Lfcc Bio 150 Test Questions – Flashcards

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Yersinia pestis Disease
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Bubonic plague
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Yersinia pestis Causative agent
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Gram - rod bacteria
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Yersinia pestis Mode of transmission
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Fleas on vertebrates
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Reasons to study Microbiology
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1. Important to human health
2. Primary producers [decompose dead organisms/waste]
3. Genetic engineering
4. Food/food industry
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3 reasons Microorganisms are useful in research
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1. Simple structure [single cell]
2. Large #'s [statistically reliable]
3. Reproduce quickly [20-40 min can be a generation].
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Basic Funcitons of Organisms [6]
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1. Organization
2. Responsiveness
3. Growth & Differentiation
4. Reproduction
5. Movement
6. Metabolism & Excretion
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Bioremediation
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microorganisms are genetically engineered to break down toxic materials
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Polymers/molecules
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Carbs, lipids, proteins, nucleic acids
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Why are bacteria everywhere on this planet?
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- metabolic capacity superior to any other form of life
- can titilize and inorganic or organic material as a source of energy.
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pleamorphic
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can change form or shape
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Cell
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lowest functional unit of life
ex. bacteria, plant & animal cell, human egg
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Major groups of organisms include
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- bacteria
- viruses
- algae
- protozoa
- fungi
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Levels of Organization
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Atom
molecule
organelles
cell
tissue
organs
organ systems
organism
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bacterial characteristics/properties
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- all prokaryotic [single cell, no nucleus, but does have genome]
- some autotrophic [photosynthesis]
- most heterotrophic [eat product of autotroph or eat autotroph]
- most do not cause disease
- most have not been identified or grown
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bacteria
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living, single cellular infectious agent
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Virus properties/characteristics
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- acellular infectious agent
- consists of a genome [either DNA or RNA single or double stranded] and protein coat
- obligate intracellular parasites [only way to replicate is within another cell]
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Viroid
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1. smaller than virul
2. RNA [Ribonucleic Acid] single strand
3. Infects plants [infectious agent]
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Viron
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complete virus. Consists of lipid envelope, genome, and protein coat.
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Algae
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- most do not cause disease
- all are eukaryotic
- most single cellular
- all are autotrophic
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Protozoa
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- most single cell
- eukaryotic
- atleast 1 nucleus
- some cause disease
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Eukaryotic
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- genome in nucleus
- most heterotrophic
- can be single or multicellular
- some autotrophic [such as algae]
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Protozoa
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- single celled w/ atleast 1 nucleus
- some cause disease
- some eat bacteria through phagocytosis
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Prion
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- single misshaped protein [causes other proteins to become misshapedn
- causes neurodegenerative diseases such as mad cow disease
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Multicellular Animal Parasites
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- Eukaryotic
- Multi-cellular animal
- such as parasitic worms
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Helminths
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parasitic flatworms and round worms
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Arthropods role with microbes
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- [such as insects] serve in transmission of microbes
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Hooke
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- [Mid 1600s] compound microscope
- named "cells"
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Leeuwenhoek
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-[mid 1600s] developed 1st usable microscope
- observed living microorganisms.
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spontaneous generation
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belief that microorganisms arose from nonliving things
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Biogenesis
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- beleif that living organisms arise from preexisting life.
- lead to the cell theory
- was an alternate hypothesis
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Germ Theory of Disease
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States that microorganisms (germs)can invade other organisms and cause disease
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Pasteur
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-[mid 1800s] Father of Immunology
-1st rabies vaccine
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Koch
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- [late 1800s]developed a technique for growing pure cultures [which lead to ability to treat diseases].
- came up with concept "1 organism = 1 disease"
- worked with anthrax and tuberculosis
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Koch's Postulates
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1. The same causative agent must be found in all cases of the disease
2. The disease organism must be isolated in a pure culture.
3. This pure culture must cause disease in a healthy, susceptible animal.
4. The disease organism must be recovered from teh inoculated animal.
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Acellular infectious agents
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Viroid, Viron, Virus, Prion
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Koch's Postulates
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1. The same causative agent must be found in all cases of the disease
2. The disease organism must be isolated in a pure culture.
3. This pure culture must cause disease in a healthy, susceptible animal.
4. The disease organism must be recovered from teh inoculated animal.
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Joseph Lister
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- [mid 1800s] developed aseptic techniques in surgery

- Hint Lister [Listerine]
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Edward Jenner
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- [late 1700s] discovered cowpox prevented smallpox
- called Vaccine "vacca"
- would cut patient and place scabs from milk maids into would to prevent smallpox
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vacca
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- latin for "cow"
- term Edward Jenner used for vaccine
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Chemotherapy
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uses chemicals to treat an infectious agent [such as bacteria]
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Virulent bacteria
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- kills target animal
- contains thick polysacharide coating
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Modern Developments in Microbiology
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- Virology - study of viruses
- Bacteriology - study of bacteria
- Mycology - study of fungi
- Parasitology - study of protozoa and parasitic worms
- Genetis and Microbiology
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Griffith
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[1928] discovered that live bacteria could acquire heritable traits from dead ones.
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Prokaryot
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single cell, no nucleus
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Prokaryote
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single cell, no nucleus [but does contain a genome]
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Viroid
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1. smaller than a virus
2. Single stranded RNA [ribonucleic acid]
3. Infects plants [infectious agent]
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Viron
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Complete virus. Composed of lipid envelope, genome, & a protein coat
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Prion
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1. single misshaped protein
2. Causes neurodegenerative diseases such as Mad Cow
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Virus
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1. acellular
2. obligate intracellular parasites [only way to reproduce is within another cell.
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Algae
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1. most do not cause disease
2. all are eukaryotic
3. all autotrophic
4. most single cellular
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Eukaryotic
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1. genome in nucleus
2. most heterotrophic
3. can be single or multicellular
4. some autotrophic [such as algae]
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Bacteria
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1. all prokaryotic [single cell, no nucleus]
2. some autotrophic [photosynthesis]
3. most heterotrophic [ingest product of autotrophes
4. most do not cause disease
5. most have not been identified or grown
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Types of infectious agents
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Viruses, viroid, prion, and some bacteria
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antibiotics
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chemicals produced by bacteria and fungi that inhibit or kill other microbes
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Quinine
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from tree bark was long used to treat malaria
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Alexander Fleming
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discovered first antibiotic [Penicillin killed S. aureus]
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Parasitology
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study of larger and more complex organisms
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Griffith [1928]
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discovered live bacteria could acquire heritable traits from dead ones
- Streptococcus pnemonia: Avirulent = living, virulent = dead, heat killed virulent + avirulent = dead
- transformation through genetic recombination
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Transformation
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form of genetic recombination
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