Test Answers on Exam 1 – Microbiology – Flashcards
Unlock all answers in this set
Unlock answersquestion
What does the host provide to the parasite? |
answer
1. Space to live 2. Food 3. Protection |
question
Homogenetic |
answer
Relationship between 2 individuals ain the same species |
question
Heterogenetic |
answer
Relationship between 2 individuals of different species |
question
Competition |
answer
2 species compete for same resources |
question
Predation |
answer
One species kills and eats another |
question
Symbiotic |
answer
2 organisms living in close association |
question
Symbiosis includes |
answer
Phoresis Commensalism Parasitism Mutalism |
question
Phoresis |
answer
2 symbiants traveling together |
question
Commensalism |
answer
1 symbiant benefits and the other is unaffected |
question
Parasitism |
answer
1 symbiant benefits and the other is negatively affected |
question
Mutalism |
answer
Both symbiants benefit |
question
Animal parasites are found in 3 goups |
answer
Protozoa (Unicellular) Helminths (Worms) Arthropoda |
question
Helminths (worms) include |
answer
Nematoda (Roundworms) Trematoda (Flukes) Cestoda (Tapeworms) |
question
Platyhelminths (Dorso-ventrally flat) |
answer
Trematoda and Cestoda |
question
Invasion |
answer
1 organism gains access to the surface or internal tissues of another (little or no increase in numbers) |
question
Infestation |
answer
1 organism gains access to the surface or tissues of another and small increase in numbers (Small = 10-dozens) |
question
Infection |
answer
1 organism gains access to the surface or tissues of another and a huge (100's-millions) increase in numbers |
question
While a predator may participate in destructive consumption a parasite feeds by |
answer
Cropping (Eating little by little) |
question
While the nutrition provided by the victim is the whole body or selected tissues for predators, it is ____ for parasites |
answer
Fragments, fluids, etc |
question
While a predator may be lethal to its victim |
answer
A parasite is rarely lethal |
question
While a predator may coexist with its prey, a parasite may live |
answer
In or on its host |
question
While a predator may be large or strong, a parasite is usually |
answer
Smaller or much smaller |
question
Fewer predators than |
answer
Parasites |
question
While a predator may come in contact with its prey momentarily, a parasite |
answer
Comes in contact with its prey for a prolonged and/ or repeated amount of time |
question
While a predator may "herd" for protection, a parasite |
answer
Will not herd |
question
While a predator usually won't cause disease unless its related to stress, a parasite |
answer
Will often cause direct disease |
question
Life cycle of Entamoeba histolytica |
answer
1. Person ingests cyst in contaminated food or water 2. Travels to Ileum and excysts 3. Divides via binary fission and matures to Trop stage 4. Matures in mucosal crypts |
question
Amoebic dysentery |
answer
Entamoeba histolytica dissolves mucosa to get at RBC's in capillaries for oxygen which causes the host irritation |
question
Pathophysioogy of an entamoeba histolytica infection |
answer
Mucosal infiltrate Ulceration in the cecum Gall Bladder-like symptoms Small flask ulcerations Rare- Affects the heart and lungs Very rare- Amoebic lung excess and histolysis of brain tissue |
question
Three stages of Entamoeba histolytica infection |
answer
1. Noninvasive colonization 2. Intestinal disease (Diarrhea, dysentary) 3. Extra intestinal colonization (Break out to any other place in the body) |
question
Excystation of Enatamoeba histolytica occurs |
answer
Outside the body |
question
Trophozoite form of Enatamoeba histolytica occurs |
answer
Inside the body |
question
Metacyst of Enatamoeba histolytica occurs |
answer
Inside the ilium before the troph stage |
question
Granulomatous amebic encephalitis (GAE)signs and symptoms include |
answer
Headaches Stiff neck Nausea Vomitting tiredness |
question
GAE causative organism |
answer
Acathamoeba spp |
question
GAE begins when |
answer
Organism enters via lungs and spreads to CNS. Slow and chronic onset that is mostly found in ICP's |
question
What may be found in patients with GAE? |
answer
Trophs found in CSF or brain plus cysts in the brain |
question
Amebic keratitis (AK) |
answer
Disorder of the eyes produced by off-label (prolonged) use of disposable contact lenses |
question
Risk factors of AK include |
answer
Corneal foreign body Contact with non-sterile water Neurotrophic keratopathy Herples simplex karatits Radial kertomy Off-label contact lens use |
question
Patients with AK present with |
answer
question
Giardia lamblia |
answer
First discovered in 1681 by Leeuwenjoek in his stool. Called it pissabed 1859 Vilem Lambl calle it cercomonas intestinalis 1879 Kuntsler found giardia like organism and called it Giardia agilis 1915 Stiles found Giardia lamblia |
question
Giardia lamblia patho |
answer
Infects the upper respiratory tract and may penetrate to liver and gall bladder. May cause irritation to mucosal lining. May need 5 or 6 stool specimen |
question
Giardia lamblia life cycle (Takes 6-8 hours) |
answer
1. Person eats cyst 2. Excyst in the duodenu and divides via binary fission 3. Recyst before it reaches the rectum |
question
Giardia lamblia cyst |
answer
Has up to 4 nuclei. |
question
Giardia lamblia symptoms |
answer
Mild diarrhea, anorexia, flatulence, decrease serum protein, gamma globulin, folic acid and fat soluble vitamins |
question
Chilomastix mesnili |
answer
Non pathogen. Cyst looks like lemon drop. |
question
Trichamonas hominis |
answer
Only intestinal flagellate with no cyst. Non pathogen |
question
Trichamonas vaginalis |
answer
Found in the Gentro-urinary tract (Similar to trich. hominis) causes vaginal discharge, burning, itching in female. Often aymptomatic in males |
question
Best specimen for trich vaginalis |
answer
Urethral, vaginal, prostate, urine. Should be collected warm in 2-3% glucose with 0.87% Nacl |
question
Trichamonas tenax. (Trich buccalis) |
answer
Found in the tarter of teeth in the pyorrheal pockets and tonsilar crypts |
question
Trichamonas tenax spread via |
answer
Shared contaminated dished, drinking glasses, respiratory pathogen |
question
Enterobius hominis |
answer
Rare, tropical and temperate areas, not a pathogen |
question
Retortamonas intestinalis (also called Embadomonas spp) |
answer
Not common, only seen in tropical and temperate regions. Troph small with 2 anterior flagella and cytosome near nucleus |
question
Retortamonas intestinalis cyst |
answer
Smaller then troph has 1 large nucleolus. Contains "Bird's Beak fibrils" (piece left over from troph form) |
question
Dientamoeba fragilis |
answer
Cosmopolitan organism. Very resistant, possible pathogen. Considered ameboflagellate. Can live in mucosal crypts, ingest rbc's. Found in most mental health facilities and pediatric populations |
question
Dientamoeba fragilis symptoms |
answer
Diarrhea, abdominal pain, nausea, anorexia, vomiting, fatigue |
question
Intestinal cilliates |
answer
Balantidium coli |
question
Balantidium coli |
answer
Found in tropical and temperatre regions, common in hogs and monkeys. Found in the lg intestine and cecum, eat bacteria, ingress organism |
question
Balandtidium coli troph |
answer
Covered with cilia |
question
Balantidium coli life cycle |
answer
1. person eats it 2. excysts 3. Divides 4. Feeds on mucosal crypts 5.Encysts 5. Shit out |
question
Balantidium coli patho |
answer
Patients are asymptomatic or may have severe dysentary for weeks to months. Can penetrate tissue. Produces hyaluronidase |
question
Malaria related organisms (Falciparum organisms) are in the order and class |
answer
Eucoccidiida |
question
80% of all Malaria cases are caused by the organism. |
answer
Plasmodium vivax. |
question
15% of all Malaria cases are caused by the organism |
answer
Plasmodium falciparum |
question
Where did malaria parasites originate? |
answer
Africa and fossils of mosquitos |
question
What are the vectors for Malaria? |
answer
Anopheles spp. mosquitos |
question
What is the most pathogenic species of plasmodium? |
answer
Falciparum |
question
Plasmodium life cycle (Exoerythytic shigonomy portion) |
answer
1. Take bloodmeal from person and inject infective stage sporozoites into another human via the capillaries in the human peripheral CVS 2. Escape to liver within 40 mins 3. Invade pharyngeal cell |
question
Plasmodium life cycle after exoerythytic shigonomy |
answer
1. Development continues to mature EES schizont 2. Once mature schizont ruptures, releasing merozoites into the blood that enter gametocytosis in the peripheral blood |
question
Merozoites have apex (front ends) and are said to be |
answer
Apicomplexical organisms |
question
Plasmodium escapes via |
answer
Proteases (Falciparum and chlamydia) Pore-forming proteins (PFP's) Unique methods (Toxoplasma gondii) |
question
Erythrocyte schizogony proceeds from |
answer
Young troph-Applique forms, motile, contribute to early stippling Immature schizont- 2 or more nuclei, more stippling and expanded cytoplasm Mature schizont- Max stippling and a lot of endomitotic reduction division Merozoites released |
question
Merozoites that enter RBC to begin the process of gametogenesis create |
answer
Microgametocytes (Male) Macrogametocytes (Female) Which can be picked up by the mosquito in another blood meal |
question
What happens when ingested gametocytes begin sporogeny in a new mosquito? |
answer
Sporogeny begins in mosquito GIT, microgametocyte emerges from its ingest RBC s a motile sperm and fertilizes macrogametocyte. Zygote (Product of sperm and egg) form a sporozoite |
question
Ookinete |
answer
Develops from fertilized plasmodium ova. Matures via EMRD to sporozoites. Invades mosquito GIT epithelial cells |
question
Where must the sporozoite mature in the mosquito to enter the infective stage? |
answer
In the salivary glands |
question
Merozoite |
answer
Non-motile and invades RBC's |
question
Sporozoite |
answer
Motile Invades liver cells |
question
What can result due to cellular material buildup caused by malaria? |
answer
Nephrotic syndrome |
question
Plasmodium vivax |
answer
Found in almost all endemic areas. Infected RBC's appear to be larger than non-infected RBC's. May have Schuffner's Dot 10-17 day inc period |
question
Young plas vivax troph |
answer
Applique form |
question
PLas vivax symptoms include |
answer
Headache, photophobia, Musular aches, nausea, vomitting. |
question
Plasm vivax Primary attack stage |
answer
Primary attack followed by periodic paroxysms and sudden chills, hot stage, severe frontal headaches, backaches. Patient becomes excited flushed and disoriented |
question
Plasm vivax sweating stage |
answer
Profuse sweating, exhausted (sleeps 10-12 hours), feels fine upon awakening |
question
The effects of plasm vivax due to hemolysis and liberation of RBC metabolites. In vivax malaria only what cell is affected and what does this cause? |
answer
Retics Causes increased phagocytosis, hemolysis, spleen size and liver size Malarial pigment may collect in the spleen |
question
For what type of malaria would it not be unusual to get thrombosis in the capillaries of the brain and why? |
answer
Falciparum Because of the antigen antibody complex |
question
Malaria serum chemistry results |
answer
Decreased albumin and globulin Increased potassium due to hemolysis |
question
Plas falciparum fever pattern |
answer
Merezoites released= High fever Schizogony = Temp fluctuates and then decreases Merozoites released again = High temp |
question
Anemia due to malaria would cause |
answer
Microcytosis, hypochromia due to hemolysis by parasite, interference with hematopoiesis and capillary hemorrhage |
question
Blackwater Fever |
answer
Occurs during falciparum infection Intravascular hemolysis, hemoglobinemia and hemoglobinuremia. Hemoglobin cysts and tubular epithelial cells in the urine (Pee is black) |
question
Hemoflagelates are |
answer
Likely pathogens in certain situations |
question
Anoher name for Leishmanial stage |
answer
Amastigote |
question
Anoher name for Leptomonad stage |
answer
Promastigote |
question
Another name for Crithidial stage |
answer
Epimastigote |
question
Anoher name for Trypanosomal stage |
answer
Trypanomastigote |
question
Hemoflagelates replicate by |
answer
3-step process that involves longitudinal fission |
question
Trypanosoma brucei |
answer
Causes African trypanosomiasis |
question
Trypanosoma brucei Life cycle for |
answer
1.Take blood meal which contains trypanosomal stage. 2. Morphs into crithidial stage 3. Another fly takes blood meal with the organisms in the crithidial stage 4. Those organisms then molt into the trypanosomal stage |
question
Why does molting in the Tse tse fly occur? |
answer
Due to metabolic differences in teh GIT of the Tsetse fly vs the human CVS |
question
Vector for trypanosoma brucei |
answer
Glossina palpalis (W) Glossina mordisans (E) "Tsetse Fly" |
question
Trypanosoma brucei inc period |
answer
5-30 days Trypanosomal stages in the patient's CVS Blood smear pos Parasitemia fluctuates Trypanosomes invade the lymphatics and colonize the lymph nodes Enlargement of the cervical LNS (Winterbottom's sign) Increased lymph count Increased IgM |
question
Syndrome phase of Trypanosoma brucei |
answer
Trypanosomes invades the CNS Apathy Fatigability Somnolence sleepy Emaciation Character changes Paraplegia Coma Death |
question
What kind of specimen is appropriate late in the process for both Trypanoma species |
answer
CSF |
question
Example of how human error can increase parasites |
answer
Europeans teach Africans to burn grass at then end of growing season to return nitrogen to the soil quicker. Burning of the grass reduced ant population which is the predator of the Glossima pupae. Without ants the Glossima pupae increased. Europeans shot leopards who were the primary predators of antelope whose population increased. The increase in Antelope caused an increase in Glossima who were their primary food source. |
question
Nematode |
answer
"Roundworms" Contain a plasmid (Olfactory organ), most are freelviing, important parasites of plants and about 80,000 are parasites to vertebrates.Found in warm region of the world. Females usually twice the size of males. |
question
General characteristics of Nematodes |
answer
Oral opening Anterior digestive tract Muscular esophagus Usually pale in color unless gravid female Non-cellular (secreted) hard cuticle covering |
question
Uniform lumen |
answer
Filiform larva |
question
Lumen expanding to posterior bulb |
answer
Rhabditiform larva |
question
Male nematode characteristics |
answer
Males have a copulatory spicule |
question
Ascaris lumbercoides |
answer
10-20cm. Found in Temperate and tropical regions |
question
What conditions may cause a 50% penetration rate? |
answer
Indiscriminated defecation Warmth (20-25 degrees Celsius) Soil is clay or heavy loam High humidity Areas of poor sanitation often have 100% penetration |
question
A single infected ascaris lumbercoides host may have how many parasites a day? |
answer
3-4 up to 1,000 parasites. May produce 2-3 x 10^7 eggs/day/patient Avg 2 x 10^5 eggs/day/female for 6 months-1 year |
question
Ascaris lumbercoides life cycle (Takes 2 1/2 months in hist. 2.5 weeks in the external environment) |
answer
1. Person eats embryonated ovum 2. Larvae escapes covering and travels to small intestine, liver, cardiovascular system, lung, cardiovascular system 3. Then travels to pharynx where they stimulate nerve endings, are swallowed and enter the GI tract 4. Pooped out eventually |
question
Acaris eggs in feces require what? |
answer
Warm moist soil and a 5-8 degree decrease Celsius |
question
Male Ascaris lumbercoides have |
answer
Dorso flexion (Curved tail) |
question
Ascaris infections in children may cause |
answer
Stunted growth |
question
Adult Ascaris worm infection may cause |
answer
High worm burdens, Abdominal pain and intestinal obstruction |
question
Ascaris infections |
answer
Early on the patient is asymptomatic and may see Colic C in children, lactose indigestion in some Lung phase of larval migration Pulmonary symptoms include cough, dyspnea, hemoptysis (Hemorrage from 20mm diamter larvae in 10mm diameter alveolar capillaries) eosinosis pneumonitis, Loeffler's syndrome (also with increased IgG and IgM) |
question
Migrating adult Ascaris worms may cause |
answer
Symptomatic occlusion of the billiary tract, oral expulsion and rectal expulsion |
question
What is the tpyical microscopic procedure for identification of ascaris eggs in the stool? |
answer
1. Collect stool specimen 2. Fix specimen in 10% formalin 3. Concentrate using the formalin-ethyl acetate sedimentation technique (Rictchre) 4. Examine a wet mount of the sediment |
question
What quantitative assessments can be used to identify ascaris eggs? |
answer
Kato-kanz procedure Larvae can be identified in sputum or gastric aspirate during pulmonary migration phase. Formalin fixed organisms for morphology. Adult worms passed in stooll |
question
Enterobius vermicularis |
answer
Most common helminth in temperate regions, aided by close, crowded indoor living. 2.5mm x 0.2 mm (Male) 8-13mm (Female) Habitat is the end of the small intestine/cecum/ beginning of the colon |
question
Describe the egg laying process of enterobius vermicularis |
answer
Female migrates down the colon to the rectum and crosses through the anal sphincter late at night. In the mornin she deposits 10,000-15,000 eggs and then dies |
question
Enterobius vermicularis eggs can survive for how long. How long does it take for full embryonation? |
answer
Eggs survive 2-4 weeks. Embryonation takes 3-5 hours |
question
Enterobius vermicularis life cycle |
answer
1. Person eats ovum 2. Larvae attach to end of small intestine and mature 3. Adult females migrate to periannal region late at night to lay eggs |
question
Enterobius vermicularis patho |
answer
Patient is asymptomatic, puritic (itchy), poor sleep, irritability |
question
Lab dizgnosis fo enterobius vermicularis includes |
answer
Scotch tape test |
question
Hookworms |
answer
Ancyclostoma duodenale (Old worm hookworm) Necator Americanus (New world hookworm. came to America upon arrival of African slaves) |
question
Hookworm life cycle |
answer
1.Filariform larva (infective stage) penetrate skin by crawling up foot and cause allergic reation. 2. It ends up in the circulation where it may enter the CVS because of increased oxygen tension. 3. From the CVS it travels to lungs, trachea and pharnyx where it is swallowed. 4. Matures in small intestine 5. Eggs release in feces and mature in the soil to rhabditiform larvae, then they develop into filariform larvae |
question
When hookworms attach to the small intestine and suck blood. They may cause what? |
answer
Microcytic, normochromic anemia |
question
Hooworm rhabdidiform to filaria takes how long |
answer
2-5 days (2 molts) |
question
Hooworm rhabdidiform compared to filariform |
answer
Rhabdidiform is shorter and more muscular while the filariform is longer and skinnier |
question
Hookworm egg volume |
answer
L x W^2 (Allows for discrimination beetween hookworm eggs and Ter. derminutis eggs) >170,000 u^3 = Ter. derminutis <150,000 u^3 = Hookworm |
question
Some hookworm diagnosis methods |
answer
Find ova in stool Semi-quantitative -Stoll count Hookworm culture -Baerman appartus |
question
Strongyloides stercoralis |
answer
Same as the hookworm but the Female larva is fertilized by the male larva in the lungs |
question
What is the only nematode that can survive its entire life cycle outside of the body? |
answer
Stronglyloides stercoralis |
question
Strongyloides stercoralis patho |
answer
Asymptomatic, rash, symptoms of pneumonia, chrome diarrhea (up to 30 years) Steatorrhoea, dehydration, low-grade fever |
question
Trichuris trichuria |
answer
Known as the "Whip worm" or "Hair tail"Present worldwide but most common in tropical areas |
question
Trichuris trichuria life cycle |
answer
1. Ingest fully embryonated egg 2. Hatches and feeds in vila 3. Matures to adult in the ceum |
question
Trichuris trichuria patho |
answer
Asymptomatic Prolapse of the rectum Anemia Mild eosinophilia |
question
Trichinella spiralis |
answer
Causes trichinosis. Known as the "trichina worm". Can be found encysted in the meat of pork, bear, walrus and others. |
question
Trichinella spiralis patho |
answer
Adults may get cramps, diarrhea, muscle twitching/weakness Larva entering the CVS may cause eosinophilia, and peri-orbilal edema. |
question
Filariodea |
answer
Differ from most other neamtodes by using an arthropod vector. Adults live in the tissue of a vertebrate host Female does not lay eggs but rather is viviparous in delivery |
question
Microfilaria development |
answer
Microfilaria develop in human CVS, then futher develop into the filariform in the vector. |
question
Microfilaria |
answer
Ribbon-like not nucleated to the very end of the organism |
question
Filariform male dies when what occurs? |
answer
After fertilization of the female |
question
Two groups of Filariodea |
answer
Filarids (found in the tropics) and Tissue worms (found in the Western Hemisphere) |
question
Filarids include |
answer
Brugia malayi Wuchereria bruncofti Mansonella ozzardi Dipetalonema perstans Loa loa |
question
Upper extremity elephantitis can be caused by which organisms |
answer
Brugia malayi Wucheria bancrfoti |
question
Tissue worms include |
answer
Onchocerca volvulus Dipetalonema streptocerca |
question
Wuchereria bancrofti (Lower extremity problems) vectors include |
answer
Ades spp Culex spp Anophales spp Mansonia spp |
question
How many microfilaria must the vector pick up to continue an infection in another organism? |
answer
More than 10 If he picks up more than 100 he dies |
question
Wuchereria bancrofti symptoms |
answer
Tenderness Swelling Fever Known as Munu |
question
Brugia malayi |
answer
Upper extremitites |
question
Mansonella perstans |
answer
Adults found in peritoneal cavity or lungs |
question
Mansonella ozzardi |
answer
Vector Biting Midge "Blackfly" |
question
Trematodes Class distinction |
answer
Class Turbellaria -most are free-living, no human parasites Class Trematoda -All are parasitic "flukes" |
question
Trematoda can be monogenea which means |
answer
They have 1 host and are ectoparasites of fish |
question
Trematoda can be digenea which means |
answer
They have 2 or more hosts and are ectoparasites of reptiles and birds |
question
Trematoda characterstics |
answer
Dorsoventrally flat, do not have coelom, have an incomplete digestive tract and most are hemaphroditic and self fertilizing |
question
Life cycle of Trematoda |
answer
question
Schistoma spp |
answer
Only medically significant trematode to not be hermaphroditic, thrive in ditches, cause problems at places such as the great dam at Aswan, Egypt |
question
Schistosoma mansoni |
answer
Vectored planorbiadae (Snail family) |
question
Schistosoma life cycle |
answer
question
Clonorchis sinensis |
answer
Metacercaria form is encysted in fish muscle tissue. Clonorchis sinensis is endemic in Kore, China. Live in bilary ducts and the presence of adults can cause inflammationa and intermittent obstruction |
question
Clonorchis sinensis patho acute phase |
answer
Ab pain, nausea, diarrhea |
question
Clonorchis sinensis patho chronic infection |
answer
Cholangitis Cholelithiasis Pancreatitis |
question
Opsithurcis/ clonorchis ultrasound will show |
answer
Multiple liver absesses and cystic or "mulberrry-like" dilations |
question
Metagonimiasis |
answer
Far East, Siberia |
question
Metagonimiasis patho |
answer
Diarrhea Colicky ab pain Migration of the eggs to extraintestinal sites such as the heart and brain |
question
Heterophyes heterophyes |
answer
Egypt, Middle East. Cause diarrhea and colicky ab pain |
question
Heterophyes heterophyes life cycle |
answer
question
Cestoda |
answer
"Tapeworms".Consist of a scolex (head) and a strobula (proglottid). All are hermaphroditic. Capable of self fertilization from one proglottid to the next |
question
Cestoda life cycle |
answer
1. Person ingests organism which was encysted in the muscle tissue of fish. 2. Scolex attaches to small intestine and sucks in nutrients 3. Proglottids begin to form 4. Eggs formed in feces 5. Eggs embyryonate in the water 6. Coracidia hatch from eggs and are ingested by copapods 6. Larvae forms inside copapods 7. Fish eat copapod and plerocercoids form in the fish muscle. |
question
Cysticercus larva |
answer
Found in cow and pigs |
question
Procercoid larva |
answer
Found in cepepod |
question
Piercercoid larva |
answer
Fish |
question
Cysticercoid larva |
answer
Insect |
question
Acetabulum type |
answer
Vinegar cup -Rostellum with or without hooklets |
question
Bothria type |
answer
Multiple bothria |
question
Raised, armed rostellum |
answer
Taenia pisiformis |
question
Cestode Female reproductive organs include |
answer
Ovary Oocyte Uterus Uterie pore Vagina |
question
Cestode Male reproductive organs include |
answer
Testes |
question
Dibothriocephalus latus |
answer
Fish tapeworms, broad tapeworms. Distinguishing features include the uteran pore and multiple genital pores. 2 "lip" type flaps with two sucers at the end of the scolex |
question
Dibothriocephalus latus life cycle |
answer
1. Human ingests pleurocercoid which was encysted in muscle tissue of fish 2. Scolex attaches to intestine and matures to an adult 3. Unembryonated eggs passed in the feces 4. Once in water, eggs are embryonated and referred to as Hexacanth embryo or onchosphere 5. Matures into caracidium and is ingested by a copapod which is then eaten by a fish |
question
Dibothriocephalus latus patho |
answer
Asymptomatic, B12 deficiency (if the scolex attaches to the proximal jejunum selectively absorbs B12 Patient will have pernicious anemia and spargenosis |
question
Non-human (usually) species invades |
answer
All human tissues and are "ectopic" and migrate to tissue into a sporganum. Often caused by applying tissue (frog, snake) to open wound |
question
Lab diagnosis for Dibothriocephalus latus |
answer
Look for opercular knob |
question
Cyclophyllideas |
answer
Taenia solium Taenia saginata |
question
Taenia solium |
answer
Common in the U.S. comes from undercooked pork. 1. Intermediate host, 1 adult/Primary host. 4-7 metes. 1 per person. Rasied, armed rostellum |
question
Taenia saginata |
answer
"Beef tapeworm". Frequent in the U.S. 8-15 meters. Usually no more than 3 per patient. Stump rostellum. 6.0 x 10^8 ova/yr/scolex |
question
Taenia lifecycle |
answer
1. Humans ingest scolex in pig/cow muscle tissue 2. Scolex attache to small intestine and matures to adults 3. Eggs or gravid proglottids are passed in feces into the environment. 4. Cows and pigs eat infected grass |
question
Proglottids from taenia species can do what once they are in the GIT? |
answer
Crawl out of the GIT, creep along the ground and disintegrate, spreading their eggs. |
question
Taenia solium patho |
answer
Asymptomatic Vague ab pain Hunger/drowsiness Chronic indigestation |
question
Taenia saginata patho |
answer
Asymptomatic. Cysticercosis. Often called custocarcis boving. |
question
Lad diagnosis of Taenia spp |
answer
Find ova or proglottid in feces. Examine proglottid and use 10%EtOH slowkill to prevent the uterus from contracting |
question
Echinococcus granulosus |
answer
Causes hydatid cyst disease Dog tapeworm Larval stage (cyst) infects humans. Occurs in cattle, sheep and goat raising countries |
question
Echinococcus granulosus life cycle |
answer
1. Eggs passed in dog feces 2. Ingested in humans and travel to small intestine 3. Lodge in the lungs |
question
Hymenolepis diminuta |
answer
Rat parasite with a peach pit ova |
question
Hymenolepis nana |
answer
Rat parasite, patients are often asymptomtic |
question
Dipylidium caninum |
answer
Dog parasite |
question
General intestinal amoeba life cycle |
answer
1. Person eats infective cyst in contaminated food or water. 2. Cyst excysts in colon and reproduces asexually. 3. Infective cyst exits in formed stool, troph passes in liquid or soft stool and intestinal wall erosion (by ent. histolytica which leads to liver via the circulatory system and then to a hepatic abscess. |
question
Leishmania spp life cycle |
answer
1. Sandfly bites human and regurgitates promastogote into the person. 2.Promastigota transforms into an amastigote and multiplies intracellularly. 3. Amastigote is then ingested by sand fly and transformaed into promastigote in the midgut of the fly. |
question
Which organism has a safety pin fibril |
answer
Chilomastix mesnili |
question
Patient diagnosis process |
answer
1. Patient presents with signs, symptoms and appearance. 2. History and physical 3. Physician created Rule out List (Differential diagnosis) 4. Objective information. Orders lab tests, etc 5. Diagnosis 6. Therapy 7. Assessment of post treatment progress |
question
Paragonumus westermani Life cycle |
answer
1 Person consumes metacercariae from inadequately cooked crustaceans 2. Excysts in duodenum 3. Entitiy develops into and adult fluke in the lungs 4. Expel organism in sputum or feces 5. Travels to water and embryonates. Hatches and penetrates. Can be obtained by eating raw crabs or fish |
question
Paragonimus kellicotti |
answer
Endemic to North America Causes pain and severe coughing, hemoptysis |
question
Fasciola (Found wherever sheep and cattle are raised) Life cycle |
answer
1. Eggs released in stool and become embryonated in the water. 2. Eggs release miracidia which invade a snail host 3. Parasite matures (sporocyst, rediae, cercariae 4. Cercariae escape from snail and encyst as metacercariae on aquatic vegetation. 5. Humans ingest the plants and the metacercariae excysts in the duodenum 6. Travel to the biliary ducts where they mature into an adult fluke |
question
Localized dermatitis caused by what parasite |
answer
Schistosoma cercarial penetration |
question
Parasite first found in Egyptain mummies |
answer
Schistosoma |
question
Cercarial dermatitis |
answer
Caused by metacercariae of schistosoma at skin penetration, causes petechial hemorrhage |
question
Acute schistosomiasis |
answer
Caused by schistosoma, causes katayama fever, looks like serum sickness, could cause hepatosplenomegaly, lymphadenopathy and eosinophilia |
question
Schistosoma haematobium |
answer
Can cause pulmonary issues |
question
Schistosoma can cause |
answer
Bacterial complications with mostly salmonella spp Circulating immune complexes. |