Missense Mutations – Flashcards
Unlock all answers in this set
Unlock answersquestion
Missense mutations
answer
Code for a different amino acid. A missense mutation changes a codon so that a different protein is created, a non-synonymous change.
question
Conservative mutations:
answer
Result in an amino acid change. However, the properties of the amino acid remain the same (e.g., hydrophobic, hydrophilic, etc). At times, a change to one amino acid in the protein is not detrimental to the organism as a whole. Most proteins can withstand one or two point mutations before their functioning changes.
question
Non-conservative mutations
answer
Result in an amino acid change that has different properties than the wild type. The protein may lose its function, which can result in a disease in the organism.
question
Non-conservative mutations
answer
Result in an amino acid change that has different properties than the wild type. The protein may lose its function, which can result in a disease in the organism.
question
Silent mutations
answer
Code for the same amino acid. A silent mutation has no effect on the functioning of the genome. A single nucleotide can change, but the new codon specifies the same amino acid, resulting in an unmutated codon.
question
Silent mutations
answer
Code for the same amino acid. A silent mutation has no effect on the functioning of the genome. A single nucleotide can change, but the new codon specifies the same amino acid, resulting in an unmutated codon.
question
Silent mutations
answer
Code for the same amino acid. A silent mutation has no effect on the functioning of the genome. A single nucleotide can change, but the new codon specifies the same amino acid, resulting in an unmutated codon.