Epidemiology – Respiratory Disease (Diphtheria-Common cold – Flashcards
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            What is Diphtheria
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        is acute bacterial disease involving the tonsils, pharynx, larynx and nose
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            Which are the signs and symptoms for Diphtheria
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        • marked by patches of an adherent grayish membrane with a surrounding inflammation  • sore throat  • enlarged tender cervical lymph nodes  • edema in the neck
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            Which are infectious agent of Diphtheria
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        Corynebacterium diphtheriae
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            How is the presumptive diagnosis done for Diphtheria
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        Is based on observation of a whitish membrane extending to the uvula and soft plate
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            With what is associate the presumptive diagnosis of Diphtheria
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        Tonsilitis   Pharyngitis   Cervical lymphadenopathy  Serosanguinous nasal exchange
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            How is the confirmatory diagnosis done for Diphtheria
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        by bacteriologic examination of lesions
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            Which is the treatment for Diphtheria
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        Antitoxin of equine origin given immediately after bacteriologic specimens are taken a single dose of 20,000-100,000 units IM
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            Which is the treatment for severe infection of Diphtheria
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        Is given IV and IM E-mycin or PCN are effective administer after cultures are obtained in conjunction with antitoxin
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            Which is the treatment that is recommended when patient can't swallow
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        Procaine PCN G (IM)
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            Which is the occurrence for Diphtheria
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        Colder months in temperate zones primarily involving non immunized children less than 15 yrs of age   Adults whose immunization has been neglected
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            Which is the mode of transmission for Diphtheria
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        Contact with patient and carrier   Contact with infected formites with d/c from lesions  Milk can serve as a vehicle
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            Which is the incubation period for Diphtheria
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        Usually 2-5 days ; occasionally longer
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            Which is the period of communicability for Diphtheria
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        Usually 2 weeks or less  Seldom more than 4 wks   Effective antibiotic therapy promptly terminates shedding   Chronic carrier shed for 6 months or more
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            Which is the susceptibilty and resistance for Diphtheria
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        Infants: passive usually lost in 6 mionths   Immunity: active induced by toxoid
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            Which are the preventive measures for Diphtheria
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        Education and Active Immunization
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            Which are the control of patient measures for Diphtheria
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        Report to HD  Isolation   Disinfection of soiled articles   Quarantine   Management/Investigation of contacts ( use of PCN and E-mycin as chemoprophylaxis)  Treatment
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            How is Rubella (German Measles) chararcterized
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        Is an mild febrile viral disease that is characterized as a diffuse punctate and maculopapular rash somtimes resembling that of measles or scarlet fever
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            Which is the prodromal stage that adults may experience
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        Is a 1-5 days prodrome of   Low grade fever  Headache   Malaise  Mild coryza  conjuntivitis
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            Which is the most characteristic clinical feature for Rubella
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        Is a postauricular, occipital and posterior cervical lymphadenopathy that precedes the rash by 5-10 days
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            What is common in Rubella and Rubeola
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        Leukopenia
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            How is the diagnosis done for Rubella
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        Lab confirmation by fourfold rise in specific antibody titer by ELISA
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            Which is the occurrence of Rubella
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        Is prevalent in winter and spring  Is primarily a disease of childhood in non immunized poblation
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            Which is the mode of transmission of Rubella
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        Contact with nasopharyngeal secretions  Droplet spread or direct contact  Infants can shed large quantities of virus in their pharygeal secretions and urine
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            Which is the incubation period of Rubella
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        Range 14-21 days with average of 14-17 days
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            Which is the period of communicability of Rubella
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        High communicable 1 wk before and at least 4 days after onset of rash   Infants shed virus for months after birth
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            What is Rubeola (Measles)
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        Is an acute highly communicable viral disease with prodromal fever  conjuntivitis   coryza  cough   koplik spots on the buccal mucosa
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            What does appear on the 3rd to 7th day of Rubeola infection
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        Appear a characteristic red blothchy rash that begins on the face becomes generalized and last 4-7 days
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            Which are the complications of Rubeola
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        Otitis media  Pneumonia  Laryngotracheobronchitis (croup)  diarrhea  encephalitis
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            How is the diagnosis done for Rubeola
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        Made clinical and epidemiological grounds   confirm by the detection of measles specific IgM antibiodies  viral antigen using FA techniques   virus isolation in cell cuture from blood, conjuntiva, nasopharynx or urine taken the 3rd day of rash
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            Which is the occurence of Rubeola
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        Is one of the most highly communicable ID and a herd immunity of > 94% may be needed to interrupt transmission
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            Which is the mode of transmission for Rubeola
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        Airborne by droplet  Direct contact with nasal or throat secretion  Contact with infected formites with nose and throat secretions
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            Which is the incubation period of Rubeola
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        About 10 days  It can vary from 7-18 days from exposure to onset of fever  Usually 14 days until rash appears
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            Which is the period of communicability of Rubeola
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        before the begining of the prodromal period to 4 days after appearance of the rash minimal after the second day
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            Which is the susceptibility and resistance of Rubeola
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        Maternal antibody interfieres with response to vaccine: Immunization at 15 months produced immunity in 95-98% and re-immunization may increase immunity levels to as high as 99%
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            How is Pneumococcal Pneumonia characterized
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        Is an acute bacterial infection typically characterized by a sudden onset of shaking chills, fever, pleural pain, dyspnea, tahypnea, productive cough of "rusty" sputum and leukocytosis
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            Which is the initial manifestation of Pneumococcal Pneumonia
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        Fever, vomiting and convulsions is tne initial manifestation in infants and young children
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            Which is the infectious agent for Pneumococcal Pneumonia
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        Streptococcus pneumoniae
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            How is the suspected diagnosis done for Pneumococcal Pneumonia
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        Presence in gram stains of sputum
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            How is the confirmed diagnosis done for Pneumococcal Pneumonia
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        By isolation of pneumococci from secretions from the lower respiratory tract of adults
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            Which is the treatment of Pneumococcal Pneumonia
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        PCN G (preffered)  E-mycin ( hypersensitve to PCN)  Vancomycin and Chloramphenicol (Multiresistant strains)
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            Which is the occurrence of Pneumococcal Pneumonia
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        Lower socioeconimic groups and developing countries   Highest in winter and spring
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            Which is the reservoir for Pneumococcal Pneumonia
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        Commonly found in the upper respiratory tract of healthly people throughout the world
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            Which is the mode of transmission for Pneumococcal Pneumonia
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        Droplet   Direct oral contact  Indirectly through contaminated formites with respiratory d/c
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            Which is the incubation period for Pneumococcal Pneumonia
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        Short as 1-3 days
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            Which is the susceptibility and resistance of Pneumococcal Pneumonia
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        Risk of infection is increased by   influenza  pulmonary edema  aspiration following alcoholic intoxication   chronic lung disease  age
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            Which is the preventive measure for Pneumococcal Pneumonia
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        avoid crowding in living quarters  administration of vaccine to high risk person
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            Which is the control of patient measures for Pneumococcal Pneumonia
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        Report to HD  Isolation  treatment
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            What is Legionellosis
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        Is an acute bacterial disease with 2 currently recognized, distinct clinical and epidemic manifestation
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            Which are the 2 distinct clinical and epidemic manifestation of Legionellosis
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        Legionnaire's disease  Pontiac fever
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            How are both manifestation of Legionellosis characterized
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        Both are characterized initially by   anorexia   malaise  myalgia  headache  Within a day:  fever associated with chills temperatures reach 39°C-40.5° C (102°F-105°F)
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            Which is common in both manifestation of Legionellosis
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        nonproductive cough, abdominal pain and diarrhea
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            What is shown on the x-ray for Legionnaire's disease
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        It show patchy or focal areas of consolidation tha tmay progress to bilateral involvement and ultimately to respiratory failure
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            In how many days does the patient recover without treatment of Legionellosis
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        2-5 days
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            Which is the infectious agent for Legionellosis
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        Legionellae pneumophila
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            How is ths diagnosis done for Legionellosis
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        Detection of antigens of Legionellae pneumophilain urine by RIA or by a fourfold or greater rise in IFA titer
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            Which is the treatment of Legionellosis
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        E-mycin
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            Which is the occurrence of Legionellosis
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        Throughout North America as well as in Australia, Africa, South America and Europe
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            When are sporadic cases and outbreaks of Legionellosis recognized
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        They are recognized more commonly in summer and autumn
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            Which is the reservoir for Legionellosis
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        It is primarily aqueous  Hot water systems  Air conditioning cooling towers  evaporative condensers  humidifiers  whirlpool spas  respiratory therapy devices  decorative fountains   hot and cold water taps and showers  hot tubs  creeks and ponds and the soil from their banks
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            Which is the mode of transmission of Legionellosis
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        Epidemiologic evidence supports airborne transmission
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            Which is the incubation period of Legionellosis
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        Range 2-10 days average 5-6 days
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            Which is the susceptibility and resistance of Legionellosis
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        Illness occurs most frequent with increasing age   Outbreaks have occurred in hospitalized patients
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            Which are the preventive measures of Legionellosis
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        Cooling towers drained and cleaned periodically and when not in use   Avoid tap water in respiratory devices   maintain hot water system more or equal to 122°F
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            Which is the cotrol of patient for Legionellosis
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        Report of HD  Investigate contacts and source
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            What is the Common Cold
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        An acute catarrheal infection of the upper respiratory tract
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            How long does Common Cold last and characterize by
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        It last 2-7 days characterized by   coryza  sneezing   lacrimation   irritated nasopharynx  chilliness  malaise
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            What is uncommon with Common Cold
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        Fever is uncommon in children over
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            What can accompany the Common Cold
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        laryngitis  tracheitis   bronchitis
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            What serious complication can Common Cold predispose
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        Sinusitis  Otitis media
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            Which are the infectious agents for Common cold
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        Rhinoviruses ( major known )  Coronaviruses (10-15%  Influenza
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            Which are the infants infectious agents for Common Cold
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        Parainfluenzavirus  RSV  Influenza virus  Adenovirus
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            Which is the occurrence for Common cold
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        In template zonas, incidence rises in fall, winter and spring   In tropical setting, incidence is highest in the rainy season  Incidence is highest in children under 5 yrs and gradually declines with increasing age
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            Which is the mode of transmission of Common cold
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        Direct contact  Inhalation of airborne droplets
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            Which is the incubation period of Common cold
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        12hrs to 5 days usually 48hrs
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            Which is the period of communicability of the Common cold
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        Nasal washing taken 24 hrs before onset and for 5days after onset
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            Which is the preventive measures of Common cold
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        educate public in personal hygiene   avoid crowed living space  immunize with oral live adenovirus
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            Which is the control of patient measures of Common cold
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        report to HD  Isolation  disinfection of soiled articles   investigation of contacts