Module 8 Patho Biology of Cancer – Flashcards

question
The primary function of the nucleus is to?
answer
regulate cell division and control genetic information
question
Which of the following organelles is (are) responsible for processing and packaging proteins into secretory vesicles for transportation to intracellular or extracellular destinations?
answer
golgi apparatus
question
Which of the following cellular structures is (are) involved in cellular communication and cell-to-cell interactions?
answer
Plasma membrane
question
Cell surface markers are composed of?
answer
glycoproteins
question
Plasma membrane receptors are available to bind to?
answer
Ligands
question
In the cell cycle, RNA and protein synthesis takes place during the?
answer
G2 phase
question
Cytokines are?
answer
Growth factors
question
Autocrinesis signifies
answer
a cell signals self
question
Pass from inside the cell inside another
answer
Gap junctions
question
Mutation
answer
All of the above
question
What is correct about mutation
answer
mutations are alteration of DNA sequence
question
Malignant tumors have a tendency to?
answer
All of the above grow rapid, metastasize to distant tissues and invade surrounding tissues
question
Sarcomas are cancers that arise from?
answer
connective tissues
question
Cancer-causing mutations to protooncogenes result in?
answer
increased cell division
question
Mechanisms that cause cancer pain include all of the following except
answer
Cancer cells residing in lymph nodes
question
The process of triggering new blood vessel formation in a tumor is called?
answer
angiogenesis
question
Which of the following is not a typical characteristic of cancer cells?
answer
Decreased responsiveness to growth signals
question
Determining the size of the tumor, the degree of node involvement, and the extent of distant metastasis is called?
answer
Staging
question
Which of the following cancers always arises from an initial mutation in the blood-forming cells of the bone marrow?
answer
Leukemia
question
Cancer-causing mutations of a protooncogene result in
answer
increased cell division
question
Immortality in cancer cells is obtained through the production of?
answer
Telomerase
question
The normal function of tumor suppressor genes in an individual without cancer is to?
answer
control production of anti-growth signals
question
Which of the following mutational routes is necessary to cause cancer with a tumor suppressor gene mutation?
answer
Deletion of both copies of a tumor suppressor gene
question
Normally the tumor suppressor gene p53 induces?
answer
apoptosis
question
One way that a tumor suppressor gene can become inactivated in the absence of mutation or deletion is through gene
answer
silencing
question
Which of the following genetic events is capable of activating oncogenes?
answer
Amplification
question
Viruses are associated with all of the following cancers except?
answer
lung cancer
question
Chronic active hepatitis B infection is a risk factor for developing which of the following types of cancer?
answer
Liver
question
Individual response to pain depends on which of the following factors?
answer
All of the above cultural, Psychologic,Physiologic
question
Pharmacologic therapies for pain management include all of the following except?
answer
beta receptor blockers
question
Which of the following statements about cancer pain is false?
answer
Most patients with cancer experience pain early int the disease processes
question
Apart from diminished physical energy cancer-related fatigue can manifest in which of the following ways?
answer
All of the above
question
Which of the following cell populations do chemotherapeutic agents primarily target?
answer
All rapidly dividing cells
question
Which of the following modes of treatment is not used to eradicate cancer?
answer
Blood transfusions
question
Oral ulcers caused by chemotherapy or radiation therapy is a condition known as?
answer
stomatitis
question
Hair loss from chemotherapy treatment is condition known as?
answer
Alopecia
question
Neuromuscular dysfunction and the release of inflammatory mediators such as tumor necrosis factor and interleukin-1 are thought to be responsible for which of the following manifestations of caners?
answer
Fatigue
question
Which of the following alterations in metabolism is often present in people with cancer?
answer
Increased basic metabolic rate
question
Anemia in individuals with cancer can be the result of all of the following except?
answer
Fatigue
question
Which of the following is an effective treatment for cancer-related or chemotherapy-related anemia
answer
Erythropoietin
question
Leukopenia from cancer or chemotherapy treatment increases an individual's risk for
answer
Infection
question
The wasting syndrome associated with cancer and cancer treatment is called?
answer
cachexia
question
Radon exposure increases an individual's risk for which of the following cancers?
answer
Lung
question
Which of the following viruses has been implicated in the development of cervical cancer?
answer
Human papilloma virus
question
Helicobacter pylori infection is a bacterial cause of
answer
gastric cancer
question
In males increased androgens are associated development of?
answer
Prostate cancer
question
Epigentic factors play a role in?
answer
Gene expression
question
True statements regarding tobacco smoke and cancer
answer
causes cancer in multiple organs as the carcinogen circulate in bloodstream
question
Regular physical activity decreased risk cancer by means of following except
answer
decreased appetite stimulating hormone
question
Mesothelioma is associated
answer
asbestos
question
All the following dietary factors are know to be carcinogenns except
answer
sulphronine in cruciferous vegtables
question
Which of following.....is true regarding exposure of electromagnetic radiation
answer
EMR has been ID possible carcinogen
question
The concept of development plasticity?
answer
body is susceptible to environmental influences in utero and early life
question
Inflammatory cytokines such as those found in UV light exposure......?
answer
Inflammatory cytokines increased risk skin and cancer
question
Tobacco smoking accounts for?
answer
30% deaths
question
Mutations BRCA 1 AND BRAC2
answer
Increased risks breast and ovary cancer
question
Silica exposure
answer
Lung
question
What role estrogen play in.......breast and endometrial cancer
answer
promotes growth in estrogen dependent organs
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question
The primary function of the nucleus is to?
answer
regulate cell division and control genetic information
question
Which of the following organelles is (are) responsible for processing and packaging proteins into secretory vesicles for transportation to intracellular or extracellular destinations?
answer
golgi apparatus
question
Which of the following cellular structures is (are) involved in cellular communication and cell-to-cell interactions?
answer
Plasma membrane
question
Cell surface markers are composed of?
answer
glycoproteins
question
Plasma membrane receptors are available to bind to?
answer
Ligands
question
In the cell cycle, RNA and protein synthesis takes place during the?
answer
G2 phase
question
Cytokines are?
answer
Growth factors
question
Autocrinesis signifies
answer
a cell signals self
question
Pass from inside the cell inside another
answer
Gap junctions
question
Mutation
answer
All of the above
question
What is correct about mutation
answer
mutations are alteration of DNA sequence
question
Malignant tumors have a tendency to?
answer
All of the above grow rapid, metastasize to distant tissues and invade surrounding tissues
question
Sarcomas are cancers that arise from?
answer
connective tissues
question
Cancer-causing mutations to protooncogenes result in?
answer
increased cell division
question
Mechanisms that cause cancer pain include all of the following except
answer
Cancer cells residing in lymph nodes
question
The process of triggering new blood vessel formation in a tumor is called?
answer
angiogenesis
question
Which of the following is not a typical characteristic of cancer cells?
answer
Decreased responsiveness to growth signals
question
Determining the size of the tumor, the degree of node involvement, and the extent of distant metastasis is called?
answer
Staging
question
Which of the following cancers always arises from an initial mutation in the blood-forming cells of the bone marrow?
answer
Leukemia
question
Cancer-causing mutations of a protooncogene result in
answer
increased cell division
question
Immortality in cancer cells is obtained through the production of?
answer
Telomerase
question
The normal function of tumor suppressor genes in an individual without cancer is to?
answer
control production of anti-growth signals
question
Which of the following mutational routes is necessary to cause cancer with a tumor suppressor gene mutation?
answer
Deletion of both copies of a tumor suppressor gene
question
Normally the tumor suppressor gene p53 induces?
answer
apoptosis
question
One way that a tumor suppressor gene can become inactivated in the absence of mutation or deletion is through gene
answer
silencing
question
Which of the following genetic events is capable of activating oncogenes?
answer
Amplification
question
Viruses are associated with all of the following cancers except?
answer
lung cancer
question
Chronic active hepatitis B infection is a risk factor for developing which of the following types of cancer?
answer
Liver
question
Individual response to pain depends on which of the following factors?
answer
All of the above cultural, Psychologic,Physiologic
question
Pharmacologic therapies for pain management include all of the following except?
answer
beta receptor blockers
question
Which of the following statements about cancer pain is false?
answer
Most patients with cancer experience pain early int the disease processes
question
Apart from diminished physical energy cancer-related fatigue can manifest in which of the following ways?
answer
All of the above
question
Which of the following cell populations do chemotherapeutic agents primarily target?
answer
All rapidly dividing cells
question
Which of the following modes of treatment is not used to eradicate cancer?
answer
Blood transfusions
question
Oral ulcers caused by chemotherapy or radiation therapy is a condition known as?
answer
stomatitis
question
Hair loss from chemotherapy treatment is condition known as?
answer
Alopecia
question
Neuromuscular dysfunction and the release of inflammatory mediators such as tumor necrosis factor and interleukin-1 are thought to be responsible for which of the following manifestations of caners?
answer
Fatigue
question
Which of the following alterations in metabolism is often present in people with cancer?
answer
Increased basic metabolic rate
question
Anemia in individuals with cancer can be the result of all of the following except?
answer
Fatigue
question
Which of the following is an effective treatment for cancer-related or chemotherapy-related anemia
answer
Erythropoietin
question
Leukopenia from cancer or chemotherapy treatment increases an individual's risk for
answer
Infection
question
The wasting syndrome associated with cancer and cancer treatment is called?
answer
cachexia
question
Radon exposure increases an individual's risk for which of the following cancers?
answer
Lung
question
Which of the following viruses has been implicated in the development of cervical cancer?
answer
Human papilloma virus
question
Helicobacter pylori infection is a bacterial cause of
answer
gastric cancer
question
In males increased androgens are associated development of?
answer
Prostate cancer
question
Epigentic factors play a role in?
answer
Gene expression
question
True statements regarding tobacco smoke and cancer
answer
causes cancer in multiple organs as the carcinogen circulate in bloodstream
question
Regular physical activity decreased risk cancer by means of following except
answer
decreased appetite stimulating hormone
question
Mesothelioma is associated
answer
asbestos
question
All the following dietary factors are know to be carcinogenns except
answer
sulphronine in cruciferous vegtables
question
Which of following.....is true regarding exposure of electromagnetic radiation
answer
EMR has been ID possible carcinogen
question
The concept of development plasticity?
answer
body is susceptible to environmental influences in utero and early life
question
Inflammatory cytokines such as those found in UV light exposure......?
answer
Inflammatory cytokines increased risk skin and cancer
question
Tobacco smoking accounts for?
answer
30% deaths
question
Mutations BRCA 1 AND BRAC2
answer
Increased risks breast and ovary cancer
question
Silica exposure
answer
Lung
question
What role estrogen play in.......breast and endometrial cancer
answer
promotes growth in estrogen dependent organs