MLT 250 Hematology Practice Exam Questions – Flashcards
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Each of the following samples may be used in hematology except: a. serum from a clot tube b. EDTA whole blood c. Sodium citrate whole blood d. Heparinized capillary blood
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a. serum from a clot tube
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A 1:200 dilution of a patient's sample was made and 336 red cells were counted in an area of 0.2 mm2. What is the RBC count? a. 1.68 x 1012/L b. 3.36 x 1012/L c. 4.47 x 1012/L d. 6.16 x 1012/L
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b. 3.36 x 1012/L
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Which one of the following conditions will most likely lead to hypoxia? a. methemoglobinemia b. bacteremia c. acidosis d. high levels of 2,3-BPG
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a. methemoglobinemia
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Which of the following cells are normally present in a normal blood specimen? a) RBC, PLT, lymphs, neutrophils, blasts and monocytes b) RBC, PLT, lymphs, neutrophils, monocytes, eos, basos, a few bands and a few polychromatopilic RBC c) RBC, PLT, megakaryocytes, promyelocytes, reactive lymphocytes, toxic bands and PMN d) RBC, NRBC, blasts, monos, eos, basos and PMNs
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b) RBC, PLT, lymphs, neutrophils, monocytes, eos, basos, a few bands and a few polychromatopilic RBC
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Reticulocytes are the same as polychromatophilic erythrocytes (RBC exhibiting polychromasia). True or False?
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True
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ALL morphological characteristics studied in this lesson can be identified in Wright's stained blood smears. True or False?
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False- Pappenheimer bodies need Prussian stain reticulocytes need vital stain (new methylene blue)
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What is the M:E ratio found in a normal bone marrow? a) approximatelly 3:1 b) approximatelly 1:3 c) 1:1 d) 2:3
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a) approximatelly 3:1
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1. Which of the following red cell indices reflects the amount of hemoglobin per individual red cell? a) Hgb b) MCV c) MCHC d) MCH
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d) MCH
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2. A blood sample that has moderate anisocytosis with moderate macrocytes is expected to have? a) a MCHC greater than 37% b) a MCV greater than 100 fL c) a MCH greater than 32 pg d) normal red cell indices
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b) a MCV greater than 100 fL
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Which of the following morphological classifications best describes the hemolytic anemias: a. microcytic, hypochromic b. normocytic, hypochromic c. normocytic, normochromic d. macrocytic, normochromic e. macrocytic, hypochromic
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c. normocytic, normochromic
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An osmotic fragility test shows initial hemolysis of the red cells at 0.70 % NaCl. This is most consistent with: a. Hereditary spherocytosis b. Hereditary ovalocytosis c. G6PD deficiency d. Paroxysmal Cold Hemoglobinuria
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a. Hereditary spherocytosis
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One of the following best indicates intravascular hemolysis a. increased serum bilirubin b. increased urine bilirubin c. increased reticulocytes d. hemoglobinuria
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d. hemoglobinuria
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1. One of the following may lead to pernicious anemia: a. Gastric resection b. Strict vegan diet c. Diphyllobothrium latum infection d. Pregnancy
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a. Gastric resection PA is due to lack of intrinsic factor which is made by gastric mucosa (parietal cells)
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2. The aplastic anemias may be classified by which morphological group? a. Normocytic/Normochromic b. Macrocytic/Normochromic c. Megaloblastic/Normochromic d. Microcytic/Hypochromic
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a. Normocytic/Normochromic like hemolytic
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3. One of the following statements regarding IDA is NOT true: a. Serum iron and ferritin levels are low, TIBC is high b. Reticulocyte counts will be low c. RDW will be high d. Microcytic & hypochromic cells will be observed with relatively little deficiency
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d. Microcytic & hypochromic cells will be observed with relatively little deficiency
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Which if the following hemoglobins rank second in variant hemoglobins worldwide? a) Hgb S b) Hgb E c) Hgb H d) Hgb C
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d) Hgb C
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Which hemoglobin will show crystals appearing like bars of gold in the peripheral smear? a) Hemoglobin CC disease b) Hemoglobin DD disease c) hemoglobin EE disease d) hemoglobin SS disease
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a) Hemoglobin CC disease
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Of the four clinical states of alpha thalassemia, which is incompatible with life? a) alpha thalassemia silent carrier b) alpha thalassemia trait c) hemoglobin H disease d) Hydrops Barts fetalis
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b) alpha thalassemia trait
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What is the majority hemoglobin in thalassemia major? a) Hemoglobin A b) hemoglobin A2 c) hemoglobin F d) hemoglobin H
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c) hemoglobin F
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How many blast cells in the bone marrow aspirate smear are necessary for a diagnosis of acute leukemia using the WHO criteria? a) 20% b) 10% c) 30% d) none of the above
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c) 20%
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Which cytochemical reactions would you expect from an Acute Myelomonocytic Leukemia? a) MPO positive SBB negative b) MPO, SBB, NASDA, ANAE positive, PAS negative c) MPO, SBB positive, NASDA and ANBE negative d) MPO, NASDA and PAS negative
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b) MPO, SBB, NASDA, ANAE positive, PAS negative
