Case 4: Trousseau syndrome – Flashcards
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Define trousseau syndrome
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Association between visceral cancer and excessive blood coagulation
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3 mechanism of Trousseau syndrome 1. Hypoxia of tumor... 2. tumor secretes... 3. tumor secretes...
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(1) Hypoxia of tumor activates coagulation cascade (2) Carcinoma secretes mucins, which interact with P, L-selectins (3) Tumor secretes tissue factor (TF), inducing fibrin formation
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Clinical presentation of Trousseau syndrome
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(1) DVT (2) PE (3) chronic DIC (4) arterial thrombosis
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Visceral cancers often cause Trousseau syndrome, esp....
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(1) Lung cancer (2) Pancreatic cancer
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Which marker is used to stain pancreatic cell?
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S100P
