Tumor Markers mnemonics – Flashcards
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Alfa fetoprotein (AFP)
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Henry Thought Liver Not Very Good = Hepatocellular, Testicular, Liver Cirrhosis, Neural Tube Defects, Viral Hepatitis, GI tract malignancies
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CA-125
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Oh Every Pretty Lady Has Painful Periods = (Ovarian, Endometrial, Pancreatic, Liver, Hepatitis, Pregnancy, Peritonitis)
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CA 19-9
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Baby Boys Can't Play House - (Breast, Biliary, Colorectal, Pancreatic, Hepatic)
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Carcinoembryonic Antigen (CEA)
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Creepy Guys Only Pay Pretty Busty Loose Ladies (Colorectal adenocarcinoma, GI cancer, Ovarian, Pancreatic, Prostate, Breast, Lung, Liver)
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Calcitonin
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Many Mighty Men (Metastatic Cancer, Multiple endocrine neoplasia syndrome, Medullary Thyroid Cancer)
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Human chorionic Gonadotropin (HCG)
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Two Good Gonads (Testicular, Gestational trophoblastic tumors, gonal germ cell neoplasm
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CD-117
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leimyosarcoma (uterine cancer)
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Prostatic Specific Antigen (PSA)
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prostate cancer
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Neuron Specific Enolase (NSE)
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NSM = -neuroblastoma - small cell cancer of the lung - medullary thyroid cancter (MTC)
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Serum CEA
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colorectal cancer
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CA-125
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ovarian cancer - can't screen for this but you use the tumor marker for monitoring and recurrence
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Serum Ca-15-3; CA 27.29
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breast cancer marker for monitoring and recurrence
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Testicular cancer
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hCG and AFP can give a prognosis, moniter, and recurrence
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Hepatocellular carcinoma
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AFP
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Beta 2 microglobulin
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multiple myeloma
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LDH
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non-hodgkin's lymphoma
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Staging of tumors
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TNM - tumor, nodes, metastasis (spreading)
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T = tumor size
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Tx = tumor can't be measured T0= no evidence of primary tumor (can't be found) Tis = tumor in situ T1, T2, T3, T4 = increasing size of tumor the larger the number is.
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N = nodal involvment
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NX = lymph nodes nearby cannot be evaluated N0 = no nearby lymph nodes contain cancer N1, N2, N3 = the higher the N number, the more involved lymph nodes there are.
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M = metastasis
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Mx = metastasis can't be evalulated M0 = no distant metastasis were found M1 = distant metastasis were found
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Stages of cancer
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Stage 0 = carcinoma in situ Stage 1= cancer involves primary site but has not spread to nearby tissues Stage 2 = cancer has spread to nearby areas but is still inside the primary site Stage 3 = cancer has spread throughout the nearby area Stage 4 = cancer has spread to other parts of the body Recurrent = cancer has come back after it has been treated
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MOPP
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mustard, oncovin (vincristine), prednisone, procarbazine - I like to MOPP with mustard
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ABVD
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adriamycin (doxorubicin), bleomycin, vinblastine, dacarbazine
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CHOP
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cyclophoshosphamide, doxorubicin, vincristine, prednisone
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CMF
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cyclophosphamide, methotrexate, 5-FU
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CAF
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cyclophosphamaide, adriamycin, 5-FU
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M-VAC
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methotrexate, vinblastine, Adriamycin, cisplatin
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PVB
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Platinum (cisplatin), vinblastine, bleomycin
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VAD
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vincristine, Adriamycin (doxorubicin) dexamethasone
