Unit 9 Ch 13 – Flashcards
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            _____________ strengthening occurs when synapses are active while the membrane of the postsynaptic cell is depolarized.
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        Synaptic
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            Classical conditioning occurs when __________ stimuli and responses are transformed into ____________ stimuli and responses.
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        unconditional, conditional
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            _______________ receptors are glutamate receptors found in the hippocampal formation that control calcium ion channels.
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        NMDA
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            People with anterograde amnesia
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        show impairment of complex relational learning.
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            This type of learning involves learning about relationships among many stimuli.
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        Spatial learning
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            Learning to recognize music, learning sequences, and classical conditioning are examples of ____________ memory tasks.
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        nondeclarative
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            An increased number of ______ receptors in the postsynaptic membrane strengthens the synapse.
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        AMPA
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            Damage to the basal ganglia or infusion of a drug that blocks NMDA receptors there can disrupt
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        instrumental conditioning
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            A ___________ excitatory postsynaptic potential (EPSP) is an intracellular measurement of the EPSPs produced by the synapse of the perforant path axons with the dentate granule cells.
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        population
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            ______________ refers to the process by which experiences change our nervous system and hence our behavior.
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        Learning
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            The acquisition of specific behaviors and skills is the most important form of __________ memory.
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        implicit
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            __________ is/are involved in the acquisition of episodic memories and complex behaviors that involve deliberation or instruction.
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        Transcortical connections
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            The ____________ is part of an important system involved in classically conditioned emotional responses.
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        amygdala
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            An increase in the magnitude of excitatory postsynaptic potentials in postsynaptic neurons over the long term is known as
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        long-term potentiation
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            Which of the following is NOT one of the four basic forms of learning?
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        emotional learning
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            Memories can be altered or connected to newer memories through a process known as ________.
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        reconsolidation
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            In the visual cortex, the ________ stream is involved with object recognition, whereas the ________ stream is involved with perception of the location of objects.
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        ventral, dorsal
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            Which of the following was NOT a conclusion drawn by Milner with regard to pure amnesia?
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        The hippocampus is not involved in converting immediate memories into long-term memories.   DID conclude: The hippocampus is involved in converting short-term memories into long-term memories.  Incorrect answer The hippocampus is not the location of short-term memories.   The hippocampus is not the location of and is not necessary for the retrieval of long-term memories.
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            This might explain how neurons are changed by experience in a way that would cause changes in behavior.
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        Hebb rule
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            James Olds and Peter Milner reported that electrical stimulation of rat brain
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        could have reinforcing effects.
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            Functional-imaging studies have shown that specific types of short-term visual memories involve activity of specific regions of the
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        visual association cortex.
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            When a rat encounters a painful stimulus, somatosensory input activates strong synapses in the
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        lateral nucleus
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            Recognizing people by the shape of their faces and recognizing objects by how they feel or smell are examples of
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        Perceptual learning
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            Neural circuits that contain memories are established by strengthening some synapses and weakening others; the low-frequency stimulation of synaptic inputs to a cell can __________ their strength in a phenomenon known as ________________.
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        decrease, long-term depression
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            Providing a drink of water to a thirsty animal is an example of ___________ conditioning
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        instrumental
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            A woman sustains physical abuse whenever her husband drinks whiskey. When she sees a whiskey bottle on the table, her stomach churns and she becomes fearful. What is the unconditional stimulus?
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        The physical abuse  The unconditional stimulus is one that triggers an automatic, unlearned response. Physical abuse naturally stimulates fear.
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            What process may be at the root of a successful classical conditioning experiment?
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        Associative long-term potentiation  Associative LTP is the increase of a weak synapse due to association with a strong synapse. Thus, an unrelated, neutral stimulus can come to trigger a specific response.
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            What enables structural or biochemical changes at synapses?
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        Synaptic plasticity  Synaptic plasticity enables structural and biochemical changes at synapses.
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            A man develops herpes simplex encephalitis resulting in destruction of the hippocampus. Why does he experience retrograde amnesia for events within 15 years of the brain injury but not for older memories?
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        Older memories are not stored in the hippocampus; newer memories are still being consolidated.   The hippocampus converts short-term memories to long-term memories (consolidation) but long-term memories are stored in other brain regions. See below.
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            What mechanisms are involved in long-term potentiation (LTP)?
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        Opening of NMDA channels, post-synaptic depolarization, rise in post-synaptic calcium concentration  LTP involves opening of NMDA channels, post-synaptic depolarization, and increase in post-synaptic calcium concentration.
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            Why is it important for neuron stimulation to be rapid for LTP to occur?
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        Rapid stimulation depolarizes the dendritic spine of the postsynaptic neuron, allowing for strengthening of weak synapses.
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            A man hiking in the mountains is using headphones to listen to blues songs by Billie Holiday. He missteps, falls down a deep embankment, and is seriously injured. After a long and painful recovery, the man notices that whenever he hears a Billie Holiday song, he becomes anxious and panicky. What is the conditional stimulus, what neurological process does it illustrate, and in what brain structure has learning taken place?
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        The music; long-term potentiation; the amygdala
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            Eyewitness accounts of crimes have sometimes been found to vary after more is learned about an incident. What mechanism is most likely responsible for this phenomenon?
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        Reconsolidation
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            The research by Knecht in 2004 demonstrated that __________ is an essential part of long-lasting, long-term potentiation.
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        dopamine  (specifically L-DOPA)
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            The memory loss experienced by the famous case of H.M. was the result of surgery for his ______.
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        463 epilepsy speech disorder brain tumor
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            Damage to the hippocampus or to regions of the brain that supply its inputs and receive its outputs, causes ________ amnesia.
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        anterograde
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            Research has shown that memories older than approximately ____ years are relatively intact in people with __________ amnesia.
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        fifteen, retrograde
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            To successfully retain information in short term memory, two processes are required. The first is to filter out irrelevent information, involving the __________, and the second is to maintain relevant information, involving the ________.
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        basal ganglia; right prefrontal cortex
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            An action potential that occurs in some type of pyramidal cells, and plays a role in learning, is called a
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        dendritic spike
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            Which of the following is not part of the limbic cortex of the medial temporal lobe?
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        amygdala
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            Semantic dementia is caused by degeneration of the neocortex of the _______.
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        anterolateral temporal lobe
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            The Morris water maze requires which of the following types of learning?
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        relational
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            There is considerable evidence that when learned behaviors become automatic and routine, they are transferred to the ______.
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        basal ganglia
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            Learning to recognize faces, melodies, and pictures are all examples of _________.
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        non declarative memory tasks
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            ___________ memories can be acquired gradually, whereas ___________ memories must be learned all at once.
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        Semantic, episodic
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            A researcher examines the right posterior hippocampus of New York taxi drivers, and compares the size to non-taxi drivers. What do you think he will find?
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        455-456  The right posterior hippocampus of the taxi drivers will be smaller than the same area in non-taxi drivers.   The right posterior hippocampus of the taxi drivers will be about the same size as the same area in non-taxi drivers.   The right posterior hippocampus of the taxi drivers will be larger than the same area in non-taxi drivers.
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            Models such as the gill withdrawal reflex in Aplysia and the eyeblink reflex in the rabbit have been used to study
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        classical conditioning.
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            Research by Owen (1992) and Koroshetz (1993) demonstrate the importance of the basal ganglia in the learning of automatic responses. The subjects were patients with _______ and ________, both of which are degenerative diseases of the basal ganglia.
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        Parkinson's; Huntington's
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            The dorsal stream of the visual cortex continues into the ___________ and carries information relating to _______________.
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        posterior parietal cortex, object location
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            Stimulus-response learning involves the ability to
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        exhibit a specific behavior in the presence of a specific stimulus.
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            You are listening to a song on the radio while doing your homework. The phone rings. Yourmother has called to tell you that your favorite uncle has died after being hit by a car. Threemonths later, you again hear the same song and suddenly feel very sad. In this example,the unconditional response is
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        feeling sad when your mother calls with the bad news.
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            Which of the following is true of motor learning?
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        Motor learning involves changes in the motor pathways.
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            Long-term potentiation may involve the formation of ________ within the postsynapticdendrite, which then acts on the presynaptic element to increase the release of ________.
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        nitric oxide; glutamate
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            Which factor below normally prevents the calcium channel of the NMDA receptor fromopening in response to only glutamate?
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        The channel is blocked by Mg2+ ions.
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            ________ is a strong candidate to act as a retrograde messenger from the dendrite to theterminal button.
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        Nitric oxide
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            An example of a natural reinforcer is
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        food for a hungry rat.
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            Damage to the ________ would be expected to impair instrumental learning in rats.
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        basal ganglia
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            Procedural memory does not rely on the _______ and ________ memory system in the same way as ________ memory.
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        hippocampus; medial temporal lobe; declarative
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            Which is true of anterograde amnesia?
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        They may not recognize people they met just moment's before, and  It results from a failure of memory encoding and storage.
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            H.M. could learn parts of new motor skills.
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        True; Patient H.M. was able to perform all of the following tasks quite well except consolidating
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            The ________ plays a key role in short-term memory for all sensory systems.
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        prefrontal cortex
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            Transcranial magnetic stimulation (TMS) can disrupt neural circuits in awake humans. Thenotion that short-term memory (STM) for a visual stimulus involves continued activation ofthe appropriate visual association cortex is supported by studies in which
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        TMS applied to the ventral stream disrupted STM for a visual pattern.
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            CER is blocked by AP5 (_______) in the __________.
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        NMDA antagonist; amygdala
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            A stimulus that predicts an ______ outcome will change neural transmission in the ______ to produce the somatic, autonomic and endocrine signs of _______, as well as increased attention to that stimulus.
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        aversive; amydala; fear
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            One of Toms friends has a night of boozing on many Vodka screwdrivers, and eating much pizza and salad with bacon bits. After becoming sick, she refuses to eat bacon bits. This is an example of which type of memory?
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        classical conditioning.
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            Declarative memory is synonymous for __________.
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        explicit memory
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            Memory for skills and habits are not formed in the hippocampus.
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        True; Hippocampal damage produced by anoxia releases glutamate, which in turn activates NMDA
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            Which of the following is not a unique feature of episodic memory?
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        Storage of information is highly sensitive to context.  ARE KEY FEATURES:  Episodic memory, unlike semantic memory, is self-centered. Episodic remembering takes the form of mentally "traveling" in subjectively experienced time.  Brain damage is more likely to impair episodic remembering than semantic knowing. The key function of episodic memory is to allow the individual to remember personal past happenings as such; semantic memory is not capable of this function.
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            The right hippocampal formation is activated by
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        spatial information
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            Which of the following is not a common feature of semantic and episodic memory?
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        Behavioral expression of what is retrieved is obligatory.    ARE COMMON FEATURES:   Both systems allow the organism to know about aspects of its world that are not immediately present.  Storage of information is highly structured. The shared features of both systems are present in a wide range of animals. The operations of neither system depend on language.
