PHLT 305 Exam 1, Epidemology Midterm – Flashcards
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Epidemic
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the occurrence in a community or region of cases of an illness, specific health-related behavior, or other health-related events clearly in excess of normal expectancy
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Pandemic
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an epidemic occurring worldwide
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Epidemiology
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the distribution and determinants of health and diseases, morbidity, injuries, disability, and mortality in populations
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Population
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all the inhabitants of a given country or area considered together
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Distribution
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the occurrence of diseases and other health outcomes varies in a population with some subgroups of the populations more frequently affected than others
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Determinant
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any factor that brings about change in a health condition or other defined characteristic
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Exposure
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contact with a disease-causing agents or to the amount of factor that impinges upon a group or individuals
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Outcome
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all of the possible results that may stem from exposure to a causal factor
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Morbidity
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illnesses due to a specific disease or health condition
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Mortality
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causes of death
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Quantification
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counting of cases of illness or other health outcomes
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Epidemiology is a _______ science
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interdisciplinary
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Analytical epidemiology
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examines causal hypotheses regarding the association between exposures and health conditions
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Descriptive epidemiology
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characterizes the amount and distribution of health and disease within a population
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Natural experiments
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naturally occurring circumstances in which subsets of the population have different levels of exposure to a hypothesized causal factor in a situation resembling an actual experiments
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Hippocrates
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Classical Antiquity Wrote on Airs, Waters, and Places which suggested disease might be associated with environmental factors
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Black Death
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Middle Ages killed 1/3 of Europe transmitted by Yersinia pestis
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Paracelsus
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Renaissance founder of toxicology discovered dose-response relationship
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John Graunt
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Renaissance Columbus of statistics
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Ramazzini
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Eighteenth Century founder of occupational medicine
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Sir Percival Pott
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Eighteenth Century first person to decribe an environmoental cause of cancer
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Edward Jenner
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Eighteenth Century developed a vaccine for smallpox
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William Farr
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Nineteenth Century Developed coding for medical conditions Linked mortality and population density
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Robert Koch
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Nineteenth Century Koch's postulates demonstrated the association between a microorganism and a disease
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Koch's Postulates
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1. the organism must be observes in every case of the disease 2. It must be isolates and grown in a pure culture 3. The pure culture must, when inoculated into a susceptible animal, reproduce the disease 4. The organism must be observed in, and recovered from, the experimental animal
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1918 Spanish Flu
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Killed 50 to 100 million 1/3 of the population was infected
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Alexander Fleming
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Discovered the antimicrobial properties mold Penicillium notatum to make Penicillin
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Operations Research
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Defined as a type of study of the placement of health services in a community and the optimum utilization of services
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Disease Management
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Refers to a method of reducing healthcare costs by providing integrated care for chronic conditions
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Reference population
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cases of a disease have been lost ex: crude death rate in the US
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Case Fertility Rate
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# deaths due to a disease that occur among people who are affected by it #deaths/ #cases
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Ethics
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promotes aims of research collaborative efforts accountability public support moral and social values
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IRB
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internal review board oversees and approves studies for ethical research
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Descriptive Epidemiology
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Who was affected, where it occured, and when did it occur Types (case reports, case series, and cross sectional studies)
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Case study
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simgle occurence of a noteworthy health related incident ex: adverse reactions due to cosmetic surgery in the US
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Case series
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Multiple cases linked by disease ex: reported cases of primary meningoephalitis (121 reported between 1937 and 2007)
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Cross-sectional
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relationship between diseases in a population AT ONE TIME ex: behavioral risk factor surveillance system (BRFSS)
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Nativity
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place of origin
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Socioeconomic Status
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Person's position in society (income level, education level, job)
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Secular trends
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gradual changes in frequency of disease over long time periods Ex: heart disease has increased
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Cyclic Trend
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increases and decreases in frequency of a disease over a period of several years ex: weather events in atlantic basin mortality for flu peaks in feb
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Cluster
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closely grouped series of events or cases of a disease in relation to time or place
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Spatial clustering
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aggregation of events in a geographic region
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Temporal clustering
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occurence of events related to time
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Surveillance
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continous systematic data collection of health-related data leads to informed action
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how do you know if surveillance is working
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external validity, data quality, sensitivity, flexibility, timeliness
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Hippocrates
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broke disease superstition
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bubonic plague
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caused by tersina pestis (fleas)
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Paracelsus
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alchemist
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John Graunt
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quantitative methods
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Bernardini Ramazzini
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occupational medicine
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Sir Percival Pott
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Environmental cancer
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Edward jenner
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father of vaccination
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john snow
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first to say diseases can spread through water
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Robert Koch
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microorganisms and disease
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Kochs postulates
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must be present in every case must be isolated be able to transmit disease recover from animal to which disease was transmitted
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observational science
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naturally occurring situations
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Contact with a disease-causing factor or the amount of the factor that affects a group of individuals is referred to as exposure.
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True
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The occurrence in a community or region of cases of an illness, specific health behavior, or other health related events clearly in excess of normal expectancy is known as a(n
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Epidemic
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Illness due to a specific disease or health condition is known as
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Morbidity
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Bubonic plague is a bacterial disease caused by Vibrio Cholorae
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false
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The most important public measure to protect health is vaccination
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False
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Pandemic
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outbreak occurring worldwide or crossing international boundaries
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The physician who determined that a human disease was caused by a specific living organism and proceeded to develop four postulates to demonstrate the association between a microorganism and a disease was
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Robert Koch
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John Snow
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The English anesthesiologist who linked cholera outbreaks to contaminated water and innovated several of the key epi measures was
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Hippocrates
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Ancient Greek who contributed to epidemiology by departing from superstitious reasons for disease outbreak was
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Data cleaning
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review for accuracy and completeness
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incidence
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occurence of new disease within a defined period of time #new cases/# individuals in population at risk
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point prevalence
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# existing cases / total number in group
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count
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number of cases of a disease
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Causes prevalence to decrease
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Decirease in incidence Shorter duration of a disease In-migration of healthy people Improved cure rate
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causes prevalence to increase
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Increase in incidence Longer duration of case In-migration of cases Prolongation of life without a cure
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Members of the population who are capable of developing a disease or condition
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population risk
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counting and tabulating cases
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One of the first steps in presenting data after they have been reviewed for accuracy and completeness
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Lifetime prevalence
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all cases of a disease diagnosed at any time during a persons lifetime
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when incidence rate of a disease increases
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prevalence increases
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rates
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any unit size of population that is convenient
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External Validity
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Refers to the generalizability of the findings to the population from which the data have been taken
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Reportable and notifiable
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By law, physicians and other health care providers must report cases of certain diseases, known as
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BFFSS
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State based system that collects data monthly focusing on personal health behaviors
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Vital Statistics
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Used for determining life expectancy
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Vital Events
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Deaths, births, marriages, and divorces
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Monitoring cancer trends is an application of
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Registries
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Surveillance
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Systematic gathering of info about occurrence of a disease and other health phenomena
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Notifiable disease
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diseases that have to be reported to the US Public Health Service HIV
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Descriptive Epi is about
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Person, Place, and Time
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Person variables
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Race, Ethnicity, and gender
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place variables
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climate, zipcode
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Time variables
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duration, how often
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Descriptive epi
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Classifies Uses observational Studies Looks at trends Plans, and evaluation of health Develops hypothesis
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Illness due to a specific disease or health condition is known as
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Morbidity
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The individual whose name is associated with a natural experiment during an outbreak of cholera in London was:
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John Snow
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A method for providing quantitative measurements of risks to health is known as:
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Risk Assessment
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Increases and decreases in the frequency of a disease within a year or over a period of several years are known as:
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Cyclic trends
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Health events that are related in time reflect
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Temporal clustering
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A graphic plotting of the distribution of cases by time of onset is a[n]
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Epidemic curve
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A range of values that with a certain degree of probability contain the population parameter is known as a:
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Confidence interval estimate
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The number of live births during a specified period such as a year per the resident population during the midpoint of the year is the:
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Crude birth rate
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A centralized database for collection of information about diseases such as cancer is known as:
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Registry
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The occurrence in a community or region of cases of an illness, specific health behavior, or other health related events clearly in excess of normal expectancy is known as a(n):
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Epidemic
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The immune fraction Use the following example to answer Question. According to a national survey of asthma: On May 1, 2010, the number of residents in Oklahoma who had been diagnosed with asthma at any time during their life was A. The population on June 30, 2010, was B. During the same year, the number of new cases of asthma was C. The incidence rate of asthma (per 100,000) would be expressed as: If A equals the number of deaths in 2009 and B equals the population at the midpoint of 2009 and C equals the number of persons aged 15-24, then the crude death rate per 100,000 population would be:
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(A/B) x 100,000
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With respect to derivation of hypotheses, a type of association in which the frequency of an outcome increases with the frequency of exposure to a factor is known as:
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Method of concomitant variation
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The physician who determined that a human disease was caused by a specific living organism and proceeded to develop four postulates to demonstrate the association between a microorganism and a disease was:
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Robert Koch
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Operations research illustrates which of the following uses of epidemiology:
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Health Service Use
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All of the following are considered ratios except:
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Time
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The lowest dose at which a particular response occurs is known as the:
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Threshold
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Which factors can decrease and observed prevalence?
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A ; C only
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The term that indicates cases of diseases that occur in a specific geographic region is:
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Spatial clustering
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The systematic and continuous gathering of information about the occurrence of diseases and other health phenomena is known as:
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Public health surveillance
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Studies of the effects of exposure to teratogens have used data from
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Birth Certificates
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The immune fraction Use the following example to answer Question. According to a national survey of asthma: On May 1, 2010, the number of residents in Oklahoma who had been diagnosed with asthma at any time during their life was A. The population on June 30, 2010, was B. During the same year, the number of new cases of asthma was C. The incidence rate of asthma (per 100,000) would be expressed as:
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(C/B) x 100,000
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All of the following are considered vital events EXCEPT
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Graduation
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Prevalence measures do not aid in:
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Determining the risk of disease
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Which of the following sources could be used for determining life expectancy?
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Vital Statistics Cooperative Program
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The process of passing from observations and axioms to generalizations is known as
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Inference
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With respect to derivation of hypothesis, a situation in which all of the factors in two or more domains are the same except for a single factor is known as:
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Method of difference
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A type of correlative association between an exposure and effect is a:
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Dose-relationship
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A type of variable that can have an infinite number of values within a specified range is:
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Continuous
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Those members of the population who are capable of developing a disease or condition are known as:
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The population at risk
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Using health-related data that precede diagnosis and signal a sufficient probability of a case or an outbreak to warrant further public health response is known as:
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Syndromic surveillance
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When the value of one variable increases and the value of a second variable increases, the association is:
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Positive
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Epidemiology searches for associations between exposures and:
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Health Outcomes
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Variation in the occurrence of diseases and other health outcomes in populations relates mots closely to:
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Distribution
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A vaccine that provided immunity to smallpox was created by:
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Edward Jenner
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The probability that an event will occur-an individual will become ill or die within a stated period of time or by a certain age-is known as:
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Risk
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The English anesthesiologist who linked cholera outbreaks to contaminated water and innovated several of the key epidemiologic methods that remain valid and in use today
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John Snow
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The process of defining measurement procedures for the variables used in a study is:
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Operationalization
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The ability of a study to demonstrate an association if one exists is known as:
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Power
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In epidemiology, place variables include:
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Localized occurrence of disease
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Urban diseases and causes of mortality are more likely to be those spread by
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A ; B
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Any factor that brings about change in a health condition or other defined characteristic is known as:
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Determinant
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The immune fraction Use the following example to answer Question. According to a national survey of asthma: On May 1, 2010, the number of residents in Oklahoma who had been diagnosed with asthma at any time during their life was A. The population on June 30, 2010, was B. During the same year, the number of new cases of asthma was C. The incidence rate of asthma (per 100,000) would be expressed as: The point prevalence of asthma (percent) would be expressed as:
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(A/B) x 100
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The time period between initial exposure and a measurable response is known as:
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Latency
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For both males and females, what type of cancer is the leading cause of cancer mortality?
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Lung and bronchus cancer
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Whether a contaminated food such as tomatoes caused an outbreak of gastrointestinal disease is a simple example of: Answer
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Casusal Association
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The number of late fatal deaths after 28 weeks or more of gestation plus infant deaths within 7 days of birth divided by the number of live births plus late fetal deaths during a year is the:
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Perinantal Mortality Rate
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At the top of the asthma surveillance pyramid is
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Mortality
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The ancient Greek who contributed to epidemiology by departing from superstitious reasons for disease outbreaks was:
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Hippocrates
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The number of deaths due to a disease that occurs among persons who are afflicted with the disease is known as:
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Case fatality rate
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Monitoring cancer trends in the U.S. population over time is a major application of:
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Registries
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The category in a frequency distribution that has the highest frequency of cases is known as:
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Mode
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Differences in the occurrence of diseases and adverse health conditions in the population are known as:
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Health disparities
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The number of live births reported in an area during a given time interval divided by the number of women aged 15 to 44 is known as:
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General fertility rate
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A stage that takes place during the early phases of pathogenesis and includes activities that limit the progression of disease:
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Secondary prevention
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For which of the following criteria do epidemiologists need to observe the cause before the effect?
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Temporality
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Which of the following disease outbreaks happened between 1346 and 1352 and claimed up to one-third of the population of Europe:
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Black death
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What is one of the first steps in presenting data after they have been reviewed for accuracy and completeness?
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Count and tabulate cases
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The death of a fetus when it is in the uterus and before it has been delivered is known as:
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Fetal mortality
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When the incidence rate of disease increases, the prevalence will:
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Increase
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Which of the following is NOT considered a use of epidemiology?
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To provide healthcare services to specific individuals
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The web of causation model specifies a type of causal relationship that is:
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Multi-factorial
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When the value of one variable increases and the value of another variable decreases, the association is:
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Negative