanation could be considered a Lamarckian argument?
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As giraffes stretched their necks to eat leaves, they passed this trait to their offspring and subsequent generations of giraffes developed long necks.
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What is meant by consilience, which supports the theory of common descent?
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Observations from many different sources support the theory.
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How do scientists determine the dates of fossils?
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measure the ratio of a radioactive element to the decay products
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Which human structure has a modification that allows for an upright stance?
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pelvis
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The Carolina chickadee, boreal chickadee, and black-capped chickadee are small songbirds that look and sound very similar to one another. What could account for their differences?
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Geographical separation
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Which hypothesis suggested that species arise separately and then adapt to a changing environment over time?
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transformation hypothesis
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In a species of snail, dark-shelled individuals are better hidden from bird predators in the shady forest, while light-shelled individuals are better hidden in well-lit brushy edge areas. If there were no areas of intermediate brightness in this habitat,which type of selection would act on shell color in these snails?
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Disruptive selection
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Small lizards have difficulty defending their territory, but large lizards are more likely to be preyed upon by owls. Which type of selection would act on body size in these lizards under these conditions?
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Stabilizing selection
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Has evolution by natural selection recently occurred in the worldwide populations of Mycobacterium tuberculosis?
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Yes, the frequency of the adaptive allele for drug resistance has increased over time.
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What is unique about deer mice?
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They are the most populous mouse found in North America.
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You wish to research how genetics determine color of deer mice. How many genes should you focus on?
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1
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The three-spine stickleback typically lacks armor in fresh water. Why?
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To allow for faster growth.
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In natural selection, what changes in a population over time?
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the frequency of an allele for a particular gene in a population
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What do alleles give rise to in a population?
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variation
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Which of the following is the best definition of adaptation?
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a trait favored by natural selection
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Why have public health officials once again become very concerned about tuberculosis in the 21st century?
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Antibiotic-resistant strains of tuberculosis are on the rise.
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How is artificial selection different from natural selection?
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Artificial selection is selection by human choice rather than environmental change.
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How would evolutionary biologists define the fitness of an organism?
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the ability of an individual to survive and reproduce
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What is the source of variation in a population?
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spontaneous mutations
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If a population of fruit flies is exposed to a food source with high alcohol content, what would happen to the population?
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Individuals who are not tolerant of the ethanol would die, and individuals who are naturally tolerant would survive.
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What is the most important factor in determining the way that a population evolves?
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the environment
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When Darwin was developing his ideas about natural selection, in what area did he have a limited understanding?
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Darwin lacked an understanding about how variation was passed on to offspring
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How do bacterial mutations make bacteria resistant to antibiotics?
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The mutation either disables or counteracts the antibiotic so the bacteria can live in the presence of antibiotics.
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What is the strategy behind combination drug therapy?
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A greater number of changes are required in genetic material for resistance to develop if a greater number of drugs are used.