Exam II – Microbiology – Flashcards
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| 7 Infectious Viral Pathways |
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| 1) Inhibit macromolecular synthesis 2) Hydrolytic enzymes 3) Disrupt cell structure 4) Viral-specific proteins added to host cell membrane 5) High concentration of viral proteins can be toxic to host 6) Disrupt host chromosomes 7) Host transformed to malignant cell |
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| 10 Characteristics to Classify Viruses |
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| 1) Host 2) RNA/DNA? ss or ds3) Capsid type/shape 4) +/- envelope 5) Capsid size 6) (if polyhedral) Number of capsomeres7) Immunological attributes 8) Site of replication in the host 9) Disease/Effect 10) How transmitted? |
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| 3 Methods to Classify Bacteria |
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| 1) Intuitive-stems from familiarity with the microbes 2) Numerical Taxonomy-comparing characteristics of known & unknown bacteria with a computer (65% genus; 85% species). 3) Genetic Testing-Using a probe (unique complement to a specific sequence of the bacteria) in the unknown bacteria. |
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| 8 Characteristics to Classify Bacteria |
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| 1) Morphology 2) Cultural 3) Probing 4) Chemical 5) Pathogenicity 6) Antigenic 7) Genetic 8) Ecological |
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| Pasteurellaceae |
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Oxidase + Motility - Na+ Ion - Common Antigen - |
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| Enterobacteriaceae |
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Oxidase - Motility + Na+ Ion - Common Antigen + |
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| Virbionaceae |
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Oxidase + Motility + Na+ Ion + Common Antigen - |
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| Eclipse Period |
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| Period of time between initial intracellular infection and the appearence of the first mature virus in the cell. |
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| Latent Period |
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| The time it takes for intracellular (before bursting) viral progeny assembly to occur. |
