Lfcc Bio 150 Test Questions – Flashcards
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Yersinia pestis Disease |
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Bubonic plague |
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Yersinia pestis Causative agent |
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Gram - rod bacteria |
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Yersinia pestis Mode of transmission |
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Fleas on vertebrates |
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Reasons to study Microbiology |
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1. Important to human health 2. Primary producers [decompose dead organisms/waste] 3. Genetic engineering 4. Food/food industry |
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3 reasons Microorganisms are useful in research |
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1. Simple structure [single cell] 2. Large #'s [statistically reliable] 3. Reproduce quickly [20-40 min can be a generation]. |
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Basic Funcitons of Organisms [6] |
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1. Organization 2. Responsiveness 3. Growth & Differentiation 4. Reproduction 5. Movement 6. Metabolism & Excretion |
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Bioremediation |
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microorganisms are genetically engineered to break down toxic materials |
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Polymers/molecules |
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Carbs, lipids, proteins, nucleic acids |
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Why are bacteria everywhere on this planet? |
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- metabolic capacity superior to any other form of life - can titilize and inorganic or organic material as a source of energy. |
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pleamorphic |
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can change form or shape |
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Cell |
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lowest functional unit of life ex. bacteria, plant & animal cell, human egg |
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Major groups of organisms include |
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- bacteria - viruses - algae - protozoa - fungi |
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Levels of Organization |
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Atom molecule organelles cell tissue organs organ systems organism |
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bacterial characteristics/properties |
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- all prokaryotic [single cell, no nucleus, but does have genome] - some autotrophic [photosynthesis] - most heterotrophic [eat product of autotroph or eat autotroph] - most do not cause disease - most have not been identified or grown |
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bacteria |
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living, single cellular infectious agent |
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Virus properties/characteristics |
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- acellular infectious agent - consists of a genome [either DNA or RNA single or double stranded] and protein coat - obligate intracellular parasites [only way to replicate is within another cell] |
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Viroid |
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1. smaller than virul 2. RNA [Ribonucleic Acid] single strand 3. Infects plants [infectious agent] |
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Viron |
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complete virus. Consists of lipid envelope, genome, and protein coat. |
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Algae |
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- most do not cause disease - all are eukaryotic - most single cellular - all are autotrophic |
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Protozoa |
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- most single cell - eukaryotic - atleast 1 nucleus - some cause disease |
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Eukaryotic |
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- genome in nucleus - most heterotrophic - can be single or multicellular - some autotrophic [such as algae] |
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Protozoa |
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- single celled w/ atleast 1 nucleus - some cause disease - some eat bacteria through phagocytosis |
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Prion |
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- single misshaped protein [causes other proteins to become misshapedn - causes neurodegenerative diseases such as mad cow disease |
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Multicellular Animal Parasites |
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- Eukaryotic - Multi-cellular animal - such as parasitic worms |
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Helminths |
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parasitic flatworms and round worms |
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Arthropods role with microbes |
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- [such as insects] serve in transmission of microbes |
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Hooke |
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- [Mid 1600s] compound microscope - named "cells" |
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Leeuwenhoek |
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-[mid 1600s] developed 1st usable microscope - observed living microorganisms. |
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spontaneous generation |
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belief that microorganisms arose from nonliving things |
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Biogenesis |
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- beleif that living organisms arise from preexisting life. - lead to the cell theory - was an alternate hypothesis |
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Germ Theory of Disease |
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States that microorganisms (germs)can invade other organisms and cause disease |
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Pasteur |
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-[mid 1800s] Father of Immunology -1st rabies vaccine |
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Koch |
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- [late 1800s]developed a technique for growing pure cultures [which lead to ability to treat diseases]. - came up with concept "1 organism = 1 disease" - worked with anthrax and tuberculosis |
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Koch's Postulates |
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1. The same causative agent must be found in all cases of the disease 2. The disease organism must be isolated in a pure culture. 3. This pure culture must cause disease in a healthy, susceptible animal. 4. The disease organism must be recovered from teh inoculated animal. |
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Acellular infectious agents |
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Viroid, Viron, Virus, Prion |
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Koch's Postulates |
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1. The same causative agent must be found in all cases of the disease 2. The disease organism must be isolated in a pure culture. 3. This pure culture must cause disease in a healthy, susceptible animal. 4. The disease organism must be recovered from teh inoculated animal. |
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Joseph Lister |
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- [mid 1800s] developed aseptic techniques in surgery - Hint Lister [Listerine] |
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Edward Jenner |
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- [late 1700s] discovered cowpox prevented smallpox - called Vaccine "vacca" - would cut patient and place scabs from milk maids into would to prevent smallpox |
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vacca |
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- latin for "cow" - term Edward Jenner used for vaccine |
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Chemotherapy |
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uses chemicals to treat an infectious agent [such as bacteria] |
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Virulent bacteria |
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- kills target animal - contains thick polysacharide coating |
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Modern Developments in Microbiology |
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- Virology - study of viruses - Bacteriology - study of bacteria - Mycology - study of fungi - Parasitology - study of protozoa and parasitic worms - Genetis and Microbiology |
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Griffith |
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[1928] discovered that live bacteria could acquire heritable traits from dead ones. |
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Prokaryot |
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single cell, no nucleus |
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Prokaryote |
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single cell, no nucleus [but does contain a genome] |
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Viroid |
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1. smaller than a virus 2. Single stranded RNA [ribonucleic acid] 3. Infects plants [infectious agent] |
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Viron |
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Complete virus. Composed of lipid envelope, genome, & a protein coat |
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Prion |
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1. single misshaped protein 2. Causes neurodegenerative diseases such as Mad Cow |
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Virus |
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1. acellular 2. obligate intracellular parasites [only way to reproduce is within another cell. |
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Algae |
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1. most do not cause disease 2. all are eukaryotic 3. all autotrophic 4. most single cellular |
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Eukaryotic |
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1. genome in nucleus 2. most heterotrophic 3. can be single or multicellular 4. some autotrophic [such as algae] |
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Bacteria |
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1. all prokaryotic [single cell, no nucleus] 2. some autotrophic [photosynthesis] 3. most heterotrophic [ingest product of autotrophes 4. most do not cause disease 5. most have not been identified or grown |
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Types of infectious agents |
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Viruses, viroid, prion, and some bacteria |
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antibiotics |
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chemicals produced by bacteria and fungi that inhibit or kill other microbes |
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Quinine |
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from tree bark was long used to treat malaria |
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Alexander Fleming |
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discovered first antibiotic [Penicillin killed S. aureus] |
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Parasitology |
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study of larger and more complex organisms |
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Griffith [1928] |
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discovered live bacteria could acquire heritable traits from dead ones - Streptococcus pnemonia: Avirulent = living, virulent = dead, heat killed virulent + avirulent = dead - transformation through genetic recombination |
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Transformation |
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form of genetic recombination |