Chapter Review 14 – Flashcards

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Define pathogenesis.
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__________, the manner in which a disease develops.
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Define Pathology.
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_________ is the scientific study of diseases
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Define Etiology.
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Pathology is first concerned with the cause, or ________, of diseases.
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Define Infection
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_________ is the invasion or colonization of the body by pathogenic microorganisms.
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Define Diseases.
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_______ occurs when an infection results in any change from a state of health.
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Define Transient Microbiota.

Example:
Skin - Staphylococcus
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_________ _________ are microorganisms that are present in an animal for a short time without causing a disease.

 

 

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Define Normal Microbiota.

Example:
Large Intestine: Escherichia coli
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The microorganisms that establish more or less permanent residence (colonize) but that do not produce disease under normal conditions are members of the body's ______ ________.
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Define parasitism.

Example:
Helminths or Parasitic Worm.
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One organism benefits by deriving nutrients at the expense of the other; this relationship is called __________.
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Define Opportunistic Pathogens.
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_____________ __________ ordinarily do not cause disease in their normal habitat in a healthy person but may do so in a different environment.
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Define Pathogen
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A _______ is an agent that causes disease, especially a living microorganism such as a bacterium, virus, or fungus.
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How do opportunistic pathogens differ from pathogens?
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True Pathogen - are capable of causing disease in healthy persons with normal immune defenses. ex. influenza virus, plague bacillus, and ect.


Opportunistic pathogen - cause disease when the host's defenses are compromised or when they grow in part of the body that is not natural to them.

 

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List Koch’s postulates in the order in which his experiments applied the postulates.
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  1. The same pathogen must be present in every case of the disease
  2. The pathogen must be isolated from the diseased host and grown in pure culture.
  3. The pathogen from the pure culture must cause the disease when it is inoculated into a healthy, suscptible laboratory animal.
  4. The pathogen must be isolated from the inoculated animal and must be shown to be the orginal organism.

 

 

 

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What is the main goal of Koch’s postulates (give an example)? What are the exceptions?
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A specific infectious disease is associated with a specific microbe.

 

Exceptions - Some infectious diseases can be caused by several different pathogens, all of which causing the same signs and symptoms. Others cause several disease conditions.

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Define Symptoms.
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The patient may experience certain ________, or changes in body function, such as pain and malaise (a vague feeling of body discomfort).
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Define signs.
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The patient can also exhibit _____, which are objective changes that the physician can observe and measure.
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Define syndrome.
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A specific group of symptoms or signs may always accompany a particular disease; such a group is called a  ________.
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Define Communicable Disease.
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Any disease that spreads from one host to another, either directly or indirectly, is said to be a __________ ______.

 

Example: Chickenpox, measles, genital herpes, typhoid fever, and tuberculosis.

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Define Noncommunicable Diseases.
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_______________ _____ is not spread from one host to another.

 

Example: Skin Cancer, Diabetes Type 2

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Define Contagious Disease.
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__________ _______ is a disease that is easily spread from one person to another.

 

Example: Chickenpos and Measles.

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Define Incidence.
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The ________ of a disease is the number of people in a population who develop a disease during a particular time period.

 

ie: The ________ of AIDS in the US in 2007 was 56,300 vs 1,185,000 cases up to that point.

 

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Define Prevalence.
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The _______ of a disease is the number of people in a population who develop a disease at a specified time, regardless of when it first appeared.

 

Taking into account both old and new cases.

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Define Sporadic Disease.
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A _______ _____ is a particular disease tha only occurs occasionally.

 

ie: typhoid fever

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Define Endemic Disease.
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A disease constantly present in a population is called an _____ _____.

 

ie: common cold, malaria, colora

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Define Epidemic Disease.
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If many people in a given area acquire a certain disease in a relatively short period, it is called a/an ________ _______.

 

ie: influenza, AIDS

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Define Pandemic Disease.
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An epidemic disease that occurs worldwide is called a _______ ______.

 

ie: influenza, AIDs

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Define Herd Immunity.
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____ _______ is when many immune people are present in a community.

 

ie: Chickenpox, Measles

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Define Acute Disease.
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An _____ ______ is one that develops rapidly but last only a short time.

 

ie: influenza

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Define Chronic Disease.
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A ______ _____ develops more slowly, and the body's reactions may be less sever, but the disease is likely to continue or recur for long periods.

 

ie: Hepatitis B, tuberculosis, and infectious mononucleosis

 

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Define Latent Disease.
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A ______ ______ is one in which the causative agent remains inactive for a time but then becomes active to produce symptoms of the disease;

 

ie: shingles, one of the disease caused by varicella virus.

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Define Local infection.
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A _____ ______ is one in which the invading microorganisms are limited to a relatively small area of the body.

 

ie: boils, abscesses, acne

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Define Systemic infection.
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In a ______ ______, microorganisms or their products are spread throughout the body by the blood or lymph.

 

ie: Measles, septicemia

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Define Bacteremia.
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The presence of bacteria in the blood is known as __________.
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Define Toxemia.
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The presence of toxins in the blood is called _______.

 

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Define Viremia.
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_______ refers to the presence of viruses in the blood.
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Define Septicemia.
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_________, also called blood poisoning, is a systemic infection arising from the multiplication of pathogens in the blood.
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Define primary infection.
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______ ______ is an accute infection that causes the initial illness.

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Define Secondary Infection.
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A _________ _________ is one caused by an opportunistic pathogen after the primary infection has weakened the body's defenses.
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Name the stages of a disease. (6)
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  1. Incubation Period
  2. Prodromal Period
  3. Period of Illness
  4. Peck of Illness
  5. Period of Decline
  6. Period of Convalescence

 

 

 

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Define Incubation Period.
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The ________ _____ is the interval between the initial infection and the first appearance of any signs or symptoms. Patient is highly contagious.

 

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Define Prodromal Period.
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The _________ ______ is a relatively short period that follows the period of incubation when the first symptoms of illness appear. Patient shows mild symptoms of the disease, such as general aches and malaise.
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Define Period Of Illness.
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During this period the disease is most severe. Patient shows the most severe signs and symptoms and white blood cells may increase or decrease. Patient is also contagious.

 

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Define Period of Decline.
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During this period the signs and symptoms subside but the patient is vulnerable to secondary infections.
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Define Period of Convalescence.
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The recovery period or ______ __ __________, is when the body returns to its prediseased state. Patient becomes a chronic reservior and is the most contagious.

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Define Peck of Illness.
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The ___ __ _____ is when the pathogen dies or our immune system wins.
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Define Predisposing factor.
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This makes the body more suceptible to a disease and may alter the course of the disease.
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Give A Few Examples of Predisposing Factors.
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Gender - Females have a higher incidence of urinary track infections than males

Genes - Sickle Cell disease is a severe, life-threatening form of anemia that occurs when the genes for the disease are inherited from both parents.

Climent and Weather - In temperate regions, the incidence of respiratory disease increases during the winter. Due to close contact indoors which spread respiratory pathogens.

Others - Nutrition, fatigue, age, environment, habits, lifestyle, occupation, preexisting illness, chemotherapy, and emotional disturbances.

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Define Reservoir of Infection.
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This is a continual source of infection.

 

ie: human, animal, or nonliving.

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Define Carriers and give an Example.
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These are people that harbor pathogens and transmit them to others without exhibiting any signs of illness. They are important living resevoirs of infection.

 

ie. incubation period, convalescent period, Typhoid Mary, AIDs

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Define Zoonoses.
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Diseases that occur primarily in wild and domestic animals and can be transmitted to humans are called ________.

 

ie. rabies (bats, skunks, foxes, dogs, coyotes), lyme disease (field mice)

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Give 2 major examples of Nonliving Reservoirs.
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1. Soil - harbors such pathogens as ringworm, Clostridium Botulinum (causing botulism), C. tetani (causing tetanus).

 

2. Water - Feces contaminate the water, causing gastrointestinal diseases. Vibrio cholerae, causing cholera, and Salmonella Typhi causing typhoid fever.

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(General) List the modes of transmission of disease. (3)
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1. Contact Transmission

2. Vehicle Transmission

3. Vector Transmission

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Define Contact Transmission.
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_______ ________ is the spread of an agent of disease by direct contact, indirect contact, or droplet transmission.

 

ie: Influenza, Rabies

 

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Define Direct Contact Transmission.
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Also knon as personn-to-person transmission, is the direct transmission of an agent by physical contact between its source and a susceptible host; no intermediate object is involved.

 

ie: touching, kissing, and sexual intercourse. Hep A, Influenza, staphylococcal.

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Define Indirect Contact Transmission.
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_______ _______ ____________ occurs when the agent of disease is transmitted from its reservoir to a susceptible host by means of a nonliving object.

 

ie; tissues, handkerchiefs, towels, bedding, diapers, drinking cups, eating utensils, toys, mone, etc..

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Define Droplet Transmission.
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Transmission in which microbes are spread in droplet nuclei (mucus droplets) that travel only short distances.

 

ie: coughing, sneezing, laughing, or talking and travel less than 1 meter from the reservoir to the host.Influenza, pneumonia, whooping cough.

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Define Vehicle Transmission. (3) And Give an Example of each.
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This is the transmission of disease agents by a medium, such as water, food, or air.


ie:

Water - water contaminated with untreated or poorly treated sewage. Cholera, waterborn shigellosis, and leptospirosis.

Food - incompletely cooked, poorly refrigerated, or prepared under unsanitary conditions. (food poisoning and tapeworm infestation)

Air - Travel more then 1 meter, Measles/Tuberculosis, dust particles (Staphylococci), Spores.

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Define Vectors and Give 3 Examples.
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Also known as Arthropods, are animals that carry pathogens from one host to another.

 

ie: yellow fever, dengue fever, plague, rocky mountain spotted fever, (table 14.3)

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Define Biological transmission
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Active process, arthropod gets infected, it reproduces in the vector then retransmitted.


Pass through feces, salivary glands

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Define Mechanical transmission.
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Passive transport of pathogens, insect body parts, (typhoid fever)

 

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Define Noscomial Infections and give 3 examples.
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A ______ ______ does not show any evidence of being present or incubating at the time of admission to a hospital; it is acquired as a result of a hospital stay. (antibody resistant)

 

ie; UTI, Surgical site infections, lower respiratory infections. (table 14.5)

 

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Define Emerging Infectious Disease and give 2 examples.
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_____ _____ _____ are ones that are new or changing, showing an increase in incidence in the recent past, or a potential to increase in the near future.

 

ie; HIV, West Nile virus, SARS (table 14.6)

 

 

 

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Define Nationally Notifiable Diseases and give 3 examples.
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__________ are any disease that is required by law to be reported to government authorities.

 

ie; HIV, anthrax, cholera, measles, lyme disease, (table 14.7)

 

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Define Epidemiology.
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The science that studies when and where diseases occur and how they are transmitted in populations is called ____________.
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(General) What are 3 types of Epidemiology?
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Descriptive Epidemoilogy

Analytical Epidemiology

Experimental Epidemiology

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