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Home Page Flashcards sodium valproate C8H15NaO2 structure - Flashcards

sodium valproate C8H15NaO2 structure – Flashcards

Flashcard maker : Julie Noel
C8H15NaO2 structure
Molecular Formula C8H15NaO2
Average mass 166.193 Da
Density
Boiling Point
Flash Point
Molar Refractivity
Polarizability
Surface Tension
Molar Volume
  • Experimental data
  • Predicted – ACD/Labs
  • Predicted – ChemAxon
  • Experimental Physico-chemical Properties

    • Experimental Melting Point:

      300 °C LKT Labs
      [V0147]
      320 °C LabNetwork LN00202004

    • Experimental Solubility:

      Soluble to 100 mM in water Tocris Bioscience 2815
      Soluble to 100 mM in water and to 50 mM in DMSO Tocris Bioscience 2815
  • Miscellaneous

    • Safety:

      22-61-36/38-36/37/38 LKT Labs
      [V0147]
      H302 LKT Labs
      [V0147]
      IRRITANT Matrix Scientific 099961
      Xn, T, Xi, Repr. LKT Labs
      [V0147]

    • Target Organs:

      GABAR;HDAC inhibitor TargetMol T1602

    • Compound Source:

      synthetic Microsource
      [01500606]

    • Bio Activity:

      Chromatin/Epigenetic;Neuroscience TargetMol T1602
      Deacetylases Tocris Bioscience 2815
      Enzymes Tocris Bioscience 2815
      GABAR;HDAC2, HDAC9 TargetMol T1602
      Histone deacetylase inhibitor Tocris Bioscience 2815
      Histone deacetylase inhibitor (IC50 = 400 ?M) that exhibits anticancer, anti-inflammatory and neuroprotective effects. Displays anticonvulsive activity via an increase in GABA levels and decreases A?
      production in animal models of Alzheimer’s disease. Also attenuates NMDA-mediated excitation, blocks voltage-gated Na+ channels and modulates firing of neurons. Enables induction of pluripotent stem c
      ells from somatic cells by Oct4 and Sox2. Can induce autophagy by inhibiting inositol synthesis. Tocris Bioscience 2815
      Histone deacetylase inhibitor (IC50 = 400 ?M) that exhibits anticancer, anti-inflammatory and neuroprotective effects. Displays anticonvulsive activity via an increase in GABA levels and decreases A? production in animal models of Alzheimer’s disease. Also attenuates NMDA-mediated excitation, blocks voltage-gated Na+ channels and modulates firing of neurons. Enables induction of pluripotent stem cells from somatic cells by Oct4 and Sox2. Can induce autophagy by inhibiting inositol synthesis. Tocris Bioscience 2815
      Histone Deacetylases Tocris Bioscience 2815

Predicted data is generated using the ACD/Labs Percepta Platform – PhysChem Module

No predicted properties have been calculated for this compound.

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