Micro Block 3 Flashcard
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| tinea versicolor |
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| malassezia furfur (superficial) |
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| dark spots on light colored skin |
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tinea versicolor (malassezia furfur)
(used in selsum blue shampoo) |
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| spaghetti and meatballs on KOH |
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| tinea versicolor (malassezia furfur) |
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| fungi CW made of: |
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| chitin |
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| fungi CM has: |
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| ergosterol (site of action for anti fungal drugs) |
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| ergosterol is the site of: |
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| action for azoles (ketoconazole, itraconazole |
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| KOH shows hyphae |
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| tinea (capitis, barbae, pedis, corporis) |
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| ringworm |
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| tinea corporis |
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| athletes foot |
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| tinea pedis |
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| rose gardener's disease |
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| sporothrix schenckii (subcutaneous) |
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| cigar shaped OR daisy petal shaped yeast |
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| sporothrix schenckii (subcutaneous) |
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broad based budding (snowman appearance) |
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| blastomyces dermatitidis (systemic) |
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| mississippi and Ohio |
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| blastomyces and histoplasmosis (both systemic/endemic) |
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| LARGE spherule with endospore |
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| coccidoides immitis |
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| caused by inhaling arthrospores |
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| coccidoides immitis |
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| yeast INSIDE macrophages |
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| histoplasmosis |
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| bird or bat droppings |
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| histoplasmosis |
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| pilot's wheel budding |
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| paracoccidiodes brasiliensis |
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| oval yeast with a single bud |
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| candida |
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| opportunistic spores: |
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| 1. candida 2. aspergillus fumigatus 3.pneumocystic jirovicii 4. cryptococcosis neoformans 5. zygomycoses (mucor and rhizomes) |
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| thrush (plaque in oral cavity) |
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| candida |
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| pseudohyphae |
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| candida |
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| candida |
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thrush, (1) oval yeast w/ a single bud, (2) pseudohyphae, (3) germ tubes skin lesions, chronic mucocutaneous candidiasis, vaginitis |
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| esophagitis, endocarditis, vaginitis |
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| candida |
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| germ tubes |
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| candida |
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| ABPA |
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| type 1 IgE hypersensitiviy reaction from aspergillis |
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| "fungal ball" |
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| aka aspergilloma. aspergillosis |
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| TB cavity |
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| aspergillosis |
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| septate V-shaped hyphae |
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| aspergillosis |
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| aspergillosis fumigatus |
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| ABPA by inhalation, septate V-shaped hyphae, fungus ball (aspergilloma) or TB cavity |
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| cryptococcosis neoformans |
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| most common cause of fungal meningitis pigeon feces polysaccharide capsule (only 1 w/ capsule) india ink stains capsule inhaled and spread via blood |
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| fungal meningitis |
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| cryptococcosis neoformans |
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| pigeon feces |
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| cryptococcosis neoformans |
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| india ink stains capsule |
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| cryptococcosis neoformans |
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| polysaccharide capsule (only fungi w/ capsule) |
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| cryptococcosis neoformans |
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| zygomycoses (mucor and rhizomes) |
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mucormycosis diabetic ketoacidosis non-septate hyphae at right angles inhalation via airborne sporangiospores (in a sac) cause rhinocerebral infection, cranial nerve palsy |
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| diabetic ketoacidosis |
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| zygomycoses (mucor and rhizomes) |
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| inhalation via airborne sporangiospores (in a sac) |
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| zygomycoses (mucor and rhizomes) |
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| rizopus |
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| unbranched hyphae |
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| mucor |
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| non septate |
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| candida effects: |
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| skin lesions, mucocutaneous candidiasis, vaginitis |
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| zygomycoses causes: |
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1. cranial nerve palsy 2. rhinocerebral infection 3. DKA |
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| KOH dissolves everything on malessezia furfur except |
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| yeast or hyphae wall |
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| trichophyton schoenleinii: |
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| (tinea favosa) highly infectious, many result in permanent hair loss |
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| fungus affecting the toes |
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| tinea unguium |
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| ringworm affeting bare skin |
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| tinea corporis |
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| W1 antigen action and which fungi |
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| blastomyces. sheds to act as IgG decoy |
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| estrogen stimulates which and inhibits which fungi |
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| stimulates coccidioides bc it produces an estrogen binding protein. DANGEROUS in 3rd-trimester preg. women inhibits paracoccioides |
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| SOWgp action and which fungi: |
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| coccidioides. SOWgp produces a halo around the endospore using UREASE |
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| which fungi has an IgA protease |
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| coccidioidies |
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| accumulation of iron and calcium by which fungi: |
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| histoplasmosis |
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| GP43 is dominant antigen in which fungi: |
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| paracoccidiodes |
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| southwest USA: |
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| coccidioides |
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| penicillum marneffei: |
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| thick transverse septum; contagious lesions on the face and trunk |
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| sordarin use and MoA; |
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| anti fungal drug which inhibits EEF; used for pneumocystis jirovicii |
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| which fungi produces melanin and hows it work |
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| cryptococcus neoformans; melanin neutralizes the free radicals from the macrophage |
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| griseofulvin MoA: |
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| microtubule inhibitor that blocks cell division |
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| mucicarmine stain: |
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| sdetects capsular material- cryptococcus neoformans stains acidic mucins |
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| PAS stain: |
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| stains glycogen and mucin; used for dermatophytes |
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| GMS stain |
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| stains silver; used for pneumocystis cairn |
