IV Meds – Flashcard
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cefazolin sodium
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Ancef & Kefzol
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Ancef & Kefzol: Dosage & Frequency
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1 GM 30-60 minutes before sugery then 1 GM Q 6-8 hours for 24 hours post-op
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Ancef & Kefzol: Uses
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Perioperative Prophylaxis Bone/Joint/Septicemia
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Ancef & Kefzol: Side Effects
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Diarrhea Rash Phlebitis Thromboplebitis
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Ancef & Kefzol: Nursing Considerations
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C&S before 1st dose Stable for 24 hrs @ room temp 96 hrs refrigerated Monitor IV site
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cefazolin sodium/Ancef/Kefzol: Classification
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Cephalosporin
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ceftriaxone sodium
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Rocephin
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ceftriaxone sodium/Rocephin: Classification
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Cephalosporin
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Rocephin: Dosage & Frequency
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1-2 GM IV once per day or in equally divided doses q 12 hrs
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Rocephin: Uses
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Perioperative Prophylaxis Lyme's Disease Osteomyelitis Gonoccol infections Bateremia/Septicemia
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Rocephin: Side Effects
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Headache Diarrhea Rash Phlebitis Thrombophlebitis
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Rocephin: Contraindications
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Hypersensitivity to other cephalosporins and PCN
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Rocephin: Drug Interactions
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Probenecid Aminoglycosides
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Rocephin: Nursing Considerations
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C&S before 1st dose Stable for 24 hrs @ room temp Used in home therapy Monitor IV site
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Ancef/Kefzol: Contraindications
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Hypersensitivity to other cephalosporins and PCN
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Ancef/Kefzol: Drug Interactions
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Probenecid
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imipenem/cisastatin NA
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Primaxin
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imipenem/cilastatin NA/Primaxin: Classification
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Miscillaneous Anti-infective
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Primaxin: Dosage & Frequency
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250MG-1GM IV 6-8 hrs over 30-60 minutes
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Primaxin: Uses
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Lower Respiratory Infections Urinary Tract Infections Bacterial Septicemia Intra-abdominal infections GYN infections
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Primaxin: Side Effects
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Pseudo membranous colitis Diarrhea Seizures Nausea Rash Phlebitis @ IV site
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Primaxin: Contraindications
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Hypersensitivity to drug
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Primaxin: Drug Interactions
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Aminoglycosides Probenecid Ganciclovir
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Primaxin: Nursing Considerations
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Caution in pts with PCN allergy, cephalosporin allergy and seizure disorders C&S before 1st dose Monitor IV site
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ertapenem sodium
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Invanz
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ertapenem sodium/Invanz: Classifacation
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Anti-bacterial
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Invanz: Dosage & Frequency
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1 GM IV once a day infused over 45-60 minutes
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Invanz: Uses
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Prophylaxis of surgical site infection following colorectal surgery Intra-abdominal infections
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Invanz: Side Effects
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Pseudo membranous colitis Diarrhea Phlebitis Nausea
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Invanz: Contraindications
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Hypersensitivity to Beta-lactams
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Ivanz:Nursing Considerations
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Stable for 6 hrs @ room temp 24 hrs refrigerated Monitor IV site
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vancomycin hydrochloride
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Vancocin
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vancomycin hydrochloride/Vancocin: Classification
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Miscillaneous Anti-infective
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Vancocin: Dosage & Frequency
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1-1.5 GMS IV Q 12 hrs administered slowly over 60-120 min depending on dose
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Vancocin: Uses
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#1 choice for treatment of MRSA Severe Systemic Infections Endocarditis Prophylaxis before dental procedures
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Vancocin: Side Effects
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"Red Man Syndrome" Ototoxicity Tinitus Nausea Pseudo membranous colitis Thrombophlebitis @ IV site
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Vancocin: Contraindications
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Pts allergic to drug
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Vancocin: Drug Interactions
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Aminoglycocides amphtericin B Cisplatin & pentamidine *All increase risk of nephrotoxity and ototoxicity
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Vancocin: Nursing Considerations
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C&S before 1st dose Evaluate hearing & renal status before administering Monitor site for irritation & phlebitis Change site frequently
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levofloxacin
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Levaquin
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levofloxacin/Levaquin: Classification
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Fluoroquinolones
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Levaquin: Dosage & Frequency
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250-500 MG IV daily infused slowly over 60 min
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Levaquin: Uses
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Bacterial Infections Chronic Sinusitis Chronic Bronchitis Nosocomial Pneumonia
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Lavaquin: Side Effects
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Seizures Rash Nausea Diarrhea Pseudo membranous colitis Photosensitivity Phebitis @ IV site
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Levaquin: Contraindications
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Hypersensitivity to drug or other fluoroquinolones
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Levaquin: Drug Interactions
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Antidiabetic agents (may alter blood glucose level) NSAIDS (may increase CNS stimulation) Coumadin (increase effect-monitor PT INR)
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Levaquin: Nursing Considerations
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C&S before 1st dose Limit sun exposure/Use sunblock Diabetics monitor glucose levels Watch blood glucose, renal & hepatic lab values-report any deviations to physician Monitor IV site
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metronidazole
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Flagyl
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metronidazole/Flagyl: Classification
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Amebicide
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Flagyl: Dosage & Frequency
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Loading dose for adult is 15mg/kg IV infused over 1hr. (750mg-1000mg) Can be given 1-2 times daily
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Flagyl: Uses
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Bacterial infections caused by anaerobic MO Prevention of infection in contaminated colorectal surgery
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Flagyl: Side Effects
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Headache Seizures N/V Diarrhea Vaginitis Dark urine (red-brown) Metallic taste in mouth Furry tongue Phlebitis @ IV site
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Flagyl: Contraindications
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Hypersensitivity to drug or other nitroimidazoles During 1st trimester of pregnancy
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Flagyl: Drug Interactions
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Disulfiram: acute psychoses and confusional state Lithium:increase levels can cause toxicity Coumadin: increased anticoagulant effect
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Flagyl: Nursing Considerations
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Pt must avoid alcohol Make pt aware of urine color changes Use hard candy for metallic taste in mouth Monitor I&O-stools Monitor IV site
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piperacillin sodium tazobactam sodium
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Zosyn
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piperacillin sodium/tazobactam sodium/Zosyn: Classification
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Extended Spectrum Penicillin
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Zosyn: Dosage & Frequency
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3.375 GM IV every 4-6 hrs infused over 30-45 min Adjust dose in renal impaired pt according to creatinine clearance (MD and Parmacist)
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Zosyn: Uses
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Rupture/abscess of appendix Peritonitis Post-Partum endometriosis or PID Nosocomial pneumonia
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Zosyn: Side Effects
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Headache Insomnia Nausea Diarrhea Rash-pruitis Hypertension Tachycardia Dyspnea
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Zosyn: Contraindications
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Hypersensitivity to drug or other pcn's
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Zosyn: Drug Interactions
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Oral anticoagulants-prolonged effect Oral contraceptives- decreased effect
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Zosyn: Nursing Considerationsf
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Check compatibility with other fluids/meds before admin C&S before 1st dose Monitor IV site Monitor Cystic Fibrosis pts closely for side effects