Epidemiology Test Questions – Flashcards
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Presence and multiplication of another organism usually a microbe in the body of the host
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Colonization
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A _ is an organism capable of supporting the nutritional and physical growth requirements of another
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host
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One organism, the host, is injured through the activities of the other, the parasite
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Parasitism
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The detrimental colonization of a host by a foreign organism
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Infection
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Ability to invade host
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Infectivity
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Infectivity formula
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Number infected / Number susceptible x 100
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Ability to cause disease
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Pathogenicity
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Pathogenicity formula
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Number with clinical disease / number infected x 100
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Ability to cause disease or death
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Virulence
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Virulence formula
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Number of deaths / number with disease x 100
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These are highly virulent; rarely found without disease to host
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Pathogens
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Produce disease when the health and immunity of the host have been severely weakened by illness, malnutrition, or medical therapy.
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Opportunistic pathogen
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Parasites that can't survive outside of a host
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Obligate parasites
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May exit in a free-living state or as commensal, and may become parasitic under certain conditions.
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Facultative parasites
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These types of parasites live inside the host
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Endoparasites
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Parasites that live on the surface of the host
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Ectoparasites
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The number of new cases of an infectious diseases that occur within a defined population
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Incidence
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The number of active cases at a given time
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Prevalence
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Disease that has a relatively stable and expected incidence and prevalence within a geographic area
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Endemic
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An abrupt and unexpected increase in the incidence of disease over endemic rates.
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Epidemic
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The spread of disease beyond continental boundaries
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Pandemic
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Where organisms can live, accumulate or persist outside of the host of interest; could be another organism or the inanimate environment
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Reservior
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Inanimate objects/materials by which organisms get from one host to another; includes water, food, objects and biological products
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Vehicles
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Living organisms bringing infectious organisms to a host
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Biological Vector
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Microbes do not multiply in the vector. Ex: biting insects infected with the infectious organism
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Mechanical Vector
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Microbes must propagate in the vector before they can be transmitted to a host
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Biological Vector
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Name the two types of human reserviors
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Acute clinical cases Carriers
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Name the four types of carriers
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Incubatory Inapparent infection Convalescent Chronic
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These types of carriers begin transmission before full blown disease appear
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Incubatory carrier
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This is a type of infection that doesn't develop the disease but are able to transmit
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Inapparent infections
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Continue to carry infection after recovery
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Convalescent
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This is a type of carrier that continues to harbor infection years after recovery
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Chronic carrier
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Name the two types of contact transmission
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Direct Indirect
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Name the three types of vehicle transmission
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Airborne Waterborne Foodborne
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Name the two types of vector transmision
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Mechanical Biological
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Name the four types of portal entry
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Penetration Direct contact Ingestion Inhalation
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What type of transmission is commonly associated with STDs?
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Direct contact
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A mother can spread an infection to a child through these two types of transmission
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Vertical Congenital
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What are the TORCHES infections?
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Toxo Other (Varicella, Step B) Rubella Cytomegavirus Herpes Syphilis
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The severity of congenital defects associated with infection are dependent upon _ _ of the fetus when transmission occurs
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gestational age
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What is the most efficient form of transmission?
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Ingestion
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An object capable of transmitting an infection
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Fomite
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A term desctibing an opportunistic infection acquired from host's own microflora source of infection
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Endogenous
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External environment such as water, food, soil, or air source of infection
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Exogenous
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Mother to child during gestation source of infection
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Congenital
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Mother to child during birth source of infection
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Perinatal
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Animals to human source of infection
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Zoonoses
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Term describing a source of infection from vectors
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Vector borne
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Name the two terms for specific locations where infections can be acquired
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Nosocomial Community
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Health care facility source of infection
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Nosocomial
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Outside health care facility source of infection
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Community
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Collection of signs and symptoms expressed by the host during the disease course
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Symptomology
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Symptomology is also referred to as these two things
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Clinical picture Disease presentation
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Outwards expression of the interaction between invading organisms and the retaliatory inflammation and immune responses of the host
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Symptomology
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A group of symptoms shared by a number of diverse infectious diseases
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Nonspecific
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Symptoms that directly reflect site of infection
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Specific
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Obvious
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Overt
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Type of infection needing lab testing to detect
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Covert
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Name the five stages of the disease course
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Incubation Prodromal Acute Convalescent Resolution
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Stage of active replication of a pathogen
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Incubation
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There are _ symptoms in the incubation stage
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no
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This stage can have no pronounced clinical presentation or the initial symptom presentation of disease
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Prodromal
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This stage has the most impact of the infectious process
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Acute
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This stage is marked by the rapid proliferation and dissemination of the pathogen
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Acute
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In this stage, symptoms are pronounced and more specific to the pathogen and site of infection
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Acute
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This stage is marked by the containment of the infection
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Convalescent
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This stage is marked by the progressive elimination of the pathogen
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Convalescent
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This stage is marked by the repair of damaged tissue as well as the resolution of symptoms
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Convalescent
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This stage is marked by the total elimination of a pathogen and there are no longer and residual signs of infection
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Resolution
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In this type of infection, symptoms may be continuous or sporadic for months or years without a convalescent phase
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Chronic
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In this type of infection, progress from infection to resolution without clinically apparent symptoms
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Subclinical
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In this type of infection, disease existing, without marked symptoms, but ready to become active upon some slight occasion
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Insidious
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In this type of infection, there is an abrupt onset of symptoms with little or no prodromal
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Fulminant
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A term describing an infection that has disseminated from the site of primary infection (usually by the circulatory system) to involve other locations and organ systems
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Systemic
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Name three prominent places of localized infection
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Respiratory GU GI
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Substances or products generated by infectious agents that enhance their ability to cause disease
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Virulence factor
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Name the four main types of virulence factors
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Toxin Adhesion Evasive Invasive
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Substances that alter or destroy the normal function of the host or host's cells
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Toxin
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Toxins are primarily produced by _ pathogens
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bacterial
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Name the two main types of toxins
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Endotoxin Exotoxin
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Proteins released from the bacteria cell during growth would be classified as what type of toxin
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Exotoxin
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This is another name for bacterial exotoxins that produce vomiting and diarrhea
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Enterotoxin
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These toxins are non-protein, complex molecules composed of lipid and polysaccharides that has no enzymatic activity
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Endotoxin
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Endotoxins are found in the _ _ of _ _ _
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cell wall, gram negative bacteria
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_ is not released from the bacteria during growth
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Endotoxin
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Endotoxins can cause _ _
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endotoxic shock
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Small amounts of endotoxins can produce these five symptoms
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Clotting Bleeding Inflammation Hypotension Fever
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_ is disease in individuals with weakened immune systems
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Commensals
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The five evasive factors are these
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Superficial entry Internal environment entry Antibody evasion Cell immunity evasion Alternating life cycle
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The study of the distribution and determinants of disease or health-related states or events in specified populations and the application of this study to the control of health problems
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Epidemiology
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Term describing how often a disease causes death
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Mortality
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Term describing the relative incidence of disease
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Morbidity