USMLE Step 2 CK: Next Step in Management – Flashcards

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high-grade reflux in females that persists into adulthood with no clear secondary cause
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surgical repair
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multiple 2nd trimester spontaneous abortions
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cervical cerclage
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erythematous knee with effusion and fever
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arthrocentesis [ need to tell apart gout from septic arthritis]
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spontaneous pneumothorax in a tall young man
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supplemental oxygen
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clue cells seen in vaginal swab in a fertile woman
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oral metronidazole
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acute open-angle glaucoma
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1)beta-2-antagonist eye drops i.e. timolol, betaxolol 2) carbonic anhydrase inhibitors 3) if medication fails, then a trabeculoplasty or trabeculectomy can improve aqueous drainage
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chronic sinusitis refractory to medical Tx or neurological deficits
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CT scan of the face (coronal section)
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someone with tinnitus, progressive hearing loss, and multiple episodes of vertigo
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dietary restrictions- particularly of caffeine, salt, and tobacco (Meniere's disease)
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someone that comes in with headaches and shows papilledema in the opthalmic exam
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CT scan of the head non-contrast - r/o mass
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treament for scabies
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permethrin
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Scaphoid fracture that is negative on X-ray
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spica cast and re-evaluate in 2~3 weeks
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3-hour old infant with poor feeding who vomits green material and has a double-bubble on KUB
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decompression of the GI tract...requires nasogastric tube
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mini-mental status exam of <24
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neuropsychologic testing to rule-out alzheimer's (other causes of dementia)
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cord compression confirmed with CT-spine
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dexamethasone ( before MRI of the spine to gold-standard confirm cord compression)
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Pulmonary edema in acute CHF exacerbation
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100% O2 therapy
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Pulmonary edema in acute CHF exacerbation after 100% O2 therapy
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IV furosemide
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supraventricular tachycardia with HR=160 bpm with p-wave preceding all QRS sinus rhythm
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Vagal manuevers first -carotid massage, then valsalva , then pharmacological-CCBs or adenosine
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Asymptomatic aortic stenosis
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Hydrocholorothiazide to reduce preload
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Hypertension with underlying diabetes type 2
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ACE-inhibitor or ARB
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Syncope with normal vitals and no previous episodes
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Check the electrolytes and medications - thiazide diuretics can cause hypokalemia and arrythmia
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PR interval=o.3 sinus rhythm normal
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Nothing, no management needed; PR>0.2 is first degree heartblock
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A-fib secondary to hypertension for >48 hours
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Diltiazem; rate control + anticoagulant
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A patient presents with hypertension and chest pain on exertion
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IV nitroglycerin for lowering the blood pressure
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Palpitations with underlying lung disease i.e. COPD
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72 hr Holter monitor
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Angina symptoms
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Beta-blockers - they increase the threshold of angina
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Posterior anterolateral MI and Percutaneous coronary intervention
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Clopidogrel
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teenage patient grunting and blinking many times a day for at least 1 year
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haloperidol
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prinzmetal angina
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calcium channel blockers or nitrates (also for esophageal spasm)
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Lambert Eaton Syndrome
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radiation and chemotherapy as it is the manifestation of a pre-existing small cell carcinoma of the lung.
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stroke outside the 3 hour period but within 6 hours
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intra-arterial tPA administration
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osteopenia in an elderly patient
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calcium, vitamin D, and weight-baring exercise
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tracheobronchial rupture
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bronchoscopy (flexible or rigid)
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abdominal pain out of proportion to clinical findings
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laparatomy
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Guillane Barre Syndrome
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plasmapheresis or IVIG with admission to ICU
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shoulder dystocia on observing the Turtle sign(retraction of head back into perineum)
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McRoberts maneuver - flexion of mother's thighs against her abdomen
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central retinal artery occlusion
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ocular massage with high flow oxygen
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nephrogenic diabetes insipidus
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free water and hydrochlorothiazide
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carbon monoxide poisoned pregnant lady with carboxyhemoglobin >15%
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hyperbaric oxygen (oxygen >100%)
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flu-like illness with cherry red lips; multiple family membersl; carboxyhemoglobin <25%
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100% oxygen
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a digoxin user with a potassium of 5.5 mg/dL
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Digibind (Fab fragment
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Wernicke's Encephalopathy
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thiamine, then glucose ( in that order)
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Alcohol withdrawal
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fluid resuscitation, thiamine, dextrose, folate, benzodiazepines(diazepam, chlordiazepoxide)
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septic arthritis
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ceftriaxone + vancomycin
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prophylaxis against acute limb ischemia in a person with a-fib
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dabigatran
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acute febrile non-hemolytic transfusion reaction
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discontinue transfusion, give IV acetaminophen
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acute cholecystitis
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IV fluids, pain medication, and cholecystectomy within 72 hours
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abscess size >3cm
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CT-guided percutaneous drainage
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single 2cm nodule on Chest X-ray in a 25 yo male
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check old Chest-X-ray to compare size or presence of the nodule.
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ulcer that is not infected and does not involve the bone
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debridement
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how to diagnose hepatorenal syndrome
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IV colloid challenge , if no improvement then positive for hepatorenal syndrome
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Primary light chain amyloidosis
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mephalan and prednisone
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local baldness
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minoxidil
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severe acute pancreatitis >30% necrosis on MRI
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imipenem followed by percutaneous needle biopsy
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pseudocyst on CT-abdomen
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if expanding or pain symptoms, then drain it. otherwise leave it alone.
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elderly patient with intermediate to high risk factors for coronary artery disease
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stress test
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needle-stick and unvaccinated for HepB
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give HepB IV-IgG and HepB vaccine
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MRI contraindicated in suspicious looking equivocal X-ray
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Technetium bone scan
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man comes in with a painless chancre on the penis
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swab the exudate and perform dark-field microscopy
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vesicles on skin and mucous membranes which erode into ulcers with inguinal lymphadenopathy Tzanck positive
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acyclovir famciclovir valacyclovir
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methods of treating genital warts
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cryotherapy , lasers, trichloroacetic acid or podophyllin imiquimod(originally for basal cell , acktinic akeratosis) , no side effects
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acute viral pericarditis recurrence prevention
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colchicine
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pericardial effusion
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pericardial window placement or pericardiocentesis
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pneumonia, dyspnea, dry cough fever chest pain in HIV patient
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Bronchoscopy with alveolar lavage
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dysuria, suprapubic pain, and hematuria continue despite empiric antibiotics for UTI
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CT-scan of the abdomen and pelvis
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the first test to determine beta-thalassemia anemia in genetic counseling
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complete blood count in the female (if no abnormality found, then there is no need for hemoglobin electrophoresis testing; if abnormal then test the partner)
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no menarche in a 15 year old with no medical problems and Tanner stage 1 with a uterus
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measure serum FSH (do not measure estrogen because the lack of breast development already tells you there is a lack of it)
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dog bite with suspicion of rabies
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quarantine the dog for 10 days; if asymptomatic the whole time, then no need for management (post-exposure prophylaxis)
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pinpoint calcifications in a newborn whose mother owns a cat
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pyramethamine and sulfadiazine (Treats toxoplasmosis)
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peripartum cardiomyopathy - biventricular cardiac failure
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supportive care
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eisenmenger's syndrome in a pregnant woman
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avoid hypotension give pressors
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Rheumatic mitral stenosis in a pregnant woman
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decrease the heart rate to allow time for blood to fill the left ventricle; reduce the IV fluid volume
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pregnant woman of 16 weeks gestation with fasting blood glucose of 140 mg/dL
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do quadruple marker screen assess for neural tube defects - specifically caudal regression syndrome - she has overt diabetes mellitus.
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Estimated fetal weight is >4.5kg by sonogram
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C-section
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perinatal management of gestational diabetes
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IV D5w with insulin drip maintain glucose within 80-100mg/dL
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non-reactive stress test
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vibroacoustic stimulation- wake up the baby because most commonly non-reactive ST due to the baby sleeping
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non-reactive stress test with positive contraction stress test
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delivery the baby immediately
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fibromuscular dysplasia
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percutaneous angioplasty with stent placement
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4 month old boy with leg-length discrepancy and positive Ortolani test
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U/S of the hip followed by Pavlik Harness (splint that holds hip in flexion and abduction) - prevents extension and adduction
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45 yr old woman overdosed on pills comes in with tinnitus, fever, and tachypnea
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aspirin intoxiciation - supportive care, activated charcoal, IV hydration, bowel irrigation moderate intoxication =>IV sodium bicarbonate to alkalinize the urine and promote excretion severe intoxication => hemodialysis
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suspicion in an immigrant man with hypopigmented skin patch with loss of sensation. Had a flu-like illness 1 month prior.
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perform a skin biopsy -> top ddx is Lepromatous leprosy.
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A man with mediastinal widening on chest X-ray and equal blood pressures on both arms and moderate pericardial effusion
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Trams esophageal echo
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5 day old newborn has lost 7% of their body weight
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follow up 10-14 days to see if baby has regained it (normal loss of fluid due to labor and in-utero)
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skin lesions in a patient with celiac disease
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dapsone (Tx for dermatitis herpetiformis)
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clinical suspicion for abnormal uterine bleeding
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endometrial biopsy
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reproductive-age woman with widespread pain ,fatigue, poor-sleep, frequent headaches and tenderness to palpation of her neck, shoulders and back. Vitals and labs are normal.
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exercise program with aerobic conditioning (Tx for fibromyalgia). Medications - duloxetine, TCAs are a secondary measure.
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1 month old boy with a harsh holosystolic murmur over the left lower sternal border
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echocardiography - he has a VSD
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infant with symmetric descending paralysis, drooling and constipation, poor suck and gag reflex also seen
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botulism immuneglobulin + supportive therapy(respiratory support, NGT feeding)
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Lichen sclerosus
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corticosteroids
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admission to inpatient ward with febrile neutropenia
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piperacillin-tazobactam
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cafe au lait spots with sensorineural hearing loss
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MRI with gadolinium (suspect acoustic neuroma)
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MI status post CABG post-op day 5 small pericardial effusion with fever, tachycardia, a-fib.
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drainage, surgical debridement and antibiotics ( acute mediastinitis)
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DVT identified on ultrasound
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CT scan of abdomen, chest, and pelvis - search for any embolism
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Rhabdomyolysis
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IV fluids, mannitol and bicarbonate
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Baseline EKG changes on patient with SSx of stable angina
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Stress echocardiography instead of exercise treadmill stress test -- (echo you need to have a normal EKG reading at rest)
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presence of bilateral popliteal artery aneurysms
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CT Abdomen -> 25% chance of abdominal aortic aneurysm present.
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Asystole
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CPR and epinephrine(lowers defibrillation threshold, increases myocardial and cerebral blood flow) ; defibrillation does not work for asystole
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hepatorenal syndrome
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midodrine and octreotide
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Needlestick from an HIV infected person
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Triple HAART therapy for 28 days
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pancreatic cancer with elevated direct bilirubin
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endoscopic stent to relieve jaundice from extrahepatic cholestasis
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positive whiff test
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amine production with KOH prep = bacterial vaginosis -- Tx --> clindamycin or metronidazole
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symptoms of malabsorption returning from a foreign country
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Tx empirically with metronidazole. i.e. giardiasis, amoebiasis.
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skin rash in a person with gluten-intolerance
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dapsone for dermatitis herpetiformis
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patient with hypothermia at 32-35C, 28-32C, and 27C degrees
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general - IV hot crystalloid for hypotension with endotracheal intubation in comatose patients. 32-35 degrees - dry and cover with blankets 28-32 degrees - warm bath, heating pad, blankets <28 degrees - pleural, peritonealwarm irrigation -internal rewarming
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recurrent coughs with mucopurulent sputum
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CT scan - bronchiectasis - dialated bronchiolar airways
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microcytic, hypochromic anemia in an otherwise healthy adult
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test for stool occult blood - because the most common cause of iron-deficiency anemia is GI blood loss. Otherwise, colonoscopy is indicated because it has a higher sensitivity and specificity
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meningitis in people age 2-50
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vancoymcin + 3rd generation cephalosporin
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meningitis in people older than 50
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vancomycin + ampicillin + 3rd generation cephalosporin
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infection post-neurosurgery shunt
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vancomycin + 4th generation cephalosporin (cefepime)
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meningitis in an immunocompromised state
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vancomycin + ampicillin + 4th generation cephalosporin(cefepime)
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infection after penetrating trauma to the skull
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vancomycin + 4th generation cephalosporin (cefepime)
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Tx of carcinoid syndrome
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octreotide for symptomatic patients before surgery
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patient has blood cultures that grow Streptococcus bovis and has vegetations on mitral valve
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perform colonoscopy NOT FOBT- colonoscopy is more sensitive and specific
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patient had a Hx of flu ten days earlier but now has increased tactile fremitus in LLL of the lung and a fever
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Tx: anti-staph penicillin i.e. methicillin, oxacillin, dicloxacillin, naficillin - most common organism is Staph aurues post-influenza pneumonia.
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patient with a PMH of drug addiction and addiction comes in with severe pain from a motor vehicle accident. What analgesic do you give him?
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Give him IV morphine. It doesn't matter what his drug abuse history is. Physicians never undertreat pain even with a risk of abuse.
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lupus nephritis
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1. mycophenolate mofetil 2. cyclophosphamide + corticosteroids OR 3. azathioprine + corticosteroids
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MALT lymphoma restricted to the mucosa with no lymph node involvement
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PPI + clarithromycin + amoxicillin ( most common cause is H-pylori) then use
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multiple consecutive PVCs without symptoms what if you DO have symptoms with multiple consecutive PVCs?
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observation; if multiple consecutive PVCs with symptoms then you give beta-blockers first, then amiodarone as a second-line therapy.
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cancer-related anorexia and/or cachexia symptoms
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megestrol acetate ( progesterone analogs) they are superior to cannabinoids
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positive PPD test in HIV patients
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isoniazid + vitamin B6 for 9 months.
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unstable patient with narrow-complex tachycardia
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DC cardioversion stat supraventricular tachycardia = narrow complex tachycardia
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patient with flank pain gets abdominal imaging showing 6mm calculus in distal right ureter. No hydronephrosis seen. IV hydration and analgesics started. What is the next step?
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alpha-1 receptor blocker i.e. tamsulosin - acts at the distal ureter lowering muscle tone and reduces ureteral spasm from stone impaction.
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elderly patient with abnormal gait, incontinence and dementia showing enlarged lateral ventricles on CT scan
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1. serial large volume lumbar punctures 2. ventriculoperitoneal shunting if symptoms relieved by sequential CSF removal by the lumbar punctures
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painless hematuria with elevated hemoglobin, 50 pk-yr smoking history
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CT Scan of the Abdomen
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symmetrical pain and stiffness in the neck, shoulders, and hip with elevated ESR
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low dose prednisone ( Polymyalgia Rheumatica)
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widened pulse pressure, irregular breathing, and elevated ICP
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intubation with possible ventilation, elevated head of the bed , mannitol
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symmetric descending flaccid paralysis that started with dry mouth and diplopia
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administer antitoxin with high clinical suspicion simultaneously with collecting specimens identify in stool, serum or gastric lavage -> botulinum toxin.
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hypertonic extremities with lockjaw
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(1)admit to ICU immediately, (2) diazepam, and give (3)1x dose of IM tetanus immunoglobulin (4) active immunization with Td(tetanus/diptheria toxoid)
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empiric osteomyelitis Tx
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cephalosoprins, fluoroquinolones, vancomycin, linezolid, daptomycin, and clindamycin rifampin for biofilm penetration If gram negative suspected add aminoglycoside +/- beta lactam
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septic arthritis in an immunocompetent adult
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IV beta lactamase resistant penicillin --> oxacillin OR 1st generation cephalosporin ; MRSA coverage -> vancomycin
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septic arthritis in a immunocompromised adult
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broad spectrum antibiotic - 3rd generation cephalosporin OR aminoglycoside ; consider pseudomonal coverage with aminoglycoside + extended spectrum pencillin
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warts
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(1) freezing lesions with liquid nitrogen (2) salicylic acid daily topically applied for several weeks (3) 5-FU cream - retinoic acid cream for flat warts (4) surgical excision OR laser therapy (5) podophyllin for genital warts
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molluscum contagiosum
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(1) curettage (2) podophyllin drops (3) cantharidin (4) cryosurgery
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silvery scales on knees and elbows
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corticosteroids are first line calcipotriene and calcitriol - 1st/ 2nd line tars tazarotene ( vit A derivative) anthralin (anthracene derivative - smoke carcinogen)
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young woman with tender breast mass on the upper outer quadrant. LMP was three weeks ago. She has no family history of breast cancer.
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Ask her to come back after the menstrual period and ask her to take note if the size of the mass has decreased after the menstrual period. Otherwise ultrasound, FNA, and excision biopsy would be the option.
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acute exacerbation of COPD
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IV methylprednisolone 1-2x doses followed by oral therapy for 5 days.
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allergic conjunctivitis
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olopatadine, azelastine
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non-herpes viral conjunctivitis
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supportive therapy, warm compresses
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collapsed gestational sac with no fetal heart tone on transvaginal ultrasound in a hemodynamically stable female at 8 wks gestation
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follow-up outpatient ; no suction and curretage.
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meningitis in a 55 year-old man
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3rd gen. cephalosporin + vancomycin + ampicillin + dexamethasone
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bruit left periumbilical region on auscultation in middle-aged man with hypertension
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captopril renal scan
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eye pain with Hx of occupational trauma
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tetracaine for pre-op anesthesia prior to Fluorescein slit lamp examination
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elderly male comes in with 1 episode of syncope with no smoking history BP equal on both arms and widened mediastinum and pericardial effusion on chest X-ray
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transesophageal echocardiogram --> it could be a type A retrograde aortic dissection , so the BP could be normal.
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frostbite injuries
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rapid rewarming with warm water
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high blood pressure in an otherwise healthy woman of child-bearing age
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1st step: discontinue oral contraceptive pills 2nd step: diet and exercise 3rd step: introduce thiazide diuretic
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5mm radiolucent stone in the ureter
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potassium citrate --> uric acid is soluble at high pH
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elderly male with history of recurrent aspiration presents with neck mass and RLL consolidation
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barium esophagram to rule out Zenker's diverticulum, CT scan of neck is indicated for airway obstruction by foreign object; bronchoscopy is 2nd line.
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postpartum fever with leukocytosis and non-foul smelling bloody vaginal discharge
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reassurance. You don't even need empirical antibiotics. Endometritis requires the presence of foul smelling lochia
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acute exacerbation of COPD
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non-invasive positive end expiratory pressure for 2hours
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acute exacerbation of COPD with failed NPPV trial
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mechanical intubation
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malignant hypertension
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lower BP 10-20% in the first hour , then 5-15% across the next 23 hours.
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hypertension diagnosed in a young individual
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suspicion for co-arctation of the aorta --> check for radio-femoral delay..associated with Turner's, bicuspid aorta, and VSD.
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adnexal mass in a postmenopausal woman.
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transvaginal ultrasound AND CA-125 serum marker
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progressive back pain in prostate cancer patient with previous orchiectomy
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radiation therapy (the answer is NOT flutamide or any medical management)
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white cloudy dialysate with tender abdomen in a patient getting peritoneal dialysis.
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trial of antibiotics cefazolin and ceftazidime; if refractory, then remove the catheter.
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positive Tinel's sign and flick test
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First line: wrist splint 2nd line: injected glucocorticoids 3rd line: surgery
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fever, hypertension and tachycardia along with altered mental status
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give Librium ( chlordiazepoxide) the patient is going through EtOH withdrawal
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post-ictal metabolic acidosis on admission
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wait 60-90 min. for the metabolic acidosis to resolve, then redraw labs. No need for immediate medical intervention.
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Failure of MALToma to regress after eradication of H-pylori with triple therapy
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CHOP therapy - cyclophosphamide, adriamycin, vincristine, and prednisone +/-bleomycin
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woman in her thirties whom results for for AchR antibodies test came back positive
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CT scan of the anterior mediastinum -- a thymoma is more specific than a Tensilon(Edrophonium) test
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opening snap with diastolic rumble in a patient who had a respiratory illness with joint pain an swelling recently
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IM benzathine penicillin G once a month for 5 years or until 21 years old (whichever is longer) for rheumatic fever + carditis rheumatic fever + carditis but no proven heart or valve disease (echocardiogram/clinical) - 10 years or until 21 yrs old - whichever one is longer rheumatic fever + carditis, heart or valve disease = 10 yrs or until 40 years old
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precocious puberty showing elevated LH at baseline
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MRI of the brain - need to rule out central vs. peripheral gonadotropin dependent precocious puberty
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cat bite with puncture wound showing no debris or active bleeding in a patient with recent Td vaccination <5 yrs
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amoxcillin-clavulanate for Pasteurella multocida
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dyspnea and tachycardia in a pregnant woman with low pretest probability of P.E. chest X-ray
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d-dimer in a pregnant patient has high false negative rate; need to perform V/Q scan to rule out P.E. If V/Q is equivocal then perform CT angiogram.
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urge incontinence
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bladder training ; 2nd line is oxybutynin(anticholinergic) and mirabegron(beta-3 adrenergic agonist @ the detrusor)
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gas gangrene infection
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IV penicillin - 24 million units per day
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1 or 2 coronary vessel stenosis
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angioplasty and stent followed by Gp2b3a inhibitor i.e. tirofiban or abiciximab
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postmenopausal woman with pruritis of the vulvar region that is refractory to medical management
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vulvar biopsy.
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history of cancer with suspicion of bony metastasis i.e. back pain
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radionuclide bone scan ( X-ray of the back is to rule out other causes of bone pain because radionuclide bone scan has high sensitivity BUT low specificity)
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suspicion for SLE; which lab test first
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anti-nuclear antibody first because of high sensitivity; use anti-dsDNA antibody as a confirmation test because of high specificity
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amytrophic lateral sclerosis
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riluzole - glutamate receptor antagonist
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moderate-to-severe restless leg syndrome
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1st line - pramipexole, ropinirole 2nd line - alpha-2-delta calcium channel agonists i.e. gabapentin enacarbil
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mild restless leg syndrome
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1) iron supplementation if serum ferritin <75 2) supportive measures - heating pad exercise 3) avoid triggers - sleep deprivation, medications
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sore throat two weeks after starting PTU for treatment of Graves disease
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stop PTU. It is causing the agranulocytosis
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person with a core body temperature of 88 degrees F, bradycardia and hypotension
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active rewarming with blankets - hypothermia will slow the heart and the blood vessel vascular resistance.
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patient brought to E.R. after smoke inhalation from a burning building
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100% oxygen by facemask - first suspicion is carbon monoxide poisoning.
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recent gastrectomy with nausea, diarrhea, abdominal pain and palpitations
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manage diet -- dumping syndrome - small frequent meals, avoiding simple sugars, increase fiber and protein, drink fluids during rather than after meals.
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patient with Hx of tonic-clonic seizures comes in post-seizure 15 min. ago and has a pH of 7.2. confused and appears confused. anion gap is elevated.
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This patient has post-ictal lactic acidosis. No management for the first two hours and draw second labs. a pH >7.1 does not require intervention. If value <7.1 then IV sodium bicarbonate is indicated.
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unilateral renal artery stenosis 80%
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treat initially with ACE-I or ARBs. stenting and surgical revascularization is reserved for patients with resistant HTN or flash pulmonary edema or refractory heart failure due to severe HTN
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patient shows morning glucose of 300mg/dL consistently; they deny any late night snacks
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make them record their blood sugar at 3am - to determine Somogyi (rebound hyperglycemia 2/2 hypoglycemia) or Dawn effect (cortisol and growth hormone effects)
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PCP intoxication
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benzodiazepines - midazolam, diazepam, or lorazepam ; 2nd line is haloperidol
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R supraclavicular lymph node biopsy shows squamous cell carcinoma cells
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do a panendoscopy because the cancer is coming from larynx, bronchus or esophagus most likely.
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nausea and vomiting caused by chemotherapy
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ondansetron + Fosaprepitant + dexamethasone ( 5HT3 antagonist and NK-1 antagonist) dexamethasone mechanism unclear.
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condyloma acuminata - patient wants self-treatment
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imiquimod (induction of IFN-alpha leading to reduction in HPV viral DNA synthesis). Canthardin and Podophyllin require in-office administering of the drug.
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vomiting, lethargy, dehydration, with posturing in a 10 month old infant
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IV dexamethasone; increased ICP can counteract vasogenic edema - corticosteroids have an anti-inflammatory and membrane stabilizing effect
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pediatric patient 4 years old has PPD <5mm but lives in the same house as someone who has
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isoniazid _ vit B6 along with follow up PPD test in 8-12 week- the kid is still exposed to T.B.
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agitation and chest pain in someone with acute-onset chest pain who recently used cocaine
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benzodiazepine --> use diazepam
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patient comes in with tearing chest pain radiating to the back, has a moderate pericardial effusion and happens to be hemodynamically stable
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CT angiogram - definitive test for aortic dissection
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an unchanged consolidation in the right lower lobe of the lung after multiple bouts of pneumonia
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CT scan of the chest -- concern for malignancy. Bronchoscopy is most commonly for biopsy of hilar centrally located masses.
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adnexal mass palpated in a post-menopausal woman
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need to obtain a serum CA-125 ( pelvic U/S would have been the first intervention in a pre-menopausal woman)
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temporal lesions on MRI in a male with seizure. He also has a fever and altered mental status
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empirical treatment with IV acyclovir. If IV acyclovir fails , then lumbar puncture is warranted.
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male in his 20s diagnosed with HOCM, refractory to beta blockers and calcium channel blockers
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myomectomy
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vomiting in a young child with olive-shaped mass in the epigastric region
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correct the metabolic alkalosis first, then consult for surgery for pyloromyomectomy
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