Chapter 11 Biology Questions – Flashcards

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question
What controls the way in which a zygote differentiates?
answer
Selective genes are turned on and off, depending on the fate of the cell.
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Anhidrotic ectodermal dysplasia is an X-linked disorder that results in the absence of sweat glands. How would this condition be manifested in a heterozygous female?
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She would have a random pattern of tissue with and without sweat glands.
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When are DNA molecules the least tightly coiled?
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S phase of interphase
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After translation is complete, the insulin polypeptide is activated by _____.
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the cutting of the initial translation product to yield two shorter chains joined together by sulfur linkages
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In embryonic mice, a homeotic gene controls development of the neck, which includes the larynx and thymus. If this gene were deleted, a full-term mouse would show _____.
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lack of development of the larynx and thymus
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Cloning experiments with differentiated root cells from carrots revealed that _____.
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an entire plant can grow from a differentiated cell
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Since the first animal was produced using a fully differentiated cell, a number of observations have been made. Which of the following statements is true in regard to reproductive cloning?
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Cloned animals often develop chronic conditions that are usually only associated with old age.
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Stem cells could be immensely important in the treatment of which of the following conditions?
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spinal cord injuries
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Proto-oncogenes have the potential to become oncogenes. Which of the following is most likely to lead to cancer?
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a mutation that causes the proto-oncogene to become overactive
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The Rb protein prevents mitosis by inhibiting cells from entering S phase. Human papillomavirus (HPV) is thought to inhibit the action of the Rb protein in cervical epithelial cells. What would be the effect of cervical cells being infected with HPV?
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The mitotic rate would increase.
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In humans, the most common cancer is _____.
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lung cancer
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In prokaryotes, a group of genes with related functions that are organized and regulated as a group is called ________
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an operon
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Tryptophan is placed into a culture of E. coli cells. As a result, the bacterial cells switch off transcription of genes involved in the production of tryptophan because the amino acid binds to the __________.
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repressor
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The gene for human growth factor is inserted into the E. coli lactose operon so that it replaces the structural genes with the gene for human growth factor. What substance must be added to the bacterial culture so that it produces human growth factor?
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lactose
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Cells become specialized by a process known as ___
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differentiation
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Anhydrotic dysplasia is a genetic disorder in humans that results in the absence of sweat glands in the skin. Some men have this defect all over their bodies, but in women it is usually expressed in a peculiar way. Women with this disorder typically have small patches of skin with sweat glands and other patches without sweat glands. This pattern of sweat-gland distribution can be explained by _____.
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X chromosome inactivation
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Histones are _____.
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proteins around which DNA is coiled
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In eukaryotes, gene expression is regulated mostly by _____.
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controlling the transcription of genes
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MicroRNA (miRNA) functions by binding to _____ and blocking translation.
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complementary mRNA sequences
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Gene expression can also be controlled after the mRNA molecule has left the nucleus. These mechanisms may include the _____.
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breakdown of RNA
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It is possible for a cell to make proteins that last for months; for example, hemoglobin in red blood cells. However, many proteins are short-lived and may be degraded in days or even hours. Why do cells make proteins with such a short life?
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This enables cells to control the amount of protein present.
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In fruit flies, there are molecules in the egg that determine the future head and tail ends of the animal. What occurs when mRNA from the head end of an embryo is injected into the tail end of an early embryo?
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Some head structures develop at the tail end; the head end develops normally.
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A signal transduction pathway activates a transcription factor that responds by _____.
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initiating mRNA synthesis
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Clones are derived _____.
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from a single ancestor cell
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Experiments involving _____ have demonstrated that differentiated cells contain all of the genetic information found in undifferentiated cells.
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nuclear transplantation
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In frogs, when the nucleus of an intestinal cell of a tadpole is transferred to an egg whose nucleus has been removed (nuclear transplantation), some of the eggs will develop into normal tadpoles. This demonstrates that _____.
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these cells have retained all of their genetic potential
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Stem cells could be immensely important in the treatment of which of the following conditions in the near future?
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spinal cord injuries
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Embryonic stem cells differ from adult stem cells because they _____.
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can differentiate into all cell types
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A proto-oncogene is a normal gene that can change into an oncogene. Oncogenes are potentially lethal genes that can cause cancer. Why do cells continue to maintain proto-oncogenes?
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Proto-oncogenes are necessary for normal control of cell division
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Which of the following statements best describes cancer cells?
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Normal controls over cell division have been altered.
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Which of the following would be most likely to lead to cancer?
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generation of multiple copies of a proto-oncogene and inactivation of a tumor-suppressor gene
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Most human cancers are _____.
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caused by the accumulation of mutations
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Exposure to which of the following substances increases cancer risk?
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ultraviolet light exposure
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In humans, the agent responsible for the greatest number of cancers is _____.
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tobacco
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