question

which of the following is a primary benefit of the use of computerized physician order entry (CPOE) for patient medications

answer

decreases prescribing and transcription errors

question

incorporating IT into a patient encounter takes skill and tact. durign the encounter, the provider can make the pt more comfortable with the IT the provider is using by

answer

both A and B-turning the screen around so the patient can see material being recorded

question

actions taken to reduce drug-drug interaction problems include all of the following except

answer

prescribing a 3rd drug to counteract the adverse reaction of the combination

question

Sarah developed a rash after using a topical medication. this is a type__ allergic drug reaction

answer

IV

question

cost effectiveness analysis compares 2 or more tx or programs that are

answer

not necessarily therapeutically equivalent

question

herbs and supplements are regulated by the Food and Drug administration

answer

false

question

drug antagonism is best defined as an effect of a drug that

answer

is modified by the concurrent administration of another drug

question

which of the following patients would be at higher risk of experiencing adverse drug reactions

answer

3 month old female

question

the 1st step in the prescribing process according to the world health organizations is

answer

diagnosing the patient's problem

question

pharmacogenetic testing is required by the FDA prior to prescribing

answer

cetuximab

question

drugs that are receptor agonists may demonstrate what property

answer

desensitization or down regulation with continuous use

question

which of the following statements about bioavailability are true

answer

bioavailability issues are especially important for drugs with narrow therapeutic ranges or sustained release mechanisms

question

a potential harmful effect to patients who take some herbal medication is

answer

lead poisoning

question

pharmacokinetic factors that affect prescribing include

answer

bioavailability

question

a provider may consider testing for cyp2d6 variants prior to starting tamoxifen for breast cancer

answer

reduce the likelihood of therapeutic failure with tamoxifen treatment

question

the role of the NP in the use of herbal medication is to

answer

educate patients and guide them to appropriate sources of care

question

the point in time on the drug concentration curve that indicates the first sign of a therapeutic effect is the

answer

onset of action

question

david presents to the clinic with symptoms of allergic conjunctivitis. he is rxd cromolyn sodium (opticrom) eye drops. education regarding cromolyn eye drops includes

answer

he should not wear his soft contacts while using the cromolyn eye drops

question

the pediatric research equity act requires

answer

all applications for new active ingredients, new indications, new dosage forms, or new routes of administration require pediatric studies

question

influenza vaccine may be administered annually to

answer

pregnant patients

question

if a patient is allergic to sulfonamide antibiotics he or she will most likely have cross sensitivity to

answer

all of the above-loop diuretics, sulfonylureas, thiazide diuretics

question

there is often cross sensitivity and cross resistance between penicillins and cephalosporins due to

answer

both drug classes contain a beta lactam ring that is vulnerable to beta lactamase producing organisms

question

Liza is breastfeeding her 2 mth old son and has an infection that requires an abx. what drug factors influence the effect of the drug on the infant

answer

all of above-maternal drug levels, half-life, lipid solubility

question

monitoring for patients who are on long term antifungal therapy with ketoconazole includes

answer

AST, ALT, alkaline phosphatase, and bilirubin

question

drugs that are absolutely contraindicated in lactating women include

answer

antineoplastic drugs such as methotrexate

question

tuberculin purified protein derivative PPD

answer

may be administered the same day as the MMR and or varicella vaccine

question

attenuated vaccines are also known as

answer

live vaccines

question

developmental variation in renal fxn has what impact on rxing for infants and children

answer

lower doses of renally excreted drugs may be prescribed to infants younger than 6 mths

question

Lauren is a 13yr old who comes to clinic with a 4 day history of cough, low grade fever, and rhinorrhea. when she blows her nose or cough the mucous is greenish yellow. the appropriate abx to prescribe would be

answer

none

question

patients who are taking antiretroviral ART need to have the following monitored

answer

lipid levels

question

to prevent the development of peripheral neuropathy in patients taking isonizid for TB, the pt is also prescribed

answer

pyridoxine(Vitamin B 6)

question

the centers for disease control recommends all newborn infants receive prophylactic administration of __ within 1 hr of birth

answer

erythromycin opthalmic ointment

question

Janie presents to clinic with hard ear wax in both ear canals. instructions regarding home removal of hard cerumen includes

answer

instill carbamide peroxide (Debrox) twice daily until canals are clear

question

resistance to antiretroviral ART therapy is measured by

answer

determining plasma viral RNA on two successive measurements

question

predictors for successful treatment with antiretroviral therapy in HIV positive patients includes

answer

the patient is strictly adherent to ART regimen

question

at which stage/classification of htn should drug therapy be instituted according to JNC-7 report

answer

stage 1

question

if not chosen as the first drug in htn tx, which drug class should be added as second step becuase it will enhance the effects of most other agents

answer

diuretics

question

because of its action on various body systems, the patient taking a thiazide or loop diuretic may also need to receive

answer

potassium supplements

question

in teaching about the use of sublingual nitroglycerine, the patient should be instructed

answer

to place on tablet under the tongue if chest pain occurs and allow it to dissolve

question

despite good blood pressure control, a NP might change a patient's drug from an ACEI to an angiotensin II receptor blocker ARB because the ARB

answer

does not produce a dry hacky cough

question

felicity has been prescribed colesipol to tx her hyperlipidemia. unlike other antilipidemics, this drug

answer

exchanges chloride ions for negatively charged acids in the bowel

question

furosemide is added to a tx regimen for heart failure which includes digoxin. monitoring for this combination includes

answer

serum potassium

question

Jacob has htn for which a calcium channel blocker has been prescribed. this drug helps control blood pressure because it

answer

decreases the amount of calcium inside the cell

question

the NP orders a thyroid panel for a pt on amiodarone. the pt tells the NP that he does not have thyroid disease and wants to know why the test is ordered. which is the correct response

answer

amiodarone inhibits an enzyme that is important in making thyroid hormone and cause hypothroidism

question

increased life expectancy for pts with heart failure has been associated with the use of

answer

ace inhibitors, especially when started early in the disease process

question

when considering which cholesterol lowering drug to prescribe which factor determines the type and intensity of treatment

answer

coronary artery disease risk level

question

janice has elevated LDL, VLDL, and trigyceride levels. Niaspan an extended relsease form of niacin is chosen to treat her hyperlidemia. due to its metabolism and excretion, which of the following labs should be monitored

answer

serum creatinine

question

while taking an ARB, pts need to avoid certain OTC meds without first consulting the provider because

answer

both A and B-cimetidine is metabolized by the CYP3A4 isoenzymes and non steroidal anti inflammatory drugs reduce prostaglandin levels

question

when starting a pt on a statin, education would include

answer

all of above-if they stop med, their lipid levels will return to pretreatment, medication is a supplement to diet therapy and exercise, if they have any muscle aches or pain, they should contact their provider

question

angina is produced by an imbalance b/t o2 supply and demand in myocardium. which of the following drugs help to correct this imbalnce by increasing MOS

answer

ACE inhibitor

question

which of the following drugs has been associated with increased risk for MI in women

answer

estrogen replacement

question

TX for heart failure including drug therapy are based on the stages developed by the ACC/AHA. stage A pts are tx with

answer

drugs for hypertension and hyperlipidemia if they exist

question

monitoring of a pt who is on a lipid lowering drug includes

answer

lipid profile with attention to serum LDL, 6-8 wks after starting therapy then again in 6 wks

question

to reduce mortality all pts with angina regardless of class, should be on

answer

aspirin 81-325mg/d

question

which of the following is true about procainamide and its dosing schedule

answer

dose of this drug should be taken evenly spaced around the clock to keep an even blood level

question

serum digoxin level are monitored for potential toxicity, monitoring should occur

answer

because a reference point is needed in adjusting a dose

question

dulcea has type 2 DM and high tricglycerides. she has gemfibrozil prescribed to tx her hypertriglycerideemia. A hx of the following might contraindicate the use of the drug

answer

gall bladder disease

question

pts how have angina, regardless of class, who are also diabetic should be on

answer

ACE inhibitors

question

art is a 55y/o smoker who has been dx with angina and placed on nitrates. he c/o HA after using nitrate. appropriate reply would be

answer

"Headaches are common side effects with these drugs. how severe are they?"

question

Pt teaching r/t amplopidine includes

answer

avoid grapefruit juice as it affects the metabolism of this drug

question

the choice of diuretic use in tx htn is based on

answer

level of kidney fxn with a thiazide diuretic being used for an estimated glomerular filtration rate higher than the mid 40 range

question

some research supports that testosterone replacement therapy may be indicated in which of the following dx in men

answer

all of above- age related decrease in cognitive fxn, metabolic syndrome, decreased muscle mass in aging men

question

while on testosterone replacement, H/H levels should be monitored. levels suggestive of excessive erythorcytosis or abuse are

answer

hemoglobin 17.5g/dl or hematocrit 54%

question

when treating suspected gonorrhea in a non-pregnant pt, the pt should be concurrently tx for chlamydia with

answer

azithromycin 1 gm PO x1

question

the goal of testosterone replacement therapy is

answer

testosterone levels in the mid-normal range in 1 week after an injection

question

when rxing phosphodiesterase type 5 (PDE-5) inhibitors such as sildenafil, viagra, pts should be screened for use of

answer

nitrates

question

ongoing monitoring is essential after tx for gonorrhea. the pt should be rescreened for gonorrhea and chlamydia in

answer

3-6 mths

question

monitoring of an older male pt on testosterone replacement therapy includes

answer

digital rectal prostate screening exam at 3 and 6 mths after starting therapy

question

men who are rxd PDE-5 inhibitors for erectile dysfunction should be educated regarding the adverse effects of the drug which include

answer

hearing loss

question

the choice of diuretic use in tx htn is based on

answer

level of kidney funciton with a thiazide diuretic being used for an estimated glomerular filtration rate higher that the mid 40 range

question

male pts who should not be rxd PDE-5 inhibitors include

answer

those who have had an acute myocardial infarction in the past 6 mths

question

Sophie presents to the clinic with a malodorous vaginal discharge and is confirmed to have trichomonas infections. tx for her would include

answer

metronidazole 2 gm PO x 1 dose

question

monitoring of male pts who are using PDE-5 inhibitors includes

answer

blood pressure

question

Helima presents with a c/o vaginal discharge that when tested meets the criteria for bacterial vaginosis. tx of bacterial vaginosis in a non-pregnant symptomatic women would be

answer

metronidazole 500mg PO BID x 7days

question

A test of cure is recommended after tx chlamydia in which pt population

answer

pregnant patients

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