Patho Chapters 13-19 – Flashcards

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The impulses related to acute pain are usually transmitted by
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myelinated A delta fibers
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According to the gate-control theory, passage of pain may be naturally blocked
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at the synapse by entry of other sensory impulses
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What is the definition of endorphins?
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opiate-like blocking agents in the central nervous system
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A headache that is related to changes in the cerebral blood flow is classified as a/an__________ headache
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migraine
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Which of the following applies to spinal anesthesia?
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the drug is injected into CSF or the epidural space of the spinal cord
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What is the role of nociceptors? They are
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pain receptors that are stimulated by thermal, chemical, or physical means
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Which of the following statement is TRUE?
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young infants respond to pain with tachycardia and increased blood pressure
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Which of the following analgesics acts to reduce pain at the peripheral site?
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acetaminophen
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What is/are the typical effect(s) of psychedelic substances?
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altered perception and awareness as well as hallucinations
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What is physiologic dependence?
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adaptation of the body to a drug resulting in withdrawal signs after the drug is discontinued
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A patient who has developed a tolerance for codeine will
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require a larger dose than expected to control pain
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Which of the following is NOT a common sign(s) of withdrawal?
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respiratory depression
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Withdrawal from any drug is best accomplished
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with medical support
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Which of the following is a synthetic opioid that prevents withdrawal symptoms and improves function?
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methadone
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Which of the following drugs causes headache and vomiting when an alcoholic ingests small amounts of alcohol?
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disulfiram
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What is the official name assigned to a specific drug for worldwide use?
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generic name
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Which is the route of administration by which the larges proportion of the drug dose is likely lost before reaching the site of action?
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oral
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What is the reaction called when two drugs interact to produce a result greater that the sum of individual effects?
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synergism
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In traditional Asian medicine, acupoints are usually located
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on designated meridians
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What are the first priorities in the assessment of a patient in an emergency situation?
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level of consciousness and respiratory function
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A drug that binds with selected specific cell receptors may
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1,2 1.) stimulate activity in those cells 2.) inhibit activity in those cells
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A medical doctor who incorporates drugs, surgery, and manipulations of the musculoskeletal system is classified as a
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osteopath
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A medical history should include all
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1,2,3,4 1.) legally prescribed drugs 2.) vitamin or mineral supplements 3.) any medication not requiring a prescription (over-the-counter items) 4.) herbal treatments
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Antagonistic drugs may be used to
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act as an antidote when necessary
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Which of the following is trained to help individuals with swallowing problems?
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speech-language pathologist
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Which of the following would result from a reduced number of erythrocytes in the blood?
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decreased hematocrit
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What term is used to describe a deficit of all types of blood cells?
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pancytopenia
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Following hemolysis, which part of the hemoglobin molecule produces bilirubin?
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heme
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Vitamin K is required by the liver to synthesize
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prothrombin
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Individuals with type O blood are considered to be universal donors because their blood
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lacks A and B antigens
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Which of the following is considered to be a compensation mechanism for individuals with anemia?
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tachycardia
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Chronic blood loss causes anemia because of the
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smaller amount of recycled iron available
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What is the cause of sickle-cell anemia?
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a defective gene inherited from both parents
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Which of the following best describes the characteristic erythrocyte associated with pernicious anemia?
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megaloblastic or macrocytic nucleated cells
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What causes numbness and tingling in the fingers of individuals with untreated pernicious anemia?
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Vitamin B12 deficit causing peripheral nerve demyelination
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Jaundice is likely to be a sign of __________?
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sickle-cell anemia
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What are the typical early general signs/symptoms of anemia?
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pallor, dyspnea, and fatigue
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What is the cause of oral ulcerations and delayed healing occurring with any sever anemia?
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deficit of oxygen for epithelial cell mitosis
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Which of the following is present with pernicious anemia?
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hypochlorhydria
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Why is pernicious anemia treated with injections of vitamin B12?
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The ingested vitamin would not be absorbed into the blood
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Why do abnormally low hemoglobin values develop with pernicious anemia?
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shorter lifespan of erythrocytes
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What are the common early signs of aplastic anemia?
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excessive bleeding and recurrent infections
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Why do vascular occlusions and infarcts occur frequently with sickle-cell anemia?
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Erythrocytes change shape of when hypoxia occurs
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Which of the following applies to sickle-cell trait?
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sickling of erythrocytes occurs with severe hypoxia
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What is the basic abnormality in thalassemia?
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there is failure to synthesize either the alpha or beta chains in the hemoglobin molecule
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Which of the following is considered to result from a malabsorption problem?
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pernicious anemia
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In individuals with pernicious anemia, antibodies form to
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intrinsic factor or parietal cells
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In cases of polycythemia vera, blood pressure is elevated due to
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increased blood volume/ or increased numbers of circulating blood cells
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Petechiae and purpura are common signs of
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increased bleeding tendencies
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Which statement applies to the disorder hemophilia A?
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hematomas and hemarthroses are common
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Which of the following occur when disseminated intravascular coagulation develops?
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multiple thrombi and deficit of clotting factors
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Which of the following substances is classified as an anticoagulant?
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heparin and prothrombin
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In individuals with acute leukemia, the increased number of malignant leukocytes leads to
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1,2,3,4 1.) decreased hemoglobin 2.) thrombocytopenia 3.) constant bone pain 4.) splenomegaly
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Multiple opportunistic infections develop with acute leukemia primarily because
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many circulating leukocytes are immature
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Why is excessive bleeding a common occurrence with acute leukemia?
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decreased platelets
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Predisposing factors to leukemia commonly include
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exposure to radiation
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Which of the following is typical of Hodgkin's disease?
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initial tumor is single, painless, enlarged lymph node, often cervical
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Non-Hodgkin's lymphoma differs from Hodgkin's lymphoma in that non-Hodgkin's lymphoma usually presents as
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multiple, scattered, enlarged and painless lymph nodes
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Multiple myeloma is a malignant tumor involving
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plasma cells
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What is the primary treatment for the leukemias?
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chemotherapy
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Which of the following statements apply to hemochromocytosis? It is
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a metabolic error leads to excess amounts of hemosiderin, causing damage to organs
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Thalassemia is caused by
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a defect in one or more genes for hemoglobin
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Secondary polycythemia may be associated with
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severe chronic bronchitis
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All of the following apply to vitamin K EXCEPT
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the bone marrow requires to synthesize hemoglobin
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The Reed-Sternberg cell is diagnostic for
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Hodgkin's lymphoma
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Leukemia is sometimes linked to chromosome abnormalities, as evidenced by
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the presence of Philadelphia chromosome translocation in cases of acute myelogenous leukemia (AML)
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Iron-deficiency anemia frequently results from any of the following EXCEPT
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diabetes mellitus
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Which of the following applies to the leukimias?
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Chronic leukemias are more common in older people
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A high percentage of blast cells in the leukocyte population indicates a poor prognosis fro an individual with
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acute myelogenous leukemia
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Which of the following applies to erythropoietin?
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it stimulated production of red blood cells
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Which of the following diagnostic tests would be within the normal range for an individual with hemophilia A?
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bleeding time
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Which of the following applies to the condition disseminated intravascular coagulation (DIC)?
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it is usually a secondary complicaiton
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In which blood dyscrasia does pancytopenia develop?
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aplastic anemia
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Which of the following applies to the etiology of aplastic anemia? It is
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a,c a.) idiopathic in many cases c.) predisposed by exposure to myelotoxins
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Which stage of Hodgkin's lymphoma would be identified when several malignant lymph nodes are found in two regions on the same side of the diaphragm?
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Stage II
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