breast lesions and cervical cancer – Flashcards

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benign breast disorder
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any noncancerous breast abnormality that can cause pain and discomfort
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malignant breast disorder
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neoplastic disease where normal breast cells transform into malignant cells. most common cancer and 2nd leading cause of cancer deaths in women
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Carcinoma
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A malignant tumor that occurs in the epithelial tissue. It tends to infiltrate and give rise to metastases.
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60 years and older
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the peak age for developing cancer
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invasive ductal carcinome
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most common breast cancer. starts in the ducts wall and invades the fatty breast tissue. 85% of cases
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invasive lobular carcinoma
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breast cancer which terminal lobular units of breast ducts and is frequently located in the upper outer quadrant of the breast. by the time it is discovered the prognosis is usually poor
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estrogen and progesteron
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hormones which breast cancer's growth rate is regulated by
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epithileal cells that line the mammary ducts
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place in the breast where breast cancer starts
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Paget's disease
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originates in the nipple and typically occurs with the invasive ductal carcinoma
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tumor size, extent of lymph node involvement, evidence of metastasis
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three classifications of breast cancers
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80%
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percentage of women in whom breast cancer have no documented risks factors
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nonmodifiable risk factors
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risk factors for breast cancer that cannot be changed
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modifiable risk factors
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risk factors for breast cancer that can be changes
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nonmodifiable risks
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female, >50, BRCA-1 or 2 genes, hx of ovarian, colon, breast ca, increased breast density, family hx of breast ca, white race, exposure to breast radiation, early menarche or late menopause
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modifiable risks
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no children or births after 30, postmenopausal use of estrogens and progestins, did not breastfeed for at least a year, alcohol, smoking, obesity, high fat diet, sedentary lifestyle
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do not have a reduced number of menstrual cycles
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not being pregnant or breast feeding for longer than a year increases breast cancer risks because:
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estrogen
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Early menarche 55 represents a nonmodifiable risk factor for breast cancer because of the lifetime of increased exposure to:
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alcohol consumption
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boosts the level of estrogen in the blood stream
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smoking
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exposure to carcinogenic agents
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fat cells
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produce and store estrogen and so create higher estrogen levels
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sedentary lifestyle
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increases body fat which houses estrogen
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cancerous lesions
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are usually fixed, painless and in the upper quadrants
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birth control use for over ten years
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a contraceptive which is modifiable risk factor for breast cancer
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intraductal papilloma
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a benign, wart like growth found in the mammary ducts near the nipple has a watery discharge 40-60yrs old
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atypia cells
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increases the risk of breast cancer four to fivefold
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treatment of intraductall papilloma
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surgical removal and part of the duct and tested to rule out cancer
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duct ectasia
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a dilation and inflammation of the ducts behind the nipple, benign and most common in perimenopausal women, nipple discharge green, brown, straw, reddish, gray or cream color toothpaste like discharge
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painless and fixed in outer upper quadrants
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breast lumps more likely to be cancerous
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family history
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7% of breast cancer patients have this risk factor
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simple mastectomy
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surgical removal of all the breast tissue, nipple and aerola only done if not metastasized
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modified radical mastectomy
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removal of all breast tissue, axillary nodes, some chest muscle but not pectoralis major to avoid concave appearance and is better for reconstructive surgery
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lymph node removal
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done if sentinel test is positive has a high rate of nerve damage
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BRCA-1 and BRCA-2
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genes which increase risk of breast cancer by 75%, and 30% for ovarian cancer
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radiation therapy
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side effects include inflammation, local edema, anorexia, swelling and heaviness of the breast, sunburn skin changes, fatiugue
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chemotherapy
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the use of drugs that are toxic to all cells and interfere with the cells ability to reproduce, especially malignant cells
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chemotherapy side effects
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side effects nausea and vomiting, diarrhea or constipation, hair loss, weight loss, stomatitis (mouth lesions), fatigue and immunosupression
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blood counts are too low
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chemotherapy would be stopped when:
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fibroadenomas
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common benign solid breast tumors that can be stimulated by external estrogen, progesterone, lactation and pregnancy
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mastitis
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an infection of the connective tissue in the breast that occurs primarily in the lactating or engorged women
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lung cancer
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first leading cause of death from cancer in women
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breast cancer metastasizes
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bone, lungs, lymph nodes, liver and brain and almost all organs of the body
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localized cancer treatment
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surgery and radiation
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systemic breast cancer treatment
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chemotherapy, hormonal therapy, immunotherapy
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endocrine therapy
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blocks the effect of estrogen which stimulates the the growth and division of healthy cells in the breasts
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endocrine therapy side effects
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hot flashes, bone pain, fatigue, nausea, cough, dyspnea and headache
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immunotherapy
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used as an adjunct to surgery is an attempt to stimulate the body's natural defenses to recognize and attack cancer cells
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Herceptin
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the first monoclonal antibody approved for breast cancer
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HER-2/neu
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a protein produced but the tumor and are associated with a more aggressive form of disease and a poorer prognosis
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Trastuzumab
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blocks the effect of the HER-2 protein to inhibit the growth of cancer cells
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side effects of trastuzumab
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cardia toxicity, vascular thrombosis, hepatic failure, fever, chills, nausea, vomiting, and pain with the first infusion
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clinical manifestations of breast cancer
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continued and persistent changes in the breast, a lump or thickening in one breast, persistent nipple irritation, unusual breast swelling or asymmetry, lump or swelling in the axilla, skin color or texture changes, nipple retraction, tenderness or discharge
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palpatable lumps in breast
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means the cancer has been there for quite some time
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Disturbed body image related to loss of body part, loss of femininity, loss of hair due to chemotherapy
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Nursing diagnoses for a woman diagnosed with breast cancer
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Fear related to diagnosis of cancer, prognosis of disease
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nursing diagnoses for cancer diagnoses
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Educational deficit related to cancer treatment options, reconstructive surgery decisions, breast self examination
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nursing diagnosis for woman with decisions to make about breast cancer
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benign breast masses
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frequently painful, firm rubbery mass, bilateral masses, induced nipple discharge, clearly delineated margins, no skin dimpling, no nipple retraction, mobile nodule not affixed to chest wall, no bloody discharge
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malignant masses
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hard to palpate, painless, irregularly shaped and poorly delineated, immobile and fixed to chest wall, skin dimpling, nipple retraction, unilateral mass, bloody, serosanguineous or serous nipple discharge, spontaneous nipple discharge
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cervical cancer
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cancer of the uterine cervix, one of the most treatable cancers when detected at an early stage. a neoplastic growth of cervix, 1 in 20 women develop it between the ages of 40-49
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papanicolaou test (PAP)
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detects cervical cancer and precancerous lesions by detecting cervical dysplasia (disordered growth of abnormal cells)
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HPV
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linked to cervical cancer because 90% of cancer cells contain it spread through sexual contact
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signs and symptoms of cervical cancer
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mostly asymptomatic but can be pain, genital warts and or vaginal discharge
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cervial cancer treatment
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cryotherapy (destroys abnormal cancer cells by freezing), cone biopsy or conization, (removes a cone shaped section of the cervical tissue, laser therapy, hysterectomy, radiation, chemotherapy
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risk factors for cervical cancer
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early age of first intercourse (with in first year of menarche), lower socioeconomic status, promiscuous male partners, unprotected intercourse, family history of cervical cancer, sex with uncircumcised men, genital herpes, chronic chlamydia, multiple sex partners, smoking, immunocompromised , HIV, oral contraceptive use, moderate dysplasia on Pap smear in past five years, HPV infection
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first sign of cervical cancer
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abnormal vaginal bleeding and or vaginal discomfort, malodorous discharge, dysuria or maybe asymptomatic
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nursing management for cervical cancer
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primary focus is prevention through education
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education for preventing cervical cancer
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ID high risk behaviors and teach them how to take steps to avoid STI's, avoid having sex at young age, faithfully use barrier methods of contraception, avoid smoking an drinking, receive the HPV vaccine, have regular Pap smears
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Secondary prevention of cervical cancer
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education focus is on reducing or limiting the area of cervical dysplasia
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tertiary prevention of cervical cancer
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education focuses on minimizing disability or spread of cervical cancer
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cervical dysplasia
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disordered growth of abnormal cells in the cervix
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colposcopy
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a microscopic examination of the lower genital tract using a magnifying instrument. specific patterns of cells that correlate with cancer can be seen
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Stage 2 breast cancer
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mass is approximately 1to 2 inches in diameter and the 3 adjacent lymph nodes are positive
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Stage 0
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early stage breast cancer that is extremely localized
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Stage 3
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Breast cancer tumor over 2 inches and has spread to lymph nodes and tissues
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Stage 4
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breast cancer that has metastised
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