chapter 10 Cancer: Nutrient prevention & treatment – Flashcards

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Cancer
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Uncontrolled growth of abnormal cells that form a mass of tissue known as a tumor.
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Malignant tumor
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impairs body function & takes nourishment away from normal tissue.
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Oncology
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the study of cancer
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Oncologist
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medical doctor who specializes in the treatment of cancer
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epidemiologic
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based on observed associations in given populations, rather than cause-and-effect research
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epidemiologic
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Most cancer research is _______.
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Inflammation
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Physiologic Precursors of cancer: Chronic ____ as induced by obesity, diet, inactivity.
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radicals
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Physiologic Precursors of cancer: Free ____ inducing chromosomal changes (DNA)
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hyperinsulinemia
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the presence of excess insulin in the blood
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hyperinsulinemia insulin resistance
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______ & _____ are found with Gynecologic Cancer, Digestive tract cancers, Bladder & Prostate cancers, Leukemia, Non- Hodgkins lymphoma.
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Genetics
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associated with correlates of the metabolic syndrome.
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Saturated polyunsaturated CHO (sugar) fiber
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Cancer Etiology- Associated with: High intake of _____ fat, ____ fat, excess of ____ (____), low _____
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plant based antioxidants salt
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Cancer Etiology- Associated with: Low intake of _____-_____ foods & _________, & excess _____.
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Omega 2 fatty acids (fatty fish) iron vitamin D
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Cancer Etiology- Associated with: Low intake of _____ (_____), Possible excess of _____ intake & low _____ status.
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Inflammation
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High Iron levels are associated with ____.
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physical activity smoking chewing tobacco alcohol uv light carcinogens particles chemicals Nitrates inorganic arsenic
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Non-Diet Risk Factors of cancer are associated with low levels of _______, _______ or _____ ______, ______ intake, especially excessive, exposure to _____, exposure to ______ in the environment. _____ & ____ in the air, ______ in processed meats, _______ in water supplies.
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30 40 plant based fruits vegetables magnesium beans greens
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____% to ____% reduction in cancer risk with a diet rich in variety of ____-____ foods, especially ____ & ____; _____ rich foods ( ____ & ____)
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Protein calorie malnutrition wasting
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______-____ _____ & body ____ are common problems for clients who have cancer.
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Protein calorie malnutrition
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____-____ malnutrition & body wasting are common problems in cancer patients.
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morbidity mortality
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Nutritional deficits are a major cause of ____ & _____
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Surgery radiation chemotherapy immunotherapy bone marrow transplantation
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Major treatments for cancer include: 1)_____ 2)______ 3)______ 4)_______ 5)______
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nutritional complications
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Side effects of treatments compromise the nutritional status of affected clients, and more than 1/3 of all cancer deaths are related to _____.
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complications nutritional wasting weight healing reduce morbidity mortality life
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goals of nutritional therapy in cancer patients are to: Minimize the nutritional _____ of the disease. Improve ____ status prevent muscle ____ maintain _____ promote ____ _____ side effects decrease ______ & ______ Enhance quality of ______ and the overall effectiveness of treatment therapies.
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dietary fiber
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Adequate ____ may lessen the risk of colon cancer.
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fruits vegetables
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high intake of ___&___ is linked to a lowered incidence of many types of cancers. eat at least 5 servings a day.
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Whole grain grain
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consume ____ rather than processed or refined ____ & sugars.
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carcinogenic
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meat preparation by smoking, pickling, charcoal grilling, & use of nitrate containing chemicals may be ______.
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alcohol
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High ____ consumption is associated with liver, pancreatic, and billary cancers
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estrogen progesterone
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excess body fat stimulates the production of ___&___, which may intensify the growth of various cell types and may contribute to breast, gallbladder, colon, prostate, uterine, & kidney cancers.
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polyunsaturated monounsaturated fish olive
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High intake of ____ & ____ fats in ____ & ___ oils is presumed to be beneficial in lowering the risk of many types of cancers.
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Calcium
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a ___ rich diet is associated with lower incidence of colon cancer as it binds free fatty acids and bile salts in the lower gastrointestinal tract.
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anorexia metabolism nitrogen balance
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Cancer may cause ____, increased _____, and negative _____
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food nutrient energy body tissues
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systemic effects result in poor ___ intake, increased ____ &____ needs, and catabolism in _______.
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caloric
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Increased ______ intake to maintain weight and rebuild body stores.
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increased
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Protein needs are ____
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vitamin mineral
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___&___ supplementation is based upon the clients needs.
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better good
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encourage patient to eat more on days when feeling ____/ on _____ days.
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protein calories
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encourage intake of foods that have been modified to contain additional ___&____.
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milk cheese milkshakes pudding fish eggs nuts
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Foods that have been modified to contain additional protein and calories: - - - - - - -
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Protein calories
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Nutritional supplements that are high in ___ and or ___ should be encourage.
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between replacement
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Nutritional supplements that are high in protein and/or calories should be offered _____ meals and can be used as meal ___ if necessary.
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whole milk cheese peanut butter yogurt milk bread crumbs
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Increase protein and caloric content of foods by: substituting _______ for water in recipes. adding __ to dishes using ___ as a spread for fruits using ____ as a topping for fruis dipping meats in ____&____ before cooking
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calorie dense
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to help prevent fatigue Eat a large _____ breakfast when energy level is the highest,
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cold room temperature carbohydrate low toast crackers yogurt bananas cooked cereals fried
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Interventions to help with Nausea & Vomiting: eat ____ or _____ foods try high _____ & ____ fat foods, such as: ___,____,____,____,____. avoid ____ foods
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liquids roughage pectin
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Interventions to help with diarrhea: ensure adequate intake of ______ throughout the day to replace losses. avoid foods high in ____ they may exacerbate diarrhea Consume foods high in ____ to increase the bulk of the stool and to lengthen transition time in the colon
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inflammation
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chronic ______ is now recognized to promote cancer and is one of the common features found with metabolic syndrome.
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cancer
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inflammation promotes gene mutations leading to cells more prone to ______ development
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Free radicals free radicals
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an inflammatory response is typically accompanied by generation of _______. ________ are known to induce chromosomal changes in the deoxyribonucleic acid ( DNA_
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body weight overweight obesity
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excess ____, whether _____ or _____ is linked with the metabolic syndrome and risk of cancer.
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Hyperinsulinemia Hyperinsulinemia
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is felt to contribute to cancer through its promotion of tumor growth. ______ should be managed with diets and exercise to avoid an increase risk in cancer.
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gynecologic digestive tract bladder prostate leukemia non Hodgkin's lymphoma
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cancers related to obesity, hyperinsulinemia, and elevated blood glucose levels include the following - - - - - -
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Vitamin D
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evidence is showing that at least 17 different types of cancer are ________ sensitive.
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fish poultry
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Intake of ___&___ was related to lower risk of several cancers.
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arsenic
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the mineral ____ has been implicated in cancer development
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Antioxidants Vitamin E Vitamin C
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some nutrients that protect against cancer. _________, _________, _________.
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Antioxidants
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______ is found in dark green leafy vegetables and deep orange vegetables and fruits.
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Vitamin E
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_____ Is found in nuts and the germ portion of whole grains.
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Vitamin C
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_____ is found in berries, dark green leafy vegetables and citrus fruits.
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dark green leafy vegetables deep orange vegetables fruits
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_____,______,&______ Are some foods that have Antioxidants
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nuts germ whole grains
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____ & the ____ portion of _____ have Vitamin E.
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berries dark green leafy vegetables citrus fruits
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____, ____, & _____ Have vitamin C.
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antioxidants DNA
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foods containing ___ help prevent damage to ___, & reduce cancer risk.
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30 40
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The american institute for cancer research notes a reduction in risk of cancer by __% to ____% by following the diet and health guidelines for cancer prevention.
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plant based foods
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Increase intake of vitamins, minerals, & phytochemicals as naturally found in _______.
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Cruciferous
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Increase intake of vitamins, minerals, & phytochemicals as naturally found in plant based foods. This includes a variety of ________ vegetables that has long been associated with reduced cancer risk
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Broccoli Spinach cabbage brussels sprouts legumes fruits whole grains
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Cruciferous Vegetables that are associated with reducing the risk of cancer: 1)____, 2)_____, 3)______, 4)_____, 5)_______, 6)________, 7)_______.
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Sugar sugar based
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with a focus on a plant based diet, _____ intake is indirectly inhibited, avoidance of _____ drinks.
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Hyperinsulinemia Hyperinsulinemia
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Following the Plant-Based food Dietary Guidelines for reducing the risk of cancer helps normalize _____ among persons with the metabolic syndrome and likely minimizes risk of cancer development for such individuals. This is because of the reduced production of insulin like growth factor that occurs in the presence of ___________.
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Fiber
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Increase _____ intake by increased intake of vegetables and fruits.
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Vegetables Fruits
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Increase Fiber intake by increased intake of ___ & ____
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Insoluble fiber
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______ generally the skin and seeds of vegetables and fruits is believed to lower cancer risk.
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skin seeds
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Insoluble fiber is generally the ___ and ____ of fruits and vegetables.
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serum antioxidants
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Increasing vegetables and fruits is the impact on ____ levels of ____.
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High Plasma
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____ ____ levels of ascorbic acid, selenium, and carotenoids have been noted to protect against cancer.
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ascorbic acid selenium carotenoids
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High plasma levels of ___, ____ , & _____ protect against cancer.
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carotene
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High plasma concentrations of are associated with lowered mortality and lower cancer rates in the elderly.
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A C folate magnesium
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Dark green leafy vegetables provides: - Vitamins ___ & ____. - _____ & - ______
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Retinoids ( Vitamin A)
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______ (____) - Found in dark- green leafy & Orange vegetables & fruits have cancer prevention and treatment properties.
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Magnesium
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______ is known to reduce inflammation which is now being connected with cancer.
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unprocessed foods
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eating a variety of _____ reduce cancer risk is likely related to the complexity of nutrients found in them.
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Flavonoids (polyphenol)
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_____(______) are partially responsible for the cancer prevention effect of common vegetables and fruits.
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lower
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Normal-Weight, physically active individuals have _____ rates of cancer.
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inflammatory
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maintaining a normal body weight helps prevent an ______ state.
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inflammation
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Reducing _____ helps prevent cancer rush
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Riboflavin folate zinc
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Poor diet associated with alcohol abuse can lead to deficiencies of _____, _______, & _______, which promotes a high risk of throat, colon, liver, and breast cancers.
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alcohol
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Women with risk of breast cancer, avoidance of all ____ is advised.
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folate alcohol
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A diet containing adequate _____ may allow women with a risk of breast cancer to safely include moderate amounts of ______ as advised by the american heart association to lower risk of cardiovascular disease.
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Saturated
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Limit _____ fat intake because it is related to increased incidence of cancer.
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Polyunsaturated
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Most ______ fats are now felt to increase cancer risk because of their tendency to oxidize and form free radicals.
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oxidize free radicals omega 3 fatty acids
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most polyunsaturated fats are now felt to increase risk of cancer because of their tendency to ____ & form ______. The exception is the form of polyunsaturated fat known as ________.
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fatty fish fish oils
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The long-chain polyunsaturated fatty acids eicosapentaenoic acid (EPA) & docosahexaenoix acid ( DHA), are present in: ___-___ & __-__ which appear to be protective against various forms of cancer.
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fish EPA & DHA omega-3 fatty acids
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Reduction in inflammation levels from the inclusion of Fatty ____ with ___&___ _______ also may explain the association with reduced cancer risk.
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Omega 3 fatty acids
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several mechanisms whereby ____ reduced cancer risk. These include: -reduced production of fatty acid arachidonic acid -- - altered gene expression - alteration of estrogen metabolism - Changes in production of free radicals - reactive oxygen species - mechanisms involving insulin sensitivity - membrane fluidity
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Monounsaturated
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_______ fats, found in olive oil & the omega-3 fatty acid in ___-____ appear at least to have a neutral if not protective against cancer.
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saturated polyunsaturated
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One way to decrease the intake of ______ & _____ fats is to limit the total fat intake
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Low fat
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___-___ diets helps in the battle against cancer and other chronic illnesses such as heart disease & diabetes.
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salt
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minimize ____ intake to lower cancer risk, especially gastric cancer.
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salted fish
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Chinese- style _____ increases the risk for nasopharyngeal cancer. This should only be eaten in moderation.
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Salt
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The impact of ____ on risk of cancer may have to do with its ability to erode the protective mucous lining of the stomach. a similar irritant effect on the pharyngeal region may occur.
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Protective mucous
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salt has the ability to erode the ____ ____ lining of the stomach.
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aflatoxins
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____ that occur with moldy foods are known carcinogens.
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nitrosamines
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Avoid excess intake of foods cooked at hot temperatures, such as barbecued meats, reduces intake of harmful _________.
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Bladder Cancer
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_____ is the 4th leading type of cancer in men in the united states & ranks 9th in worldwide cancer incidence.
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cigarette smoking Chronic UTI'S
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___ & ____ are associated with an increased risk of bladder cancer.
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Cranberry
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___ juice has been shown to reduce risk of UTI's.
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chlorination arsenic phenacetin analgesics obesity
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Potential risk factors for bladder cancer include: -Drinking tap water with ____ by-products or ____. -Heavy consumption of ________ - containing ____. - _______
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Fruits Vegetables B vitamins 2 6 12 folate Retinal
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factors that reduce risk of bladder cancer include : ___ & ____ _____ ( __,__,__) ______& _____
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Retinol
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________Found in deep orange and dark green leafy vegetables are associated with a reduced risk of bladder cancer.
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b6 retinol
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Vitamin __ _ & ___ showed the strongest evidence of risk reduction in bladder cancer.
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Broccoli cauliflower brussels sprouts cabbage
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Compounds in Cruciferous vegetables such as: ___, _____, _____, & _____. Have an anti-carcinogenic effect on bladder cancer.
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mushroom C
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Two ____ extracts, when combined with moderate amounts of vitamin ___, became highly cytotoxic, resulting in 90% cell death related to bladder cancer.
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Breast Cancer weight
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_____ is the 2nd leading cause of cancer death among U.S. woman. & excess ___ appears to contribute to risk.
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high density lipoprotein (HDL) Overweight obese
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A low level of _____ (___) _____, as found in the metabolic syndrome, is related to increased breast cancer in ____ & ____ woman
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Insulin resistant High insulin
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The common link with obesity, type 2 diabetes and breast cancer appears to be _____ _____ with ____ ____ levels.
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Fat
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Dietary ___ intake, regardless of the type, contributes to risks of postmenopausal breast cancer
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