Docusate Sodium (generic)/ Colace (brand name)

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classification (therapeutic)
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laxatives
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classification (pharmacologic)
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stool softeners
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indications
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PO: prevention of constipation (in pts who should avoid straining, such as after MI or rectal surgery)
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action
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Promotes incorporation of water into stool, resulting in a softer fecal mass. May also promote electrolyte and water secretion into the colon. Therapeutic Effects: Softening and passage of stool.
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contraindications/ precautions
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contraindicated in: hypersensitivity; abdominal pain; nausea or vomiting; use cautiously in: excessive or prologued use may lead to dependence, should not be used if prompt results are desired
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adverse reactions/ side effects
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EENT: throat irritation. GI: mild cramps; Derm: rashes
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interactions
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drug-drug: none significant
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Dosage
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50-400mg in 1-4 divided doses
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nursing implications
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ASSESSMENT: assess for abdominal distention, presence of bowel sounds, and usual pattern of bowel function; assess color, consistency, and amount of stool produced; LAB CONSIDERATIONS: N/A ; TOXICITY AND OVERDOSE: N/A, POTENTIAL NURSING DIAGNOSES: Constipation (Indications) IMPLEMENTATION: PO: administer with a full glass of water or juice, may be administered on an empty stomach for more rapid results; Oral solution may be diluted in milk or fruit juice to decrease bitter taste; Do not administer within 2 hour of other laxatives, especially mineral oil. May cause increased absorption. PT/FAMILY TEACHING: advise pt of short term use of the laxatives; long term may cause electrolyte imbalance and dependency; encourage pt to use other form of bowel regulation, such as increasing bulk and water in the diet; Instruct pts with cardiac disease to avoid straining during bowel movements (Valsalva meneuver); advise pt not to use laxatives when abdominal pain, nausea, vomiting, or fever is present; advice pt not to take docusate within 2hr of other laxatives EVALUATION/ DESIRED OUTCOME: A soft formed bowel movement, usually within 24-48 hr. Therapy may take 3-5 days for results. Rectal dose forms produce results within 2-15 min.

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