Missense Mutations – Flashcards

Unlock all answers in this set

Unlock answers
question
Missense mutations
answer
Code for a different amino acid. A missense mutation changes a codon so that a different protein is created, a non-synonymous change.
question
Conservative mutations:
answer
Result in an amino acid change. However, the properties of the amino acid remain the same (e.g., hydrophobic, hydrophilic, etc). At times, a change to one amino acid in the protein is not detrimental to the organism as a whole. Most proteins can withstand one or two point mutations before their functioning changes.
question
Non-conservative mutations
answer
Result in an amino acid change that has different properties than the wild type. The protein may lose its function, which can result in a disease in the organism.
question
Non-conservative mutations
answer
Result in an amino acid change that has different properties than the wild type. The protein may lose its function, which can result in a disease in the organism.
question
Silent mutations
answer
Code for the same amino acid. A silent mutation has no effect on the functioning of the genome. A single nucleotide can change, but the new codon specifies the same amino acid, resulting in an unmutated codon.
question
Silent mutations
answer
Code for the same amino acid. A silent mutation has no effect on the functioning of the genome. A single nucleotide can change, but the new codon specifies the same amino acid, resulting in an unmutated codon.
question
Silent mutations
answer
Code for the same amino acid. A silent mutation has no effect on the functioning of the genome. A single nucleotide can change, but the new codon specifies the same amino acid, resulting in an unmutated codon.
Get an explanation on any task
Get unstuck with the help of our AI assistant in seconds
New