Micro terms 4 – Flashcards
Unlock all answers in this set
Unlock answersquestion
simple structure that lacks a nucleus |
answer
prokaryotes |
question
the bacteria that causes tetenus |
answer
clostridium tetani |
question
spherecal and ovoid bacteria are called |
answer
cocci |
question
both types of rods (bacteria) is called |
answer
bacilli |
question
spiral shaped bacteria are called spirilla or |
answer
spirillum |
question
cooci form two cell arrangements called |
answer
diplocci |
question
streptococcus pneumoniae causes |
answer
resppiratory infections |
question
some bacteria are refered to as _____________ which means they can change shape |
answer
pleomorphic |
question
bacteria can be classified by genus and species. further classification of bacteria can be based on |
answer
size, shape, and arrangement |
question
the gram stain can be used to classify most bacteria into foru major groups |
answer
gram-positive, gram-negative, gram-variable, and gram-nonreactive |
question
can be used to identify bacteria shapes and in particular spirochetes |
answer
the negative stain |
question
refers to whether or not a bacterium that is first stained and then washed with acid retains its staining dye |
answer
acid-fast |
question
stainingis used to make organisms |
answer
microscopically visible |
question
there are 2 types of dye: simple stains which uses _______- differiental dye which uses ________ |
answer
one dye more than 1 dye |
question
is used to classfiy bacteria on the basis of their cell wall structure |
answer
the gram stain |
question
several stains such as the capsule, flagella an d endospore stains, are used to identify structures associated w/ the |
answer
bacterial cell wall |
question
WHY IS THIS IMPORTANT?You have to understand ___________ for success in studying microbiology in general and the process of infection in particular. ?Understanding the relationship between ____________ is required for understanding the processes of infection and disease. |
answer
why is CELL STRUCTURE AND HOST-PATHOGEN RELATIONSHIPS important |
question
Biologists classify microorganisms by their __and ____ name |
answer
genus and species |
question
An example is Clostridium tetani. Clostridium is the _______ and tetaniis the _______. |
answer
genus and species |
question
are the smallest living organisms and are microscopic. ?are immensely diverse and very successful organisms that colonize all parts of the world and its inhabitants. ? are referred to as pathogens if they cause disease. |
answer
bacteria |
question
Bacteria can be of different shapes, sizes, and arrangements. ?The most common are the following |
answer
Bacillus (rod shaped) ?Coccus (circular shaped) ?Spirilla (spiral shaped) |
question
Bacillus (rod shaped) ?Coccus (circular shaped) ?Spirilla (spiral shaped) positive stain negative stains simple stain differential stains |
answer
stains the organism stains the background stain using one color stain use more than one color |
question
takes advantage of the differences in the cell walls of bacteria. process divides bacteria into four major groups: ?Gram-positive ?Gram-negative ?Gram-variable ?Gram nonreactive |
answer
THE GRAM STAIN |
question
stains the background surrounding encapsulated bacteria. ?It can be used to identify the presence of a capsule (important in virulence factors) as the background staining makes the capsule highly visible. |
answer
The negative technique |
question
The flagella stain identifies the presence of flagella, which are used for motility. ?Motility is important for infection as it allows the invading organisms |
answer
to move from the initial infection site |
question
This stain is used to detect Mycobacterium species such as M. tuberculosis or M. leprae. ?These organisms have mycolic acid (a virulence factor) in their cell walls, making the cell wall difficult to penetrate |
answer
THE ZIEHL-NEELSEN ACID FAST STAIN |
question
THE ZIEHL-NEELSEN ACID FAST STAIN uses heat as part of the process to break down the ___________ and permit the entry of the stain. ?It is called _________ because positive cells retain color even after washing with acid. Microbiology: A Clinical Approach, by Tony Srelkauskas© Garland Science Approach © Garland Science THE ZIEHL-NEELSEN ACID FAST STAIN © CDC/ Dr. George P. Kubica ISBN: 978-0-8153-6514-3 Microbiology: A Clinical Approach, by Tony Srelkauskas© Garland Science Approach © Garland Science THE ENDOSPORE STAIN ?Endospores are small, tough, dormant structures that can form in certain bacteria. ?Heat is needed to make the endospore wall permeable to the stain. |
answer
mycolic acid acid fast |
question
are small, tough, dormant structures that can form in certain bacteria. ?Heat is needed to make their permeable to the stain. |
answer
ENDOSPORE |
question
HOST-PATHOGEN RELATIONSHIPS for the pathogen the interabtions depend oh what 3 things |
answer
The pathogen’s ability to evade or overcome the host’s defense ?The pathogen’s ability to increase in numbers ?The pathogen’s ability to identify transmission mechanisms to new hosts. |
question
HOST-PATHOGEN RELATIONSHIPS ?For the host, the interactions depend on: |
answer
The host having useful functioning defenses ?The host’s susceptibility to infection ?The degree of compromise found within the host immune system |
question
infection is a matter of survival. ?The human body contains huge numbers of harmless bacteria. ?It interacts with enormous numbers of bacteria outside the body. |
answer
for the pathogen |
question
In most cases, the interactions between the body and the bacteria cause no harm. ?Some bacteria have a ___________ with the host. ?In these cases, the bacteria provide something beneficial to us and we provide something beneficial to them. |
answer
mutualisticrelationship |
question
pathogens cause infection by taking advantage of a hosts’ increased susceptibility of infection |
answer
oppurtunitic |
question
charaacteristics are as follows: ?They cause disease in healthy individuals. ?They include viruses and bacteria. |
answer
primary pathogens |
question
Characteristics: ?They have evolved mechanisms that can overcome host defenses. ?Once inside, they can multiply rapidly. ?Some are restricted to humans |
answer
primary pathogens |
question
Successful infection requires the following from a pathogen |
answer
The ability to multiply in sufficient numbers ?The ability to transmit to new hosts. |
question
Symptoms of certain infections can provide transmission mechanisms through: ?_____ transmits respiratory infections. ?_______ transmits digestive infections. |
answer
coughinh diarherra |
question
Infections that kill too quickly inhibit |
answer
transmission |
question
Pathogens must be able to accomplish the five requirements for infection: |
answer
?Entry (getting in) ?Establishment (staying in) ?Defeat the host defenses ?Damage the host ?Be transmissible |
question
refers to how harmful a pathogen is to the host. ?depends on genetic factors of the pathogen. ?These genetic elements are often turned on only in the host. |
answer
virulence |
question
Pathogens carry virulence genes in clusters called __________. ?These can be located on plasmids. ?Plasmids can be transferred between cells. |
answer
pathogenicity islands |
question
Organisms sense their environment using special sensing proteins is based on population densities. ?Certain genes are only turned on when there are enough cells present: ?An example of this is enterotoxin production in Salmonella |
answer
quorum sensing |
question
Bacteria can grow in aggregated assemblies within their host. These assemblies are called |
answer
biolfilms |
question
are clinically important because: ?They can capture and retain nutrients (allowing continued growth). ?They impede uptake of antibiotics and disinfectants. ?They inhibit phagocytosis |
answer
biofilms |
question
is the barrier between the inside and the outside of the cell, it must be breached if pathogens are to gain entrance. ?It contains specific receptors used by viruses to attach to host cells. ?It can become the envelope for certain types of viruses. |
answer
EUKARYOTIC CELLS: the Plasma Membrane |
question
is involved in a variety of infections. ?It has a major role in viral infections. ?Many viruses replicate in the host cell ______ |
answer
cytoplasm |
question
is involved in how cells are joined together to form tissue. Many pathogens use the ________ as part of the infection process. ?Shigella use microfilaments to move laterally between cells of the intestine. |
answer
cytoskeleton |
question
Pathogens can attack the _______ and destroy their trapping capability. ?In some respiratory diseases, such as pertussis (whooping cough), the pathogens (in this case Bordetella pertussis) attach to host ______ cells as an initial part of the infection |
answer
cilia ciliated |
question
are very important in viral infections but not by choice. ?The virus takes over the host cell _______ function. ?It is then used only to make new virus |
answer
Eukaryotic ribosomes |
question
EUKARYOTIC CELLS: Role of the ER & Golgi Apparatus in infection |
answer
are involved in the biosynthesis and assembly of viruses. |
question
is also involved in the adaptive immune response to infection |
answer
the ER |
question
fuse with cellular vesicles. ?They are responsible for destroying foreign materials that enter the cell. ?They also act in recycling host cell components |
answer
lysosomes |
question
participate in the degradation of proteins. ?They are also involved in recycling protein components. |
answer
EUKARYOTIC CELLS: Proteasomes |
question
of the host cell is important in many infections, particularly those caused by DNA viruses. ?Copies of the viral DNA are made in the __________. ?These copies are then moved into the cytoplasm to be used for the construction of new virus molecules. |
answer
EUKARYOTIC CELLS:The Nucleus |
question
There are three ways that endocytosis operates within a cell: |
answer
Pinocytosis ?Phagocytosis ?Receptor-mediated endocytosis |
question
Many pathogens enter the host cell through the formation of ________. ?This method provides protection for the pathogen from the host immune response. ?Some pathogens bind to host cell receptors that trigger ________. This is particularly true of viruses |
answer
vesicles endocytosis |