question

Fatty acids are taken up by cells, where they may serve as precursors in the sythesis of other compounds

answer

as fuels for energy production, and as substrates for ketone body sythesis

question

Ketones bodies may be exported to other tissues where they can be used for

answer

energy production

question

Fats are an important source of dietary calories. Typically ___% of calories in the American diet are from fat.

answer

30-40

question

Fat is the major form of energy storage. In a typical individual the fuel reserves are distributed as follows:

answer

fat: 100,000 kcal

protein: 25,000 kcal

carbohydrate: 650 kcal

question

Fatty acids are intermediates in the sythesis of other important compounds. Examples include:

answer

phospholipids (in membranes), Eicosanoids, including prostaglandins and leucotrienes, which play a role in physiological regulation

Unlock the answer

question

Some diseases involve disturbances in fatty acid metabolism. These include:

answer

diabetes mellitus, specific disorders of fatty acid oxidation, such as Sudden Infant Death Syndrome and Reye Syndrome, which might be related to a deficiency of medium chain acyl CoA dehydrogenase, an important enzyme of fatty acid oxidation

Unlock the answer

question

Here are the major metabolic sources of acetyl CoA and some of the pathways for which it serves as a substrate

answer

[image]

Unlock the answer

question

Acetyl CoA is at the center of lipid metabolism. It is produced from:

answer

Fatty acids, glucose (through pyruvate), Amino acids, Ketone bodies

Unlock the answer

question

Acetyl CoA can be converted to fatty acids, which in turn give rise to:

answer

triglycerides, phospholipids, eicosanoids, ketone bodies

Unlock the answer

question

Acetyl CoA is the precursor of cholesterol, which can be converted to:

answer

steroid hormones, bile acids

Unlock the answer

question

Acetyl Co Metabolism produces energy, generated by the complete oxidation of acetyl CoA to

answer

carbon dioxide and water through the tricarboxlic acid cycle and oxidative phosphorylation.

Unlock the answer

question

The structure of Acetyl CoA consists of two parts:

answer

Acetyl group and Coenzyme A

Unlock the answer

question

Coenzyme A:

answer

Beta-mercaptoethylamine, Pantothenic acid (not synthesized in man - an essential nutrient), phosphate, 3',5'-adenosine diphosphate

Unlock the answer

question

Function of CoA

answer

CoA is a commonly used carrier for activated acyl groups (acetyl, fatty acyl and others). The thioester bond which links the acyl group to CoA has a large negative standard free energy of hydrolysis (-7.5kcal/mole). This qualifies it as a high energy bond, and explains why an acyl group attached to CoA in this manner is considered to be activated.

Unlock the answer

Fatty Acid Synthesis Answers – Flashcards

Unlock all answers in this set

Haven't found what you were looking for?

Search for samples, answers to your questions and flashcards