General Anesthesia for C-section – Flashcards

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question
How should all pregnant women be treated during intubation?
answer
treated as "full stomach"
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Why is a pregnant pt more susceptible to regug into esophagus?
answer
incompetent lower esophageal sphincter
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What are 3 meds you should give for aspiration prophylaxis before GA?
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1) reglan 2) Non-particulate antacid (bicitra) 3) H2 blocker (ranitidine)
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What are 2 ways reglan helps dec aspiration risks?
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1) inc gastric motility 2) inc lower esophageal sphincter tone
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How should reglan be administered? Why?
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SLOWLY (pushing too fast can cause temporary psychosis)
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What effect might reglan have on NMB?
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inhibits psuedocholinesterase
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What should you have pt do after taking bicitra?
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reposition (so it moves around in stomach)
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How long does bicitra work?
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1 HOUR! (may need to re-dose if C-section doesn't happen right away)
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Why should you give an H2 blocker before a C-section when it takes a while to work?
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can have prevent aspiration at end of case
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What is the avg blood loss for C-section?
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~1L
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Generally, blood loss has to be >_________L to affect mom's vital signs.
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>1.5L
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Rank the 6 risk factors for greater than avg blood loss from highest to lowest risk?
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1) general anesthesia 2) amnionitis 3) preeclampsia 4) prolonged active phase of labor 5) 2nd stage arrest (same thing as prolonged active labor) 6) Hispanic ethnicity
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General anesthesia has _____X more risk of greater than avg blood loss than regional anesthesia.
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3X
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Why does a mom w/ prolonged active phase of labor have inc risk of blood loss?
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uterus has tired out and has less forceful contractions to prevent blood loss
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What is the incidence of failed intubation in pregnant women?
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1:250
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What are 4 ways to overcome the obstacle presented by large breasts during DL?
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1) have circulator hold breasts out of the way 2) use a laryngoscope handle that is shorter (1-celled handle) 3) rotate 90 degrees to keep from hitting chest 4) take blade off and insert it like a tongue blade, then reattach the handle
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What should you do to all pregnant pts before intubation to maximize visualization?
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ramp them up! (place roll either perpendicular under shoulder or paralled under spine)
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What are the 3 pt populations most at risk for recall?
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1) emergency C-section 2) trauma 3) cardiac
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How should you adjust your dose of induction meds for a pregnant pt?
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use same dose
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What is a good combo of drugs for induction in pregnant population?
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propofol and small dose of ketamine (balance out side effects)
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What is the dose of ketamine recommended when used with propofol for induction?
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50mg
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What is the dose of ketamine recommended when given alone for induction?
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1mg/kg
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What is an alternate induction drug that can (but isn't often) used for induction?
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etomidate (0.3mg/kg)
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What is the recommended way to preoxygenate/denitrogenate you pt before C-section? Why is this important?
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-give 2-3 vital capacity breaths w/ tight fitting mask of 100% FiO2 (faster than waiting 5 min of normal breaths with loose fitting mask) -important bc they have smaller FRC and inc O2 demand --> faster desat during intubation
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What is the #1 cause of mortality in OB anesthesia?
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airway problems during general anesthesia
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How does the timing of induction vary btwn pts undergoing C-section vs. other general surgeries?
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-in other surgeries, you induce GA, then position and prep pt, then wait (can be 30+ minutes btwn induction and incision) -in C-section, you position and prep first, then wait until right before skin incision to induce
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What are 2 specific times you need to be sure to document during EVERY C-section?
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1) uterine incision-to-delivery time 2) time of umbilical cord clamping
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What is 1 time you need to be sure to document during C-sections under GENERAL anesthesia?
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induction-to-delivery time
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Studies show that as long as the induction-to-delivery interval lasts <_________minutes, you are not likely to cause clinically significant neonatal depression in a healthy fetus.
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<10minutes
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Due to historical thought and "habit", we still continue to have induction-to-delivery intervals of about _______ minutes. What is the only POSSIBLE disadvantage to this and how can you prevent this risk?
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2minutes -only possible disadvantage=MAYBE inc risk of recall for mom (can dec this risk by adding 50mg ketamine to propofol for induction)
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What is the NMB of choice for all general anesthesia C-sections unless there is a specific reason not to use it?
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succinylcholine
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What are 2 reasons that Succ is the NMB of choice for GA C-sections?
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1) aspiration risk 2) risk for difficult airway/failed intubation
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Should you or should you not give a defasiculating dose of NMB during GA C-sections? Why?
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should NOT; if you give a defasiculating dose of nondepol NMB, then you have to give 1.5mg/kg of succ (instead of 1mg/kg) which increases the duration of succ --> prob for risk of failed intubation
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Approx how long after a 1mg/kg dose of Succ can the pt be "rescued" back to breathing after failed intubation?
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7-8 min
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Approx how long after 1.5mg/kg (defasiculating) dose of Succ can the pt be "rescued" back to breathing after failed intubation?
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10-15 min
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Approx how long after 0.3-0.4mg/kg (ED95) dose of Succ can the pt be "rescued" back to breathing after failed intubation?
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4-5 min
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What is one disadvantage to using a smaller (0.3-0.4mg/kg) dose of Succ for intubation?
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gives you a much smaller window of opportunity where cords are open for intubation (want to DL and then wait for cords to open, then pass the tube)
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What are 3 situations that (especially when seen together) can greatly prolong the duration of Succ?
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1) dec pseudocholinesterase in pregnancy 2) metoclopramine dec pseudocholinesterase 3) mag sulfate dec pseudocholinesterase (BIGGEST factor)
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What should you ALWAYS do after using Succ for induction before you either redoes NMB or extubate the pt?
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check for recovery of twitches
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In what 5 situations would you possibly choose to use a non-depolarizing NMB for induction?
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1) Risk of MH (most likely reason) 2) pseudocholinesterase deficiency 3) burn pt 4) spinal cord injury (depending on time frame) 5) muscular dystrophy
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What is the FIRST thing you should do after you induce general anesthesia and you then realize you can't intubate?
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call for help
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You should never try laryngoscopy more than _______ times before moving down the airway algorithm.
answer
2
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What is the next step (after calling for help) that you should do after you induce GA and realize you can't intubate?
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mask ventilate (face mask OR LMA) while maintaining cricoid pressure
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If you choose to place an LMA after failed intubation, what type of LMA should you use?
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one you can intubate through (and place the ETT as soon as possible)
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If you choose to face mask ventilate after failed intubation, what else should you do?
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place an oral airway
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Is the main reason you might not be able to ventilate well with an LMA after failed intubation?
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inability to place LMA correctly d/t cricoid pressure (may need to let up cricoid pressure JUST long enough to insert LMA)
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What are 4 reasons you might not be able to ventilate well with a face mask after failed intubation? Which reason is most likely and how can you handle it?
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1) no good seal (may need to use 2 hands) 2) laryngospasm/bronchospasm (unlikely) 3) airway collapsing d/t upper airway swelling (treat w/ PEEP) 4) cricoid pressure might have collapsed airway (most likely--> treat by having person applying cricoid pressure slowly let up while you ventilate and as soon as you are able to ventilate, keep cricoid pressure at that level)
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But doesn't letting up on cricoid pressure increase aspiration risk??? Why is it ok to do this during face mask ventilation?
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risk of no ventilation is MUCH greater and more serious than risk of aspiration
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What is the next step on the algorithm if mask ventilation is NOT adequate after failed intubation?
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go to ASA difficult airway algorithm (emergency pathway)
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What is the next step on the algorithm if you ARE able to provide adequate mask ventilation, either with an LMA or face mask?
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determine if there is fetal distress
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If you ARE able to mask ventilate and determine that the fetus IS in distress, what are your 3 choices? Which is most often chosen?
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1) wake mom up and perform safe intubation 2) surgical airway 3) continue case w/ cricoid pressure and get baby out fast! (most often chosen)
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What is the risk associated with waking mom up and performing safe intubation (awake FO, etc)?
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possible fetal demise
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What is the risk associated with continuing case w/ cricoid pressure and delivering baby ASAP?
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aspiration (still better risk than immediate mother and/or fetal demise); once baby is out, you have more options for airway mgmt
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What are 2 choices for surgical airway if mask ventilation is not adequate? What might be necessary to do in the mean time until surgical airway can be inserted?
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cricothyrotomy or tracheostomy (may need manual jet ventilation until trach can be placed)
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What are 2 important things to remember when inserting a catheter in the cricothyroid membrane for jet ventilation?
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1) aspirate for air to confirm placement in trachea 2) point needle caudad to avoid hitting vocal cords
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If mask ventilation IS adequate and there is NO fetal distress, what is the best next step?
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wake mom up and start process over with new plan (awake FO or call in the "airway pro" to try again)
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What is the goal for uterine incision-to-delivery time in all C-section cases (not just under GA)?
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< 3 min
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What happens at the time the last (if multiple babies) cord is clamped?
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Pitocin drip is started
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What are 3 s/s of Pitocin overdose?
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1) vasodilation 2) hTN 3) skin flushing
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What is the t1/2 of Pitocin in term pregnant women?
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5-15min (requires infusion for prolonged affect)
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What are 2 alternatives to Pitocin to stimulate uterine contractions?
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1) ergot alkaloid (IM injection) 2) prostaglandin
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What are 2 drug classes that should be avoided before cord is clamped?
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opioids or benzos (fetal depression)
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After induction (with propofol and/or ketamine), what are 3 options to keep the pt asleep before delivery of baby?
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1) propofol drip (not used often) 2) volatiles 3) N2O
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What cntn of volatiles is recommended for use UNTIL delivery of baby?
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< 2/3 MAC (b/c MAC is dec in pregnancy, 2/3 MAC is almost equivalent to 1MAC in a nonpregnant pt)
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What is the only reason you would need to d/c volatile agent after delivery of baby?
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if you are not able to achieve adequate uterine contraction w/ volatiles still on (if uterus does not IMMEDIATELY begin to contract when you turn Pitocin on, you should immediately turn volatile off)
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What are 5 options to add to opioid after delivery of baby to provide amnesia?
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1) N2O (very tricky when used alone w/ opioids) 2) ketamine 3) propofol drip 4) versed 5) IV scopolamine (not used often b/c wild on emergence)
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True or False: If twitches return after succ induction before surgery is completed, it is necessary to redose NMB to allow surgeon ability to close.
answer
False (empty abdomen b/c no mo babe will not be hard to close) only need to redose NMB if pt starts trying to leave (moving arms or legs)
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