Ch. 26 Renal Filtration – Flashcards

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question
Mike's injury is going to impact his urinary system significantly. Which of the following is NOT a function of the urinary system?
answer
The kidney releases erythropoietin, a hormone that functions in the maturation of white blood cells.
question
Mike's injury caused his ureter to be torn away at the hilum of the kidney. What internal kidney structures funnel the urine into the renal pelvis of the ureter?
answer
the calyces
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The first step in the formation of urine is the generation of filtrate from the blood plasma by filtration. In what part of the nephron does the formation of filtrate occur?
answer
glomerular capsule
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There are multiple pressures involved in controlling glomerular filtration and the formation of filtrate. Which is the pressure that opposes the formation of filtrate by drawing water out of the filtrate and back into the plasma?
answer
blood colloid osmotic pressure (BCOP)
question
Which of these is NOT a property of countercurrent multiplication?
answer
It is opposed by the vasa recta.
question
Which statement best describes the relationship between Type 2 diabetes and the transport maximum (Tm)?
answer
The continued high concentration of glucose in blood could cause the chronic transport maximum to be exceeded. This may result in membrane damage that affects glucose reabsorption as well as an inability to regulate blood glucose to normal levels.
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The step in kidney function in which fluid is forced out of the blood includes moving fluid __________.
answer
from glomerulus to glomerular capsule
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During filtration, anything that is small enough to pass through all three layers of the filtration membrane will become part of the filtrate. Sometimes, the least porous layer of this membrane becomes clogged and then glomerulonephritis may occur. What is the name of the most porous layer of the filtration membrane?
answer
fenestrated epithelium
question
What triggers the movement of water out of the descending limb?
answer
Ions are transported out of the ascending limb, and the resulting concentration gradient in the peritubular fluid pulls water out of the descending limb.
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Antidiuretic hormone (ADH) causes __________.
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a decrease in urine volume but an increase in solute concentration
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One of the organic substances not normally excreted by the kidney is __________.
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protein
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All of the following processes are functions of the urinary system EXCEPT __________.
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production of urea
question
Which of the following statements about aldosterone is NOT correct?
answer
Aldosterone increases sodium reabsorption by increasing the number of Na+-K+ ATPase pumps in the luminal membrane of the proximal tubule.
question
Which of the following statements about ADH (antidiuretic hormone) is correct?
answer
ADH is released by the posterior pituitary gland
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What is the osmolarity of the filtrate at the end of the proximal tubule?
answer
isotonic- 300 mOsm
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In overhydration, what would be the levels of ADH (high, normal, or low) and what would be the osmolarity of the urine?
answer
ADH - low; 100 mOsm (urine)
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In severe dehydration or blood loss, what would be the levels of ADH and what would be the urine flow rate?
answer
ADH - high; low urine flow rate (0.25 ml/min)
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Sheila has been exercising at peak performance for about 60 minutes. She did not hydrate as effectively as she should have and as a result, her urine is deep yellow and low in volume. Which of the following is the most likely mechanism affecting this?
answer
blood colloid osmotic pressure
question
The main site for water reabsorption along the nephron is the __________.
answer
proximal convoluted tubule
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Which of these hormones causes the kidney to increase the body's content of sodium?
answer
aldosterone
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A diuretic drug called thiazide increases water loss by reducing ion reabsorption in the proximal and the distal convoluted tubules. Which of the following answer choices correctly pertains to this statement?
answer
obligatory water reabsorption is thus reduced
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The main force(s) opposing glomerular filtration is (are) __________.
answer
blood colloid osmotic pressure and capsular hydrostatic pressure
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A decrease in blood albumin level will cause a decrease in blood colloid osmotic pressure. This will lead to a rise in the net glomerular filtration pressure. Are these two statements true or false?
answer
both statements are true.
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Besides being very painful, a blockage in a ureter due to kidney stones or external pressure is serious because it leads to an increase in capsular hydrostatic pressure. What is the consequence of this increase in pressure?
answer
The glomerular filtration rate decreases because the net filtration pressure is a negative value.
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Chronic and acute renal failure impairs all of the functions carried out by the kidneys and, as a consequence, the functions of most other body systems. Which of the following renal functions is matched incorrectly?
answer
erythropoietin; digestion
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Some patients with kidney failure regularly undergo a procedure called hemodialysis to cleanse their blood. This procedure thus effectively replaces which of the following kidney components.
answer
nephrons
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Which of the choices below best describes the glomerular filtration rate (GFR)?
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the volume of filtrate created by the kidneys per minute
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Which of the following best describes the passive force that creates filtrate?
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glomerular hydrostatic pressure (GHP)
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What is the primary regulatory mechanism that maintains glomerular filtration rate (GFR)?
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autoregulation
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Which of the following GFR-regulating mechanisms is initiated by cells of the juxtaglomerular complex?
answer
autonomic regulation
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The myogenic mechanism of renal autoregulation primarily involves smooth muscle in which blood vessels?
answer
afferent arterioles
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In the event of a severe increase in systemic blood pressure, what mechanism would increase GFR?
answer
release of ANP and BNP
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What enzyme is released by the juxtaglomerular complex to regulate GFR?
answer
renin
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Which of the choices below best describes the autonomic mechanism for regulating GFR?
answer
Sympathetic fibers override local controls to decrease the GFR.
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