Optional Final – Flashcards
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| Why study Microbiology? |
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| Although very small, microbes play significant roles in our lives. -We have, living on and in our bodies [e.x. skin and in our mouths and intestional tract] approx. 10 times as many microbes as the total number of cells. It has been estimated that perhaps as many as 5,000 to 1,000 different spcies of microbes live on and in us. -these are known as INDIGENOUS MICROFLORA or INDIGENOUS MICROBIOTA and for the most part they benefit us. -Other reasons listed below: >Some of the microbes that colonize [inhabit] our bodies are known as OPPORTUNISTIC PATHOGENS >Microbes are essential for life on this plant as know it because some microbes produce PHOTOSYNTHESIS [note: microbes contribute more oxygen to our atmosphere than do plants.] >Many microbes are invovled in the decomposition of dead organisms and the waste profucts of living organims. Collectively, they are referred to as DECOMPOSERS or SAPROPHYTES >Some micrboes are capable of decomposing industrial wastes [oil spills, for example] - thus, we can use microbes- genetically engineered microbes, in some cases- to clean up after ourselves. The use of microbes in this manner is referred to as BIOREMEDIATION >MICROBIAL ECOLOGY >Microbes serve as important links in food chains. >Some microbes live in the intestional tracts of animals, where they aid in the digestion of food, and in some cases, produce substances that are of value to the host - [e.x. the E.coli bacteria that live in humans intestional tract produce vitamins K and B1] >BIOTECHNOLOGY >Microbes cause two dieases -INFECTIOUS DIEASE AND MICROBIAL INTOXICATION |
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| Define: Opportunistic Pathogens |
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| Do NOT cause diease under ordinary conditions, but have the potential to cause disease should the opportunity present itself. |
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| Define: Microbial Ecology |
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| Study of the interrelationships among microbes and the world around them [other microbes, other living organims, and the nonliving environment] ex. nitrogen cycle |
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| Define: Biotechnology - give an example |
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| The use of living organims or their derivatives to make or modify products or processes e.x. Some bacteria and fungi produce antibiotics that are used to treat patients with infectious diseases. By defintion, and ANTIBIOTIC is a substance produced by a microbe that is effective in killing or inhibiting the growth of other microbes - the use of microbes in the antibiotic industry is an example of biotechnology. |
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| What is the difference between an INFECTIOUS DIEASE and a MICROBIAL INTOXICATION? Which one causes more illnesses and death? |
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| An INFECTIOUS DIEASE results when a pathogen colonizes the body and subsequently causes diease while a MICROBIAL INTOXICATION results when a person ingests a toxin [poisonous substance] that has been produced by a microbe [note:] of the two categories, infectious diseases cause far more illnesses and deaths. |
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| Define: Koch's Postulates |
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| A series of scientific steps, proposed by Robert Koch, that must be fulfilled to prove that a specific microorgansims is the cause of a particular diease. |
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| List the 4 Koch's Postulates |
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| 1. A particular microbe must be found in all cases of the diease and must not be present in healthy animals or humans. 2. The microbe must be isolated from the dieased animal or human and grown in pure culture in the lab. 3. The same diease must be produced when the microbes from the pure culture are imcoluted into healthy susceptible laboratory animals. 4. The same microbe must be recovered from the experimentally infected animals and grown into pure culture. |
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| The sizes of bacteria and protoza are usually expressed in terms of _______? |
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| Micrometers [um] |
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| "Spherical bacterium" [coccus; pl cocci] are approx __________ in diameter? |
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| 1um |
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| A typical "rod-shaped bacterium"[bacillus; pl., bacilli] is about ________? |
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| 1 um wide X 3 um long [note: although som bacilli are shorter and some from very long filaments. |
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| The size of most "virsus" are expressed in terms of _______? |
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| Nanometers [nm] [note] most of the virsus that cause human diease range in size from ~ 10 to 300 nm [0.01-0.3 um] although some such as Ebola virus [a cause of hemorrhagic fever] can be as long as 1,000nm [1um]. Some very large protozoa reach a length of 2,000 um [2mm] |
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| In the microbiology laboratory, the sizes of cellular microbes are measured using an |
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| OCULAR MICROMETER |
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| Microorgansims---> -Cellular -Acellular |
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| -Acellular: >Viroids >Prisons >Viruses -Cellular: >Procaryotes: ---Archaea ---Bacteria ---Cyanobacteria >Eucaryotes ---Algae ---Protozoa ---Fungi |
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| What is the structural difference b/t Procaryotic and Eucaryotic cells |
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| -Eucaryotic cells contain a TRUE NUCLEUS, where as procaryotic cells do not. -Eucaryotic cells are broken down into plant [all plant, fungi, and algae] and animal cells [all animals and protozoa] - animal cells do NOT have a CELL WALL, where as plant cells have a simple cell wall [containing cellulose- a polysaccharide]. -Procaryotic cells have complex CELL WALLS [containing proteins, lipids, and polysaccharides] and can do photosynthesis [chlorophyll] Eucaryotic cells - Membranous structures [e.x. ER and Golgi complexes], Ribosome [80S], Chromosomes [containing DNA and proteins], Flagella and cilia [when present, have a complex structure] Procaryotic cells- no membranous structures other than a cell wall, no nuclear membrane, cytoplasmic ribosome [70S], chromosomes [composed of DNA alone], flagella and cilia [when present, flagella have a simple twisted protein structure, NO CILIA IN PROCARYOTIC CELLS, can do photosynthesis [chlorophyll] |
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| Acellular Microbes: Viruses What are complete virus particles called? |
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| Virons |
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| Acellular Microbes: Viruses How do we observe Viruses? |
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| They are observed using electron microscope |
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| Acellular Microbes: Viruses Most viruses range in size from _____ to _______ nm. Although some- like Ebola virus, can be up to _____um. |
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| 10 to 300; 1 |
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| Acellular Microbes: Viruses The viruses that infect bacteria are known as ? |
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| Bacteriophages [or simply phages] |
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| Bacteriophages can be categorized by the events that occur after invasion of the bacterial cell: some are _________ phages while others are _______ phages |
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| Virulent, temperate |
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| Acellular Microbes: Viruses Define : Virulent bacteriophage |
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| A bacteriophage that regularly causes lysis of the bacteria it infects; causes the lytic cycle to occur [which results in destruction of the cell] |
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| Acellular Microbes: Viruses List the steps in the Lytic cycle |
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| 1. Attachment -the phage attaches to a protein or polysaccharide molecule [receptor] on the surface of the bacterial cell 2. Penetration - the phage injects the DNA into the bacterial cell; the capsid remains on the outer surface of the cell 3. Biosynthesis - phage genes are expressed, resulting in the production of phage pieces or parts [i.e. phage DNA and phage proteins] 4. Assembly - the phage pieces are assembled to create complete phages 5. Release - the complete phage escape from the bacterial cell by lysis of the cell |
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| Acellular Microbes: Viruses Define: Temperate bacteriophage |
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| A bacteriophage whose genome incorporates into and replicates with the genome of the host bacterium; also known as LYSOGENIC BACTERIOPHAGE -unlike virulent bacteriophages, temperate bacteriophages do not immediately initiate the lytic cycle. Their DNA can remain integrated into the host cell's chromosome for generation after generation |
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| Acellular Microbes: Viruses Are viruses considered to be alive? |
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| Because they are not composed of cells, viruses are not considered to be living organisms. They are referred to as acellular microbes or infectious particles |
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| Acellular Microbes: Viruses Viruses are said to have 5 specific properties that distinguish them from living cells |
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| 1. The vast majority of viruses either possess DNA or RNA, unlike living cells that possess both 2. They are unable to replicate [multiply] on their own 3.Unlike cells, they do not divide by binary fission, mitosis, or meiosis 4. They lack the genes and enzymes for energy production 5. They depend on ribosomes, enzymes, and metabolites "building blocks" of the host cell for protein and nucleic acid production |
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| The simplest of human viruses consists of nothing more than _________ surrounded by a protein coat [the capsid -which is composed of small protein units called capsomeres] plus to enclosed ______ are referred to as the __________ |
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| Nucleic acid, nucleic acid, nucleocapsid |
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| Defind Viroids. |
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| Viroids consist of short, naked fragments of single-stranded RNA that can interfere with with the metabolism of plant cells and stunt the growth of plants, sometimes killing the plants -Small circular, naked RNA -Smallest known pathogens -Viroids are infectious RNA molecules that cause a variety of plant disease. **** |
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| Define : Prions |
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| Prions are infectious protein molecules that cause a variety of animal and human diseases. |
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| Study table 4-16 page 54 |
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| Differences between Gram-positive and Gram-negative bacteria |
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| -Gram- positive: >blue/purple >thick peptidoglycan in cell walls >teichoic acids and lipoteichoic acids in cell walls >NO lipopolysaccharide in cell walls -Gram-negative: >Pink/red >Thin layer of peptidoglycan > NO teichoic acid and lipoteichoic acids in cell walls > Lipopolysaccharide in cell walls |
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| Algae and protozoa are referred to as __________ because they are in the kingdom Protista |
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| protists |
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| Define:Algea and give characteristics |
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| Eucaryotic, photosynthetic organisms that range in size from unicellular to multicellular; includes many seaweeds. All algal cells consists of cytoplasm, a cell wall [usually], a cell membrane, a nucleus, plastids, ribosomes, mitochondria, and Golgi bodies. >in addition some contain pellicle [thicken cell membrane], a stigma [light sensing organelle, known as an eye spot] and flagella. note: Contain chlorophyll Oxygenic photosynthesis -although not plants - more closely plantlike than protozoa --ALGAE LACK TRUE ROOTS, STEMS, AND LEAVES |
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| Define: Protozoa and give characteristics |
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| Eucaryotic microorganisms frequently found in water and soil [ free-living] some are pathogens; usually unicellular all possess a variety of eucaryotic structures and organelles, including cell membranes, nuclei, endoplasmic reticulum, mitochondria, Golgi bodies, lysosomes, centrioles, and food vacuoles PROTOZOA HAVE NO CHLOROPHYLL AND THEREFORE CANNOT MAKE IT'S OWN FOOD BY PHOTOSYNTHESIS. |
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| Define: Fungi and give characteristics |
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| Eucaryotic, nonphotosynthetic microorganisms that can be either saprophytic or parasitic Fungi are found almost everywhere on earth; some [the saprophytic fungi] living on organic matter in water and soil, and others [parasitic fungi] living on and within animals and plants. NOT PHOTOSYNTHETIC; HAVE NO CHLOROPHYLL OR OTHER PHOTOSYNTHETIC PIGMENTS |
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| Define: The Central Dogma define and name who proposed it |
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| The flow of genetic information within a cell; from DNA to an mRNA molecule to a protein molecule Francis Crick 1957 |
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| The Central Dogma [also known as the "one geneone protein hypothesis'] states that: [hint: 2 things] |
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| 1. The genetic information contained in one gene of a DNA molecule is used to make one molecule of mRNA by a process known as TRANSCRIPTION 2. The genetic information in that mRNA molecule is then used to make one protein by a process known as TRANSLATION |
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| Define: phototrophs |
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| organisms that use light as an energy source |
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| Define: Chemotrophs |
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| organims that use inorganic or organic chemicals as an energy source |
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| Note: Chemotrophs use either inorganic or organic chemicals and can be subdivided into two categories >chemolithotrophs >chemorganotrophs |
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| >Chemolithotrophs [or simply lithotrophs] : are organisms that use inorganic chemicals as an energy source >Chemoorganotrophs [or simply organotrophs] are organims that use organic chemicals as an energy source |
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| Define: Autotrophs |
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| organisms that use C02 as a carbon source |
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| Define: Heterotrophs |
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| organisms that use organic compounds other than CO2 as their carbon source |
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| Define: photoautrotrophs give examples |
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| are organisms that use light as an energy source and CO2 as a carbon source -some examples: plants, algae, cyanobacteria, purple and green sulfur bacteria] |
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| Define: Photoheterotrophs |
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| use like as an energy source and organic compounds other than carbon dioxide as a carbon source |
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| Define: Chemoautrophs |
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| use chemicals as energy and carbon dioxide as a carbon source |
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| Define: Chemohetertrophs |
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| Use chemicals as an energy source and organic compounds other than C02 as an energy source |
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| Define: Mutations |
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| involve changes in the base sequences of genes |
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| Define: Beneficial Mutations |
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| are mutations that are beneficial to the organisms |
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| Define: Harmful Mutations |
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| A mutation that leads to the production of a non-functional enzyme -If this causes the cell to die- then it leads to LETHAL Mutation |
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| Define: Silent [Neutral] Mutation |
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| A mutation that has no effect on the cell |
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| Define: Spontaneous Mutation |
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| Random mutations that occur naturally |
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| Define: Mutagens |
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| Physical or chemical agents that cause increase an mutation rate ex. e-ray, ultraviolet light |
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| Define: Spontaneous Mutation |
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| Random mutations that occur naturally |
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| Define: Mutagens |
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| Physical or chemical agents that cause increase an mutation rate ex. e-ray, ultraviolet light |
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| Define: Thermophiles |
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| Microorganisms that grow best at high temperatures Minimm growth temperature: 25 oC Optimum growth temperature: 50-60 oC Maximum Growth Temperature: 113 oC |
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| Define: Mesophiles |
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| Microbes that grow best at moderate temperatures Min growth temp: 10 oC Opt growth temp: 20-40 oC Max growth temp: 45 oC |
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| Define: Psychrophiles |
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| organisms that "love" cold temperature Min growth temp: -5 oC Opt growth temp: 10-20 oC Max growth temp: 30 oC |
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| Define: Chemically defined medium |
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| all the ingredients are known - this is because the medium was prepared in the lab. |
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| Define: Complex Medium |
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| One in which the exact contents are not known. Complex media contains ground up or digested extracts from animal organs which provide the necessary nutrients, vitamins, and minerals. |
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| Define: Enriched Medium |
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| A broth or solid medium containing a rich supply of special nutrients that promotes the growth of fastidious organisms |
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| Define: Selective Medium |
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| Has added inhibitors that discourage the growth of certain organisms without inhibiting growth of the organism being sought. |
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| Define: Differential medium |
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| allows one to readly differentiate among the various types of organisms that are growing on the medium. |
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| Mannitol salt gar is used to screen for S. aureus. not only will S. aureus grow on MSA but it turns the orginally ________ medium to ________ because of it's ability to ferment mannitol. |
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| Pink, yellow |
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| Define: Population Growth Curve |
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| A bacterial population growth curve consists of four phases: a lag phase, a log phase, a stationary phase, and a death phase. |
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| Inhibiting the Growth of Microorganisms in Vitro Define: Sterilization |
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| Sterilization involves the destruction or elimination of all microbes [ including cells, spores, and viruses] -[note]: when something is sterile, it is devoid of microbial life. |
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| Define: Disinfection |
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| involves the elimination of most or all pathogens [except bacterial spores] from nonliving objects |
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| Define: Pasteurization |
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| a method of disinfecting liquids |
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| Chemicals used to disinfect inanimate objects, such as beside equipment and operating rooms are called |
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| Disinfectants |
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| Define: Antiseptics |
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| solutions used to disinfect skin and other living tissues |
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| Define: Sanitization |
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| the reduction of microbial population to levels considered safe by public health standards, such as those applied to restaurants. |
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| Agents having the suffix "-cidial" or "cide" kill organisms whereas agents having the suffix "-static" merely mean ______ |
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| inhibit the growth and reproduction |
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| Define: germicidal agent |
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| a chemical agent or drug that kills pathogens |
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| Define: Biocidal Agent |
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| A chemical agent that destroys living organisms |
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| Define: Microbicidal Agent |
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| A chemical or drug that kills microorganisms |
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| Define: Bactericidal Agent |
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| A chemical that kills bacteria |
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| Define: Sporicidal Agent |
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| A chemical or drug that kills spores |
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| Define: Fungicidal Agents |
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| A chemical or drug that kills fungi, including fungal spores |
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| Define: Algicidal Agents |
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| A chemical or bacteria that to kill algae in swimming pools and hot tubs |
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| Define: Viricidal Agents |
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| A chemical or drug that destroys viruses |
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| Define:Microbistatic Agent |
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| A drug or chemical that inhibits reproduction or microorganisms, but does not necessarily kill them |
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| Define: Bacteriostatic Agent |
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| one that specifically inhibits the metabolism and reproduction of bacteria. |
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| Define: Lyophilization |
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| a good method of preserving microorganisms for future use |
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| Define: Sepsis verse Asepsis |
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| Sepsis is the presence of pathogens in blood or tissue where Asepsis the absence of pathogens in blood or tissue |
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| Define: Aseptic techniques |
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| Eliminate and exclude pathogens |
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| Define: Antisepsis Antiseptic technique Who created this technique ? |
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| Antisepsis: The prevention of infection Antisepsis Technique: the use of antiseptics -John Lister in 1867 |
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| What is the most common type of sterilization for inanimate objects able to withstand high temperatures? |
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| HEAT |
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| Explain: Thermal Death Point [TDP] verse Thermal Death Time [TDT] |
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| TDP is the lowest temp. that will kill all the organisms in a standard pure culture within a specified period TDT is the length of time necessary to sterilized a pure culture at a specified temp |
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| Define Autoclave |
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| large, metal pressure cooker that uses steam to destroy all microbial life |
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| TRUE OR FALSE. Most organisms are not killed by cold temperature. |
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| True, instead their metabolic activities are slowed. |
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| Define: Chemotherapeutic Agent |
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| ANY drug used to treat ANY condition or disease |
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| The chemotherapueutic agents used to treat infectious diseases are collectively referred to as ____________ |
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| Antimicrobial Agents [thus, an antimicrobial agent is any chemical [drug] used to treat infectious disease, either by inhibiting or killing pathogens in vivo. |
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| Define: Antibiotic |
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| a substance produced by a microorganism that is effective in killing or inhibiting the growth of other microorganisms |
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| TRUE OR FALSE: all antibiotic antimicrobial agents are antibiotics |
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| False. Although all antibiotics are antimicrobial agents, not all antimicrobial agents are antibiotics. |
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| TRUE OR FALSE: Antibiotics are primarily antibacterial agents and are thus used to treat bacterial diseases. |
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| True |
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| Who discovered Penicillium? [and the first antibiotic] |
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| Alexander Fleming |
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| What are the characteristics of an ideal antimicrobial agent? |
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| -Kill or inhibit the growth of pathogens -Cause no damage to the host -Cause no allergic reaction to the host -Be stable when stored in a solid or liquid form -Remain in specific tissues in the body long enough to be effective -Kill the pathogens before they mutate and become resistant to it |
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| What is the difference between Synergism versus Antagonism |
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| When the use of two antimicrobial agents to treat an infectious disease produces a degree of pathogen killing that is far greater than that achieved by either drug alone, the phenomenon is known as SYNERGISM- when the use of two drugs produces an extent of pathogens killing that is less than that achieved by either drug alone, the phenomenon is known as ANTAGONISM |
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| Mechanisms by which bacteria become resistant to antimicrobial agents table 9-7 |
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| Define: Empiric Therapy |
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| An educated guess a physician makes - tells the pathogen and what medicine to perscribe before the acutal results come in |
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| What are some factors a physician must take in beofre he perscribes a medication based on empric therapy? |
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| -If the lab has the idenity of the pathogen, the clinician can refer to a pocket chart -is the patient allergic to any antimicrobial agents -What is the age of the patient -is the patient prego -is the paitient and inpatient or outpatient-what is the site of the patient infection |
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| Define: Symbiosis |
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| the living together or close association of two dissimilar organisms [usually two different species] |
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| Define: Neutralism |
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| used to describe a symbiotic relationship in which neither symbiotic is affected by the relationship. |
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| Define: Neutralism |
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| used to describe a symbiotic relationship in which neither symbiotic is affected by the relationship. |
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| Define: Microbial ecology |
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| the study of numerous interrelationships between microorganisms and the world around them |
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| Define: Commernsalism |
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| a symbiotic relationship that is beneficial to one symbiont and of no consequence [is not neither beneficial nor harmful] to the other |
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| Define: Mutualism |
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| a symbiotic relationship that is beneficial to both symbionts [i.e. the relationship is mutually beneficial] |
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| Define: Parasitism |
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| a symbiotic relationship that is beneficial to one symbiont [the parasite] and detrimental to the other symbiont [the host] |
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| TRUE OR FALSE: A person's indigenous microflora or indigenous microbiota [sometimes referred to as "normal flora"] includes all of the microbes [bacteria. fungi, protozoa, and viruses] that reside on and within that person |
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| TRUE |
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| It is estamated that our indigenous microflora is composed of between ________ and _____ different species |
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| 500 and 1,000 |
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| How many microbes live withing our bodies? |
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| 100 trillion |
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| TRUE OR FALSE: A fetus has indigenous microflora? |
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| FALSE |
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| Define: Microbial Antagonism |
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| Many members of our indigenous microflora serve a beneficial role by preventing other microbes from becomming established in or colonizing a particular anatomic location |
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| Define: Opportunistic Pathogens |
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| can be thought of as organisms hanging around, awaiting the opportunity to cause infections |
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| Name two vitamins we obtain from intestinal bacteria |
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| K and B12 |
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| Define: Biotherapeutic agents [or probiotics] |
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| Bacteria and yeasts that are ingested to restablish and stabilize the miccrobial balance within our bodies |
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| Define: Communicable disease |
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| If the infectious disease is transmissible from one human to another |
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| Define: Contagious disease |
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| a communicable disese that is easily transmitted from one person to another |
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| Define: Zoonotic Disease |
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| onfectious diseases that human acquire from animal sources |
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| Define: Incidence |
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| # of new cases of that disease |
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| Define: Mortality rate |
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| the ratio of the number of people wo died of a particular disease during a specified time per a specified population. also known as DEATH RATE |
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| Define: Morbidity rate |
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| the number of new cases of a particular disease during a specified time period per specifically defined population |
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| Difference bt Sporadic disease and endemic disease |
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| A sporadic disease is a disease that occurs only occasionally [sporadically] within a population of a particular geographic area, whereas an endemic disease that is always present within a population |
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| Define: Epidemic Disease |
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| diseases that occur in a greater than usual number of cases in a particular region, and usually occur within a relatively short period of time |
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| Name the chain of infections [hint 6] |
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| 1. A pathogen 2. a reservoir of infection 3. a portal of exit 4. a mode of transmission 5. a portal of entry 6. a susceptible host |
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| Define: Healthcare-associated infections [HAIs] |
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| infections that are acquired WITHIN hostipals or other healthcare facilities |
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| Define: Community-Acquired Infections [how many days?] |
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| infections that are acquired OUTSIDE of healthcare facilities -can be as long as up to 14 days of hostipal discharge |
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| In the United States, approximately __% of hospitzlized patients develop HAIs |
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| 5 |
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| 3 components of specimen quality are |
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| 1. proper specimen selection [i.e. the correct type of specimen must be submitted] 2. prooper specimen collection 3. proper transport of the specimen to the lab |
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| It has often been stated that the quality of the lab work performed in a CML can be only as good as the quality of the speciemns it receives - what does this mean? |
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| high-quality clinical specimens are required to achieve accurate, clinically relevant lab. results |
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| In general usage, the terms infection and infectious disease are _______ |
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| synonyms ex. the person has a ear infection same thing as say.. the person has an infectious disease of the ear [hint: infectious disease- disease cause by a microbe] |
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| Many microbiologists, however, reserve use of the word infection to mean? |
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| colonization by a pathogen [i.e. when a pathogen lands on or enters a persons body and establishes residence there, then the person is infected with that pathogen |
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| Four Periods in the Course of an Infectious Disease explain what happens |
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| [a] incubation period [b] prodromal period [c]period of illness [d] convalescent |
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| Define: host cell mechanisms how many lines of defenses does the body have? |
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| wyas in which the body protects itself from pathogens -3 , the first two lines are nospecific and the third line of defense is specific |
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| First line of defense: Skin and Mucous Membranes as Physical Barriers and cellular and chamical factors |
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| intact skin and mucous membranes serve as nonspecific host defense mechanisms by serving as physical or mechanical barriers - the dryness, acidity, and temperature of the skin inhibit colonization and growth of pathogens; perspiration flushes them away. |
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| Define: Microbial anatagonism |
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| When indigenous microflora prevent the establishment of arriving pathogens |
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| The body normally responds to any local injury, irritation, microbial invasion, or bacterial toxin by a complex series of events collectively reffered to as ... |
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| Inflammation |
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| The three major events in acute inflammation |
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| Increase in capillary diameter Increased permeability of capillaries Egress of leukocytes |
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| Define: Immunology |
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| is the scientific study of the immune system and immune response |
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| The immune system is considered to be a specific host defense mechanism and the _______ line of defense |
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| Define: Immunity |
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| resistance to infection |
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| What are the two major arms of the immune system ? define them |
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| Humoral Immunity - always involves the production of antibodies Cell-Mediated Immuninty- involes various cell types, with antibodies playing on a minor roll |
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| Define: acuired immunity |
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| Immunity that results from the active production or receipt of productive antibodies during one's lifetime |
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| [acquired immunity] - if the antibodies are actually produced within the person's body the immunity is called _______ but if the person recives antibodies that were produced by another person or by more than one person, or, in some cases by an animal- such protection is usually only temporary. |
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| Active acquired Immunity ; passive acquired immunity |
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| Two Types of Active Acquired Immunity |
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| Natural- immunity that is acquired in response to the entry of a live pathogen into the body [i.e. in response to an actual infection] Artificial -immunity that is acquired in response to VACCINES |
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| Two Types of Passive Acquired Immunity |
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| Natural immunity that is acquired by a fetus when it recives maternal antibodies in the utero or by an infant when it recives its maternal antibodies contained in colostrum Artificial passive acquired immunity - immunity that is acquired when a person recives antibodies contained in antisera or gamma globulin |
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| Where do immune responses occur? |
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| immune responses occur at many body sites, including the spleen, lymph nodes, tonsils and adenoids |
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| Define: Antigens |
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| foreign organic substances that are large enough to stimulate the production on antibodies |
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| Individual molecues that stimulate the production of antibodies are referred to as |
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| Antigenic determinants or epitopes |
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| The cells that secrete antibodies are called? |
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| plasma cells; they are derived from B cells |
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| Define Epidermis |
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| the superficial portion of the skin |
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| Define Dermis |
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| the inner layer of the skin, containing blood and lympathic vessels, nerves, glands, and hair follicles |
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| Define Dermatitis |
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| inflammation of the skin |
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| Define Sebacous glands |
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| glands in the dermis that usually open into hair follicles and secrete an oily substance known as SEBUM |
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| Define Follicultitis |
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| Inflammation of a hair follicle,the sac that contains a hair shaft |
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| Define Sty |
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| Inflammation of a sebacous gland that opens into a follicle of an eyelash |
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| Define Furncle |
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| A localized pyogenic (pus producing) infection of the skin also known as a BOIL |
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| Define Carbuncle |
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| A deep seated pyogenic infection of the skin |
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| Chickenpox. Reservior & Mode of Transmission |
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| Reservior: Infected humans Transmission: person to person contact or droplet/airborne spread |
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| Rubella (German Measles) Reservior & Transmission |
answer
| Res: infected humans Trans: droplet spread or direct contact w/ nasophyrengeal secretions |
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| Rubeola (Measles) Reservior & Transmission |
answer
| Reser: Infected humans Trans: airborner, droplet, direct person-person |
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| Staphyloccal Skin Infections Res & Trans |
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| R: Infected Humans Trans: person w/ draining lesion or any discharge |
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| Streptococcal Skin. Res & Trans |
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| Res: Infected Humans Trans: person to person via large respiratory droplets or direct contact with patients |
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| Trachoma (Chlamydia Keratoconjuntivitis) Pathogen |
answer
| C. Trachomatis |
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| Gonoccal Conjunctivitis (Gonorheal Ophtalmia) Pathogen? |
answer
| N. Gonorrhease or GC |
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| Streptoccal Pharyngitis ( Strep Throat) Pathogen |
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| Streptococcus pyogenes aka Strep A |
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| Legionellosis Pathogen, Reservior, Transmission |
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| Legionella Pneumophilia Environmental water sources Trans: Aerosols produced by misting devices |
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| Tuberculosis Pathogen, Reservior, Transmission |
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| Mycobacterium tuberculosis Infected Humans, rarely primates and cattle Ariborne droplet |
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| Whopping Cough (Pertusis) Pathogen? |
answer
| Bordetella Pertusis |
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| Campylobacter Enteritis Reservior and Transmission |
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| Res: animals including poultry Trans: contaminated foods, raw milk, cutting boards |
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| Salmonellosis Reservior and Transmission |
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| Res: wild and domestic animales Trans: Contaminated food, beef, cattle, milk |
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| Influenza (Flu) Reservior & Transmission |
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| Res: Infected humans, pigs, birds Trans: Ariborne spread and direct contact |
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| Avian Influenza (Bird Flu) |
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| Note: Caused by Influenza A only Res: infected wild and domesticated birds Trans: Bird to human via infected poultry or surfaces |
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| Define Colitis |
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| Inflammation of the colon |
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| Define Dysentry |
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| frequent watery stools |
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| Define Enteritis |
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| Inflammation of the intestines, usually referring to the small intestine |
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| Define Gastritis |
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| inflammation of the stomach |
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| Define Hepatitis |
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| Inflammation of the liver |
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| UTI. Lower vs Upper Tract |
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| Lower Tract: Bladder (Cystitis), Urethra, and Prostate Upper Tract: Kidneys(Nephritis) and Ureters |
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| Define Endocarditis |
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| Inflammation of the membrane that lines the cavaties of the heart |
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| Define Myocardium |
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| Inflammatoin of the muscular walls of the heart |
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| What does the CNS consists of? |
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| Brain, the spinal cord, and the meninges |
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| Define encephalitis |
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| inflammation of the brain |
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| Define Myelitis |
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| Inflammation of the spinal cord |
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| What causes meningitis? |
answer
| Ingestion of poisons, drugs, vaccines, or a pathogen |
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| True or False. Viral Meningitis is sometimes referred to "aseptic meningitis" |
answer
| TRUE |
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| What percentage of Trichanomas is caused by vaginitis? |
answer
| 1/3 |
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| Giardiasis. Res & Trans |
answer
| Res: Infected humans, possibly beavers and other animals that have ingested water containing giardia cysts Trans: fecal-orals, conataminated water, person to person |