Pearson Anatomy and Physiology Chapter 4 – Flashcards
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tissues
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groups of cells similar in structure that perform common or related function
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histology
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study of tissues
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Four basic tissue types:
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epithelial, connective, muscle, nervous
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Fixed:
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tissue is preserved
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Sectioned
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tissue is cut into slices thin enough to transmit light or electrons
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stained
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a dye is used to enhance contrast
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artifacts
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distortions in preserved tissue
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epithelial tissue (epithelium)
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a sheet of cells that covers the body surfaces or lines body cavities
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covering and lining epithelium
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located on external and internal surfaces ex.) skin
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glandular epithelium
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made up of secreting cells that make up the glands of the body
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main functions of epithelial tissue:
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1. protection 2. absorption 3. filtration 4. excretion 5. secretion 6. sensory reception
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characteristics of epithelial tissue:
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1. polarity 2. specialized contacts 3. supported by connective tissues 4. avascular, but innervated 5. regeneration
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apical surface
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upper free surface exposed to body exterior OR the cavity of an internal organ; some have microvilli, some have cilia
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basal surface
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lower attached surface which attaches to basal lamina
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basal lamina
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noncellular, adhesive sheet made of glycoproteins and collagen fibers; holds basal surface of epithelial cells to underlying cells
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epithelial tissues fit closely together and form continuous sheets
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--except for glandular epithelia
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tight junctions and desmosomes
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specialized lateral contact points that bind adjacent epithelial cells together
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reticular lamina
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layer of extracellular material that "belongs to" the underlying connective tissue; made of collagen protein fibers
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basement membrane
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formed by the reticular lamina and basal lamina; -reinforces epithelial sheet, resists stretching, defines the epithelial boundary
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avascular but innervated
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-no blood cells are found -nourished by diffusion -epithelia are supplied by nerve fibers
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regeneration
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replacement of destroyed tissue with same type of tissue
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damage of epithelial cells
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caused by friction and hostile substances; leads to loss of apical-basal polarity and broken lateral contacts; cell division occurs
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squamous
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flattened and scale-like
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cuboidal
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box-like; cube
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columnar
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tall, column-like
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simple epithelia
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single layer thick -absorption, secretion, or filtration
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stratified epithelia
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two or more layers -high abrasion areas where protection is important
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cell is named for:
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the shape in top (apical) layer
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Simple squamous:
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single layer of flattened cells Location: alveoli of lungs Function: rapid diffusion
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endothelium
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simple squamous in lining of lymphatic vessels, blood vessels, and heart
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mesothelium
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simple squamous in lining of serous membranes in the ventral body cavity
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simple cuboidal epithelium
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single layer of cube-like cells; large spherical central nuclei Location: kidney tubules Function: secretion and absorption
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simple columnar epithelium
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single layer of tall cells; round to oval nuclei --may contain goblet cells Location: -nonciliated: digestive tract -ciliated: bronchi Function: absorption, secretion of mucous, propelling mucous or reproductive cells by ciliary action
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goblet cells
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secrete mucous
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stratified squamous epithelia
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many cell layers; basal cells are cuboidal and apical cells are squamous or flat Location: skin Function: protection
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Keratinized stratified squamous
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-outermost layer is dead (no nuclei) and filled with keratin protein -helps to keep skin dry (waterproofer)
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non-keratinized stratified squamous
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-forms linings in ares kept moist -mouth, esophagus, vagina
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stratified cuboidal epithelium
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-rare in the body -typically two layers Location: large glands (sweat, mammary)
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stratified columnar epithelium
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-rare in the body -can occur at junctions between two types of epithelia Location: pharynx, male urethra, lining some glandular ducts
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pseudostratified ciliated columnar epithelium
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-single layer of cells that differ in height --contains goblet cells Location: trachea Function: propel substances (mucous) and secretion of mucous
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transitional epithelium
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-basal cells are cuboidal or columnar -apical cells are dome shaped when relaxed and squamous shaped when distended Location: bladder and urinary system Function: change shape and allow an increase volume of urine
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gland
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one or more cells that make and secrete a product
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secretion
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-aqueous fluid rich in proteins, lipids, or steroids that is the product of glands -process of making and releasing a product
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endocrine
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internally secreting to another site in the body
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exocrine
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externally secreting to a site outside the body
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Endocrine glands = ductless glands
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secretions are released into surrounding interstitial fluid, which is picked up by circulatory system --most are multicellular but some individual cells
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hormones
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messenger chemicals secreted via exocytosis into extracellular space and travel to target organ
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exocrine glands
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secretions are released onto body surfaces or into body cavities; more numerous than endocrine glands -unicellular or multicellular
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Products of exocrine glands:
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mucous, sweat, oil, saliva, bile, digestive enzymes
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Unicellular exocrine gland:
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goblet cells and mucous cells
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mucin
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product of goblet cells or mucous cells that contains a glycoprotein that dissolves in water to form mucus
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mucus
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slimy coating that protects and lubricates (secrete via exocytosis)
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multicellular exocrine glands
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composed of a duct and secretory unit; surrounded by supportive connective tissue -supplies blood and nerve fibers to gland -forms capsule around gland -extends into gland, dividing it into lobes
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tubular gland
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secretory cells from a tube
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alveolar gland
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secretory cells form sacs
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tubuloalveolar
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tube and sacs
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simple glands
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have unbranched ducts
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compound glands
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have branched ducts
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merocrine
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secrete products by exoctyosis as secretions are produced
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holocrine
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accumulate products within, then rupture
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apocrine
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accumulate products withing, but only apex ruptures (not sure if these exist in humans)
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connective tissue
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most abundant and widely distributed of primary tissues
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functions of connective tissue
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1. binding and support 2. protecting 3. insulating 4. storing reserve fuel 5. transporting substances
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exctracellular matrix (ECM)
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made up of ground substance and fibers -non-living -living cells of the tissue are embedded in it -allows connective tissue to bear weight, withstand tension, and endure abuses
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ground substance
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unstructured gel-like material that fills space between cells -interstitial fluid -cell adhesion proteins -proteoglycans (sugar proteins) -water is trapped in varying amounts
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collagen fibers
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strongest and most abundant type -provides high, tensile strength -made up of collagen protein
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elastic fibers
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networks of long, thin, fibers -contain elastin: rubber-like protein -allow for stretch and recoil
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reticular fibers
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short, fine, hgihly branched collagenous fibers -branching forms networks -different chemistry and form from collagen fibers -surround small blood vessels -support soft tissue of organs
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"blast" cells
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immature form -actively mitotic -secrete ground substance and ECM fibers
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fibroblasts
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found in connective tissue proper
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chondroblasts
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found in cartilage
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osteoblasts
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found in bone
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hematopoietic stem cells
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found in bone marrow
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"cyte" cells
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mature form -becomes part of the extracellular matrix -maintains health -less active
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fat cells
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store nutrients
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white blood cells
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tissue response to injury ex.) neutrophils, eosinophils, lymphocytes
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mast cells
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initiate local inflammatory response against foreign microorganisms
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macrophages
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phagocytic cells that "eat" dead cells and microorganisms
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Loose connective tissue types
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-areolar, adipose, reticular
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areolar loose connective tissue
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gel like matrix, all 3 fiber types Location: dermal papilla (under the hypodermis of the skin) Function: acts as a cushion, "packing material" between tissues
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adipose loose connective tissue
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sparse matrix, closely packed fat cells Location: under skin, around organs Function: insulation; support and protection
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reticular loose connective tissue
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loose network of reticular fibers; gel-like ground substance; reticular cells Location: spleen and lymphatic system Function: support of organs
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dense connective tissue types:
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regular, irregular, elastic
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dense regular connective tissue
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parallel collagen fibers, few elastic fibers, fibroblast cells Location: attaches things; tendons and ligaments Function: withstand stress in 1 direction
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dense irregular connective tissue
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irregularly arranged collagen fibers, some elastic fibers, fibroblast cells Location: fibrous capsules of organs and joints (shoulder) Function: withstand tension in multiple directions; structural strength
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dense elastic connective tissue
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dense tissue, high amount of elastic fibers Location: artery walls Function: allows recoil after stretch; maintains blood flow through arteries
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Hyaline cartilage
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most abundant cartilage, matrix appears glassy, chondrocytes lie in lacunae (cavities in the matrix) Location: costal cartilage of ribs Function: support and reinforcement; acts as a cushion; resists compression
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elastic cartilage
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more elastic fibers than hyaline Location: ear Function: maintain shape and structure with ability to flex
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fibrocartilage
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less firm matrix than hyaline, thick collagen fibers, alternating fibers and cells Location: intervertebral discs Function: absorbs compressive shock
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bone tissue
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osteons, lamellae, central canal, hard calcified matrix, collagen fibers Location: bones Function: support and protection, framework
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osteons
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closely packed structural units
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lamellae
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concentric rings of bony matrix
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central canal
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contains blood supply
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bood
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fluid in blood vessels (red and white blood cells, platelets, fluid matrix or plasma) -most atypical connective tissue -doesn't connect things or give support Location: within blood vessels Function: transport gases, nutrients, and wastes
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myofilaments
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networks of actin and myosin filaments in muscle cells; enable movement and contraction
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skeletal muscle
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long, cylindrical cells; multinucleate; striations Location: skeletal muscles attached to bone or skin Function: voluntary movement
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smooth muscle
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spindle shaped cells; elongated; central nuclei; no striations Location: walls of hollow organs (blood vessels, lymphatic vessels, bladder, respiratory tract, digestive tract, iris of the eye) Function: involuntary muscle movement; propel substances along internal passageways by contracting
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cardiac muscle
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branched cells, striated, uninucleate, cells fit together at unique junctions (intercalated discs) Location: walls of the heart Function: involuntary muscle; propels blood when it contracts
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nervous tissue
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made of neurons (branching cells with soma, dendrites, and axon) and glial cells (varied structures that support) Location: brain, spinal cord, nerves Function: -neurons: generate and conduct nerve impulses -dendrites: respond to stimuli and pick up signal -axon: transmits electrical impulses -glial cells: act as a mesh to support, insulate and protect the neurons
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covering and lining membranes
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composed of at least two primary tissue types: an epithelium bound to underlying connective tissue proper layer -cutaneous -mucous -serous
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cutaneous membrane
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(a.k.a. skin) -keratinized stratified squamous epithelium (epidermis) attached to a thick layer of connective tissue (dermis) -dry membrane
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mucous membrane
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(a.k.a. mucosae) line body cavities that are open to the exterior -epithelial sheet lies over layer of loose connective tissue called lamina propria -moist membranes bathed by secretions (ex. urine) -may secrete mucus
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serous membrane
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(a.k.a. serosae) -found in closed ventral body cavities -made of simple squamous epithelium (mesothelium) resting on thin areolar connective tissue -moist membrane (cavity is filled with serous fluid)
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parietal
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line internal body cavity walls
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visceral
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cover internal organs
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pleurae
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lungs
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pericardium
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heart
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peritoneum
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abdomen
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endothelium
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simple squamous in lining of lymphatic vessels, blood vessels, and heart
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mesothelium
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simple squamous in lining of serous membranes in the ventral body cavity
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endothelium
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simple squamous in lining of lymphatic vessels, blood vessels, and heart
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mesothelium
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simple squamous in lining of serous membranes in the ventral body cavity
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endothelium
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simple squamous in lining of lymphatic vessels, blood vessels, and heart