micro test 4 2011 – Flashcards

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state of not being in good health
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Disease
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often refered to as protozoans or worms
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parasite
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reffering to bacteria, virus, or fungus that (an organism) that has potential to cause disease
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pathogen
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a pathogen growing in or on the host-has invaded the host
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infection
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ability of the pathogen to spread to other tissues in the body
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invasiveness
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degree or intensity of pathogenicity
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virulence
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ability of the pathogen to secrete toxins
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infectivity
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an infection in which the pathogen grows massively in the body, found in blood and usually leads to death.
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septicemia
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scientific study of disease
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pathology
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study of the cause of a disease
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etiology
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study of the development of a disease
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pathogenesis
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host
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can prevent pathogens from causingan infection
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normal microbiota
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microbes that are present for various periods and then disappear
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symbiosis
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both orgamisms benefits

ex. plants

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mutualisim
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one orgamism benefits and the other is unaffected
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Commensalism
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one benefits and the other is harmed

 

ex. worms being in the body, worms have a place to live and feed and the body is harmed

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parasitism
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where noraml microbiotas can prevent pathogens from causing and infection.
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microbial antagonism
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pathogens that do not cause disease under normal conditions but can cause disease under special conditions

 

ex. e coli can gain access to other body parts.

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Opportunistic
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cannot be measured, is a subjective change in body functions
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symptom
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measurable changes in the body
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sign
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a specific group of symptoms or signs that always accompanies a specifis diseace
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syndrome
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directly or indirectly from one host to another
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communicable
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easily spread from one person to another
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contagious
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caused by microorgamisms that normally grow outside the human body and are not transmitted from one host to another
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noncommunicable
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number of people contracting the disease

 

new cases

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incidence
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number of cases at a particualar time

 

existing

 

note: a period of time

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prevalence
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only an occasional case

 

ex. typhoid fever

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sporadic
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constantly present in the general population

 

ex. common cold

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endemic
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many ppl acquire the disease in a relatively short period of time

 

ex. flu

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epidemic
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world wide epidemic

 

ex. AIDS

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pandemic
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a disease that develops rapidly but lasts a short period of time
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acute disease
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a disease that develops more slowly and body reactions may be less severe but will probably be continual or last a long time

 

ex. Mono, TB

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chronic disease
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 somewhere between acute and chronic

 

ex. rare brain disease

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subacute disease
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causative agent remains inactive for a time and then becomes active to produce symptoms of the disease

 

ex. shingles

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latent
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new diseases and diseases with increasing incidences
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EIDS

emerging infectious diseases

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affects a small area of the body

 

ex. boil or acne

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local infection
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spread throughout the body via circulatory system
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systemic infection
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can occur after the host is weakened from a primary infection
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secondary infection
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does not cause any signs of disease in the host

 

 

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unapparent or subclinical infection
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a continual SOURCE of infection
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reservior
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diseases that affect wild and domestic animals and can be transmitted to humans

 

ex. rabies

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zoonoses
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involves close physical contact between the source of the disease and suspectable host
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direct transmission
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constitutes indirect contact
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transmission by fomite (indirect)
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tranmission via saliva or mucus in coughingor sneezing
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droplet transmission
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transmission by a medium such as water, food or air
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vehicle transmission
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refers to pathogens carried on water droplets or dust for a distance greater than 1 meter
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airborne transmission
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carries pathogens from one host to another by both mechanical and biological transmission
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airborne vectors
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presence of immunity to a diease in most of the population
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herd immunity
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on an animals body and spread by contact
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mechanical or passive transmission
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spread by when the animal actually bites or scratches
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active or biological transmission
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pathogens exits by coughing or sneezing
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respiratory tract
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pathogens exit by salivia or feces
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in infection that occurs in a place where they are to be healed. like getting an infection from a hospital
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Nosocomial Infection
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patients with burns, surgical wounds and suppressded immune systems are the most susceptible to nonsocomial infections are known as what
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compromised host
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what are things/ways that nonsocomial infeactions can be transmitted
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catheters, syringes, and respiratory devices.
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is one that makes the body more  susceptible to disease or alters the course of a disease
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predisposing factor
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the time interval between the initial infection and the first appearance of signs and symptoms
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incubation period
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is characterized by the appearance of the first mild sings and symptoms
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prodromal period
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the disease is at its height and all disease signs and symptoms are apparent
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period of illness
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the signs and symptoms subside
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period of decline
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body turns to its normal state and health is restored
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period of covalesence
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the study of the transmission, incidence and frequency of disease is..
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epidemiology
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data about infected people are collected and analyzed, this is known as what
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descriptive epidemiology
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a group of infected people is comapred with and uninfected group, this is known as what
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analytical epidemiology
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contrilled experiments designed to test hypotheses are performed in what
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experimental epidemiology
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is the ability of a pathogen to produce a disease
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pathogenicity
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is the degree of pathogenicity
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virulence
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the specific route by which a particular pathogen gains access to the body
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portal of entry
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is the number of microbes in a dose that will 50% of inoculated test animals
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LD50
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is the dose required to produce a demonstratable infection in 50% of the test animals
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ID50
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____ destroy white blood cells
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leukocidins
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_____ lyse red blood cells
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hemolysins
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poisonus substances produced by microogranisms are called what
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toxins
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___ refers to the presence of toxins in the blood
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toxemia
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__ is the ability to produce toxins
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toxigenicity
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___ are produced inside some baterieria as some if their growth and metabolism and re released into the surrounding area.

___ produce the disease symptoms

___ are usually produced by gram (-) bacteria

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exotoxins
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antibodies produced against exotoxins are called what
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antitoxins
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___ work by destroying particular parts of the hosts cell or by inhibiting metabolic functions.
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Cytotoxins
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___ prevent nerve transmission

ex. tatanus

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neurotoxins
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___ induce fluid and electrolyte loss from the host cell
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entertoxins
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___ are released wih bacterial cell death or by the action os antibiotics and antibodies

____ are lipopolysaccharides that form a normal part of the cell wall in gram negative bacteria

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endotoxin
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__ are visible signs of viral infection
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cytopathic effects (CPE)
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__ is cell death
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cytocidal effects
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__ is the cell damage but not death
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noncytocidal effects
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the ability to ward off disease through body defences is called
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resistance
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__ is lack of resistance
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susceptibility
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___ refers to all body defences that protect the body against and kind of pathogen
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nonspecific resisitance
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___ refers to defences against specific microorganisms
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specific resistance
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__ is an oily substance produced by the skin
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sebum
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when phagocytes have the ability to stick to the lining of the blood vessels, this is called what
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margination
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___ also has the ability  to squeeze through blood vessels
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emigration
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___ is the accumulation of damaged tissue and dead microbes
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pus
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a systematic response that your body does
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fever
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__ consists of a group of serum proteins that activate on another to destroy invading microorganisms
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complement system
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__ are antiviral proteins produced in response to a viral infection
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interferons
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___ is a individuals geneticallt predetermined resistance to certain diseases
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innate resistance
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__ is the study of reastions between antibodies and antigens
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serology
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___ is the ability if the body to specifically counteract foreign orgamisms
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immunity
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___ is a specific resistance to infection developed during the life of the individual
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acquired immunity
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___ is immunity resluting from infection
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naturally accquired immunity
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___ occurs when antibodies are transferred from a mother to a fetus
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naturally accquired passive immunity
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___ results from a vaccine
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artificially acquired active immunity
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__ refers to humoral antibodies acquired by injection
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artificially acquired passive immunity
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___ involves specializedlymphocytes called T-cells
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cell-mediated immunity
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__ is a chemical sudstance that causes the body to produce specific antibodies
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antigen
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___ is a protein produced by B-cells in response to presence of an antiogen and is capable of combinging specifically with that antigen
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antibody
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___ is a programmed cell death that unneeded lynphocytes undergo
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apoptosis
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___ shows IgM vs IgG
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antibody titer
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