Mannitol (Osmitrol, Resectisol) – Flashcards

Osmotic Diuretic

diuretics Pregnancy Category C drug.

Used in acute renal failure, high intraocular or intracranial pressure, edema, and drug intoxication (to induce diuresis). Mannitol works along the entire nephron and is non-absorbable. It inhibits reabsorption of H2O and lytes. Take away- mannitol is pulling fluids from the interstitial spaces into the vasculature.

hypokalemia increases risk for dig toxicity

known allergy, severe pulmonary edema (use loop diuretics instead), anuria, severe dehydration, pulmonary congestion, active intracranial bleeding. Use caution in clients who have HF.

Mannitol may crystallize at low temperatures so it needs to be stored in a warmer. Because of this, it is always administered IV through a filter. Visually inspect mannitol container for precipitants prior to administration.

Immediately terminate treatment if severe cardiac or renal impairment develop after initiation of therapy.

Convulsions, thrombophlebitis, pulmonary congestion or edema, HF,, kidney failure, fluid and lyte imbalances, increased GFR and renal plasma flow, h/a, chest pain, tachycardia, blurred vision, chills, fever

Administer by continuous IV infusion. Use a filter needle when drawing from the vial and a filter in the IV tubing to prevent administration of microscopic crystals. Monitor daily weight, I&O, serum lytes & for signs of dehydration, acute kidney injury, and edema.