Test Questions on Bacteria – Microbiology – Flashcards with Answers

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question

Gram +

Catalase +

Coagulase +

Cocci

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S. aureus
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gram +

Catalse +

Coagulase -

Cocci

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Staph epidermidis
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This bacteria has M protein, capsule, is B-hemolytic

Causes: Pharyngitis, Scarlet fever, Toxic Shock

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Group A Strep
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This bacteria is an important cause of neonatal meningitis

It is a gram+ cocci, B-hemolytic

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Group B strep (Streptococcus agalactiae)
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This gram + cocci is catalase and coagulase -

Causes tooth decay and heart damage

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Viridans Streptococci
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Gram+ diplococci, alpha-hemolytic

Is an important cause of CA-pneumonia

Most common cause of bacterial meningitis in adults

Optochin sensitive

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Streptococcus pneumoniae
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Gram+ pairs/short chains, often MDR

Causes nosocomial infections, UTI, bacteremia

Part of normal bowel flora

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Enterococcus
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Gram+ spore forming bacillus

Causes gas gangrene, cellulitis, food poisoning

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Clostridium perfringens
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Gram+ anaerobic spore forming

Can be foodborne, also found in soil/water

has A-B toxin preventing ACh release

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Clostridium botulinum
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gram + anaerobic bacillus

spores have "drumstick" appearance

found in soil

A-B toxin prevents release of GABA/glycine

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Clostridium tetani
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Gram+ spore forming bacillus

causes diarrhea, pseudomembranous colitis

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Clostridium difficle
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Gram+, spore forming bacillus w/capsule

transmision: animals --> human

used as bioterror weapon

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Bacillus anthracis
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Gram+ spore forming bacillus

Causes food poisoning (rice)

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Bacillus cereus
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Gram+ rod, aerobic

 

causes: exudative pharyngitis --> gray fibirinous psuedomembrane

 

A-B toxin inhbitis protein synthesis by ADP ribosylation of EF2

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Corynebacterium diphtheriae
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Gram+ rod with ENDOTOXIN (LPS), motile

catalse +, B-hemolytic

facultative intracellular organism

can live at a wide range of temps

causes neonatal meningitis

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Listeria monocytogenes
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Gram+ rods/filaments, anaerobic

causes chronic granulomatous lesions

Sulfur granules

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Actinomyces israelii
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gram + aerobe, acid fast

causes: bronchial pneumonia, cutaneous infection

 

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Nocardia
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gram+, acid-fast, aerobic bacillus

primary- asymptomatic lung infection

secondary- caseating granulomas, night sweats, weight loss, productive cough w/blood

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Mycobacterium tuberculosis
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Gram+, acid fast

cannot be grown in culture

involves skin, nerves, eyes, and testes

manifestation depends on if body chooses Th1 or Th2 response

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Mycobacterium leprae
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gram - rod, lactose -

causes gastroenteritis, enteric fever

Virulence factors: hemolysin, Vi, endotoxin

 

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Samonella typhi or paratyphi
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gram - rod, lactose -, motile

causes: self-limiting nausea, vomiting, diarrhea

zoonotic, NOT invasive

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Samonella typhimurium/enteriditis
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gram - rod, lactose -, NON-motile

very small inoculum

causes: cramps, diarrhea, fever, bloody stool

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Shigella
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gram - rod, lactose -

zoonotic

invasive, type III secretion of Yops proteins

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Yersinia

pestis --> bubonic plague

entercolitica --> enterocolitis

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gram -, lactose +

grows on EMB and MacConkey Agar

3 major antigens: O, K, and H

cuases: diarrhea of various types

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Pathogenic E.coli

ETEC- enterotoxigenic --> Traveler's diarrhea

EPEC-enteropathogenic --> infant diarrhea

EIEC -enteroinvasive --> bloody diarrhea

EHEC-enterohemorrhagic --> bloody diarrhea

EAEC-enteroaggregative --> infant diarrhea

DAEC-diffusely aggregative --> watery diarrhea

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gram - rod, lactose +

red currant jelly

causes CA-pneumonia

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Klebsiella pneumoniae
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gram-, lactose - rod, urease +

"swarming" on plates

causes: UTIs and kidney stones

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Proteus mirabilis
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gram-, lactose +

red/pink pigment

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Serratia marcescens
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gram -, lactose + rod

causes: nosocomial pneumonia, UTI, bacteremia, meningitis

resistant to 3rd generation cephalosporins

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Enterobacter and Citrobacter
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gram -, cytochrom oxidase +

causes: skin infections in burn patients, UTIs, external otitis, endocarditis in drug users

has pyocyanin, grape-like odor

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Psuedomonas aeruginosa
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gram -, anaerobic bacillus

Causes: intra-abdominal infections after surgery, wound, perforation, ruptured appendix

usualy part of a mixed infection

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Bacteroides fragilis
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gram -, curved rod, single flagellum

causes watery diarrhea

toxin increases cAMP, blocks absorption of Na, promotes secretion of Cl --> rice water stools

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Vibrio cholerae

 

also V. parahemolyticus and V. vulnificus

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gram -, curved rod, single polar flagellum

MOST COMMON cause of bacterial gastroenteritis

zoonotic

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Campylobacter jejuni
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gram -, curved rod, single flagellum, urease+

causes: gastroenteritis, duodenal ulcers, gastric carcinoma/lymphoma

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Helicobacter pylori
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gram - diplococcus, encapsulated

grows on Thayer-Martin chocolate agar

causes: meningitis, meinigococcemia

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Neisseria meningitidis
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gram- diplococci, no capsule

causes: urethritis, PID

is an STD

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Neisseria gonorrheae
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gram-, oxidase +, aerobic diplococci

causes: otitis media, COPD

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Moraxella catarrhalis
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gram -, coiled spiral shape

STD

test for it using VDRL, FTA-ABS

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Treponema pallidum aka Syphilis
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gram - spirochete

erythema migrans --> migrating oligoarthritis

transmission via tick or body louse

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Borrelia

burgdorferi --> lyme disease

recurrentis --> relapsing fever, severe, less relapses

hermsii --> replasing fever, mild, more relapses

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gram - spirochete

causes: flu-like symptoms, Weil's syndrome

Transmission: rodent/animal urine

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Leptospira
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gram - rod

causes Cat scratch fever

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Bartonella henselae
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gram - rod

causes Trench fever in 5 day intervals

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Bartonella quitana
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gram - rod

transmitted by sandfly

causes Orroya fever

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Bartonella bacilliformis
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gram -, mostly aerobic

type B and non-typeable strins

causes: pneumonia, meningitis, cellulitis, arthritis

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Haemophilus influenza
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gram - aerobic bacillus

intracellular, requires iron and cysteine

causes: pneumonia

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Legionella pneumophilia
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gram- cocco-bacillus

causes:severe paroxysmal coughing

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Bordetella pertussis
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gram- cocco-bacillus

causes: undulant fever w/malaise/chills

transmission: unpasteurized milk, direct contact w/animals carrying strains

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Brucella
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gram - coccobacillus, encapsulated

causes Tularemia (glandular fever)

Transmission: tick, cat/rabbit

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Francisella tularensis
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gram - cocco-bacillus

causes: localized, streaky cellulitis

transmission: cat scratch or bite

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Pasteurella multicoda
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gram - with LPS, obligate intracellular

causes Rocky Mountain Spotted Fever

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Rickettsia rickettsii
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Smallest free-living organism

NO cell wall

causes: atypical/walking pneumonia

"fried egg" morphology

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Mycoplasma
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obligate intracellular organsim

replicates in phagolysosomes

causes Q Fever

transmitted from animals

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Coxiella burnetii
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obligate intracellular

has Elemntary and Reticulate body forms

is an STD

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Chlamydia trachomatis
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This gram positive rod can cause granulomatosis infantisepticum in a neonate
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Listeria monocytogenes
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This bacteria causes traveler's diarrhea
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Enterotoxigenic E.coli (ETEC)
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This type of E.coli expresses the phage transduced Shiga toxin
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Enterohemorrhagic E.coli (EHEC)

 

O157:H7 is best known serotype

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