Pharmacology – Mid Term

question

Pharmacology is
answer

The study of drugs and their interactions with living organisms
question

The word pharmacology comes from
answer

The Greek word pharmakon and a suffix meaning the study of
question

Drugs have three medical uses. Which of the following is NOT one of those uses?
answer

To cause conditions or diseases
question

The medical use of drugs during radiological procedures and other types of medical tests to provide evidence of a disease process is known as
answer

A diagnostic use
question

The medical use of foxglove to make the drug digoxin (Lanoxin) is an example of a modern drug derived from
answer

Plants
question

The drug Premarin, a female hormone replacement used to treat the symptoms of menopause, is derived from
answer

Pregnant mares’ urine
question

It took a national tragedy to force a much needed update of the Food and Drug Act of 1906. The drug that caused this national tragedy was
answer

Sulfonamide, which was an early anti-infective drug
question

In response to criticism related to the time lag for drug approval, which act was passed in 1997:
answer

Food and Drug Administration (FDA) Modernization Act
question

Prescription drugs are defined as those drugs
answer

That are not safe to use except under professional medical supervision
question

Which of the following statements concerning scheduled drugs is TRUE?
answer

Schedule I drugs have the highest potential for abuse and addiction, while Schedule V drugs have the lowest
question

The Orphan Drug Act was passed to
answer

Facilitate the development of new drugs to treat rare diseases
question

The word pharmacodynamics is concerned with
answer

How drugs produce their effects based on time and dose
question

When analgesic drugs are used to control arthritis pain, this is an example of the ________ use of drugs
answer

Therapeutic
question

Original plant sources of some commonly used drugs today included all of the following EXCEPT
answer

Oak tree
question

Which drugs were introduced in the decade of the 1990s?
answer

Proscar ( for benign prostatic hypertrophy), Nicodern (for stopping smoking), Viagra (for erectile dysfunction)
question

Penicillin was first introduced about the year
answer

1940
question

Aspirin was first introduced about the year
answer

1900
question

The first monoclonal antibody drug Orthoclone OKT3 was developed in
answer

1986
question

Which drug was historically introduced first?
answer

Morphine for pain, from crude opium
question

The government agency responsible for regulating the manufacturing and dispensing of controlled substances is called
answer

Drug Enforcement Agency (DEA)
question

A schedule defines drugs by their
answer

Potential for physical dependence Potential for psychological dependence
question

The Controlled Substances Act created ______ categories of drugs based on their potential for addiction
answer

Five
question

In response to the tragedy of babies born with seal limbs because of thalidomide, this legislation required drugs to be both safe and effective before being marketed
answer

Kefauver-Harris amendment of 1962
question

The belladonna plant was the original source of the drugs ______ that are still used today
answer

Atropine and Scopolamine
question

Powdered rose hips from the rose plant are still used as a natural source of
answer

Vitamin C
question

The Health Insurance Portability and Accountability Act (HIPAA) of 1996 is concerned with the _________ of patient medical and drug information
answer

Security
question

A prescription drug can be obtained with a
answer

Written prescription or verbal order from a helathcare professional whose license permits it Verbal order from a dentist Written prescription from a physician
question

The 1951 Durham-Humphrey Amendment to the Food, Drug and Cosmetic Act defined ________ drugs as those drugs that could only be given to patients under the care of a physician
answer

Prescription
question

Stem cells are cells that are capable of
answer

Differentiating into any type of body tissue
question

Which drug name accurately describes its molecular structure and distinguishes it from all other drugs?
answer

Chemical name
question

Using computers to design new drugs involves _______, which is the study of the chemical structures of drugs and their actions at the molecular level within a cell
answer

Molecular pharmacology
question

In 1982, which drug became the first recombinant DNA technology drug to be approved by the FDA?
answer

Human Insulin (Humulin)
question

From the moment of its discovery or design, every drug has a _________ name that is assigned by the International Union of Pure and Applied Chemistry (IUPAC)
answer

Chemical
question

Which of the following is registered with the US Patent Office as a registered trademark?
answer

Trade name
question

In 2001, the first embryonic stem cell was manipulated to become a
answer

Mature blood cell
question

Once the FDA gives final approval for drug marketing, the drug company creates a
answer

Trade name
question

The drug name that is a registered trademark is the
answer

Brand name
question

The brand name of the drug Lithobid was selected to indicate
answer

How often the drug is to be given
question

In clinical trials, the control group received the
answer

Placebo
question

The patent on a new drug is in effect for ________ years
answer

17
question

There are _________ phases of human testing for new drugs
answer

Three
question

Recombinant DNA technology involves
answer

DNA spliced into a bacterial cell Gene splicing Genetic engineering
question

In vivo testing is
answer

None of the above
question

The United States Adopted Names (USAN) Council
answer

Works with the drug company to determine the generic name for a drug
question

What does therapeutic index indicate?
answer

The margin of safety between the therapeutic and toxic doses
question

The first recombinant DNA technology drug approved by the FDA was
answer

A human version of insulin
question

This drug contains a double-strength dose, as shown by its trade name
answer

Bactrim DS
question

The Human Genome Project
answer

Mapped all 3.2 billion parts of the human genome
question

Placebos commonly are
answer

Injections of sterile normal saline Sugar pills
question

A dextrorotary drug
answer

Example is that of destromethorphan Is an isomer Has a right-facing image for its molecular structure
question

A solid drug form that contains the active drug (as a dried powder) plus inert ingredients to provide bulk is known as a
answer

Tablet
question

What type of tablet has and indented line running across it so that it can be easily broken into equal pieces?
answer

Scored
question

A drug’s trade name will often include abbreviations such as CR, LA, SR, or XL. These abbreviations indicate which type of tablet?
answer

Slow-release
question

Which drug form comes in two different varieties: a soft gelatin shell and two-piece hard shell?
answer

Capsule
question

The category of solutions includes several different drug forms. Which of the following is NOT a type of solution?
answer

Suspension
question

Syrups are
answer

Sweeter and more viscous than elixirs
question

Foams are
answer

Solutions that contain a drug in a water base Expelled from a container when they are used Expanded by tiny aerosol bubbles
question

Suppositories are used to treat patients with
answer

Vomiting
question

Which of the following is NOT a specialized type of tablet?
answer

Elixir
question

The word viscous is used to describe a liquid drug. The word viscous means
answer

Thick or nonwatery
question

Most over-the-counter drugs used to treat coughs are in the drug form of a
answer

Syrup
question

Enteric-coated tablets
answer

Are made to dissolve in the small intestine
question

A solution containing fine, undissolved particles of a drug that settle to the bottom of the container is called a
answer

Suspension
question

Powdered drugs can be found in all of these EXCEPT in
answer

An ampule
question

The word aqueous means _____, while the word viscous means _____
answer

Watery; thick
question

Your friend asks you if you can identify the name of the drug he is taking. He shows you a purple capsule with gold bands. You tell him that this is the drug
answer

Nexium
question

Which of the following drug trade names is NOT in the form of a bead, wafer, or device?
answer

Nexium
question

Which of the following is NOT one of the steps involved in the drug cycle?
answer

Secretion
question

When a drug is applied directly to the skin, eyes, or ears, it is administered via the ______ route
answer

Topical
question

Which is the most convenient route of administration and the one most commonly used?
answer

Oral
question

Which route of administration is chosen when the patient is vomiting and a drug cannot be given by injection?
answer

Rectal
question

Which of the following is NOT a part of the parenteral route of administration?
answer

Endotracheal
question

For most drug forms, absorption involved three steps. Which of the following is NOT one of the three steps of absorption?
answer

Excrete
question

The process of drug metabolism is accomplished in the ____, the principal organ of metabolism
answer

Liver
question

An intravenous drug can be administered in three different ways. Which of the following is NOT one of the three types of intravenous drug administration?
answer

Port
question

Oral drugs that are in a liquid form do NOT go through which of the following steps?
answer

Disintegration
question

Which method of drug administration is only used during emergency resuscitation?
answer

Intracardiac
question

Patients with renal disease and elderly patients with decreased levels of kidney function due to aging are prescribed
answer

Lower doses of drugs
question

The memory aid NAVEL (naloxone, atropine, valium, epinephrine, lidocaine) helps you remember which drugs can be administered
answer

Through an endotracheal tube
question

Any liquid drug that can be given by the oral route can also be given by any of these routes EXCEPT
answer

Transdermal
question

Which of the following routes CANNOT be used to administer drugs to an unconscious patient?
answer

Oral
question

Sublingual administration of a drug involves placing it
answer

Under the tongue
question

Which of the following drugs is given by subcutaneious injection?
answer

Insulin for diabetes mellitus Heparin Allergy shots
question

The first-pass effect describes the
answer

Metabolism of drugs by the liver
question

When a drug is given by inhalation, it is absorbed
answer

Through the alveoli of the lungs
question

Drugs circulate in the blood bound to
answer

Albumin
question

An equivalent word for metabolism is
answer

Biotransformation
question

A drug that is able to unlock or activate a receptor and produce an effect is known as an
answer

Agonist
question

A drug’s main action for which it was prescribed by the physician or other healthcare provider is known as a
answer

Therapeutic effect
question

A toxic effect of a drug results when
answer

The serum level of a drug rises above the therapeutic level
question

Which of the following increases the likelihood of a drug-drug interaction?
answer

Polypharmacy
question

Adrenergic receptors include
answer

Alpha1, Alpha2, Beta1, and Beta2 receptors
question

The presence of an antigen combined with an antibody stimulates the release of ______, which produces mild-to-severe allergic symptoms, depending on the amount released
answer

Histamine
question

Which measurement system is officially known as the International System of Units (SI)?
answer

Metric
question

When a cube is formed that is 1 centimeter long on each side, it becomes a measurement of volume that is abbreviated as
answer

cc
question

Receptors are specifically designed to interact with natural body chemicals. Which of the following is NOT one of those natural body chemicals?
answer

Proteins
question

An antagonist drug
answer

Is similar to inserting the wrong key in a lock Keeps other drugs from activating the receptor Occupies but does not activate the receptor
question

A comon side effect of narcotic drugs used to treat pain is
answer

Constipation
question

The systemic effect of a drug is felt
answer

Throughout the body
question

Symptoms of an allergic reaction are based on the release of
answer

Histamine
question

When a drug has a narrow margin of safety between the correct dose and the toxic dose, the drug is said to have a low
answer

Therapeutic index
question

A drug that can unlock or activate a receptor is known as an
answer

Agonist
question

An idiosyncratic drug reaction is
answer

Based on a patient’s genetic makeup
question

A drug-drug reaction in which the two drugs combine to produce an effect greater than the independent effect of each drug is called
answer

Synergism
question

The therapeutic effect of a drug is usually exterted
answer

On the target organ
question

Which type of drug listed below is NOT measured in units?
answer

Antacid
question

Side effects can be
answer

Mild and temporary Severe enough that the drug must be stopped Moderage and annoying
question

The antibiotic drugs gentamicing and kanamycin are known to exert toxic effects on the ear. This is known as
answer

Ototoxicity
question

When the antibiotic drug tetracycline is taken with an antacid, these two drugs
answer

Form an insoluable complex that prevents a therapeutic effect
question

A _____ prescription is handwritten by the physician on a single preprinted sheet
answer

Written
question

Which type of prescription is typed into the medical office’s computer system, a copy printed out, and then signed by the physician and given to the patient?
answer

Computerized
question

Which type of prescription is generated by a computer and not signed by the physician?
answer

Electronic
question

A pharmacist can fill a prescription without having it on a prescription form and without a physician’s signature for which of the following types of drugs?
answer

Drugs that are not controlled substances
question

Prescriptions for most drugs (except schedule drugs) are valid for how long from the date on the prescription form?
answer

One year
question

Prescriptions for Schedule III through Schedule V drugs are valid for how long from the date on the prescription form?
answer

Six months
question

Prescriptions for Schedule II drugs are valid for how long from the date on the prescription form?
answer

Seven days
question

Which of the following is NOT used when writing a drug name on a prescription?
answer

Chemical name
question

Nonprescription (over-the-counter) drugs
answer

Do not require a prescription and can be purchased by an adult
question

Which type of medication order is carried out (or dispensed) before a physician’s signature is obtained?
answer

Verbal order
question

When blood levels of sodium and potassium are sufficient
answer

Anything in excess of that is excreted in the urine
question

Diuretic drugs
answer

Keep sodium and potassium from being reabsorbed from the tubules back into the blood
question

Which of the following is NOT one of the diseases treated with diuretic drugs?
answer

Urinary tract infections
question

The trade name drugs Naturetin, Diuril, Hygroton, HCTZ, HydroDIURIL, Microzide, Lozol, Enduron, and Zaroxolyn are all examples of which category of diuretic drugs?
answer

Thiazide diuretic drugs
question

The drugs Bumex, Edecrin, Lasix, and Demadex are all examples of which category of diuretic drugs?
answer

Loop diuretic drugs
question

Which of the following drugs in an osmotic diuretic drug?
answer

Mannitol
question

Urinary tract infections (UTIs) are treated with drugs that are particularly effective against
answer

Gram-negative bacteria
question

Which of these anti-infective drugs that inhibit but do not kill the bacteria that cause urinary tract infections?
answer

Sulfonamide drugs
question

Drugs used to treat overactive bladder block the action of ______ to decrease bladder contractions
answer

Acetylcholine
question

If a carbonic anhydrase inhibitor diuretic drug is given, it inhibits the enzyme carbonic anhydrase in the tubule cells. This means that
answer

Bicarbonate and hydrogen ions are not formed
question

Potassium supplements are frequently prescribed for patients taking
answer

Thiazide and loop diuretic drugs
question

The drugs ciprofloxin (Cipro), levofloxacin (Levaquin), and norfloxacin (Noroxin) are drugs used to treat
answer

Prostatis
question

Which of the following class of drugs is NOT given orally?
answer

Prostaglandin E1 drugs
question

Diuretic drugs are commonly used to treat
answer

Hypertension
question

The trade name of the drug furosemide is
answer

Lasix
question

This pellet is inserted into the urethra and produces an erection in patient with erectile dysfunction
answer

Muse
question

Which of the following drugs is used to treat benign prostatic hypertrophy?
answer

Flomax
question

Which of these drug pairs is used to treat urinary tract infections?
answer

Maxaquin and Macrodantin
question

The primary cause of urinary tract infections is
answer

Gram-negative bacteria
question

Which electrolyte must be given in conjunction with some diuretic drugs?
answer

Potassium
question

Patients taking a thiazide or loop diuretic drug but not taking a potassium supplement could develop which of the following adverse effects?
answer

An extremely low level of potassium in the blood Cardiac arrhythmias Hypokalemia
question

Cranberries are effective against urinary tract infections because
answer

They suppress the growth of bacteria because bacteria prefer an alkaline environment The fructose in them prevents bacteria from adhering to the bladder wall They increase the acidity of the urine
question

The drugs Pyridium and the combination drug Pyridium Plus turn the urine an _______ color
answer

Red-orange
question

This drug was approved in 1992 as the first nonsurgical treatment for benign prostatic hypertrophy
answer

Finasteride (Proscar)
question

Which of the following statements is TRUE?
answer

Dutasteride and finasteride are androgen inhibitor drugs Androgen inhibitor drugs, if handled by the pregnant mother, can cause birth defects in a male fetus The packaging and drug inserts for androgen inhibitor drugs warn women not to handle these drugs
question

All of the following are TRUE except
answer

Folic acid antagonist drugs stimulate the formation of folic acid in bacterial cells
question

The combining form vesic/o- as used in the trade name drug Vesicare means
answer

Bladder
question

Urinary tract analgesic drugs
answer

Treat burning, urinary urgency, and painful urination

Get instant access to
all materials

Become a Member