10 Hallmarks of Cancer Cells – Flashcards

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Sustaining proliferative signaling
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EGFR inhibitors
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Evading growth suppressors
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Cyclin dependent kinase inhibitors
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Avoiding immune destruction
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Immune activating anti-CTLA-4 mab
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Enabling replicative immortality
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Telomerase inhibitors
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Tumor promoting inflammation
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selective anti-inflammatory drugs
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Activating invasion and metastasis
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inhibitors of HGF/c-Met
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Inducing angiogenesis
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VEGF signaling inhibitors
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Genome instability and mutation
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PARP inhibitors
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Resisting cell death
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BH3 mimics
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Deregulating cellular energetics
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Aerobic glycolysis inhibitors
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