Chapter 20 Medical Terminology – Cancer – Flashcards
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Benign
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Slow growth, expansion, remains localized, well differentiated
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Malignant
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Rapid growth, infiltration, metastasis by bloodstream and lymphatics, poorly differentiated
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Polyp, papilloma
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Any benign tumor projecting from surface epithelium
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Root word + oma (suffix)
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A benign tumor; root word designates primary tissue of origin
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Carcinoma
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Malignant tumor arising from surface, glandular, or parenchymal epithelium (but not endothelium or mesothelium)
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Sarcoma
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Malignant tumor of any primary tissue other than surface, glandular, and parenchymal epithelium
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Leukemia
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Neoplasm of blood cells
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aden/o
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Gland
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angi/o
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Vessels (type not specified)
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chondr/o
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Cartilage
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fibr/o
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Fibrous tissue
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hemangi/o
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Blood vessels
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lymphangi/o
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Lymph vessels
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lip/o
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Fat
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my/o
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Muscle
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neur/o
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Nerve
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oste/o
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Bone
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Lymphoid tumors
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All neoplasms of lymphoid tissue are called lymphomas and are malginant: Hodgkin's disease and non-Hodgkin's lymphomas
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Skin tumors
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Pigment-producing cells of the epidermis
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Teratoma tumors (of mixed components)
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Derived from cells that have the potential to differentiate into different types of tissue (bone, muscle, glands, epithelium, brain tissue, hair) and may be either benign or malignant
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Embryonic tumors
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Derived from persisting groups of embryonic cells of the brain, retina, adrenal gland, kidney, liver, or genital tract; named from the site of origin, with the suffix "-blastoma" added
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Noninfiltrating (in situ) carcinoma
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Noninfiltrating tumors are common in many locations, including the breast, cervis, colon, skin, and urinary tract
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Precancerous conditions
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Refers to conditions that have a high likelihood of developing into cancer
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Aspirate
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Withdrawal of fluid from a lump, often a cyst
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Biopsy
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Removal of cells or tissues for examination under a microscope
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Scope
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A procedure in which a thin, lighted tube is inserted into the body part being examined and a tissue sample (biopsy) is taken to examine under a microscope to determine if cancer cells are present
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Bronchoscopy
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Scope inserted through the nose or mouth to examine the inside of the trachea, bronchi, and lung
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Colonoscopy
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Scope inserted into the rectum to examine the colon
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Cystoscopy
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Scope inserted into the urethra to examine the bladder
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Laryngoscopy
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Examination of the larynx (voice box) with a mirror (indirect laryngoscopy) or with a laryngoscope (direct laryngoscopy)
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Sigmoidoscopy
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Scope inserted into the sigmoid part of the colon; also called proctosigmoidoscopy
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Tumor markers
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Obtained from blood sample
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Acid phosphatase
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For cancer of the prostate
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AFP
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For hepatocellular carcinoma germ cell tumors
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CA 19-9
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For cancers of the pancreas, colon, cervix, and ovary
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CA 125
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For epithelial ovarian cancer
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CEA
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For cancers of the pancreas, colon, breast, lung, stomach, ovary
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HCG/AFP
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For malignant germ cell tumors originating from ovaries or sperm; ovarian or uterine cancer in women and testicular cancer in men
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Monoclonal immunoglobins
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For multiple myeloma
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PSA
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For cancer of the prostate
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Imaging
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X-ray or computerized view with or without a contrast dye or radioactive substance
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Barium enema
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For cancer of the colon
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Computed axial tomography (CAT, CT, ACTA)
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For cross-section images of internal structures
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Intravenous pyelogram or intravenous pyelography (IVP)
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For cancer of the kindeys, ureters, and bladder
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Lymphangiography
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For lymph node involvement, especially Hodgkin's disease, lymphoma, cancer of testes
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Radionuclide scan
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For showing function and size of specific organ (brain, bone, liver, spleen, kidney)
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Ultrasound
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For visualizing structural changes, mass (stomach, pancreas, kidney, uterus, ovary)
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Microscopic examination
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Obtained from a tissue sample
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Bone-marrow aspirate
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For tumor involvement, especially by leukemia or lymphoma
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Estrogen/progesterone receptors
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For cancer of the breast
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Pap smear
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For cancer of the cervix or uterus
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Sentinel lymph node biopsy
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For tumor metastasis, for example, breast cancer
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Sputum cytology
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Bronchogenic cancer
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Stool guaiac
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For cancer of the colon/rectum
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Biological
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Treatment to stimulate or restore the ability of the immune system to fight infection and disease
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Autologous bone marrow transplantation
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A procedure in which bone marrow is removed from a person, stored, and then given back to the person following intensive treatment
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BCG vaccine
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An anticancer drug, bacille calmette-Guerin, that activates the immune system
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Colony-stimulating factors
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Substances that stimulate the production of blood cells; granulocyte colony-stimulating factors (G-CSF); granulocyte-macrophage colony-stimulating factors (GM-CSF)
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Peripheral stem cell transplantation
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Replacing blood-forming cells destroyed by cancer treatment. Immature blood cells (stem cells) are given after treatment to help the bone marrow recover and produce healthy blood cells. Sources of stem cells are bone marrow and are allogeneic, autologous, or syngeneic
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Allogeneic
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Stem cells donated by someone else
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Autologous
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Stem cells removed from a person, stored, and then given back to the person following intensive treatment
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Syngeneic
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Stem cells donated by an identical twin
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Chemotherapy
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Treatment with anticancer drugs to destroy cancer cells by stopping them from growing or multiplying
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Radiation therapy
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Radiotherapy uses high-energy radiation from x-rays, neutrons, and other sources to kill cancer cells and shrink tumors
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External (chemotherapy)
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Uses a machine to aim high-energy rays at the cancer
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Internal (chemotherapy)
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Given internally by placing radioactive material that is sealed in needles, seeds, wires, or catheters directly into or near the tumor
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Systemic radiation therapy (chemotherapy)
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Giving a radioactive substance, such as a radiolabeled monoclonal antibody, that circulates throughout the body
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Surgery
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A procedure to remove a part of the body because of the presence of cancer
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Cystectomy
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Surgical removal of the bladder
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Cryosurgery
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Treatment performed with an instrument that freezes and destroys abnormal tissues
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Fulguration
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Destroying tissue using an electric current
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Hysterectomy
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Surgical removal of the uterus
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Laryngectomy
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An operation to remove all or part of the larynx (voice box)
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Laser (surgary)
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A device that concentrates light into an intense, narrow beam used to cut or destroy tissue. It is used in microsurgery, photodynamic therapy, and for a variety of diagnostic purposes
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Lumpectomy
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Surgery to remove the tumor and a small amount of normal tissue around it
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Mastectomy
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Surgery to remove the breast (or as much of the breast tissue as possible)
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Modified radial mastectomy
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Surgical procedure in which the breast, some of the lymph nodes in the armpit, and the lining over the chest muscles are removed
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Orchiectomy
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Surgical removal of one or both testicles
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Pneumonectomy
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Surgical removal of an entire lung
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Prostatectomy
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Surgical removal of part or all of the prostate
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Salpingo-oophorectomy
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Surgical removal of the fallopian tubes and ovaries
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Hormone therapy
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Treatment of cancer by removing, blocking, or adding hormones; also called endocrine therapy
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Antiandrogens
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Drugs used to block the production or interfere with the action of male sex hormones
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Luteinizing hormone-releasing hormone agonist
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A substance that closely resembles luteinizing hormone-releasing hormone (LH-RH), which controls the secretion of sex hormones; given to decrease secretion of sex hormones
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Palliative
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Cytoreduction; oncologic emergencies; neurosurgical procedures/pain control; nutritional support
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Prophylactic
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Excision of premalignant lesions
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Primary/definitive
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Local excision; en bloc dissection
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Rehabilitative
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Cosmetic and functional restoration
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Resection of metastases
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Lung;liver
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Supportive
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Insertion of access devices such as a porta catheter for infusion of drugs for chemotherapy; radiation implants
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Adenocarcinoma
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Cancer that begins in cells that line certain internal organs
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Atypical hyperplasia
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Benign (noncancerous) condition in which cells have abnormal features and are increased in number
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Benign
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Not cancerous; does not invade nearby tissue or spread to other parts of the body
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Cancer
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A term for diseases in which abnormal cells divide without control; can invade nearby tissues and spread through the bloodstream and lymphatic system to other parts of the body
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Carcinogen
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Any substance that causes cancer
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Carcinoma
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Cancer that begins in the skin or in tissues that line or cover internal organs
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Cyst
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A sac or capsule filled with fluid
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Ductal carcinoma in situ
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Abnormal cells that involve only the lining of a duct; cells have not spread outside the duct to other tissues in the breast
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Epidermoid carcinoma
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A type of cancer in which the cells are flat and look like fish scales; also called squamous cell carcinoma
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Familial polyposis
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An inherited condition in which numberous polyps (tissue masses) develop on the inside walls of the colon and rectum; increases the risk for colon cancer
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Fibroid
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A benign smooth muscle tumor, usually in the uterus or gastrointestinal tract; also called leiomyoma
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Hyperplasia
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An abnormal increase in the number of cells in an organ or tissue
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Large cell carcinomas
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A group of lung cancers in which cells are large and look abnormal when viewed under a microscope
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Lobular carcinoma in situ
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Abnormal cells found in the lobules of the breast; this condition seldom becomes invasive cancer; however, having lobular carcinoma in situ increases one's risk of developing breast cancer in either breast
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Malignant
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Cancerous; a growth with a tendency to invade and destroy nearby tissue and spread to other parts of the body
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Nonsmall cell lung cancer
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A group of lung cancers that includes squamous cell carcinoma, adenocarcinoma, and large cell carcinoma
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Oat cell cancer
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A type of lung cancer in which the cells look like oats when viewed under a microscope; also called small cell lung cancer
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Polyp
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A growth that protrudes from a mucous membrane
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Sarcoma
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A cancer of the bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue
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Small cell lung cancer
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A type of lung cancer in which the cells appear small and round when viewed under the microscope; also called oat cell lung cancer
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Squaous cell carcinoma
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Cancer that begins in squamous cells, which are thin, flat cells resembling fish scales; squamous cells are found in the tissue that forms the surface of the skin, the lining of the hollow organs of the body, and the passages of the respiratory and digestive tracts; also called epidermoid carcinoma
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Tumor
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An abnormal mass of tissue that results from excessive cell division; tumors may be either benign (not cancerous) or malignant (cancerous)